Research Topics
Species | M GromeierSummaryAffiliation: State University of New York Country: USA Publications
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Publications
Mechanism of injury-provoked poliomyelitisM Gromeier
Department of Molecular Genetics and Microbiology, School of Medicine, State University of New York at Stony Brook, Stony Brook, New York 11794, USA
J Virol 72:5056-60. 1998..The pathogenic mechanism of provocation poliomyelitis may differ from that of polio acquired in the absence of predisposing factors...
Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulenceM Gromeier
Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, New York 11794, USA
J Virol 73:958-64. 1999..We report that two adjacent stem loop structures within the IRES cooperatively determine neuropathogenicity...
Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitisM Gromeier
Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, New York 11790, USA
Virology 273:248-57. 2000..Expression of CD155 within embryonic structures giving rise to spinal cord anterior horn motor neurons may explain the restrictive host cell tropism of poliovirus for this cellular compartment of the CNS...
Genetic recombination of poliovirus in a cell-free systemR Duggal
Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, NY 11794 5222, USA
Proc Natl Acad Sci U S A 94:13786-91. 1997..The generation of poliovirus recombinants in a cell-free system offers new possibilities for studying recombination and evolution of RNA viruses...
Intergeneric poliovirus recombinants for the treatment of malignant gliomaM Gromeier
Department of Molecular Genetics and Microbiology, State University of New York, Stony Brook, NY 11794, USA
Proc Natl Acad Sci U S A 97:6803-8. 2000..Our observations suggest that highly attenuated poliovirus recombinants may have applicability as biotherapeutic antineoplastic agents...
