Aaron M Neiman

Summary

Affiliation: Stony Brook University
Country: USA

Publications

  1. pmc A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae
    Coney Pei Chen Lin
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
    PLoS Genet 9:e1003700. 2013
  2. pmc Sporulation in the budding yeast Saccharomyces cerevisiae
    Aaron M Neiman
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794 5215, USA
    Genetics 189:737-65. 2011
  3. pmc Vesicle docking to the spindle pole body is necessary to recruit the exocyst during membrane formation in Saccharomyces cerevisiae
    Erin M Mathieson
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    Mol Biol Cell 21:3693-707. 2010
  4. pmc Membrane assembly modulates the stability of the meiotic spindle-pole body
    Erin M Mathieson
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    J Cell Sci 123:2481-90. 2010
  5. pmc Soft X-ray diffraction microscopy of a frozen hydrated yeast cell
    Xiaojing Huang
    Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York 11794 3800, USA
    Phys Rev Lett 103:198101. 2009
  6. pmc A screen for spore wall permeability mutants identifies a secreted protease required for proper spore wall assembly
    Yasuyuki Suda
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
    PLoS ONE 4:e7184. 2009
  7. pmc Regulation of spindle pole function by an intermediary metabolite
    Mark E Nickas
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Mol Biol Cell 15:2606-16. 2004
  8. pmc Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae
    Mark E Nickas
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Eukaryot Cell 2:431-45. 2003
  9. ncbi request reprint Phospholipase D and the SNARE Sso1p are necessary for vesicle fusion during sporulation in yeast
    Hideki Nakanishi
    Department of Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, NY 4 5215, USA
    J Cell Sci 119:1406-15. 2006
  10. pmc Binding interactions control SNARE specificity in vivo
    Hui Ju Yang
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794, USA
    J Cell Biol 183:1089-100. 2008

Collaborators

  • Enju Lima
  • Johanna Nelson
  • JoAnne Engebrecht
  • Yao Yu
  • Michael E Dresser
  • Pierre Thibault
  • Rolf Sternglanz
  • Jan Steinbrener
  • Hideki Nakanishi
  • Jae Sook Park
  • Yasuyuki Suda
  • Alison Coluccio
  • Erin M Mathieson
  • Mark E Nickas
  • Hui Ju Yang
  • Alison E Coluccio
  • Song Liu
  • Aviva E Diamond
  • David Shapiro
  • Chien Lam
  • Carey Kim
  • Coney Pei Chen Lin
  • Hiroyuki Tachikawa
  • Huei Mei Chen
  • Xiaojing Huang
  • Rachael K Rodriguez
  • James A McNew
  • Chris Jacobsen
  • Huijie Miao
  • Janos Kirz
  • Cindi Schwartz
  • Leor Needleman
  • Ethan Santore
  • Elizabeth Lavoie
  • Nicholas Fiacco
  • Yuuya Okumura
  • Steven O Smith
  • Mark Nickas
  • Eric G D Muller
  • Trisha N Davis
  • Brian Snydsman
  • Ichiro Inoue
  • Stefano Marchesini
  • Joshua J Turner
  • Andrew Stewart
  • Maurice J Kernan
  • Travis Rice-Stitt
  • Kirilee A Wilson
  • Cindi L Schwartz
  • Masayo Morishita
  • Veit Elser
  • Tobias Beetz
  • Malcolm Howells
  • David Sayre
  • Michael N Conrad
  • Edith Bogengruber
  • Maria Malzone
  • Peter Briza
  • Pablo de los Santos
  • Min Jay Yang

