STEVEN YOUNGENTOB

Summary

Affiliation: SUNY Upstate Medical University
Country: USA

Publications

  1. pmc Fetal nicotine exposure increases preference for nicotine odor in early postnatal and adolescent, but not adult, rats
    Nicole M Mantella
    Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, Syracuse, New York, United States of America
    PLoS ONE 8:e84989. 2013
  2. pmc Gestational naltrexone ameliorates fetal ethanol exposures enhancing effect on the postnatal behavioral and neural response to ethanol
    Steven L Youngentob
    Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Exp Biol Med (Maywood) 237:1197-208. 2012
  3. pmc Experience-induced fetal plasticity: the effect of gestational ethanol exposure on the behavioral and neurophysiologic olfactory response to ethanol odor in early postnatal and adult rats
    Steven L Youngentob
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 121:1293-305. 2007
  4. pmc Fetal ethanol exposure increases ethanol intake by making it smell and taste better
    Steven L Youngentob
    Department of Neuroscience and Physiology and the Developmental Exposure Alcohol Research Center, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Proc Natl Acad Sci U S A 106:5359-64. 2009
  5. ncbi request reprint Odorant identification and quality perception following methyl bromide-induced lesions of the olfactory epithelium
    Steven L Youngentob
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 120:1346-55. 2006
  6. pmc Predicting odorant quality perceptions from multidimensional scaling of olfactory bulb glomerular activity patterns
    Steven L Youngentob
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 120:1337-45. 2006
  7. pmc A method for the rapid automated assessment of olfactory function
    Steven L Youngentob
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, Institute for Human Performance, 750 East Adams Street, Syracuse, NY 13210 USA
    Chem Senses 30:219-29. 2005
  8. pmc Adolescent ethanol experience alters immediate and long-term behavioral responses to ethanol odor in observer and demonstrator rats
    Amber M Eade
    Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, New York, USA
    Behav Brain Funct 5:23. 2009
  9. pmc The consequence of fetal ethanol exposure and adolescent odor re-exposure on the response to ethanol odor in adolescent and adult rats
    Amber M Eade
    Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, NY, USA
    Behav Brain Funct 5:3. 2009
  10. pmc Ontogeny of the enhanced fetal-ethanol-induced behavioral and neurophysiologic olfactory response to ethanol odor
    Amber M Eade
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, New York, USA
    Alcohol Clin Exp Res 34:206-13. 2010

Research Grants

  1. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 1999
  2. In utero ethanol experience and olfactory plasticity
    STEVEN YOUNGENTOB; Fiscal Year: 2007
  3. In utero ethanol experience and olfactory plasticity
    STEVEN YOUNGENTOB; Fiscal Year: 2006
  4. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2003
  5. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2002
  6. DEVELOPING A RAPID SCREEN TO DETECT OLFACTORY MUTANTS
    STEVEN YOUNGENTOB; Fiscal Year: 2001
  7. DEVELOPING A RAPID SCREEN TO DETECT OLFACTORY MUTANTS
    STEVEN YOUNGENTOB; Fiscal Year: 2000
  8. DEVELOPING A RAPID SCREEN TO DETECT OLFACTORY MUTANTS
    STEVEN YOUNGENTOB; Fiscal Year: 1999
  9. In utero ethanol experience and olfactory plasticity
    Steven L Youngentob; Fiscal Year: 2010
  10. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2001

