Robert Sack

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. doi request reprint Protein array characterization of bioactive proteins secreted by immortalized human corneal epithelium in response to pseudomonas constituents
    Robert Sack
    Department of Biological Sciences, SUNY Optometry, New York, New York 10036, USA
    Curr Eye Res 34:92-8. 2009
  2. ncbi request reprint Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: angiogenin and other defense system constituents
    Robert A Sack
    SUNY Optometry, New York, New York, USA
    Invest Ophthalmol Vis Sci 46:1228-38. 2005
  3. ncbi request reprint Antibody array characterization of inflammatory mediators in allergic and normal tears in the open and closed eye environments
    Robert Sack
    SUNY College of Optometry, 33 West 42nd Street, New York, NY 10036, USA
    Exp Eye Res 85:528-38. 2007
  4. pmc Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy
    Michal Laniado Schwartzman
    Department of Pharmacology, New York Medical College, Valhalla, New York, USA
    Diabetes 59:1780-8. 2010
  5. ncbi request reprint Tear turnover and immune and inflammatory processes in the open-eye and closed-eye environments: relationship to extended wear contact lens use
    Robert A Sack
    SUNY College of Optometry, Manhattan, NY 10036, USA
    Eye Contact Lens 29:S80-2; discussion S83-4, S192-4. 2003
  6. ncbi request reprint Is the cystatin-like domain of TSL functionally active in external ocular infections and during the normal diurnal cycle?
    Robert A Sack
    State University of New York State College of Optometry, 33 West 42nd Street at Bryant Park, Manhattan, NY 10036, USA
    Exp Eye Res 78:371-8. 2004
  7. ncbi request reprint AsialoGM1-mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5
    Jojo W Du
    Department of Biological Sciences, College of Optometry, State University of New York, 33 West 42nd Street, New York City, NY 10036, USA
    Invest Ophthalmol Vis Sci 47:4810-8. 2006
  8. ncbi request reprint Changes in the diurnal pattern of the distribution of gelatinases and associated proteins in normal and pathological tear fluids: evidence that the PMN cell is a major source of MMP activity in tear fluid
    Robert A Sack
    SUNY Optometry, New York, New York, USA
    Adv Exp Med Biol 506:539-45. 2002
  9. ncbi request reprint Interaction of Pseudomonas aeruginosa with human tear fluid components
    Nancy A McNamara
    Morton D Sarver Laboratory for Cornea and Contact Lens Research, School of Optometry, University of California, Berkeley, California, USA
    Curr Eye Res 30:517-25. 2005
  10. ncbi request reprint Tear glucose dynamics in diabetes mellitus
    Jennifer D Lane
    CIBA Vision Corporation, Duluth, GA, USA
    Curr Eye Res 31:895-901. 2006

Collaborators

  • SUZANNE M FLEISZIG
  • Andrea Leonardi
  • Jing Zhang
  • P S Reinach
  • Fan Zhang
  • Michal Laniado Schwartzman
  • Jojo W Du
  • Jennifer D Lane
  • Minjian Ni
  • Nancy A McNamara
  • Ann Beaton
  • Pavel Iserovich
  • Katherine Gotlinger
  • Michael W Dunn
  • Mauro Sartore
  • Lars Bellner
  • Maria Grazia Pertile
  • Sonal Sathe
  • Lynn Trieu
  • Henry Koziel
  • David M Krumholz
  • Fu Shin X Yu
  • Carol Morris
  • Souvenir D Tachado
  • José E Capó-Aponte
  • David J Evans
  • Renisa Andika
  • Samuel Hawgood
  • Mary Kwong
  • E Margot Anders

