Research Topics
Genomes and GenesSpecies | Scott L PageSummaryAffiliation: Stowers Institute for Medical Research Country: USA Publications
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Publications
Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila oocytesScott L Page
Comparative Genomics Centre, School of Pharmacy and Molecular Sciences, James Cook University, Townsville, Australia
PLoS Genet 4:e1000194. 2008....- The Drosophila meiotic mutant mei-352 is an allele of klp3A and reveals a role for a kinesin-like protein in crossover distributionScott L Page
Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA
Genetics 170:1797-807. 2005.... 
The genetics and molecular biology of the synaptonemal complexScott L Page
Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA
Annu Rev Cell Dev Biol 20:525-58. 2004..Finally, in at least some organisms, modifications of the SC alone are sufficient to ensure meiotic chromosome segregation in the complete absence of meiotic recombination...- A germline clone screen for meiotic mutants in Drosophila melanogasterScott L Page
Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA
Fly (Austin) 1:172-81. 2007..This study demonstrates the utility of germline clone-based screens for the discovery of strong meiotic mutants, including mutations in essential genes, and the use of molecular genetic techniques to map the loci... - The formation of the central element of the synaptonemal complex may occur by multiple mechanisms: the roles of the N- and C-terminal domains of the Drosophila C(3)G protein in mediating synapsis and recombinationJennifer K Jeffress
Stowers Institute for Medical Research, Kansas City, Kansas, USA
Genetics 177:2445-56. 2007.... - A genetic analysis of the Drosophila mcm5 gene defines a domain specifically required for meiotic recombinationCathleen M Lake
Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA
Genetics 176:2151-63. 2007..These results strengthen the observation that members of the prereplicative complex have multiple functions and provide evidence that mcm5 plays a critical role in the meiotic recombination pathway... - Chromosome choreography: the meiotic balletScott L Page
Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA
Science 301:785-9. 2003..Failures to properly accomplish this elegant chromosome dance result in aneuploidy, a major cause of miscarriage and birth defects in human beings... - Juxtaposition of C(2)M and the transverse filament protein C(3)G within the central region of Drosophila synaptonemal complexLorinda K Anderson
Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
Proc Natl Acad Sci U S A 102:4482-7. 2005..Based on our data and the known phenotypes of C(2)M and C(3)G mutants, we propose a model of SC structure in which C(2)M links C(3)G to the LEs... - Obligate short-arm exchange in de novo Robertsonian translocation formation influences placement of crossovers in chromosome 21 nondisjunctionSue Ann Berend
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Am J Hum Genet 72:488-95. 2003..Additionally, we have demonstrated that events that occur in meiosis I can influence events, such as chromatid segregation in meiosis II, many decades later... - The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) proteinGraham Hallson
Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada V5A 1S6
Proc Natl Acad Sci U S A 105:12405-10. 2008..e., like vtd, they act as dominant suppressors of Pc and hh(Mrt) without impairing cell division. Our results provide a framework to further investigate how cohesin and associated components might regulate transcription... - Parental origin and timing of de novo Robertsonian translocation formationRuma Bandyopadhyay
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Am J Hum Genet 71:1456-62. 2002..quot; Thus, we demonstrate that although both classes of ROBs occur predominantly during meiosis, the common, class 1 ROBs occur primarily during oogenesis and likely form through a mechanism distinct from that forming class 2 ROBs...