Research Topics
| Luther T ClarkSummaryAffiliation: State University of New York Country: USA Publications
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Detail Information
Publications
The epidemic of diabetes mellitus and the metabolic syndrome in African AmericansKeith C Ferdinand
Xavier University College of Pharmacy, Heartbeats Life Center, New Orleans, Louisiana, USA
Rev Cardiovasc Med 5:S28-33. 2004..Appropriate lifestyle modification programs, glucose control, and cardiovascular risk reduction therapy will reduce the excessive morbidity and mortality in this population...- Direct thrombin inhibitor use during percutaneous coronary interventionSpyros Kokolis
State University of New York Health Science Center at Brooklyn, Brooklyn, New York 11203, USA
J Cardiovasc Pharmacol 45:270-9. 2005..We review the pharmacological properties of these newer antithrombotic agents and evaluate the clinical data demonstrating their use in patients undergoing PCI... - Comparison of efficacy and safety of rosuvastatin versus atorvastatin in African-American patients in a six-week trialKeith C Ferdinand
Heartbeats Life Center, Xavier University College of Pharmacy, New Orleans, Louisiana, USA
Am J Cardiol 97:229-35. 2006..In conclusion, rosuvastatin 10 and 20 mg improved the overall lipid profile of hypercholesterolemic African-Americans better than did milligram-equivalent doses of atorvastatin... - Impact of completeness of percutaneous coronary intervention revascularization on long-term outcomes in the stent eraEdward L Hannan
State University of New York, University at Albany, Rensselaer, NY 12144 3456, USA
Circulation 113:2406-12. 2006.... - Home blood pressure monitoring in an ethnically diverse inner-city cardiology practiceGhazanfar Qureshi
Division of Cardiovascular Medicine, State University of New York, Downstate Medical Center, 450 Clarkson Ave, Brooklyn 11203 2098, USA
Ethn Dis 18:37-41. 2008..To evaluate home blood pressure monitoring (HBPM) in an inner city cardiology practice... - Vascular inflammation as a therapeutic target for prevention of cardiovascular diseaseLuther T Clark
Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Box 1199, Brooklyn, NY 11203, USA
Curr Atheroscler Rep 4:77-81. 2002 - Metabolic syndrome in African Americans: implications for preventing coronary heart diseaseLuther T Clark
Professor of Clinical Medicine, Chief, Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, Brooklyn, New York 11203, USA
Clin Cardiol 30:161-4. 2007..Although all components of the metabolic syndrome should be addressed, optimal control of atherogenic dyslipidemia and elevated blood pressure may reduce cardiovascular risk by more than 80%... - Issues in minority health: atherosclerosis and coronary heart disease in African AmericansLuther T Clark
Division of Cardiovascular Medicine, Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, New York 11203, USA
Med Clin North Am 89:977-1001, 994. 2005.... - Treating dyslipidemia with statins: the risk-benefit profileLuther T Clark
Division of Cardiovascular Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, USA
Am Heart J 145:387-96. 2003..Central to the pathogenesis of atherosclerosis are the deposition and retention of cholesterol in the arterial walls. Lipid modification, therefore, is key to CHD prevention... - Optimizing lipid lowering in patients at riskLuther T Clark
Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, Brooklyn, New York 11203 2098, USA
Clin Cardiol 27:III22-6. 2004..Several ongoing trials are evaluating whether the benefit of simultaneously blocking cholesterol synthesis and intestinal cholesterol absorption translates into better clinical outcomes... - Acute coronary syndromes in black Americans: is treatment different? Should it be?Luther T Clark
Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
Curr Cardiol Rep 7:249-54. 2005..Changing this and improving care for ACS in blacks requires better strategies for decreasing patient delays, earlier recognition and diagnosis of ACS, and more effective implementation of evidence-based treatment guidelines... - Usefulness of baseline plasma myeloperoxidase levels as an independent predictor of myocardial infarction at two years in patients presenting with acute coronary syndromeErdal Cavusoglu
Division of Cardiology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York, USA
Am J Cardiol 99:1364-8. 2007..34 ng/ml was 88% compared with 74% in those whose values were >20.34 ng/ml (p = 0.0249 by log-rank test). In conclusion, these data demonstrate that baseline MPO levels independently predict MI at 2 years in patients with ACS... - Usefulness of the white blood cell count as a predictor of angiographic findings in an unselected population referred for coronary angiographyErdal Cavusoglu
Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, USA
Am J Cardiol 98:1189-93. 2006.... - Low plasma RANTES levels are an independent predictor of cardiac mortality in patients referred for coronary angiographyErdal Cavusoglu
Division of Cardiology, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1257, Brooklyn, NY 11203 2098, USA
Arterioscler Thromb Vasc Biol 27:929-35. 2007..RANTES is a chemokine produced by a variety of cell types including platelets that has been implicated in atherosclerosis... - A risk score to predict in-hospital mortality for percutaneous coronary interventionsChuntao Wu
University at Albany, State University of New York, Albany, New York, USA
J Am Coll Cardiol 47:654-60. 2006..CONCLUSIONS: The risk score accurately predicted in-hospital death for PCI procedures using future New York data. Its performance in other patient populations needs to be further studied... - A comparison of mortality, myocardial infarction, and repeated revascularization for sirolimus-eluting and paclitaxel-eluting coronary stentsEdward L Hannan
School of Public Health, University at Albany, State University of New York, Albany, NY 12144 3456, USA
Am Heart J 154:545-53. 2007..There are only 2 approved devices: sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES). Only a few population-based studies have compared their patient outcomes... - Usefulness of the serum complement component C4 as a predictor of stroke in patients with known or suspected coronary artery disease referred for coronary angiographyErdal Cavusoglu
Division of Cardiology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York, USA
Am J Cardiol 100:164-8. 2007..In conclusion, in a cohort of men across a spectrum of risk referred for coronary angiography, a single baseline determination of serum complement C4 level is an independent predictor of the future development of stroke... - Adiponectin is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction in patients presenting with chest painErdal Cavusoglu
Division of Cardiology, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 1257, Brooklyn, NY 11203-2098, USA
Eur Heart J 27:2300-9. 2006..CONCLUSION: In a cohort of male patients undergoing coronary angiography, a single baseline determination of plasma adiponectin is independently predictive of the subsequent risk of death and MI... - Differences in utilization of drug-eluting stents by race and payerEdward L Hannan
University at Albany, State University of New York, Albany, NY, USA
Am J Cardiol 100:1192-8. 2007..93) and 0.85, 95% CI 0.75 to 0.96). In conclusion, African-Americans and low income groups receive DES less frequently than their counterparts compared with BMS. This is related to the hospitals where they are admitted, but not entirely... - Effects of alcoholism on coronary artery disease and left ventricular dysfunction in male veteransSpyros Kokolis
S.U.N.Y. Downstate Medical Center, Brooklyn, New York, USA
J Invasive Cardiol 18:304-7. 2006..There appears to be an inverse relationship between CAD and left ventricular function in patients with a history of heavy alcohol consumption... - Association of plasma levels of F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) with human atherosclerosisErdal Cavusoglu
Division of Cardiology, Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, New York 11203 2098, USA
J Am Coll Cardiol 50:1768-76. 2007..The purpose of this study was to determine the association of the F11 receptor (F11R) with human vascular disease... - Usefulness of anemia in men as an independent predictor of two-year cardiovascular outcome in patients presenting with acute coronary syndromeErdal Cavusoglu
Division of Cardiology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York, USA
Am J Cardiol 98:580-4. 2006..0065 by log-rank test). In conclusion, these data demonstrate that baseline anemia is a strong and independent predictor of death or AMI at 2 years in patients with ACS... - Impact of gender on in-hospital percutaneous coronary interventional outcomes in African-AmericansShyam Poludasu
Division of Cardiology, Department of Medicine, State University of New York, Downstate Medical Center, New York, USA
J Invasive Cardiol 19:123-8. 2007..The impact of gender on post-PCI outcomes in African-Americans has not been reported... - Tissue inhibitor of metalloproteinase-1 (TIMP-1) is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarctionErdal Cavusoglu
Department of Medicine, State University of New York Health Science Center, Brooklyn, NY 11203-2098, USA
Am Heart J 151:1101.e1-8. 2006..CONCLUSIONS: In a cohort of male patients undergoing coronary angiography, a single baseline determination of plasma TIMP-1 is independently predictive of the subsequent risk of death and MI... 