Collaborators

Detail Information

Publications19

  1. pmc Fetal nicotine exposure increases preference for nicotine odor in early postnatal and adolescent, but not adult, rats
    Nicole M Mantella
    Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, Syracuse, New York, United States of America
    PLoS ONE 8:e84989. 2013
    ..Moreover, they add to a growing literature demonstrating chemosensory mechanisms by which patterns of maternal drug use can be conveyed to offspring, thereby enhancing postnatal vulnerability for subsequent use and abuse...
  2. pmc Gestational naltrexone ameliorates fetal ethanol exposures enhancing effect on the postnatal behavioral and neural response to ethanol
    Steven L Youngentob
    Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Exp Biol Med (Maywood) 237:1197-208. 2012
    ..Thus, gestational naltrexone may also have a neuroprotective and/or neuroproliferative impact on olfactory development...
  3. pmc Experience-induced fetal plasticity: the effect of gestational ethanol exposure on the behavioral and neurophysiologic olfactory response to ethanol odor in early postnatal and adult rats
    Steven L Youngentob
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 121:1293-305. 2007
    ..These data provide evidence for an important relationship between prenatal ethanol experience and postnatal behavioral responsiveness to the drug that is modulated or determined by olfactory function...
  4. pmc Fetal ethanol exposure increases ethanol intake by making it smell and taste better
    Steven L Youngentob
    Department of Neuroscience and Physiology and the Developmental Exposure Alcohol Research Center, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Proc Natl Acad Sci U S A 106:5359-64. 2009
    ..g., marijuana) drugs have noteworthy chemosensory components, our findings have broad implications for the relationship between maternal patterns of drug use, child development, and postnatal vulnerability...
  5. ncbi request reprint Odorant identification and quality perception following methyl bromide-induced lesions of the olfactory epithelium
    Steven L Youngentob
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 120:1346-55. 2006
    ..These results provide strong support for the proposition that the regional variations in mucosal sensitivities within and across olfactory receptor gene expression zones are fundamentally important for the encoding of odorant quality...
  6. pmc Predicting odorant quality perceptions from multidimensional scaling of olfactory bulb glomerular activity patterns
    Steven L Youngentob
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 120:1337-45. 2006
    ..These results strongly support the relevance of global spatial patterns in the olfactory bulb to the encoding of odor quality...
  7. pmc A method for the rapid automated assessment of olfactory function
    Steven L Youngentob
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, Institute for Human Performance, 750 East Adams Street, Syracuse, NY 13210 USA
    Chem Senses 30:219-29. 2005
    ..In addition, applying epidemiologic screening principles to the observed data, we established an operational procedure for the evaluation of unknown animals...
  8. pmc Adolescent ethanol experience alters immediate and long-term behavioral responses to ethanol odor in observer and demonstrator rats
    Amber M Eade
    Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, New York, USA
    Behav Brain Funct 5:23. 2009
    ..abstract:..
  9. pmc The consequence of fetal ethanol exposure and adolescent odor re-exposure on the response to ethanol odor in adolescent and adult rats
    Amber M Eade
    Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, NY, USA
    Behav Brain Funct 5:3. 2009
    ..abstract:..
  10. pmc Ontogeny of the enhanced fetal-ethanol-induced behavioral and neurophysiologic olfactory response to ethanol odor
    Amber M Eade
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, New York, USA
    Alcohol Clin Exp Res 34:206-13. 2010
    ..Moreover, we sought to determine whether the P15 neurophysiologic effect persists, at least, to P40...
  11. pmc Gestational ethanol exposure alters the behavioral response to ethanol odor and the expression of neurotransmission genes in the olfactory bulb of adolescent rats
    Frank A Middleton
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Brain Res 1252:105-16. 2009
    ..Further, they provide insight into an important relationship between fetal exposure to ethanol, adolescent odor responsiveness to the drug and potential underlying molecular mechanisms for the odor-guided behavioral response...
  12. pmc The effect of gestational ethanol exposure on voluntary ethanol intake in early postnatal and adult rats
    Steven L Youngentob
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 121:1306-15. 2007
    ..These data add to a growing literature indicative of heightened early postnatal acceptance patterns resulting from maternal use or abuse of ethanol during pregnancy...
  13. ncbi request reprint The effect of NMDA-NR2B receptor subunit over-expression on olfactory memory task performance in the mouse
    Theresa L White
    Department of Neuroscience and Physiology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Brain Res 1021:1-7. 2004
    ..Moreover, for those functions that are NMDA-receptor-dependent, these data support the growing literature demonstrating the importance of the NR2B subunit...
  14. ncbi request reprint Adenoviral vector-mediated rescue of the OMP-null behavioral phenotype: enhancement of odorant threshold sensitivity
    Steven L Youngentob
    Department of Neuroscience and Physiology, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, NY, USA
    Behav Neurosci 118:636-42. 2004
    ..The rescue of the OMP-null behavioral phenotype further supports the hypothesis that OMP is an important component in olfactory signal amplification and/or transduction processing...
  15. pmc The relationship between PROP and ethanol preferences: an evaluation of 4 inbred mouse strains
    Theresa L White
    Department of Psychology, Le Moyne College, Syracuse, NY 13214, USA
    Chem Senses 32:847-53. 2007
    ..The absence of a relationship between PROP and ethanol indicates that the bitter quality in ethanol may be more highly related to other bitter compounds that are mediated by different genetic influences...
  16. ncbi request reprint Altered epithelial density and expansion of bulbar projections of a discrete HSP70 immunoreactive subpopulation of rat olfactory receptor neurons in reconstituting olfactory epithelium following exposure to methyl bromide
    Virginia McMillan Carr
    Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois 60208, USA
    J Comp Neurol 469:475-93. 2004
    ..Examination of archival 5-month post-MeBr lesion material indicates that altered projection patterns are maintained...
  17. ncbi request reprint Odorant receptor expression patterns are restored in lesion-recovered rat olfactory epithelium
    Carrie L Iwema
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Neurosci 24:356-69. 2004
    ..Thus, the primary sensory elements required for functional recovery of the olfactory system after damage are restored, and altered function implies the persistence of a more central failure in regeneration...
  18. ncbi request reprint Expression patterns of basic helix-loop-helix transcription factors define subsets of olfactory progenitor cells
    Glen L Manglapus
    Department of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Comp Neurol 479:216-33. 2004
    ..Moreover, expression of Hes1 marks that population of globose basal cells committed to making sustentacular cells after methyl bromide lesion...
  19. pmc Globose basal cells are required for reconstitution of olfactory epithelium after methyl bromide lesion
    Woochan Jang
    Department of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Comp Neurol 460:123-40. 2003
    ..In contrast, GLA-13(+) cells may give rise to respiratory metaplastic epithelium where GBCs are eliminated. Thus, we support the idea that a subpopulation of GBCs is the neural stem cell of the olfactory epithelium...

