Scott D Blystone

Summary

Affiliation: SUNY Upstate Medical University
Country: USA

Publications

  1. ncbi request reprint Ligand-dependent activation of integrin alpha vbeta 3
    Boyd Butler
    Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 278:5264-70. 2003
  2. ncbi request reprint Kinetic regulation of beta 3 integrin tyrosine phosphorylation
    Scott D Blystone
    Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 277:46886-90. 2002
  3. ncbi request reprint Tyrosine phosphorylation of beta3 integrin provides a binding site for Pyk2
    Boyd Butler
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 280:14556-62. 2005
  4. ncbi request reprint Integrating an integrin: a direct route to actin
    Scott D Blystone
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Biochim Biophys Acta 1692:47-54. 2004
  5. ncbi request reprint Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes
    Chunlei Gao
    Department of Cell and Development Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 280:15422-9. 2005
  6. ncbi request reprint Integrin alphaIIb-subunit cytoplasmic domain mutations demonstrate a requirement for tyrosine phosphorylation of beta3-subunits in actin cytoskeletal organization
    Innocent H Yamodo
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    Cell Commun Adhes 11:121-35. 2004
  7. doi request reprint A Pyk2-Vav1 complex is recruited to beta3-adhesion sites to initiate Rho activation
    Chunlei Gao
    Department of Cell and Development Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Biochem J 420:49-56. 2009
  8. ncbi request reprint Purified integrin adhesion complexes exhibit actin-polymerization activity
    Boyd Butler
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, 750 East Adams St, Syracuse, New York 13210, USA
    Curr Biol 16:242-51. 2006
  9. ncbi request reprint Beta 3 integrin phosphorylation is essential for Arp3 organization into leukocyte alpha V beta 3-vitronectin adhesion contacts
    Surjit K Chandhoke
    Department of Cell and Developmental Biology SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY 13210, USA
    J Cell Sci 117:1431-41. 2004
  10. pmc The formin FRL1 (FMNL1) is an essential component of macrophage podosomes
    Akos T Mersich
    Department of Cell and Development Biology, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    Cytoskeleton (Hoboken) 67:573-85. 2010

Collaborators

  • Jason A Horton
  • Errol Wijelath
  • Boyd Butler
  • Akos T Mersich
  • Chunlei Gao
  • Elisabeth C Krainer
  • Matthew R Miller
  • George P Christophi
  • Erik Schaefer
  • Surjit K Chandhoke
  • Innocent H Yamodo
  • Monica S Da Silva
  • Eric W Miller
  • Jessica L Ouderkirk
  • Halina Chkourko
  • Rebecca L Christophi
  • Burk Jubelt
  • Ross C Gruber
  • Chad A Hudson
  • Michael Panos
  • Paul T Massa
  • Montaha Lakkis
  • Matthew Williams
  • Linda Zorn
  • Lisa W Blystone
  • Jacqui M Wijelath
  • Michael Sobel
  • Kurt Strand
  • Wallace R Fish

Detail Information

Publications13

  1. ncbi request reprint Ligand-dependent activation of integrin alpha vbeta 3
    Boyd Butler
    Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 278:5264-70. 2003
    ....
  2. ncbi request reprint Kinetic regulation of beta 3 integrin tyrosine phosphorylation
    Scott D Blystone
    Department of Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 277:46886-90. 2002
    ..These data demonstrate that recognition of ligand is sufficient to induce beta(3) tyrosine phosphorylation and suggests that this event is regulated by the alpha subunit pairing of beta(3)...
  3. ncbi request reprint Tyrosine phosphorylation of beta3 integrin provides a binding site for Pyk2
    Boyd Butler
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 280:14556-62. 2005
    ..These data identify Pyk2 as a phosphorylated beta(3) binding partner, providing a potential structural and signaling platform to achieve alpha(V)beta(3) -mediated remodeling of the actin cytoskeleton...
  4. ncbi request reprint Integrating an integrin: a direct route to actin
    Scott D Blystone
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Biochim Biophys Acta 1692:47-54. 2004
    ....
  5. ncbi request reprint Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes
    Chunlei Gao
    Department of Cell and Development Biology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
    J Biol Chem 280:15422-9. 2005
    ..These studies describe a phosphorylation-dependent association between beta(3) integrin and Vav1 which is essential for cell progression to a Rho-dominant phenotype during cell adhesion...
  6. ncbi request reprint Integrin alphaIIb-subunit cytoplasmic domain mutations demonstrate a requirement for tyrosine phosphorylation of beta3-subunits in actin cytoskeletal organization
    Innocent H Yamodo
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    Cell Commun Adhes 11:121-35. 2004
    ....
  7. doi request reprint A Pyk2-Vav1 complex is recruited to beta3-adhesion sites to initiate Rho activation
    Chunlei Gao
    Department of Cell and Development Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Biochem J 420:49-56. 2009
    ..These results indicate that Pyk2 is a critical signalling molecule downstream of beta3 integrin tyrosine phosphorylation and mediates Vav1 recruitment to accomplish actin reorganization necessary for adhesion...
  8. ncbi request reprint Purified integrin adhesion complexes exhibit actin-polymerization activity
    Boyd Butler
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, 750 East Adams St, Syracuse, New York 13210, USA
    Curr Biol 16:242-51. 2006
    ..To determine whether this linkage is attained actively or passively, we isolated integrin complexes from nonadherent hematopoietic cells and determined their influence on the polymerization of actin...
  9. ncbi request reprint Beta 3 integrin phosphorylation is essential for Arp3 organization into leukocyte alpha V beta 3-vitronectin adhesion contacts
    Surjit K Chandhoke
    Department of Cell and Developmental Biology SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY 13210, USA
    J Cell Sci 117:1431-41. 2004
    ....
  10. pmc The formin FRL1 (FMNL1) is an essential component of macrophage podosomes
    Akos T Mersich
    Department of Cell and Development Biology, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    Cytoskeleton (Hoboken) 67:573-85. 2010
    ..Our data suggest that FRL1 is responsible for modifying actin at the macrophage podosome and may be involved in actin cytoskeleton dynamics during adhesion and migration within tissues...
  11. pmc The multiplicity of human formins: Expression patterns in cells and tissues
    Elisabeth C Krainer
    Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York, 13210
    Cytoskeleton (Hoboken) 70:424-38. 2013
    ..Identification of major themes in formin expression and documentation of expression profiles should facilitate the cellular study of formins...
  12. ncbi request reprint Heparin modulates integrin-mediated cellular adhesion: specificity of interactions with alpha and beta integrin subunits
    Monica S Da Silva
    Department of Surgery, SUNY Upstate Medical University and Veteran Affairs Medical Center, Syracuse, NY, USA
    Cell Commun Adhes 10:59-67. 2003
    ..The inhibitory or stimulatory effects of heparin depend on the beta subunit type, and the potency is dictated by structural characteristics of the glycosaminoglycan...
  13. pmc Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype
    George P Christophi
    Department of Neurology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Lab Invest 89:742-59. 2009
    ....