Alfonso Perez

Summary

Affiliation: Takeda Global Research and Development Center
Country: USA

Publications

  1. doi request reprint Efficacy and safety of pioglitazone/metformin fixed-dose combination therapy compared with pioglitazone and metformin monotherapy in treating patients with T2DM
    Alfonso Perez
    Takeda Global Research and Development Center, Inc, Lake Forest, IL, USA
    Curr Med Res Opin 25:2915-23. 2009
  2. doi request reprint Effects of pioglitazone and metformin fixed-dose combination therapy on cardiovascular risk markers of inflammation and lipid profile compared with pioglitazone and metformin monotherapy in patients with type 2 diabetes
    Alfonso Perez
    Takeda Global Research and Development Center, Inc, Deerfield, IL, USA
    J Clin Hypertens (Greenwich) 12:973-82. 2010
  3. doi request reprint A comparison of all-cause mortality with pioglitazone and insulin in type 2 diabetes: an expanded analysis from a retrospective cohort study
    Jiao Yang
    Takeda Development Center Americas Inc, Deerfield, IL, USA
    Curr Med Res Opin 30:2223-31. 2014
  4. ncbi request reprint Pioglitazone plus a sulphonylurea or metformin is associated with increased lipoprotein particle size in patients with type 2 diabetes
    Alfonso Perez
    Takeda Global Research and Development, Inc, 475 Half Day Road, Suite 500, Lincolnshire, IL 60069, USA
    Diab Vasc Dis Res 1:44-50. 2004
  5. pmc Comparing pioglitazone to insulin with respect to cancer, cardiovascular and bone fracture endpoints, using propensity score weights
    Carlos Vallarino
    Takeda Global Research and Development Center, Inc, Deerfield, IL 60015, USA
    Clin Drug Investig 33:621-31. 2013
  6. ncbi request reprint A comparison of pioglitazone and rosiglitazone for hospitalization for acute myocardial infarction in type 2 diabetes
    Charles M Gerrits
    Department of Global Pharmacoepidemiology, Takeda Global Research and Development, Inc, Deerfield, IL, USA
    Pharmacoepidemiol Drug Saf 16:1065-71. 2007

Collaborators

Detail Information

Publications6

  1. doi request reprint Efficacy and safety of pioglitazone/metformin fixed-dose combination therapy compared with pioglitazone and metformin monotherapy in treating patients with T2DM
    Alfonso Perez
    Takeda Global Research and Development Center, Inc, Lake Forest, IL, USA
    Curr Med Res Opin 25:2915-23. 2009
    ..Studies have shown that many patients with type 2 diabetes do not achieve optimal glycemic control, and progression of diabetes over time requires more than one pharmacotherapy to achieve glycemic goal...
  2. doi request reprint Effects of pioglitazone and metformin fixed-dose combination therapy on cardiovascular risk markers of inflammation and lipid profile compared with pioglitazone and metformin monotherapy in patients with type 2 diabetes
    Alfonso Perez
    Takeda Global Research and Development Center, Inc, Deerfield, IL, USA
    J Clin Hypertens (Greenwich) 12:973-82. 2010
    ..0001 vs metformin). Overall, adverse events were not higher with the FDC. Thus, treatment with the FDC resulted in improved levels of CV biomarkers, which were better than or equal to monotherapy...
  3. doi request reprint A comparison of all-cause mortality with pioglitazone and insulin in type 2 diabetes: an expanded analysis from a retrospective cohort study
    Jiao Yang
    Takeda Development Center Americas Inc, Deerfield, IL, USA
    Curr Med Res Opin 30:2223-31. 2014
    ..The objectives of this study were to assess and compare all-cause mortality rates between pioglitazone (PIO) and insulin (INS)...
  4. ncbi request reprint Pioglitazone plus a sulphonylurea or metformin is associated with increased lipoprotein particle size in patients with type 2 diabetes
    Alfonso Perez
    Takeda Global Research and Development, Inc, 475 Half Day Road, Suite 500, Lincolnshire, IL 60069, USA
    Diab Vasc Dis Res 1:44-50. 2004
    ..To determine the effect of pioglitazone plus metformin or a sulphonylurea on lipoprotein particle size and subclass distribution in patients with type 2 diabetes...
  5. pmc Comparing pioglitazone to insulin with respect to cancer, cardiovascular and bone fracture endpoints, using propensity score weights
    Carlos Vallarino
    Takeda Global Research and Development Center, Inc, Deerfield, IL 60015, USA
    Clin Drug Investig 33:621-31. 2013
    ....
  6. ncbi request reprint A comparison of pioglitazone and rosiglitazone for hospitalization for acute myocardial infarction in type 2 diabetes
    Charles M Gerrits
    Department of Global Pharmacoepidemiology, Takeda Global Research and Development, Inc, Deerfield, IL, USA
    Pharmacoepidemiol Drug Saf 16:1065-71. 2007
    ..Recent studies have raised concerns about potential increased cardiovascular (CV) risk in type 2 diabetes patients treated with some peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonists...