Research Topics
| Samy I McFarlaneSummaryAffiliation: State University of New York Country: USA Publications
| Collaborators
|
Detail Information
Publications
Role of angiotensin receptor blockers in diabetes: implications of recent clinical trialsSamy I McFarlane
Division of Endocrinology, Medical Director of Clinical Research, College of Medicine, State University of New York Downstate Medical Center, Kings County Hospital Center, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203, USA
Expert Rev Cardiovasc Ther 7:1363-71. 2009..Whether all ARBs are equally cardioprotective is uncertain. Data indicate that the beneficial effects of telmisartan may be drug specific rather than constitute a 'class effect.'..
Diabetes mellitus and the risk of cancerA Pandey
Department of Medicine, SUNY Downstate Medical Centre, New York, USA
Minerva Endocrinol 36:187-209. 2011..We will also discuss the role of insulin, metformin and other antidiabetic agents in cancer risk...- Insulin therapy and type 2 diabetes: management of weight gainSamy I McFarlane
Division of Endocrinology, College of Medicine, State University of New York Downstate, Brooklyn, NY 11203, USA
J Clin Hypertens (Greenwich) 11:601-7. 2009..The use of basal insulin analogs may offer advantages over conventional human insulin preparations in terms of more physiologic time-action profiles, reduced risk of hypoglycemia, and reduced weight gain... - Trends in mineral metabolism: Kidney Early Evaluation Program (KEEP) and the National Health and Nutrition Examination Survey (NHANES) 1999-2004Joseph A Vassalotti
National Kidney Foundation, Mount Sinai School of Medicine, One Gustave L Levy Pl, Nephrology Box 1243, New York, NY 10029 6574, USA
Am J Kidney Dis 51:S56-68. 2008..No study specifically examined mineral metabolism trends in a generalizable sample of patients at increased CKD risk... - Cardiovascular disease risk reduction with sleep apnea treatmentGirardin Jean-Louis
Brooklyn Health Disparities Center, Department of Medicine, SUNY Downstate Medical Center, NY 11203 2098, USA
Expert Rev Cardiovasc Ther 8:995-1005. 2010..Perspectives on emerging therapeutic approaches and promising areas of clinical and experimental research are also discussed... - New-onset diabetes after hemodialysis initiation: impact on survivalMoro O Salifu
SUNY Downstate Medical Center, Brooklyn, NY, USA
Am J Nephrol 31:239-46. 2010..The incidence of new-onset diabetes after initiation of hemodialysis (NODAD) and its impact on survival is not known... - Control of blood pressure and other cardiovascular risk factors at different practice settings: outcomes of care provided to diabetic women compared to menSamy I McFarlane
SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203, USA
J Clin Hypertens (Greenwich) 7:73-80. 2005..These observations underscore the need for better strategies for control of CVD risk in the diabetic population in general, and women in particular... - Hypertension and obesityAshish Aneja
Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York 11203, USA
Recent Prog Horm Res 59:169-205. 2004..Antihypertensives are considered important components in the holistic approach to the management of this complex problem... 