Detail Information

Publications29

  1. pmc A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae
    Coney Pei Chen Lin
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
    PLoS Genet 9:e1003700. 2013
    ..Localization of gene products identified in the screen reveals an unexpected role for lipid droplets in outer spore wall formation. ..
  2. pmc Sporulation in the budding yeast Saccharomyces cerevisiae
    Aaron M Neiman
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794 5215, USA
    Genetics 189:737-65. 2011
    ..Key regulatory points on the sporulation pathway are also discussed as well as the possible role of sporulation in the natural ecology of S. cerevisiae...
  3. pmc Vesicle docking to the spindle pole body is necessary to recruit the exocyst during membrane formation in Saccharomyces cerevisiae
    Erin M Mathieson
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    Mol Biol Cell 21:3693-707. 2010
    ..This suggests that the MOP promotes membrane formation both by localization of precursor vesicles to a particular site and by recruitment of a second tethering complex, the exocyst, that stimulates downstream events of fusion...
  4. pmc Membrane assembly modulates the stability of the meiotic spindle-pole body
    Erin M Mathieson
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    J Cell Sci 123:2481-90. 2010
    ..These results suggest an architectural rearrangement of the MOP coincident with vesicle fusion...
  5. pmc Soft X-ray diffraction microscopy of a frozen hydrated yeast cell
    Xiaojing Huang
    Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York 11794 3800, USA
    Phys Rev Lett 103:198101. 2009
    ..This demonstration represents an important step towards high resolution imaging of cells in their natural, hydrated state, without limitations imposed by x-ray optics...
  6. pmc A screen for spore wall permeability mutants identifies a secreted protease required for proper spore wall assembly
    Yasuyuki Suda
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
    PLoS ONE 4:e7184. 2009
    ..OSW3 and other OSW genes identified in this screen are strong candidates to encode enzymes involved in assembly of this protective dityrosine coat...
  7. pmc Regulation of spindle pole function by an intermediary metabolite
    Mark E Nickas
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Mol Biol Cell 15:2606-16. 2004
    ..These results define a cellular response in which the accumulation of an intermediary metabolite serves as a measure of biosynthetic capacity to regulate the number of daughter cells formed...
  8. pmc Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae
    Mark E Nickas
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Eukaryot Cell 2:431-45. 2003
    ....
  9. ncbi request reprint Phospholipase D and the SNARE Sso1p are necessary for vesicle fusion during sporulation in yeast
    Hideki Nakanishi
    Department of Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, NY 4 5215, USA
    J Cell Sci 119:1406-15. 2006
    ..These results demonstrate a role for phospholipase D in vesicle fusion and suggest that phospholipase D-generated phosphatidic acid plays multiple roles in the fusion process...
  10. pmc Binding interactions control SNARE specificity in vivo
    Hui Ju Yang
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794, USA
    J Cell Biol 183:1089-100. 2008
    ..These results demonstrate that differences within the SNARE helices can discriminate between closely related SNAREs for function in vivo...
  11. pmc Alternative modes of organellar segregation during sporulation in Saccharomyces cerevisiae
    Yasuyuki Suda
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    Eukaryot Cell 6:2009-17. 2007
    ..These results reveal that organellar segregation into spores is achieved by mechanisms distinct from those in mitotic cells...
  12. pmc SPO71 encodes a developmental stage-specific partner for Vps13 in Saccharomyces cerevisiae
    Jae Sook Park
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA
    Eukaryot Cell 12:1530-7. 2013
    ..Finally, the two proteins can be coprecipitated from sporulating cells. We propose that Spo71 is a sporulation-specific partner for Vps13 and that they act in concert to regulate prospore membrane morphogenesis. ..
  13. pmc Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae
    Alison Coluccio
    Life Sciences, SUNY Stony Brook, Stony Brook, NY 11794 5215, USA
    Eukaryot Cell 3:1464-75. 2004
    ..The results demonstrate that spore wall construction involves a series of dependent steps and provide the outline of a morphogenetic pathway for assembly of a complex extracellular structure...
  14. pmc A guaninine nucleotide exchange factor is a component of the meiotic spindle pole body in Schizosaccharomyces pombe
    Hui Ju Yang
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    Mol Biol Cell 21:1272-81. 2010
    ..These results demonstrate that stimulation of Rab-GTPase activity is a property of the S. pombe MOP essential for the initiation of membrane formation...
  15. pmc The anaphase promoting complex targeting subunit Ama1 links meiotic exit to cytokinesis during sporulation in Saccharomyces cerevisiae
    Aviva E Diamond
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    Mol Biol Cell 20:134-45. 2009
    ..These results demonstrate that APC(Ama1) functions to coordinate the exit from meiosis II with cytokinesis...
  16. ncbi request reprint In vitro fusion catalyzed by the sporulation-specific t-SNARE light-chain Spo20p is stimulated by phosphatidic acid
