Research Topics
| Lygia StewartSummaryCountry: USA Publications
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Publications
The association between body mass index and severe biliary infections: a multivariate analysisLygia Stewart
Department of Surgery, University of California San Francisco, San Francisco, CA 94121, USA
Am J Surg 204:574-9. 2012..It is a risk factor for cholesterol gallstones, but little is known about associations between body mass index (BMI) and biliary infections. We studied this using factors associated with biliary infections...
Elderly patients have more severe biliary infections: influence of complement-killing and induction of TNFalpha productionLygia Stewart
Department of Surgery, University of California, San Francisco, CA 94121, USA
Surgery 143:103-12. 2008..We noted previously that bacterial serum-sensitivity and induction of TNFalpha production in sera (iTNFsera) were associated with severe biliary infections. We examined the influence of age and these factors on illness severity...
Bacteria entombed in the center of cholesterol gallstones induce fewer infectious manifestations than bacteria in the matrix of pigment stonesLygia Stewart
Department of Surgery, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
J Gastrointest Surg 11:1298-308. 2007..The clinical significance of bacteria in the pigment centers of cholesterol stones is unknown. We compared the infectious manifestations and characteristics of bacteria from pigment stones and predominantly cholesterol stones...
Gallstones containing bacteria are biofilms: bacterial slime production and ability to form pigment solids determines infection severity and bacteremiaLygia Stewart
Department of Surgery 112, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
J Gastrointest Surg 11:977-83; discussion 983-4. 2007..Slime production facilitates adherence, whereas beta-glucuronidase and phospholipase generate colonization surface. These factors facilitate gallstone formation, but their influence on infection severity is unknown...
Biliary bacterial factors determine the path of gallstone formationLygia Stewart
Department of Surgery, University of California San Francisco, San Francisco, CA 94121, USA
Am J Surg 192:598-603. 2006..Bacterial factors that facilitate gallstone formation include beta-glucuronidase (bG), phospholipase (PhL), and slime. The current study sought to determine whether bacterial factors influence the path of gallstone formation...
Right hepatic artery injury associated with laparoscopic bile duct injury: incidence, mechanism, and consequencesLygia Stewart
Department of Surgery, University of California San Francisco, San Francisco, California 94121, USA
J Gastrointest Surg 8:523-30; discussion 530-1. 2004..A similar increase in the complication rate was not seen in patients treated by a biliary specialist...
Cholangitis: bacterial virulence factors that facilitate cholangiovenous reflux and tumor necrosis factor-alpha productionLygia Stewart
Department of Surgery 112, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
J Gastrointest Surg 7:191-8; discussion 198-9. 2003..The most virulent bacterial species (from patients with sepsis) were killed by complement, but they still had significant CVR and were associated with increased TNF-alpha production...
Pathogenesis of pigment gallstones in Western societies: the central role of bacteriaLygia Stewart
Department of Surgery, San Francisco State University, San Francisco, CA, USA
J Gastrointest Surg 6:891-903; discussion 903-4. 2002..Thus bacteria have a major role in Western pigment gallstone formation. Furthermore, gallstone color did not predict composition or bacterial presence...
Laparoscopic treatment of liver tumours using a two-needle probe bipolar radiofrequency ablation deviceFarzad Alemi
Department of Surgery, University of California, and San Francisco VA Medical Center, San Francisco, CA 94121, USA
HPB (Oxford) 13:656-64. 2011..Additionally, B-RFA can precoagulate parenchyma to assist in hepatic resection. Herein, we report our early experience using B-RFA...
Spectrum of gallstone disease in the veterans populationLygia Stewart
Department of Surgery, University of California San Francisco, San Francisco, CA, USA
Am J Surg 190:746-51. 2005..Patients with E coli and/or Klebsiella species commonly showed infectious manifestations, patients with Enterococcus were in an intermediate range, and those with other species had few infectious manifestations...
Neuroendocrine tumors of the ampulla of Vater: biological behavior and surgical managementJonathan T Carter
Department of Surgery, University of California, San Francisco, 4 Koret Way, LR 101, Box 0475, San Francisco, CA 94143 0475, USA
Arch Surg 144:527-31. 2009..To describe the biological behavior and surgical management of ampullary neuroendocrine tumors in 7 patients...
Gram-negative bacteria killed by complement are associated with more severe biliary infections and produce more tumor necrosis factor-alpha in seraLygia Stewart
Department of Surgery, University of California San Francisco, USA
Surgery 132:408-14. 2002..This suggests a potential role for complement activation and cytokine production in biliary sepsis...
Causes and prevention of laparoscopic bile duct injuries: analysis of 252 cases from a human factors and cognitive psychology perspectiveLawrence W Way
Department of Surgery, University of California-San Francisco, 513 Parnassus Avenue, S-550, San Francisco, CA 94143-0475, USA
Ann Surg 237:460-9. 2003....
Operative reports: form and functionLygia Stewart
Department of Surgery, University of California San Francisco, 4 Koret Way, San Francisco, CA 94143 0475, USA
Arch Surg 145:865-71. 2010....
Hepatic surgery at a VA tertiary medical center: lessons learnedFarzad Alemi
Department of Surgery, University of California, San Francisco, USA
Am J Surg 200:591-5. 2010..The development of a hepatic surgery center within a US Department of Veterans Affairs hospital is dependent on proper training and institutional support, which can translate into low operative morbidity and mortality rates...
Tumors of the ampulla of vater: histopathologic classification and predictors of survivalJonathan T Carter
Department of Surgery, University of California, San Francisco, CA 94143 0475, USA
J Am Coll Surg 207:210-8. 2008..The histology and clinical behavior of ampullary tumors vary substantially. We speculated that this might reflect the presence of two kinds of ampullary adenocarcinoma: pancreaticobiliary and intestinal...
Bringing the skills laboratory home: an affordable webcam-based personal trainer for developing laparoscopic skillsSow Alfred Kobayashi
Department of Surgery, University of California, San Francisco, California 94143, USA
J Surg Educ 68:105-9. 2011..The purpose of this work was to develop a more flexible system of laparoscopic surgery training with demonstrated effectiveness and construct validity...
Bipolar pulse coagulation for resection of the cirrhotic liverCarlos U Corvera
Department of Surgery, University of California San Francisco, VA Medical Center, San Francisco, California 94121, USA
J Surg Res 136:182-6. 2006..The Gyrus hand piece (GHP) is a bipolar diathermy pulsation instrument that is similar in design to a large hemostat (Péan) clamp that divides tissue while the clamp remains closed...
The efficacy of medical team training: improved team performance and decreased operating room delays: a detailed analysis of 4863 casesFrancis A Wolf
Department of Surgery, University of California, San Francisco, CA, USA
Ann Surg 252:477-83; discussion 483-5. 2010..Medical team training (MTT) has been touted as a way to improve teamwork and patient safety in the operating room (OR)...
Local resection of ampullary tumorsAdam T Meneghetti
Department of Surgery, University of California San Francisco, San Francisco VA Medical Center, California 94121-0112, USA
J Gastrointest Surg 9:1300-6. 2005..No adenomas recurred as carcinomas, suggesting that local resection is appropriate for these tumors in the absence of dysplasia or atypia on preoperative biopsies...
