Marc J Shapiro
Affiliation: State University of New York
- Let the surgeon sleep: trauma team activation for severe hypotensionMarc J Shapiro
Department of Surgery, Stony Brook University School of Medicine and University Hospital, Stony Brook, New York 11794 8191, USA
J Trauma 65:1245-50; discussion 1250-2. 2008..Our level I academic trauma center changed the systolic blood pressure (SBP) requirement for trauma team activation (TTA) from 90 mm Hg to 80 mm Hg. This investigation was undertaken to determine the effects of such change...
- To filter blood or universal leukoreduction: what is the answer?Marc J Shapiro
SUNY Stony Brook School of Medicine, General Surgery, New York, USA
Crit Care 8:S27-30. 2004..Although leukoreduction will add cost to a unit of blood, projections indicate that leukoreduced blood will become the standard of care...
- Venous thromboembolic events in hospitalized trauma patientsMichelle C Azu
HSC T 19 090, Stony Brook, NY 11794 8191, USA
Am Surg 73:1228-31. 2007..Patients with ISS greater than 15, need for operation, spinal cord injuries, lower extremity fractures, and certain thoracic injuries are at risk for VTE...
- Ventilator-associated pneumonia in pediatric trauma patientsBreena R Taira
Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY, USA
Pediatr Crit Care Med 10:491-4. 2009..No study has characterized VAP in pediatric trauma patients. We determined the rates of and potential risk factors for VAP in pediatric trauma patients...
- Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic ratsSubir R Maitra
Department of Emergency Medicine, School of Medicine, State University of New York, Stony Brook, NY, USA
Crit Care Med 33:1577-81. 2005..CMT-3 posttreatment increased TIMP-1 level and thereby inhibited MMP-9, which in turn decreased TGF-beta1 and caspase-3 signaling pathways and improved survivability in septic rats...
- Venous thromboembolic events in pediatric trauma patients: is prophylaxis necessary?Michelle C Azu
Department of Surgery, Stony Brook University Hospital, Stony Brook, New York 11974, USA
J Trauma 59:1345-9. 2005..Invasive and noninvasive prophylactic therapies are used to prevent VTE in trauma patients. The risk of VTE in pediatric patients is not well known. Is VTE prophylaxis necessary in the pediatric trauma population?..
- Role of chemically modified tetracycline on TNF-alpha and mitogen-activated protein kinases in sepsisSubir R Maitra
Trauma Research Laboratory, Department of Emergency Medicine, School of Medicine, State University of New York, Stony Brook, NY 11794 7400, USA
Shock 22:478-81. 2004..These results indicate increased activity of TNF-alpha and MAPK following sepsis and demonstrate the beneficial effect of CMT-3 in preventing the increase in TNF-alpha, p38 MAPK, p42/44 MAPK, and the progression of septic shock...
- Inhibition of matrix metalloproteinase on hepatic transforming growth factor beta1 and caspase-3 activation in hemorrhageSubir R Maitra
Department of Emergency Medicine, School of Medicine, Stony Brook University Hospital, Stony Brook, NY 11794 7400, USA
Acad Emerg Med 12:797-803. 2005....
- The importance of basic science and clinical research as a selection criterion for general surgery residency programsMark M Melendez
Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY, 11794 8191, USA
J Surg Educ 65:151-4. 2008..This study aimed to evaluate the relative importance of basic science and clinical research in the selection criteria used by program directors (PDs)...
- Wall suction applied to needle muscle biopsy - a novel technique for increasing sample sizeMark M Melendez
Department of Surgery, Stony Brook University Medical Center, State University of New York at Stony Brook, Stony Brook, New York 11794 8191, USA
J Surg Res 142:301-3. 2007..To evaluate the effectiveness of a novel technique to obtain adequate sample size using wall suction applied to needle muscle biopsy, we collected samples from subjects in on-going clinical studies for gene expression...
- Anemia and blood transfusion in trauma patients admitted to the intensive care unitMarc J Shapiro
Department of Surgery, Saint Louis University, Missouri 63110 0250, USA
J Trauma 55:269-73; discussion 273-4. 2003..The issue of blood use in critically injured patients requires evaluation...
- Human intestinal epithelial and smooth muscle cells are potent producers of IL-6Edmond K Ng
Department of Surgery, Saint Louis University School of Medicine, St Louis, MO, USA
Mediators Inflamm 12:3-8. 2003..We therefore studied the capacity of differentiated human intestinal epithelial and smooth muscle cell lines to produce IL-6 in response to various proinflammatory stimuli...
- High-fidelity medical simulation as an assessment tool for pediatric residents' airway management skillsFrank L Overly
Department of Emergency Medicine, Rhode Island Hospital, Providence, RI 02903, USA
Pediatr Emerg Care 23:11-5. 2007..To evaluate high-fidelity medical simulation as an assessment tool for pediatric residents' ability to manage an acute airway...
- Where have all the surgical intensivists gone?Marc J Shapiro
Crit Care Med 34:2485-6. 2006
- A simulation-based biodefense and disaster preparedness curriculum for internal medicine residentsEleanor M Summerhill
Internal Medicine Residency Program, Department of Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI 02860, USA
Med Teach 30:e145-51. 2008..Given that victims may present to a variety of healthcare venues, including primary care practices, inpatient hospital wards, and intensive care units, we developed a curriculum to address this need...
- The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United StatesHoward L Corwin
Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
Crit Care Med 32:39-52. 2004..To quantify the incidence of anemia and red blood cell (RBC) transfusion practice in critically ill patients and to examine the relationship of anemia and RBC transfusion to clinical outcomes...
- Portable advanced medical simulation for new emergency department testing and orientationLeo Kobayashi
Department of Emergency Medicine, Brown Medical School, Providence, RI, USA
Acad Emerg Med 13:691-5. 2006..The authors used advanced medical simulation (SIM) to evaluate the capacity of a new ED for emergent resuscitative processes and assist facility orientation before opening day...