Robert Welliver

Summary

Affiliation: State University of New York at Buffalo
Country: USA

Publications

  1. ncbi request reprint The immune response to respiratory syncytial virus infection: friend or foe?
    Robert C Welliver
    Department of Pediatrics, School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA
    Clin Rev Allergy Immunol 34:163-73. 2008
  2. ncbi request reprint Innate immune responses in respiratory syncytial virus infections
    Subramaniam Krishnan
    Graduate Program in Microbiology and Immunology, Arizona Respiratory Center, University of Arizona HSC, Tucson, Arizona, USA
    Viral Immunol 17:220-33. 2004
  3. doi request reprint Effects of early environment on mucosal immunologic homeostasis, subsequent immune responses and disease outcome
    Pearay L Ogra
    Department of Pediatrics, Division of Infectious Diseases, University at Buffalo, State University of New York, School of Medicine, and Women and Children s Hospital of Buffalo, Buffalo, NY 14222, USA
    Nestle Nutr Workshop Ser Pediatr Program 61:145-81. 2008
  4. pmc Does the viral subtype influence the biennial cycle of respiratory syncytial virus?
    Gordana Mlinaric-Galinovic
    Department of Virology, Croatian National Institute of Public Health and University Medical School of Zagreb, Zagreb, Croatia
    Virol J 6:133. 2009
  5. pmc The biennial cycle of respiratory syncytial virus outbreaks in Croatia
    Gordana Mlinaric-Galinovic
    Department of Virology, Croatian National Institute of Public Health, Rockefellerova 12, 10000 Zagreb, Croatia
    Virol J 5:18. 2008
  6. doi request reprint Fatality rates in published reports of RSV hospitalizations among high-risk and otherwise healthy children
    Robert C Welliver
    School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Women and Children s Hospital, Buffalo, NY 14222, USA
    Curr Med Res Opin 26:2175-81. 2010
  7. doi request reprint Temperature, humidity, and ultraviolet B radiation predict community respiratory syncytial virus activity
    Robert C Welliver
    Division of Infectious Diseases, State University of New York at Buffalo and Women and Children s Hospital, Buffalo, NY 14222, USA
    Pediatr Infect Dis J 26:S29-35. 2007
  8. ncbi request reprint Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses
    Timothy P Welliver
    MedImmune, Inc, Gaithersburg, MD, USA
    J Infect Dis 195:1126-36. 2007
  9. ncbi request reprint Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection
    Robert C Welliver
    Department of Pediatrics, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, and the Division of Infectious Diseases, Children s Hospital of Buffalo, New York 14222, USA
    J Pediatr 143:S112-7. 2003
  10. doi request reprint The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus
    Robert Welliver
    State University of New York at Buffalo and Women and Children s Hospital of Buffalo, New York, USA
    Paediatr Respir Rev 10:6-8. 2009