    Song Liu
    Department of Biochemistry and Cell Biology, Rice University, 6100 Main Street MS 140, Houston, TX 77251 1892, USA
    Traffic 8:1630-43. 2007
    ..Our results suggest that the fusion strength of SNAREs, the composition of organelle lipids and lipid-SNARE interactions may be coordinately regulated to control the rate and specificity of membrane fusion...
  17. ncbi request reprint Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae
    Hideki Nakanishi
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, SUNY Stony Brook, Stony Brook, NY 11794 5215, USA
    J Cell Sci 120:908-16. 2007
    ..These results reveal a developmentally regulated change in the requirements for ER export in S. cerevisiae...
  18. pmc Genetic evidence of a role for membrane lipid composition in the regulation of soluble NEM-sensitive factor receptor function in Saccharomyces cerevisiae
    Alison Coluccio
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York, Stony Brook, New York 11794 5215, USA
    Genetics 166:89-97. 2004
    ..These results indicate that elevated levels of phosphatidic acid in the membrane may be required specifically for the function of SNARE complexes containing Spo20p...
  19. pmc High-resolution x-ray diffraction microscopy of specifically labeled yeast cells
    Johanna Nelson
    Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794 3800, USA
    Proc Natl Acad Sci U S A 107:7235-9. 2010
    ..Cells were plunge-frozen in liquid ethane and freeze-dried, after which they were imaged whole using x-ray diffraction microscopy at 750 eV photon energy...
  20. pmc Positive and negative regulation of a SNARE protein by control of intracellular localization
    Hideki Nakanishi
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, SUNY Stony Brook, Stony Brook, New York 11794 5215, USA
    Mol Biol Cell 15:1802-15. 2004
    ..Thus, the SNARE Spo20p is both positively and negatively regulated by control of its intracellular localization...
  21. pmc VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae
    Jae Sook Park
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794 5215, USA
    J Cell Sci 125:3004-11. 2012
    ..These results demonstrate that Vps13 plays a broader role in membrane biology than previously known, which could have important implications for the functions of VPS13 orthologs in humans...
  22. ncbi request reprint Interspore bridges: a new feature of the Saccharomyces cerevisiae spore wall
    Alison Coluccio
    Department of Biochemistry and Cell Biology, Institute for Cell and Developmental Biology, State University of New York, Stony Brook, 332 Life Sciences, Stony Brook, NY 11794 5215, USA
    Microbiology 150:3189-96. 2004
    ..Interspore bridges are shown to be necessary to hold spores together after release from the ascus. A function for these bridges in the maintenance of heterozygous markers in a homothallic yeast population is proposed...
  23. pmc Ascospore formation in the yeast Saccharomyces cerevisiae
    Aaron M Neiman
    Department of Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, New York 11794 5215, USA
    Microbiol Mol Biol Rev 69:565-84. 2005
    ..This review focuses on our current understanding of the cellular rearrangements and the genes required in each of these phases to give rise to a wild-type spore...
  24. pmc The JmjC domain of Gis1 is dispensable for transcriptional activation
    Yao Yu
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794 5215, USA
    FEMS Yeast Res 10:793-801. 2010
    ..Moreover, the JmjC domain is not required for the toxicity associated with Gis1 overexpression. The data demonstrate that the JmjC domain is dispensable for transcriptional activation by Gis1 during nutrient stress and sporulation...
  25. pmc The yeast spore wall enables spores to survive passage through the digestive tract of Drosophila
    Alison E Coluccio
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
    PLoS ONE 3:e2873. 2008
    ..melanogaster. These results suggest that the primary function of the yeast ascospore is as a cell type specialized for dispersion by insect vectors...
  26. pmc A conserved regulatory role for antisense RNA in meiotic gene expression in yeast
    Huei Mei Chen
    Department of Microbiology and Molecular Genetics, Stony Brook University, Stony Brook, NY 11794 5215, United States
    Curr Opin Microbiol 14:655-9. 2011
    ..While the mechanism(s) by which these antisense RNAs interfere with production of sense transcripts is not yet understood, the effects appear to be independent of the canonical RNAi machinery...
  27. pmc A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast
    Chien Lam
    Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA
    Eukaryot Cell 13:383-91. 2014
    ..These results reveal the architecture of the LEP and provide insight into the evolution of this membrane-organizing complex. ..
  28. pmc Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae
    Mark E Nickas
    Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York, Stony Brook, New York 11794 5215, USA
    Genetics 160:1439-50. 2002
    ..Our results suggest that Ady3p mediates assembly of the Don1p-containing structure at the leading edge of the prospore membrane via interaction with components of the SPB and that this structure is involved in spore wall formation...
  29. pmc Biological imaging by soft x-ray diffraction microscopy
    David Shapiro
    Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794 3800, USA
    Proc Natl Acad Sci U S A 102:15343-6. 2005
    ....