Jennifer Gerton

Summary

Affiliation: Stowers Institute for Medical Research
Country: USA

Publications

  1. pmc Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae
    Earl F Glynn
    Stowers Institute for Medical Research, Kansas City, Missouri, USA
    PLoS Biol 2:E259. 2004
  2. ncbi request reprint Enhancing togetherness: kinetochores and cohesion
    Jennifer L Gerton
    Stowers Institute for Medical Research, University of Kansas Medical Center, Kansas City, Missouri 64110, USA
    Genes Dev 21:238-41. 2007
  3. pmc Chromosome cohesion: a cycle of holding together and falling apart
    Jennifer Gerton
    Stowers Institute for Medical Research, Kansas City, USA
    PLoS Biol 3:e94. 2005
  4. ncbi request reprint Homologous chromosome interactions in meiosis: diversity amidst conservation
    Jennifer L Gerton
    The Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, Missouri 64110, USA
    Nat Rev Genet 6:477-87. 2005
  5. pmc Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling
    Bing Li
    Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA
    Proc Natl Acad Sci U S A 102:18385-90. 2005
  6. pmc Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast
    Jill M Henry
    The Stowers Institute for Medical Research, 1000 E 50th St, Kansas City, MO 64110, USA
    Mol Cell Biol 26:2913-23. 2006
  7. ncbi request reprint Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore
    Raymond Camahort
    The Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA
    Mol Cell 26:853-65. 2007
  8. doi request reprint The chromosome glue gets a little stickier
    Adrian J McNairn
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Trends Genet 24:382-9. 2008
  9. pmc Cohesinopathies, gene expression, and chromatin organization
    Tania Bose
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Cell Biol 189:201-10. 2010
  10. pmc The kinetochore is an enhancer of pericentric cohesin binding
    Stewart A Weber
    Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center at Fitzsimons, Aurora, Colorado, USA
    PLoS Biol 2:E260. 2004

Research Grants

Collaborators

Detail Information

Publications13

  1. pmc Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae
    Earl F Glynn
    Stowers Institute for Medical Research, Kansas City, Missouri, USA
    PLoS Biol 2:E259. 2004
    ..The genome-wide view of mitotic and meiotic cohesin binding provides an important framework for the exploration of cohesins and cohesion in other genomes...
  2. ncbi request reprint Enhancing togetherness: kinetochores and cohesion
    Jennifer L Gerton
    Stowers Institute for Medical Research, University of Kansas Medical Center, Kansas City, Missouri 64110, USA
    Genes Dev 21:238-41. 2007
  3. pmc Chromosome cohesion: a cycle of holding together and falling apart
    Jennifer Gerton
    Stowers Institute for Medical Research, Kansas City, USA
    PLoS Biol 3:e94. 2005
  4. ncbi request reprint Homologous chromosome interactions in meiosis: diversity amidst conservation
    Jennifer L Gerton
    The Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, Missouri 64110, USA
    Nat Rev Genet 6:477-87. 2005
    ..Although all organisms must match and lock homologous chromosomes to maintain genome integrity throughout meiosis, recent results indicate that the underlying mechanisms vary in different organisms...
  5. pmc Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling
    Bing Li
    Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA
    Proc Natl Acad Sci U S A 102:18385-90. 2005
    ..These lines of evidence collectively suggest that Htz1 may serve to mark quiescent promoters for proper activation...
  6. pmc Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast
    Jill M Henry
    The Stowers Institute for Medical Research, 1000 E 50th St, Kansas City, MO 64110, USA
    Mol Cell Biol 26:2913-23. 2006
    ..Our results support a model in which Mnd1/Hop2 is required for DNA-DNA interactions that help ensure Dmc1-mediated stable strand invasion between homologous chromosomes, thereby preserving genomic integrity...
  7. ncbi request reprint Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore
    Raymond Camahort
    The Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA
    Mol Cell 26:853-65. 2007
    ..In addition, Scm3 is required to maintain kinetochore function throughout the cell cycle. We propose a model in which Ndc10/Scm3 binds to centromeric DNA, which is in turn essential for targeting Cse4 to centromeres...
  8. doi request reprint The chromosome glue gets a little stickier
    Adrian J McNairn
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Trends Genet 24:382-9. 2008
    ..Moreover, this newly appreciated role is necessary for proper development in metazoan species, with mutations in the cohesin pathway resulting in human developmental disorders...
  9. pmc Cohesinopathies, gene expression, and chromatin organization
    Tania Bose
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Cell Biol 189:201-10. 2010
    ..Moreover, cohesin defects compromise the subnuclear position of chromatin. Therefore, defects in the cohesin network that alter gene expression and genome organization may underlie cohesinopathies...
  10. pmc The kinetochore is an enhancer of pericentric cohesin binding
    Stewart A Weber
    Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center at Fitzsimons, Aurora, Colorado, USA
    PLoS Biol 2:E260. 2004
    ..We suggest that the coordination of chromosome movement and biorientation makes the kinetochore an autonomous segregation unit...
  11. pmc The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation
    Kimberly A Collins
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1042, USA
    Genetics 175:513-25. 2007
    ....
  12. pmc Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Biology and Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3280, USA
    Mol Cell Biol 26:1014-27. 2006
    ..These results argue that both local and regional factors affect the level of meiotic recombination...
  13. pmc Mnd1p: an evolutionarily conserved protein required for meiotic recombination
    Jennifer L Gerton
    Department of Biochemistry and Biophysics, University of California, 513 Parnassus Avenue, Box 0448, San Francisco, CA 94143 0448, USA
    Proc Natl Acad Sci U S A 99:6895-900. 2002
    ..Orthologs of MND1 were identified in protists, several yeasts, plants, and mammals, suggesting that its function has been conserved throughout evolution...

Research Grants3

  1. Molecular Mechanisms of Chromosome Segregation in Yeast
    Jennifer L Gerton; Fiscal Year: 2010
    ..Cancer Res, 2005. 65: p. 4683-9. 3. Heun, P., et al., Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores. Dev Cell, 2006. 10: p. 303-15. ..