Comparison of the CKD Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) study equations: prevalence of and risk factors for diabetes mellitus in CKD in the Kidney Early Evaluation Program (KEEP)Samy I McFarlane
Division of Endocrinology, SUNY Downstate and Kings County Hospital Centers, Brooklyn, NY 11203, USA
Am J Kidney Dis 57:S24-31. 2011....- Heart failure in diabetic patients: utility of beta-blockadeDmitri Kirpichnikov
Lutheran Medical Center, Brooklyn, New York, USA
J Card Fail 9:333-44. 2003..CONCLUSIONS: Based on retrospective analysis, beta-blocking agents with vasodilating properties may provide additional benefits in diabetic patients because they may improve insulin sensitivity and vasorelaxation... - Therapeutic interventions for hypertension in metabolic syndrome: a comprehensive approachSudha Ganne
State University of New York, Division of Endocrinology, Diabetes and Hypertension, Downstate Medical Center, Brooklyn, NY, USA
Expert Rev Cardiovasc Ther 5:201-11. 2007..In this article, we review the pathophysiology and provide a rationale for the current therapeutic options in light of the most recent clinical trials in the field... - Prevalence and associations of anemia of CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004Samy I McFarlane
Division of Endocrinology, SUNY Downstate and Kings County Hospital Centers, Brooklyn, NY 11203, USA
Am J Kidney Dis 51:S46-55. 2008..We compared anemia prevalence and characteristics in the National Kidney Foundation Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004 populations... - Effect of ethnicity on the progression of diabetic kidney disease independent of glycemic controlMoro O Salifu
State University of New York Downstate Medical Center and Kings County Hospital Center, VA Medical Center, Brooklyn, NY, USA
Am J Nephrol 30:261-7. 2009..Whether the higher rate of estimated glomerular filtration rate (eGFR) decline in African-Americans is mediated by poor glycemic control is unclear... - Telmisartan and cardioprotectionPhilippe R Akhrass
State University of New York, Downstate Medical Center, Brooklyn, NY 11203, USA
Vasc Health Risk Manag 7:677-83. 2011.... - Cardiometabolic syndrome: pathophysiology and treatmentJonathan P Castro
Division of Endocrinology, Diabetes and Hypertension, State University of New York Downstate and Brooklyn Veterans Affairs Medical Center, Brooklyn, NY 11203, USA
Curr Hypertens Rep 5:393-401. 2003.... - Prevention of type 2 DM: implications for adolescents and young adultsJocelyne G Karam
Division of Endocrinology, SUNY Downstate and Kings County Hospital Center, Brooklyn, NY, USA
Pediatr Endocrinol Rev 5:980-8. 2008..We also highlight the ongoing efforts for diabetes prevention in trials specifically designed to address the adolescent population... - Hypertension after renal transplantFasika Tedla
SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
J Clin Hypertens (Greenwich) 9:538-45. 2007..In this review, the authors outline the pathogenesis, diagnostic workup, and treatment of hypertension after renal transplant... - Prevention of type 2 diabetes: an updateAmal Farag
Division of Endocrinology, Veterans Administration, New York Harbor Healthcare System, 800 Poly Place, Brooklyn, NY 11209, USA
Curr Diab Rep 7:200-7. 2007.... - Anemia and cardiovascular disease in diabetic nephropathySamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, State University of New York Health Science Center at Brooklyn, Kings County Hospital Center, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203 2098, USA
Curr Diab Rep 6:213-8. 2006.... - Stroke prevention in diabetic and other high cardiovascular risk patientsFadi El-Atat
Division of Stroke and Critical Care, Department of Neurology, Columbia University Medical Center, 710 West 168th Street, Room 552, New York, NY 10032, USA
Curr Diab Rep 5:200-7. 2005..These include hygienic and lifestyle changes, that if applied effectively could offer a great potential for stroke prevention and reduction of the cardiovascular burden in the diabetic populations... - Posttransplant diabetes and hypertension: pathophysiologic insights and therapeutic rationaleMoro O Salifu
State University of New York Downstate Medical Center, Renal Fellowship Program, 450 Clarkson Avenue, Box 52, Brooklyn, NY 11203, USA
Curr Diab Rep 8:221-7. 2008..This review outlines the pathogenesis, diagnostic workup, and therapeutic rationale for diabetes and hypertension after transplantation... - Prevention of type 2 diabetesSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, SUNY Downstate Health Science Center at Brooklyn Kings County Hospital Center, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203, USA
Curr Diab Rep 3:235-41. 2003..Other interventions are currently being examined in large prospective studies. It is likely that one or a combination of these approaches will make diabetes prevention a reality in the near future... - Calcium antagonists in patients with type 2 diabetes and hypertensionSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine and Biochemistry, State University of New York, Health Science Center at Brooklyn, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203, USA
Cardiovasc Drug Rev 21:105-18. 2003.... - Sudden cardiac death in patients with diabetesFadi A El-Atat
Division of Cardiovascular Diseases and Department of Medicine, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, New York, NY 10032, USA
Curr Diab Rep 4:187-93. 2004.... - Resistant hypertension and sleep apnea: pathophysiologic insights and strategic managementStephen K Williams
Center for Healthful Behavior Change, Division of General Internal Medicine, New York University School of Medicine, New York, NY 10010, USA
Curr Diab Rep 11:64-9. 2011..This review will address some of the epidemiologic data associating apnea with the pathogenesis of resistant hypertension. Diagnosis and management of apnea and its associated hypertension will also be considered... - Association of diabetes and hepatitis C infection: epidemiologic evidence and pathophysiologic insightsGul Bahtiyar
Division of Endocrinology, Diabetes and Hypertension, SUNY Downstate Health Science Center, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203, USA
Curr Diab Rep 4:194-8. 2004..In this article, we review the epidemiologic association between HCV and DM, highlighting the most recent pathophysiologic insights into the mechanisms underlying this association... - Mechanisms by which angiotensin-converting enzyme inhibitors prevent diabetes and cardiovascular diseaseSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, State University of New York, Health Science Center at Brooklyn, Brooklyn, New York 11203, USA
Am J Cardiol 91:30H-37H. 2003..This article explores potential mechanism by which ACE inhibition reduces the development of diabetes, improves these surrogate markers, and reduces cardiovascular disease and renal disease... - Diabetes prevention between RAAS inhibition and PPAR-gamma stimulation: the diabetes reduction assessment with ramipril and rosiglitazone medication (DREAM) trialSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, State University of New York Health Science Center and Kings County Hospital Center, Brooklyn, NY 11203, USA
J Cardiometab Syndr 2:149-50. 2007 - Update on the prevention of type 2 diabetesJocelyne G Karam
Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, NY 11219, USA
Curr Diab Rep 11:56-63. 2011..In this paper we present an update on prevention of type 2 diabetes highlighting the major recent trials completed to date in this very important area of investigation... - Oxidative stress, glucose metabolism, and the prevention of type 2 diabetes: pathophysiological insightsSyed Shah
Division of Endocrinology, Diabetes and Hypertension, Department of Internal Medicine, SUNY Downstate and Kings County Hospital Center, Brooklyn, NY 11203, USA
Antioxid Redox Signal 9:911-29. 2007..This comprehensive review highlights the role of oxidative stress in the pathogenesis of diabetes, with emphasis on the major clinical trials conducted on prevention of type 2 diabetes... - Alcohol consumption and blood pressure in the adult US population: assessment of gender-related effectsSamy I McFarlane
Division of Endocrinology Biostatistics, SUNY Downstate Medical Center Kings County Hospital, Brooklyn, New York 11203, USA
J Hypertens 25:965-70. 2007..Our objective was to assess the gender-related effects of alcohol consumption on blood pressure (BP) in a representative sample of the adult US population... - Heart failure: metabolic derangements and therapeutic rationaleYohannes Gebreegziabher
SUNY Downstate Medical Center, Division of Cardiovascular Medicine, 450 Clarkson Avenue, Brooklyn, NY 11203 2098, USA
Expert Rev Cardiovasc Ther 5:331-43. 2007.... - Admission hyperglycemia and length of hospital stay in patients with diabetes and heart failure: a prospective cohort studyYohannes Gebreegziabher
Department of Medicine, SUNY Downstate and King County Hospital Center, Brooklyn, NY, USA
Congest Heart Fail 14:117-20. 2008..31; P<.001) and average BG (r=0.34; P=.001). In patients with acute HF exacerbation, diabetes significantly prolonged LOS. Hyperglycemia correlated with LOS... - Metformin: an updateDmitri Kirpichnikov
State University of New York Health Science Center at Brooklyn, 450 Clarkson Avenue, Box 1205, Brooklyn, New York 11203, USA
