M M Hussain

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. ncbi A proposed model for the assembly of chylomicrons
    M M Hussain
    Department of Biochemistry, School of Medicine, MCP Hahnemann University, Philadelphia, PA 19129, USA
    Atherosclerosis 148:1-15. 2000
  2. ncbi High affinity binding between lipoprotein lipase and lipoproteins involves multiple ionic and hydrophobic interactions, does not require enzyme activity, and is modulated by glycosaminoglycans
    M M Hussain
    Department of Biochemistry, School of Medicine, Medical College of Pennsylvania Hahnemann University, Philadelphia, Pennsylvania 19129, USA
    J Biol Chem 275:29324-30. 2000
  3. ncbi Signposts in the assembly of chylomicrons
    M M Hussain
    Departments of Anatomy and Cell Biology, and Pediatrics, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Front Biosci 6:D320-31. 2001
  4. ncbi Apolipoprotein B binding to microsomal triglyceride transfer protein decreases with increases in length and lipidation: implications in lipoprotein biosynthesis
    M M Hussain
    Department of Pathology, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania 19129, USA
    Biochemistry 36:13060-7. 1997
  5. ncbi Amino acids 430-570 in apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein
    M M Hussain
    Departments of Pathology and Biochemistry, Allegheny University of the Health Sciences, MCP Hahnemann School of Medicine, Philadelphia, Pennsylvania 19129, USA
    J Biol Chem 273:25612-5. 1998
  6. ncbi The mammalian low-density lipoprotein receptor family
    M M Hussain
    Department of Biochemistry, MCP Hahnemann University, Philadelphia, Pennsylvania 19129, USA
    Annu Rev Nutr 19:141-72. 1999
  7. ncbi Retinyl ester secretion by intestinal cells: a specific and regulated process dependent on assembly and secretion of chylomicrons
    N Nayak
    Department of Biochemistry, School of Medicine, MCP Hahnemann University, Philadelphia, PA 19129, USA
    J Lipid Res 42:272-80. 2001

Detail Information

Publications7

  1. ncbi A proposed model for the assembly of chylomicrons
    M M Hussain
    Department of Biochemistry, School of Medicine, MCP Hahnemann University, Philadelphia, PA 19129, USA
    Atherosclerosis 148:1-15. 2000
    ..The fusion of lipid droplets and primordial lipoproteins results in the formation of different size lipoproteins due to the 'core expansion' of the primordial lipoproteins...
  2. ncbi High affinity binding between lipoprotein lipase and lipoproteins involves multiple ionic and hydrophobic interactions, does not require enzyme activity, and is modulated by glycosaminoglycans
    M M Hussain
    Department of Biochemistry, School of Medicine, Medical College of Pennsylvania Hahnemann University, Philadelphia, Pennsylvania 19129, USA
    J Biol Chem 275:29324-30. 2000
    ..Moreover, we postulate that by binding to this cluster, GAGs modulate the association between LDL and LPL and the in vivo metabolism of LPL...
  3. ncbi Signposts in the assembly of chylomicrons
    M M Hussain
    Departments of Anatomy and Cell Biology, and Pediatrics, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Front Biosci 6:D320-31. 2001
    ..The knowledge about the molecular assembly of chylomicrons may lead to better therapeutic agents for controlling various hyperlipidemias, obesity, and atherosclerosis...
  4. ncbi Apolipoprotein B binding to microsomal triglyceride transfer protein decreases with increases in length and lipidation: implications in lipoprotein biosynthesis
    M M Hussain
    Department of Pathology, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania 19129, USA
    Biochemistry 36:13060-7. 1997
    ..It is proposed that steps in lipoprotein biosynthesis may be dictated by the sequential display of different functional domains on the apoB polypeptide...
  5. ncbi Amino acids 430-570 in apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein
    M M Hussain
    Departments of Pathology and Biochemistry, Allegheny University of the Health Sciences, MCP Hahnemann School of Medicine, Philadelphia, Pennsylvania 19129, USA
    J Biol Chem 273:25612-5. 1998
    ..These data indicate that B:430-570 in the alpha1-globular domain of apoB plays a crucial role in MTP binding and presumably in the initiation and maturation of apoB-containing lipoproteins...
  6. ncbi The mammalian low-density lipoprotein receptor family
    M M Hussain
    Department of Biochemistry, MCP Hahnemann University, Philadelphia, Pennsylvania 19129, USA
    Annu Rev Nutr 19:141-72. 1999
    ..It is anticipated that increased knowledge about the LDL-R family members will open new avenues for the treatment of many disorders...
  7. ncbi Retinyl ester secretion by intestinal cells: a specific and regulated process dependent on assembly and secretion of chylomicrons
    N Nayak
    Department of Biochemistry, School of Medicine, MCP Hahnemann University, Philadelphia, PA 19129, USA
    J Lipid Res 42:272-80. 2001
    ..We propose that RE are added to CM during final stages of lipoprotein assembly and may serve as signposts for these steps...