Detail Information

Publications11

  1. doi request reprint Protein array characterization of bioactive proteins secreted by immortalized human corneal epithelium in response to pseudomonas constituents
    Robert Sack
    Department of Biological Sciences, SUNY Optometry, New York, New York 10036, USA
    Curr Eye Res 34:92-8. 2009
    ..To use protein arrays to delineate the spectrum of angiogenic bioactive protein modulators that might be secreted and up-regulated by the corneal epithelium in response to killed bacterial products...
  2. ncbi request reprint Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: angiogenin and other defense system constituents
    Robert A Sack
    SUNY Optometry, New York, New York, USA
    Invest Ophthalmol Vis Sci 46:1228-38. 2005
    ..To adapt membrane-bound antibody array (MA) technology to characterize the distribution of a wide range of bioactive trace proteins in reflex (RTF) and open-eye (OTF) and closed-eye (CTF) tear samples...
  3. ncbi request reprint Antibody array characterization of inflammatory mediators in allergic and normal tears in the open and closed eye environments
    Robert Sack
    SUNY College of Optometry, 33 West 42nd Street, New York, NY 10036, USA
    Exp Eye Res 85:528-38. 2007
    ..Other than a modest increase in IL-8, no change could be observed in the profile of OTF after induction of an acute allergic reaction...
  4. pmc Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy
    Michal Laniado Schwartzman
    Department of Pharmacology, New York Medical College, Valhalla, New York, USA
    Diabetes 59:1780-8. 2010
    ..This study was aimed at obtaining a profile of lipids and proteins with a paracrine function in normal and diabetic vitreous and exploring whether the profile correlates with retinal pathology...
  5. ncbi request reprint Tear turnover and immune and inflammatory processes in the open-eye and closed-eye environments: relationship to extended wear contact lens use
    Robert A Sack
    SUNY College of Optometry, Manhattan, NY 10036, USA
    Eye Contact Lens 29:S80-2; discussion S83-4, S192-4. 2003
  6. ncbi request reprint Is the cystatin-like domain of TSL functionally active in external ocular infections and during the normal diurnal cycle?
    Robert A Sack
    State University of New York State College of Optometry, 33 West 42nd Street at Bryant Park, Manhattan, NY 10036, USA
    Exp Eye Res 78:371-8. 2004
    ..To test whether the cystatin-like functional domain in tear specific lipocalin (TSL) is functionally active in tears during the normal diurnal cycle and during external ocular infections...
  7. ncbi request reprint AsialoGM1-mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5
    Jojo W Du
    Department of Biological Sciences, College of Optometry, State University of New York, 33 West 42nd Street, New York City, NY 10036, USA
    Invest Ophthalmol Vis Sci 47:4810-8. 2006
    ....
  8. ncbi request reprint Changes in the diurnal pattern of the distribution of gelatinases and associated proteins in normal and pathological tear fluids: evidence that the PMN cell is a major source of MMP activity in tear fluid
    Robert A Sack
    SUNY Optometry, New York, New York, USA
    Adv Exp Med Biol 506:539-45. 2002
  9. ncbi request reprint Interaction of Pseudomonas aeruginosa with human tear fluid components
    Nancy A McNamara
    Morton D Sarver Laboratory for Cornea and Contact Lens Research, School of Optometry, University of California, Berkeley, California, USA
    Curr Eye Res 30:517-25. 2005
    ..In this study, we assessed the effect of eye closure and the role of sialoglycoprotein (SG) in tears on bacterial binding and invasion...
  10. ncbi request reprint Tear glucose dynamics in diabetes mellitus
    Jennifer D Lane
    CIBA Vision Corporation, Duluth, GA, USA
    Curr Eye Res 31:895-901. 2006
    ..Although it is possible to determine the diabetic status of a subject using tear glucose values alone, in the clinical setting this may not prove to be practical due to technical limitations...
  11. pmc Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa
    Minjian Ni
    School of Optometry, University of California, Berkeley, CA 94720 2020
    Infect Immun 73:2147-56. 2005
    ..aeruginosa invasion. Whether SP-D plays other roles in the regulation of other innate or adaptive immune responses at the ocular surface, as it does in the airways, remains to be explored...