Ann Intern Med 137:25-33. 2002.... - Heart disease in diabetic patientsMihaela C Blendea
Department of Medicine, State University of New York Health Science Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Curr Diab Rep 3:223-9. 2003..There is also increased sudden death associated with diabetes, which is due, in part, to the underlying autonomic neuropathy. This article reviews diabetic cardiac disease, with an emphasis on type 2 diabetes... - Stroke in patients with diabetes and hypertensionSamy I McFarlane
SUNY Downstate, Brooklyn, NY, USA
J Clin Hypertens (Greenwich) 7:286-92; quiz 293-4. 2005..In this review, the authors discuss the risk factors for stroke with emphasis on the diabetic and hypertensive population, highlighting the interventions that have been shown to decrease stroke risk in this patient population... - Hypertension in patients with Cushing's disease: pathophysiology, diagnosis, and managementAlan Sacerdote
Department of Medicine, S.U.N.Y. Health Science Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Curr Hypertens Rep 7:212-8. 2005.... - Cardiovascular disease in diabetes and the cardiometabolic syndrome: focus on minority womenJohn Nicasio
Department of Preventive Medicine and Community Health, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 43, Brooklyn, NY 11203, USA
Curr Diab Rep 5:208-13. 2005..In this article, we discuss CVD in people with diabetes and the CMS, with emphasis on minority women, a particularly vulnerable population... - Obstructive sleep apnea and cardiovascular disease: role of the metabolic syndrome and its componentsGirardin Jean-Louis
Brooklyn Center for Health Disparities, SUNY Downstate Medical Center Brooklyn, NY 11203 2098, USA
J Clin Sleep Med 4:261-72. 2008..e., central obesity, hypertension, diabetes, and dyslipidemia). Large-scale, population-based studies testing causal models linking among sleep apnea, cardiovascular morbidity, and metabolic syndrome are needed... - Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisalAnthony Accurso
State University of New York Downstate Medical Center, Brooklyn, New York, USA
Nutr Metab (Lond) 5:9. 2008..These beneficial effects of carbohydrate restriction do not require weight loss. Finally, the point is reiterated that carbohydrate restriction improves all of the features of metabolic syndrome... - Sleep duration and the risk of diabetes mellitus: epidemiologic evidence and pathophysiologic insightsFerdinand Zizi
Department of Medicine, SUNY Downstate Medical Center, Box 1199, 450 Clarkson Avenue, Brooklyn, NY 11203 2098, USA
Curr Diab Rep 10:43-7. 2010..Proposed mechanisms explaining associations between short sleep and diabetes are examined and clinical management of OSA among patients with diabetes is discussed... - Group visits in the management of diabetes and hypertension: effect on glycemic and blood pressure controlLisel M Loney-Hutchinson
Division of Endocrinology, State University of New York Downstate Medical Center, Kings County Hospital Center, Brooklyn, NY 11203, USA lisel
Curr Diab Rep 9:238-42. 2009..In this review, we highlight the magnitude of the diabetes epidemic, the barriers to optimal diabetes care, and the utility of the concept of group visits as a chronic disease management strategy for diabetes care... - Sleep apnea and diabetes: insights into the emerging epidemicA Pandey
Brooklyn Health Disparities Center, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1199, Brooklyn, NY 11203 2098, USA
Curr Diab Rep 11:35-40. 2011..Suggestions to improve practice guidelines in the management of diabetic patients with sleep apnea are provided... - Role of the natriuretic peptide system in cardiorenal protectionSamy I McFarlane
Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, State University of New York Health Science Center at Brooklyn, 11203, USA
Arch Intern Med 163:2696-704. 2003..We herein review some of these advances, including a new therapeutic strategy for potentially enhancing cardiorenal protection in patients with these disorders... - Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link?Samy I McFarlane
Department of Internal Medicine, Division of Endocrinology, SUNY Downstate, and Kings County Hospital Center, Brooklyn, NY 11203, USA
Endocrine 23:1-10. 2004..Therefore, additional research is necessary to further characterize the relationship between these two common illnesses... - Challenges in the diagnosis and management of new-onset diabetes after transplantationMoro O Salifu
SUNY Downstate Medical Center, Department of Medicine, Renal Fellowship Program, 450 Clarkson Avenue, Box 52, Brooklyn, NY 11203, USA
