J B Domachowske

Summary

Affiliation: SUNY Upstate Medical University
Country: USA

Publications

  1. pmc A randomized trial of candidate inactivated quadrivalent influenza vaccine versus trivalent influenza vaccines in children aged 3-17 years
    Joseph B Domachowske
    Department of Pediatrics, Golisano Children s Hospital, Upstate Medical University, Syracuse, New York 13210, USA
    J Infect Dis 207:1878-87. 2013
  2. doi request reprint A randomized, controlled trial in children to assess the immunogenicity and safety of a thimerosal-free trivalent seasonal influenza vaccine
    Joseph B Domachowske
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Pediatr Infect Dis J 31:605-15. 2012
  3. pmc Inflammatory responses to acute pneumovirus infection in neonatal mice
    Cynthia A Bonville
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY, USA
    Virol J 7:320. 2010
  4. pmc Efficient replication of pneumonia virus of mice (PVM) in a mouse macrophage cell line
    Kimberly D Dyer
    Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Virol J 4:48. 2007
  5. pmc Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice
    Jessica S Siegle
    Department of Pathology, University of New South Wales, Sydney, NSW, Australia
    Respir Res 11:14. 2010
  6. pmc Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo
    Cynthia A Bonville
    SUNY Upstate Medical University, Syracuse, New York 13210, USA
    BMC Immunol 10:14. 2009
  7. ncbi request reprint Glucocorticoid administration accelerates mortality of pneumovirus-infected mice
    J B Domachowske
    Department of Pediatrics, Division of Infectious Diseases, State University of New York Upstate Medical University, Syracuse, NY, USA
    J Infect Dis 184:1518-23. 2001
  8. pmc Gene expression in epithelial cells in response to pneumovirus infection
    J B Domachowske
    State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    Respir Res 2:225-33. 2001
  9. ncbi request reprint Differential expression of proinflammatory cytokine genes in vivo in response to pathogenic and nonpathogenic pneumovirus infections
    Joseph B Domachowske
    Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, NY 13210, USA
    J Infect Dis 186:8-14. 2002
  10. ncbi request reprint Cytokeratin 17 is expressed in cells infected with respiratory syncytial virus via NF-kappaB activation and is associated with the formation of cytopathic syncytia
    J B Domachowske
    Department of Pediatrics, Division of Infectious Disease, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    J Infect Dis 182:1022-8. 2000