Collaborators

Detail Information

Publications21

  1. ncbi request reprint The immune response to respiratory syncytial virus infection: friend or foe?
    Robert C Welliver
    Department of Pediatrics, School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA
    Clin Rev Allergy Immunol 34:163-73. 2008
    ..Thus, recovery from primary (and perhaps later) RSV infection is dependent on the quality of innate immune responses. These findings should have enormous significance to the development of vaccines and antiviral compounds...
  2. ncbi request reprint Innate immune responses in respiratory syncytial virus infections
    Subramaniam Krishnan
    Graduate Program in Microbiology and Immunology, Arizona Respiratory Center, University of Arizona HSC, Tucson, Arizona, USA
    Viral Immunol 17:220-33. 2004
    ....
  3. doi request reprint Effects of early environment on mucosal immunologic homeostasis, subsequent immune responses and disease outcome
    Pearay L Ogra
    Department of Pediatrics, Division of Infectious Diseases, University at Buffalo, State University of New York, School of Medicine, and Women and Children s Hospital of Buffalo, Buffalo, NY 14222, USA
    Nestle Nutr Workshop Ser Pediatr Program 61:145-81. 2008
    ....
  4. pmc Does the viral subtype influence the biennial cycle of respiratory syncytial virus?
    Gordana Mlinaric-Galinovic
    Department of Virology, Croatian National Institute of Public Health and University Medical School of Zagreb, Zagreb, Croatia
    Virol J 6:133. 2009
    ..In order to determine if these differences are accounted for by the circulation of different RSV subtypes, we studied the prevalence of RSV subtype A and B strains in Zagreb County from 1 January 2006 to 31 December 2007...
  5. pmc The biennial cycle of respiratory syncytial virus outbreaks in Croatia
    Gordana Mlinaric-Galinovic
    Department of Virology, Croatian National Institute of Public Health, Rockefellerova 12, 10000 Zagreb, Croatia
    Virol J 5:18. 2008
    ..Knowledge of this biennial pattern should be useful in predicting the onset of RSV outbreaks in Croatia, and would facilitate planning for the prevention and control of RSV infections in the region...
  6. doi request reprint Fatality rates in published reports of RSV hospitalizations among high-risk and otherwise healthy children
    Robert C Welliver
    School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Women and Children s Hospital, Buffalo, NY 14222, USA
    Curr Med Res Opin 26:2175-81. 2010
    ..To review the fatalities among children hospitalized with respiratory syncytial virus (RSV) infection, and identify factors leading to a fatal outcome...
  7. doi request reprint Temperature, humidity, and ultraviolet B radiation predict community respiratory syncytial virus activity
    Robert C Welliver
    Division of Infectious Diseases, State University of New York at Buffalo and Women and Children s Hospital, Buffalo, NY 14222, USA
    Pediatr Infect Dis J 26:S29-35. 2007
    ....
  8. ncbi request reprint Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses
    Timothy P Welliver
    MedImmune, Inc, Gaithersburg, MD, USA
    J Infect Dis 195:1126-36. 2007
    ..It is widely believed that both viral replication and inappropriately enhanced immune responses contribute to disease severity. In infants, RSV LRTI is known to be more severe than influenza virus LRTI...
  9. ncbi request reprint Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection
    Robert C Welliver
    Department of Pediatrics, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, and the Division of Infectious Diseases, Children s Hospital of Buffalo, New York 14222, USA
    J Pediatr 143:S112-7. 2003
    ..Pulmonary hypertension and cyanosis are associated with worse outcomes in infants with congenital heart disease, and prolonged viral replication accounts for more severe illness in immunocompromised individuals...
  10. doi request reprint The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus
    Robert Welliver
    State University of New York at Buffalo and Women and Children s Hospital of Buffalo, New York, USA
    Paediatr Respir Rev 10:6-8. 2009
    ..Accurate information on when to institute and withdraw prophylactic therapy against RSV will depend on local epidemiological data...
  11. doi request reprint Pharmacotherapy of respiratory syncytial virus infection
    Robert C Welliver
    Department of Pediatrics, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Women and Children s Hospital of Buffalo, Buffalo, New York, United States
    Curr Opin Pharmacol 10:289-93. 2010
    ....
  12. ncbi request reprint Respiratory syncytial virus and other respiratory viruses
    Robert C Welliver
    State University of New York and Children s Hospital of Buffalo, 219 Bryant Street, Buffalo, NY 14222, USA
    Pediatr Infect Dis J 22:S6-10; discussion S10-2. 2003
    ..Preliminary evidence suggests that severe RSV and influenza viral infections are mediated via chemokine up-regulation...
  13. doi request reprint Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases
    Timothy P Welliver
    MedImmune, Inc, Gaithersburg, MD, USA
    Pediatr Infect Dis J 27:S92-6. 2008
    ..Severe infantile RSV and influenza virus LRTI is characterized by inadequate (rather than excessive) adaptive immune responses, robust viral replication and apoptotic crisis...
  14. ncbi request reprint Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the respiratory tracts of human infants following paramyxovirus infection
    Matthew B Elliott
    Wyeth Research, Pearl River, NY 10965, USA
    J Med Virol 79:447-56. 2007
    ..Taken together, the data suggested that paramyxovirus infection perturbs MMP-9/TIMP-1 homeostasis that in turn may contribute to the severity of respiratory tract disease...
  15. ncbi request reprint Production of interferon gamma in respiratory syncytial virus infection of humans is not associated with interleukins 12 and 18
    Roberto P Garofalo
    Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA
    J Med Virol 73:289-94. 2004
    ..Immune responses characterized by relatively greater release of IL18 may be associated with milder forms of bronchiolitis...
  16. ncbi request reprint Respiratory syncytial virus infection: therapy and prevention
    Robert C Welliver
    Department of Pediatrics, State University of New York at Buffalo and Children s Hospital of Buffalo, NY 14222, USA
    Paediatr Respir Rev 5:S127-33. 2004
  17. ncbi request reprint Differences in participation of innate and adaptive immunity to respiratory syncytial virus in adults and neonates
    Subramaniam Krishnan
    Graduate Program in Microbiology and Immunology, University of Arizona Health Sciences Center, Tucson, USA
    J Infect Dis 188:433-9. 2003
    ..Thus, exposure to RSV does not appear to occur before birth, and adaptive immune insufficiency or greater innate responses may account for early life RSV-induced illnesses...
  18. ncbi request reprint Zileuton reduces respiratory illness and lung inflammation, during respiratory syncytial virus infection, in mice
    R Charles Welliver
    Department of Pediatrics, Division of Infectious Diseases, State University of New York at Buffalo, and Children s Hospital, Buffalo, New York 14222, USA
    J Infect Dis 187:1773-9. 2003
    ..Leukotrienes appear to contribute substantially to the pathogenesis of RSV-related disease...
  19. ncbi request reprint A comparison of epidemiologic and immunologic features of bronchiolitis caused by influenza virus and respiratory syncytial virus
    Roberto P Garofalo
    Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA
    J Med Virol 75:282-9. 2005
    ....
  20. ncbi request reprint The compound DATEM inhibits respiratory syncytial virus fusion activity with epithelial cells
    Shinpei Ohki
    Department of Physiology and Biophysics, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Antiviral Res 58:115-24. 2003
    ..DATEM may prove to be effective in limiting the infectivity of RSV by interference with the fusion of the viral envelope with target cell membranes...
  21. ncbi request reprint Beta-chemokines, but neither T helper type 1 nor T helper type 2 cytokines, correlate with severity of illness during respiratory syncytial virus infection
    Robert C Welliver
    Department of Pediatrics, State University of New York at Buffalo, Children s Hospital of Buffalo, USA
    Pediatr Infect Dis J 21:457-61. 2002