Curr Diab Rep 5:194-9. 2005..In this article, we discuss the epidemiology, risk factors, pathophysiology, clinical course, and therapeutic and diagnostic challenges of this emerging disease... - Antihypertensive medications and their effects on lipid metabolismMrunalini Deshmukh
Department of Medicine, Box 50, State University of New York Health Science Center at Brooklyn, Kings County Hospital Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Curr Diab Rep 8:214-20. 2008..This review outlines the need to control hypertension, options for several antihypertensive medications, their differing effects on lipid metabolism, and the clinical implications of their effects on lipid parameters... - CKD and cardiovascular disease in screened high-risk volunteer and general populations: the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004Peter A McCullough
Department of Medicine, Divisions of Cardiology, Nutrition, and Preventive Medicine, William Beaumont Hospital, Royal Oak, MI 48073, USA
Am J Kidney Dis 51:S38-45. 2008..Chronic kidney disease (CKD) is recognized as an independent cardiovascular disease risk state. The relationship between CKD and cardiovascular disease in volunteer and general populations has not been explored... - Sleep duration among black and white Americans: results of the National Health Interview SurveyJoao Nunes
Sophie Davis School of Biomedical Education, City College, New York, NY, USA
J Natl Med Assoc 100:317-22. 2008..However, little has been done to ascertain ethnic differences in sleep duration in a national sample. This study compares sleep duration in a sample of black and white participants in the National Health Interview Survey (NHIS)... - Bone mineral density in African–American women with symptomatic uterine leiomyomaOzgul Muneyyirci-Delale
Department of Medicine, State University of New York, Brooklyn, NY 11203, USA
Womens Health (Lond Engl) 6:673-7. 2010..This relationship, however, has not been previously described in African-American women. We aim to assess BMD in African-American women with symptomatic uterine leiomyoma... - Hypertension management in the high cardiovascular risk populationIlir Maraj
Division of Endocrinology, Diabetes, and Hypertension, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
Int J Hypertens 2013:382802. 2013..We will review hypertension management in the high cardiovascular risk population: patients with coronary heart disease (CHD) and heart failure (HF) as well as in diabetic patients... - High-dose atorvastatin after stroke or transient ischemic attack: The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) InvestigatorsJocelyne G Karam
State University of New York Health Science Center and Kings County Hospital Center, Brooklyn, NY, USA
J Cardiometab Syndr 3:68-9. 2008 - Cardiovascular endocrinology 1: aldosterone function in diabetes mellitus: effects on cardiovascular and renal diseaseSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine at State University of New York, Health Science Center at Brooklyn, Kings County Hospital Center, and Veterans Affairs Medical Centers of Brooklyn, New York 11203-2098, USA
J Clin Endocrinol Metab 88:516-23. 2003 - Bone metabolism and the cardiometabolic syndrome: pathophysiologic insightsSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, SUNY Downstate and Kings County Hospital Center, Brooklyn, NY 11203, USA
J Cardiometab Syndr 1:53-7. 2006.... - Antidiabetic medications and weight gain: implications for the practicing physicianSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, College of Medicine, SUNY Downstate Kings County Hospital Center, Brooklyn, NY 11203, USA
Curr Diab Rep 9:249-54. 2009..We also present the available therapeutic modalities that have the potential of achieving better glycemic control without adverse effects on body weight... - Control of cardiovascular risk factors in patients with diabetes and hypertension at urban academic medical centersSamy I McFarlane
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, State University of New York, Health Science Center at Brooklyn, Brooklyn, New York 11203, USA
Diabetes Care 25:718-23. 2002..CONCLUSIONS: Optimal control of CVD risk factors in adults with diabetes was achieved only in a minority of patients. Results reflect the inherent difficulties in achieving these complex guidelines in our present health care systems... - Challenges in the diagnosis and management of renal artery stenosisMoro O Salifu
Renal Fellowship Program, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 52, Brooklyn, NY, 11203, USA
Curr Hypertens Rep 7:219-27. 2005..Angioplasty and surgical interventions should be reserved for patients with preserved kidney size and hemodynamically significant stenosis...