Walter W Steiner

Summary

Country: USA

Publications

  1. pmc Fission yeast hotspot sequence motifs are also active in budding yeast
    Walter W Steiner
    Department of Biology, Niagara University, Lewiston, New York, United States of America
    PLoS ONE 7:e53090. 2012
  2. pmc Important characteristics of sequence-specific recombination hotspots in Schizosaccharomyces pombe
    Walter W Steiner
    Department of Biology, Niagara University, Lewiston, New York 14109, USA
    Genetics 187:385-96. 2011
  3. pmc Novel nucleotide sequence motifs that produce hotspots of meiotic recombination in Schizosaccharomyces pombe
    Walter W Steiner
    Department of Biology, Niagara University, Lewiston, NY 14109, USA
    Genetics 182:459-69. 2009
  4. pmc Natural meiotic recombination hot spots in the Schizosaccharomyces pombe genome successfully predicted from the simple sequence motif M26
    Walter W Steiner
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Mol Cell Biol 25:9054-62. 2005
  5. ncbi Meiotic DNA breaks at the S. pombe recombination hot spot M26
    Walter W Steiner
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, A1 162, Seattle, WA 98109, USA
    Mol Cell 9:847-55. 2002
  6. pmc Activation of an alternative, rec12 (spo11)-independent pathway of fission yeast meiotic recombination in the absence of a DNA flap endonuclease
    Joseph A Farah
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 11200 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Genetics 171:1499-511. 2005
  7. pmc Optimizing the nucleotide sequence of a meiotic recombination hotspot in Schizosaccharomyces pombe
    Walter W Steiner
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Genetics 169:1973-83. 2005
  8. pmc A novel recombination pathway initiated by the Mre11/Rad50/Nbs1 complex eliminates palindromes during meiosis in Schizosaccharomyces pombe
    Joseph A Farah
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Genetics 169:1261-74. 2005
  9. ncbi Meiotic recombination remote from prominent DNA break sites in S. pombe
    Jennifer A Young
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Mol Cell 9:253-63. 2002
  10. pmc Multiple modes of chromatin configuration at natural meiotic recombination hot spots in fission yeast
    Kouji Hirota
    Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba 3 8 1, Meguroku, Tokyo 153 8902, Japan
    Eukaryot Cell 6:2072-80. 2007

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc Fission yeast hotspot sequence motifs are also active in budding yeast
    Walter W Steiner
    Department of Biology, Niagara University, Lewiston, New York, United States of America
    PLoS ONE 7:e53090. 2012
    ..The conservation of these hotspots between the distantly related fission and budding yeasts suggests that these sequence motifs, and others yet to be discovered, may function widely as hotspots in many diverse organisms...
  2. pmc Important characteristics of sequence-specific recombination hotspots in Schizosaccharomyces pombe
    Walter W Steiner
    Department of Biology, Niagara University, Lewiston, New York 14109, USA
    Genetics 187:385-96. 2011
    ..Each of these factors binds to its respective motifs in vitro. However, unlike CRE, the sequence required for hotspot activity is larger than the sequence required for binding, suggesting the involvement of additional factors...
  3. pmc Novel nucleotide sequence motifs that produce hotspots of meiotic recombination in Schizosaccharomyces pombe
    Walter W Steiner
    Department of Biology, Niagara University, Lewiston, NY 14109, USA
    Genetics 182:459-69. 2009
    ..We propose that many hotspots in S. pombe, and perhaps other organisms, result from simple sequence motifs, some of which are identified here...
  4. pmc Natural meiotic recombination hot spots in the Schizosaccharomyces pombe genome successfully predicted from the simple sequence motif M26
    Walter W Steiner
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Mol Cell Biol 25:9054-62. 2005
    ..M26 may be the first example among a diverse group of simple sequences that determine the distribution, and hence predictability, of meiotic recombination hot spots in eukaryotic genomes...
  5. ncbi Meiotic DNA breaks at the S. pombe recombination hot spot M26
    Walter W Steiner
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, A1 162, Seattle, WA 98109, USA
    Mol Cell 9:847-55. 2002
    ..Break frequency is strongly correlated with recombination frequency for these alleles. The occurrence of breaks at M26 suggests mechanistic similarities to hot spots in the distantly related yeast Saccharomyces cerevisiae...
  6. pmc Activation of an alternative, rec12 (spo11)-independent pathway of fission yeast meiotic recombination in the absence of a DNA flap endonuclease
    Joseph A Farah
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 11200 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Genetics 171:1499-511. 2005
    ..We compare the Rec* pathway to alternative pathways of homologous recombination in other organisms...
  7. pmc Optimizing the nucleotide sequence of a meiotic recombination hotspot in Schizosaccharomyces pombe
    Walter W Steiner
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Genetics 169:1973-83. 2005
    ....
  8. pmc A novel recombination pathway initiated by the Mre11/Rad50/Nbs1 complex eliminates palindromes during meiosis in Schizosaccharomyces pombe
    Joseph A Farah
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Genetics 169:1261-74. 2005
    ..Our studies provide a genetic and physical basis for frequent translocations between palindromes in human meiosis and identify a conserved meiotic process that constantly selects against palindromes in eukaryotic genomes...
  9. ncbi Meiotic recombination remote from prominent DNA break sites in S. pombe
    Jennifer A Young
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Mol Cell 9:253-63. 2002
    ..We infer that although recombination depends upon DNA breakage, recombination often occurs remote from these sites (tens of kilobases away); we discuss mechanisms by which this may occur...
  10. pmc Multiple modes of chromatin configuration at natural meiotic recombination hot spots in fission yeast
    Kouji Hirota
    Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba 3 8 1, Meguroku, Tokyo 153 8902, Japan
    Eukaryot Cell 6:2072-80. 2007
    ....

Research Grants1

  1. Sequence Determinants of Meiotic Recombination Hotspots
    Walter Steiner; Fiscal Year: 2007
    ..pombe are also active in the distantly related budding yeast Saccharomyces cerevisiae. Sequences that are active in both organisms may be widely conserved among eukaryotes, including man. ..