Haopeng Xu

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. ncbi request reprint TSP50 encodes a testis-specific protease and is negatively regulated by p53
    Haopeng Xu
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
    Cancer Res 67:1239-45. 2007
  2. pmc Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression
    Kegui Tian
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, NY 11794, USA
    BMC Cancer 8:327. 2008
  3. ncbi request reprint Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells
    Kegui Tian
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Cancer Res 65:10024-31. 2005
  4. ncbi request reprint WTH3, which encodes a small G protein, is differentially regulated in multidrug-resistant and sensitive MCF7 cells
    Kegui Tian
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Cancer Res 65:7421-8. 2005
  5. doi request reprint Differential methylation of TSP50 and mTSP50 genes in different types of human tissues and mouse spermatic cells
    Yu Huang
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, R402 Life Science Building, Stony Brook, NY 11794 5215, USA
    Biochem Biophys Res Commun 374:658-61. 2008

Research Grants

  1. A Novel Gene, WTH3, and Multidrug Resistance
    HAOPENG DUFFY; Fiscal Year: 2005

Collaborators

Detail Information

Publications5

  1. ncbi request reprint TSP50 encodes a testis-specific protease and is negatively regulated by p53
    Haopeng Xu
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
    Cancer Res 67:1239-45. 2007
    ..We also found that the quantity of Sp1 transcription factor was lower in MCF7/Adr than in MCF7 cells, which suggested that another mechanism (i.e., transcription factor modulation) was also involved in TSP50 differential expression...
  2. pmc Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression
    Kegui Tian
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, NY 11794, USA
    BMC Cancer 8:327. 2008
    ..WTH3 was also found to be directly targeted and up regulated by the p53 gene. Furthermore, over expression of the WTH3 gene promoted the apoptotic phenotype in various host cells...
  3. ncbi request reprint Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells
    Kegui Tian
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Cancer Res 65:10024-31. 2005
    ..Therefore, our studies suggested that the behavior of WTH3 in primary drug-resistant breast cancer epithelial cells was similar to that in a model system where epigenetic regulation of the WTH3 gene was linked to the MDR phenotype...
  4. ncbi request reprint WTH3, which encodes a small G protein, is differentially regulated in multidrug-resistant and sensitive MCF7 cells
    Kegui Tian
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    Cancer Res 65:7421-8. 2005
    ..Therefore, present studies support previous observations that WTH3, as a negative regulator, participates in MDR development in MCF7/AdrR cells...
  5. doi request reprint Differential methylation of TSP50 and mTSP50 genes in different types of human tissues and mouse spermatic cells
    Yu Huang
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, R402 Life Science Building, Stony Brook, NY 11794 5215, USA
    Biochem Biophys Res Commun 374:658-61. 2008
    ..Taken together, our findings suggested that DNA methylation might regulate the TSP50 and mTSP50 gene expressions in different types of tissues and spermatic cells...

Research Grants3

  1. A Novel Gene, WTH3, and Multidrug Resistance
    HAOPENG DUFFY; Fiscal Year: 2005
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