Collaborators

Detail Information

Publications32

  1. pmc A randomized trial of candidate inactivated quadrivalent influenza vaccine versus trivalent influenza vaccines in children aged 3-17 years
    Joseph B Domachowske
    Department of Pediatrics, Golisano Children s Hospital, Upstate Medical University, Syracuse, New York 13210, USA
    J Infect Dis 207:1878-87. 2013
    ..We assessed a candidate inactivated quadrivalent influenza vaccine (QIV) containing both B lineages vs TIV in healthy children aged 3-17 years...
  2. doi request reprint A randomized, controlled trial in children to assess the immunogenicity and safety of a thimerosal-free trivalent seasonal influenza vaccine
    Joseph B Domachowske
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Pediatr Infect Dis J 31:605-15. 2012
    ..Children are at high risk of acquiring and transmitting influenza infection and are a high priority group for influenza vaccination...
  3. pmc Inflammatory responses to acute pneumovirus infection in neonatal mice
    Cynthia A Bonville
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY, USA
    Virol J 7:320. 2010
    ....
  4. pmc Efficient replication of pneumonia virus of mice (PVM) in a mouse macrophage cell line
    Kimberly D Dyer
    Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Virol J 4:48. 2007
    ....
  5. pmc Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice
    Jessica S Siegle
    Department of Pathology, University of New South Wales, Sydney, NSW, Australia
    Respir Res 11:14. 2010
    ..The purpose of this study was to assess whether early-life infection with a species-specific model of RSV and subsequent allergen exposure predisposed to the development of features of asthma...
  6. pmc Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo
    Cynthia A Bonville
    SUNY Upstate Medical University, Syracuse, New York 13210, USA
    BMC Immunol 10:14. 2009
    ....
  7. ncbi request reprint Glucocorticoid administration accelerates mortality of pneumovirus-infected mice
    J B Domachowske
    Department of Pediatrics, Division of Infectious Diseases, State University of New York Upstate Medical University, Syracuse, NY, USA
    J Infect Dis 184:1518-23. 2001
    ..These results suggest several mechanisms to explain why glucocorticoid therapy may be of limited benefit in the overall picture of pneumovirus infection...
  8. pmc Gene expression in epithelial cells in response to pneumovirus infection
    J B Domachowske
    State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    Respir Res 2:225-33. 2001
    ....
  9. ncbi request reprint Differential expression of proinflammatory cytokine genes in vivo in response to pathogenic and nonpathogenic pneumovirus infections
    Joseph B Domachowske
    Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, NY 13210, USA
    J Infect Dis 186:8-14. 2002
    ....
  10. ncbi request reprint Cytokeratin 17 is expressed in cells infected with respiratory syncytial virus via NF-kappaB activation and is associated with the formation of cytopathic syncytia
    J B Domachowske
    Department of Pediatrics, Division of Infectious Disease, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    J Infect Dis 182:1022-8. 2000
    ..These results suggest that RSV-induced transcriptional activation of the Ck-17 gene is dependent on an NF-kappaB-associated signaling pathway...
  11. ncbi request reprint MIP-1alpha is produced but it does not control pulmonary inflammation in response to respiratory syncytial virus infection in mice
    J B Domachowske
    Department of Pediatrics, State University of New York Upstate Medical Center, Syracuse, New York 13210, USA
    Cell Immunol 206:1-6. 2000
    ....
  12. ncbi request reprint Epithelial cells infected with respiratory syncytial virus are resistant to the anti-inflammatory effects of hydrocortisone
    C A Bonville
    Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, New York, 13210, USA
    Cell Immunol 213:134-40. 2001
    ....
  13. ncbi request reprint Respiratory syncytial virus infection induces expression of the anti-apoptosis gene IEX-1L in human respiratory epithelial cells
    J B Domachowske
    Department of Pediatrics, Division of Infectious Disease, Upstate Medical University, Syracuse, NY 13210, USA
    J Infect Dis 181:824-30. 2000
    ..4% of control cells but only 5% of RSV-infected cells. These data show that RSV infection protects epithelial cells from TNF-alpha-induced apoptosis and that this effect is temporally associated with IEX-1L gene expression...
  14. ncbi request reprint The chemokine macrophage-inflammatory protein-1 alpha and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection
    J B Domachowske
    Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, NY, USA
    J Immunol 165:2677-82. 2000
    ..These results suggest that the MIP-1 alpha/CCR1-mediated acute inflammatory response protects mice by delaying the lethal sequelae of infection...
  15. pmc Respiratory syncytial virus infection: immune response, immunopathogenesis, and treatment
    J B Domachowske
    State University of New York Health Science Center at Syracuse, Syracuse, New York 13210
    Clin Microbiol Rev 12:298-309. 1999
    ..Although the treatment of RSV bronchiolitis is primarily supportive, the role of ribavirin is briefly discussed. Novel approaches to the development of new antiviral drugs with promising anti-RSV activity in vitro are also described...
  16. ncbi request reprint Acute manifestations and neurologic sequelae of Epstein-Barr virus encephalitis in children
    J B Domachowske
    Department of Pediatrics, State University of New York, Health Science Center at Syracuse, USA
