Jagat J Mukherjee

Summary

Affiliation: State University of New York College at Buffalo
Country: USA

Publications

  1. pmc Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, 1300 Elmwood Avenue, Buffalo, NY 14222, USA
    Carcinogenesis 27:631-8. 2006
  2. pmc Inhibition of benzopyrene diol epoxide-induced apoptosis by cadmium(II) is AP-1-independent: role of extracelluler signal related kinase
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, Buffalo, NY 14222, USA
    Chem Biol Interact 172:72-80. 2008
  3. pmc DNA synthesis inhibition in response to benzo[a]pyrene dihydrodiol epoxide is associated with attenuation of p(34)cdc2: Role of p53
    Jagat J Mukherjee
    State University of New York College, Buffalo, NY 14222, USA
    Mutat Res 755:61-7. 2013
  4. doi request reprint Inhibition of benzopyrene-diol-epoxide (BPDE)-induced bax and caspase-9 by cadmium: role of mitogen activated protein kinase
    Jagat J Mukherjee
    State University of New York College at Buffalo, Environ Toxicol and Chem, Great Lakes Center, 1300 Elmwood Avenue, Buffalo, NY 14222, United States
    Mutat Res 661:41-6. 2009
  5. ncbi request reprint Effects of cadmium(II) on (+/-)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage response in human fibroblasts and DNA repair: a possible mechanism of cadmium's cogenotoxicity
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, 1300 Elmwood Avenue, Buffalo, New York 14222, USA
    Chem Res Toxicol 17:287-93. 2004
  6. pmc Phenolic fraction of tobacco smoke inhibits BPDE-induced apoptosis response and potentiates cell transformation: role of attenuation of p53 response
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, United States
    Chem Res Toxicol 24:698-705. 2011
  7. pmc Phenolic fraction of tobacco smoke condensate potentiates benzo[a]pyerene diol epoxide-induced cell transformation: role of protein kinase C
    Jagat J Mukherjee
    Great Lakes Center, State University of New York College, Buffalo, NY 14222, USA
    Mutat Res 696:89-94. 2010

Research Grants

Collaborators

Detail Information

Publications7

  1. pmc Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, 1300 Elmwood Avenue, Buffalo, NY 14222, USA
    Carcinogenesis 27:631-8. 2006
    ..Overall, our data suggest that abrogation of BPDE-induced p53 response and of NFkappaB activation by TPA is mediated by impairment of the signaling pathway involving p38 MAPK...
  2. pmc Inhibition of benzopyrene diol epoxide-induced apoptosis by cadmium(II) is AP-1-independent: role of extracelluler signal related kinase
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, Buffalo, NY 14222, USA
    Chem Biol Interact 172:72-80. 2008
    ..We suggest that cadmium inhibits BPDE-induced apoptosis not involving AP-1 but probably through a different mechanism by up-regulating ERK which is known to promote cell survival...
  3. pmc DNA synthesis inhibition in response to benzo[a]pyrene dihydrodiol epoxide is associated with attenuation of p(34)cdc2: Role of p53
    Jagat J Mukherjee
    State University of New York College, Buffalo, NY 14222, USA
    Mutat Res 755:61-7. 2013
    ....
  4. doi request reprint Inhibition of benzopyrene-diol-epoxide (BPDE)-induced bax and caspase-9 by cadmium: role of mitogen activated protein kinase
    Jagat J Mukherjee
    State University of New York College at Buffalo, Environ Toxicol and Chem, Great Lakes Center, 1300 Elmwood Avenue, Buffalo, NY 14222, United States
    Mutat Res 661:41-6. 2009
    ..Our results suggest that cadmium inhibits BPDE-induced apoptosis by modulating apoptotic signaling through up-regulation of ERK, which is known to promote cell survival...
  5. ncbi request reprint Effects of cadmium(II) on (+/-)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage response in human fibroblasts and DNA repair: a possible mechanism of cadmium's cogenotoxicity
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, 1300 Elmwood Avenue, Buffalo, New York 14222, USA
    Chem Res Toxicol 17:287-93. 2004
    ..The effect of cadmium on these processes may explain, at least partly, the potentiating effect of the metal on the genotoxicity of BP...
  6. pmc Phenolic fraction of tobacco smoke inhibits BPDE-induced apoptosis response and potentiates cell transformation: role of attenuation of p53 response
    Jagat J Mukherjee
    Environmental Toxicology and Chemistry Laboratory, Great Lakes Center, State University of New York College at Buffalo, United States
    Chem Res Toxicol 24:698-705. 2011
    ..Although p53-mediated NF-κB activation has a role in apoptosis induction, the role of NF-κB in TSCPhFr-mediated potentiation of PAH-induced cell transformation is not clear from our studies...
  7. pmc Phenolic fraction of tobacco smoke condensate potentiates benzo[a]pyerene diol epoxide-induced cell transformation: role of protein kinase C
    Jagat J Mukherjee
    Great Lakes Center, State University of New York College, Buffalo, NY 14222, USA
    Mutat Res 696:89-94. 2010
    ..Our data suggest a possible role of PKC down-regulation in potentiation of BPDE-induced tumorogenicity by TSC phenolic fraction...

Research Grants1

  1. Attenuation of p53 Response to PAHs by Tumor Promoters
    JAGAT MUKHERJEE; Fiscal Year: 2002
    ....