Research Grants14

  1. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 1999
    ..e., at the transduction level) and may provide insight into a therapeutic strategy that has implications for a variety of neurological disorders. ..
  2. In utero ethanol experience and olfactory plasticity
    STEVEN YOUNGENTOB; Fiscal Year: 2007
    ..It will also establish a chemosensory related conceptual framework of fetal exposure with broad based importance in child development and drug abuse. ..
  3. In utero ethanol experience and olfactory plasticity
    STEVEN YOUNGENTOB; Fiscal Year: 2006
    ..It will also establish a chemosensory related conceptual framework of fetal exposure with broad based importance in child development and drug abuse. ..
  4. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2003
    ..e., at the transduction level) and may provide insight into a therapeutic strategy that has implications for a variety of neurological disorders. ..
  5. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2002
    ..e., at the transduction level) and may provide insight into a therapeutic strategy that has implications for a variety of neurological disorders. ..
  6. DEVELOPING A RAPID SCREEN TO DETECT OLFACTORY MUTANTS
    STEVEN YOUNGENTOB; Fiscal Year: 2001
    ..For each phase, we will provide detailed information via a Web-based database linked to centralized resources. ..
  7. DEVELOPING A RAPID SCREEN TO DETECT OLFACTORY MUTANTS
    STEVEN YOUNGENTOB; Fiscal Year: 2000
    ..For each phase, we will provide detailed information via a Web-based database linked to centralized resources. ..
  8. DEVELOPING A RAPID SCREEN TO DETECT OLFACTORY MUTANTS
    STEVEN YOUNGENTOB; Fiscal Year: 1999
    ..For each phase, we will provide detailed information via a Web-based database linked to centralized resources. ..
  9. In utero ethanol experience and olfactory plasticity
    Steven L Youngentob; Fiscal Year: 2010
    ..It will also establish a chemosensory related conceptual framework of fetal exposure with broad based importance in child development and drug abuse. ..
  10. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2001
    ..e., at the transduction level) and may provide insight into a therapeutic strategy that has implications for a variety of neurological disorders. ..
  11. In utero ethanol experience and olfactory plasticity
    STEVEN YOUNGENTOB; Fiscal Year: 2005
    ..It will also establish a chemosensory related conceptual framework of fetal exposure with broad based importance in child development and drug abuse. ..
  12. BEHAVIORAL ANALYSIS OF OMPS ROLE IN ODOR PROCESSING
    STEVEN YOUNGENTOB; Fiscal Year: 2000
    ..e., at the transduction level) and may provide insight into a therapeutic strategy that has implications for a variety of neurological disorders. ..
  13. In utero ethanol experience and olfactory plasticity
    STEVEN YOUNGENTOB; Fiscal Year: 2009
    ..It will also establish a chemosensory related conceptual framework of fetal exposure with broad based importance in child development and drug abuse. ..