    Pediatr Infect Dis J 15:871-5. 1996
    ..In general encephalitis caused by EBV in pediatric patients has been considered a self-limited illness with few or no sequelae...
  17. pmc First case report of catheter-related bacteremia due to "Mycobacterium lacticola"
    Deanna L Kiska
    SUNY Upstate Medical University, Department of Pathology, 750 East Adams St, Syracuse, NY 13210, USA
    J Clin Microbiol 42:2855-7. 2004
    ..The clinical relevance of this isolate, coupled with its unique 16S rRNA gene sequence, should prompt further investigation to establish this organism as a valid mycobacterial species...
  18. pmc Altered pathogenesis of severe pneumovirus infection in response to combined antiviral and specific immunomodulatory agents
    Cynthia A Bonville
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    J Virol 77:1237-44. 2003
    ....
  19. ncbi request reprint Diminished expression of an antiviral ribonuclease in response to pneumovirus infection in vivo
    Joanne M Moreau
    Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11N104, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Antiviral Res 59:181-91. 2003
    ..We propose that this mechanism may represent a novel virus-mediated evasion strategy, with a mechanism that is linked in some fashion to virus-specific pathogenicity...
  20. ncbi request reprint Diminished inflammatory responses to natural pneumovirus infection among older mice
    Cynthia A Bonville
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Virology 368:182-90. 2007
    ....
  21. pmc Functional antagonism of chemokine receptor CCR1 reduces mortality in acute pneumovirus infection in vivo
    Cynthia A Bonville
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    J Virol 78:7984-9. 2004
    ....
  22. pmc Mucosal inoculation with an attenuated mouse pneumovirus strain protects against virulent challenge in wild type and interferon-gamma receptor deficient mice
    John A Ellis
    Western Veterinary Medical College, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Vaccine 25:1085-95. 2007
    ....
  23. ncbi request reprint Mazzotti reaction after presumptive treatment for schistosomiasis and strongyloidiasis in a Liberian refugee
    Bradley G Olson
    State University of New York, Upstate Medical University, Syracuse 13210, USA
    Pediatr Infect Dis J 25:466-8. 2006
    ..The patient was hospitalized with fever, urticaria, abdominal pain and angioedema. Twelve hours after treatment with intravenous methylprednisolone he had complete resolution of his symptoms...
  24. ncbi request reprint Respiratory dysfunction and proinflammatory chemokines in the pneumonia virus of mice (PVM) model of viral bronchiolitis
    Cynthia A Bonville
    SUNY Upstate Medical University, Syracuse, NY 13210 2375, USA
    Virology 349:87-95. 2006
    ....
  25. ncbi request reprint Ribavirin and cysteinyl leukotriene-1 receptor blockade as treatment for severe bronchiolitis
    Cynthia A Bonville
    Department of Pediatrics, State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA
    Antiviral Res 69:53-9. 2006
    ..01). These findings define further the independent contributions made by virus replication and by the ensuing inflammatory response to the detrimental sequelae of pneumovirus infection in vivo...
  26. ncbi request reprint Inflammatory responses to pneumovirus infection in IFN-alpha beta R gene-deleted mice
    Tara L Garvey
    Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 175:4735-44. 2005
    ....
  27. pmc Pneumonia virus of mice: severe respiratory infection in a natural host
    Helene F Rosenberg
    Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA
    Immunol Lett 118:6-12. 2008
    ....
  28. ncbi request reprint The pneumonia virus of mice infection model for severe respiratory syncytial virus infection: identifying novel targets for therapeutic intervention
    Helene F Rosenberg
    Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Pharmacol Ther 105:1-6. 2005
    ..Ongoing exploration into the biology of PVM infection will identify other pathways and targets to be exploited for immunomodulatory control of hRSV and related severe respiratory virus infections...
  29. ncbi request reprint Animal models for studying respiratory syncytial virus infection and its long term effects on lung function
    Joseph B Domachowske
    Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, NY, USA
    Pediatr Infect Dis J 23:S228-34. 2004
    ..Human studies on the pathogenesis of RSV infection are invaluable, but animal models permit advances with the use of experimental strategies that would be inappropriate in human studies...
  30. ncbi request reprint Replication of respiratory syncytial virus is inhibited in target cells generating nitric oxide in situ
    Dania Ali-Ahmad
    Department of Pediatrics, Division of Infectious Diseases, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    Front Biosci 8:a48-53. 2003
    ....
  31. ncbi request reprint Pulmonary eosinophilia in mice devoid of interleukin-5
    Joseph B Domachowske
    Department of Pediatrics, SUNY Upstate Medical University, Syracuse, New York, USA
    J Leukoc Biol 71:966-72. 2002
    ..Furthermore, the presence of functional eosinophils in IL-5 -/- mice suggests the possibility of developmentally distinct subsets of what has been presumed to be a homogeneous leukocyte population...
  32. ncbi request reprint Gene microarray analysis reveals interleukin-5-dependent transcriptional targets in mouse bone marrow
    Jonas Bystrom
    NIAID, NIH, Bldg 10, Rm 11N104, 9000 Rockville Pike, Bethesda, MD, 20892, USA
    Blood 103:868-77. 2004
    ....