Marco Blanchette

Summary

Affiliation: Stowers Institute for Medical Research
Country: USA

Publications

  1. ncbi Genome-wide analysis of alternative pre-mRNA splicing and RNA-binding specificities of the Drosophila hnRNP A/B family members
    Marco Blanchette
    Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 33:438-49. 2009
  2. ncbi Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells
    Britta Hartmann
    Centre de Regulacio Genomica, Parc de Recerca Biomedica de Barcelona, Dr Aiguader 88, Barcelona, Spain
    Genome Biol 10:R11. 2009
  3. ncbi Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs
    Marco Blanchette
    Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 14:775-86. 2004
  4. ncbi Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression
    J Matthew Taliaferro
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Genes Dev 27:378-89. 2013
  5. ncbi Evolution of a tissue-specific splicing network
    J Matthew Taliaferro
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Genes Dev 25:608-20. 2011
  6. ncbi Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila
    Marco Blanchette
    Department of Molecular and Cell Biology, Center for Integrative Genomics, Plant and Microbial Biology, University of California, Berkeley, 94720 3204 USA
    Genes Dev 19:1306-14. 2005
  7. ncbi Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila
    Kasper Daniel Hansen
    Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, CA, USA
    PLoS Genet 5:e1000525. 2009
  8. ncbi Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes
    Richard E Green
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Bioinformatics 19:i118-21. 2003
  9. ncbi An SF1 affinity model to identify branch point sequences in human introns
    Alexander W Pastuszak
    Department of Biochemistry and Biophysics, University of California, San Francisco, USA
    Nucleic Acids Res 39:2344-56. 2011
  10. ncbi CDK phosphorylation inhibits the DNA-binding and ATP-hydrolysis activities of the Drosophila origin recognition complex
    Dirk Remus
    Department of Molecular and Cell Biology, Division of Biochemistry and Molecular Biology, University of California, Berkeley, California 94720 3204, USA
    J Biol Chem 280:39740-51. 2005

Collaborators

  • Richard E Green
  • Elisa Izaurralde
  • Donald C Rio
  • J Matthew Taliaferro
  • Alexander W Pastuszak
  • Steven E Brenner
  • Britta Hartmann
  • Kasper Daniel Hansen
  • Dirk Remus
  • Emmanuel Labourier
  • Dhruv Marwha
  • Todd Bradley
  • Julie L Aspden
  • Nehemiah Alvarez
  • Marcin P Joachimiak
  • Alan D Frankel
  • Juan Valcarcel
  • Fabian L Gallusser
  • Robert Castelo
  • Stephanie Boue
  • Sandrine Dudoit
  • Jan Rehwinkel
  • Qi Meng
  • Liana F Lareau
  • Michael R Botchan
  • Melissa D Adams
  • Jennie W Feiger

Detail Information

Publications11

  1. ncbi Genome-wide analysis of alternative pre-mRNA splicing and RNA-binding specificities of the Drosophila hnRNP A/B family members
    Marco Blanchette
    Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 33:438-49. 2009
    ..These results indicate that individual heterogeneous ribonucleoproteins have specific affinities for overlapping, but distinct, populations of target pre-mRNAs controlling their patterns of RNA processing...
  2. ncbi Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells
    Britta Hartmann
    Centre de Regulacio Genomica, Parc de Recerca Biomedica de Barcelona, Dr Aiguader 88, Barcelona, Spain
    Genome Biol 10:R11. 2009
    ..We report a genome-wide analysis using splicing-sensitive microarrays of changes in alternative splicing induced by activation of two distinct signaling pathways, insulin and wingless, in Drosophila cells in culture...
  3. ncbi Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs
    Marco Blanchette
    Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 14:775-86. 2004
    ..Immunopurification of nuclear RNP complexes showed that dU2AF50 associates with intronless mRNAs. These results reveal an unexpected role for the splicing factor dU2AF50 in the nuclear export of intronless mRNAs...
  4. ncbi Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression
    J Matthew Taliaferro
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Genes Dev 27:378-89. 2013
    ..These results suggest two new nuclear roles for Ago-2: one in pre-mRNA splicing and one in transcriptional repression...
  5. ncbi Evolution of a tissue-specific splicing network
    J Matthew Taliaferro
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Genes Dev 25:608-20. 2011
    ..We therefore propose a path for the evolution of a new splicing factor in Drosophila that regulates specific pre-mRNAs and contributes to transcript diversity in a tissue-specific manner...
  6. ncbi Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila
    Marco Blanchette
    Department of Molecular and Cell Biology, Center for Integrative Genomics, Plant and Microbial Biology, University of California, Berkeley, 94720 3204 USA
    Genes Dev 19:1306-14. 2005
    ....
  7. ncbi Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila
    Kasper Daniel Hansen
    Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, CA, USA
    PLoS Genet 5:e1000525. 2009
    ..Most notably, we found that the NMD-target mRNAs had significantly longer 3' untranslated regions (UTRs) than the nontarget isoforms of the same genes, supporting a role for 3' UTR length in the recognition of NMD targets in fly...
  8. ncbi Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes
    Richard E Green
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Bioinformatics 19:i118-21. 2003
    ..Our initial experimental studies are consistent with these predictions and suggest an unappreciated role for NMD in several human diseases...
  9. ncbi An SF1 affinity model to identify branch point sequences in human introns
    Alexander W Pastuszak
    Department of Biochemistry and Biophysics, University of California, San Francisco, USA
    Nucleic Acids Res 39:2344-56. 2011
    ..The combined model, together with binding site location constraints, accurately identified introns bound by SF1 that are candidates for SF1-dependent splicing...
  10. ncbi CDK phosphorylation inhibits the DNA-binding and ATP-hydrolysis activities of the Drosophila origin recognition complex
    Dirk Remus
    Department of Molecular and Cell Biology, Division of Biochemistry and Molecular Biology, University of California, Berkeley, California 94720 3204, USA
    J Biol Chem 280:39740-51. 2005
    ..These results suggest molecular mechanisms by which Cdks may inhibit ORC function as part of re-replication control and show that DmORC activity may be modulated in response to phosphorylation by multiple kinases...
  11. ncbi The KH-type RNA-binding protein PSI is required for Drosophila viability, male fertility, and cellular mRNA processing
    Emmanuel Labourier
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Genes Dev 16:72-84. 2002
    ..These results also validate the use of cDNA microarrays to characterize in vivo RNA-processing defects and alternative pre-mRNA splicing patterns...