Research Topics
Species | D M GilbertSummaryAffiliation: SUNY Upstate Medical University Country: USA Publications
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Detail Information
Publications
Making sense of eukaryotic DNA replication originsD M Gilbert
Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
Science 294:96-100. 2001..Viewed in this context, the locations of origins may be an integral part of the functional organization of eukaryotic chromosomes...
Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complexD S Dimitrova
Department of Biochemistry and Molecular Biology, S U N Y Health Science Center, Syracuse, New York 13210, USA
J Cell Biol 146:709-22. 1999..During S-phase, RPA was present with PCNA specifically at active replication forks. Together, our data are consistent with a role for Mcm proteins, but not RPA, in the formation of mammalian pre-RCs during early G1-phase...
The replication timing program of the Chinese hamster beta-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phaseF Li
Department of Biochemistry and Molecular Biology, State University of New York Upstate Medical University, Syracuse, NY 13210, USA
J Cell Biol 154:283-92. 2001..These results suggest that the CHO beta-globin locus acquires the replication timing program of peripheral heterochromatin upon association with the peripheral subnuclear compartment during early G1 phase...
Stability and nuclear distribution of mammalian replication protein A heterotrimeric complexD S Dimitrova
Department of Biochemistry and Molecular Biology, State University of New York Health Sciences Center, 750 East Adams Street, Syracuse, New York 13210, USA
Exp Cell Res 254:321-7. 2000..Our results are consistent with a role for RPA in the initiation and elongation steps of replication, as previously defined in the viral in vitro replication systems...
Replication origins in yeast versus metazoa: separation of the haves and the have notsD M Gilbert
Department of Biochemistry and Molecular Biology, SUNY Health Science Center, Syracuse 13210, USA
Curr Opin Genet Dev 8:194-9. 1998..These observations suggest that initiation of DNA replication in higher eukaryotes is focused to specific genomic regions by features of chromosome structure...
Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycleY Okuno
Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
EMBO J 20:4263-77. 2001..A subsequent, as yet undefined, step selects which pre-RCs will function as replication origins...