Obstructive sleep apnea and cardiovascular disease: role of the metabolic syndrome and its componentsGirardin Jean-Louis
Brooklyn Center for Health Disparities, SUNY Downstate Medical Center Brooklyn, NY 11203 2098, USA
J Clin Sleep Med 4:261-72. 2008..e., central obesity, hypertension, diabetes, and dyslipidemia). Large-scale, population-based studies testing causal models linking among sleep apnea, cardiovascular morbidity, and metabolic syndrome are needed...- Percutaneous coronary intervention in a patient with congenital factor XI deficiency and acquired inhibitorSudhir Mungee
Division of Cardiology, SUNY Downstate Medical Center, Brooklyn, NY 11203 2098, USA
Cardiology 107:69-72. 2007..Immunosuppressive therapy, plasma exchange and factor VII product transfusions have been used prior to cardiac interventions in few such reported cases... - Ethnic differences in achievement of cholesterol treatment goals. Results from the National Cholesterol Education Program Evaluation Project Utilizing Novel E-Technology IILuther T Clark
State University of New York Downstate Medical Center, Brooklyn, NY, USA
J Gen Intern Med 21:320-6. 2006..Additional research is needed to elucidate reasons for this disparity and to evaluate strategies for improving goal achievement among AA patients receiving therapy for dyslipidemia... - Bedside ultrasound diagnosis of aortic dissection in a cocaine abuserVijay Divakaran
State University of New York Downstate Medical Center, Brooklyn, NY, USA
Eur J Intern Med 18:595-6. 2007..This case report describes a patient with cocaine-induced myocardial infarction who was also found to have a type A aortic dissection. Interestingly, this potentially fatal complication was detected by a bedside 2D echocardiogram... - Changes in QT dispersion after thrombolysis for strokeJason Lazar
Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, Brooklyn, New York 11203 2098, USA
Int J Cardiol 125:258-62. 2008..Although largely studied in patients with cardiovascular disease, QTD is increased in acute stroke and this finding is an independent predictor of functional outcome and mortality following acute neurological events... - Ventricular arrhythmias and sudden cardiac deathSpyros Kokolis
Downstate Medical Center, State University of New York, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Prog Cardiovasc Dis 48:426-44. 2006 - Ethnic differences in electrocardiographic criteria for left ventricular hypertrophy: the LIFE study. Losartan Intervention For EndpointPeter M Okin
Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
Am J Hypertens 15:663-71. 2002..However, the high mortality associated with LVH in African American patients makes more accurate ECG detection of LVH in these patients a clinical priority... - Volume-outcome relationships for percutaneous coronary interventions in the stent eraEdward L Hannan
State University of New York, Albany, NY, USA
Circulation 112:1171-9. 2005..Most studies that are the basis of recommended volume thresholds for percutaneous coronary interventions (PCIs) predate the routine use of stent placement... - Anticoagulation strategies for patients undergoing percutaneous coronary intervention: unfractionated heparin, low-molecular-weight heparins, and direct thrombin inhibitorsSpyros Kokolis
State University of New York, Health Science Center at Brooklyn, 11203, USA
Prog Cardiovasc Dis 46:506-23. 2004..This paper reviews the pharmacologic properties of these newer antithrombotic agents and evaluates the clinical data demonstrating their use in patients undergoing PCI... - Relationship of lower extremity skin blood flow to the ankle brachial index in patients with peripheral arterial disease and normal volunteersKenneth E Otah
Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA
Int J Cardiol 103:41-6. 2005..94, p=0.001 for detecting PAD. Skin blood flow by this method correlates with the presence and severity of an abnormal ABI. This may offer a method of monitoring the effect of therapy and regression of peripheral atherosclerosis... - The metabolic syndrome: recognition and managementW Dallas Hall
Emory University School of Medicine, Atlanta, GA, USA
Dis Manag 9:16-33. 2006..Pharmacotherapy is typically needed for control of high blood pressure, hypercoagulability, and increased levels of blood glucose and triglycerides... - A summary of implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesScott M Grundy
Arterioscler Thromb Vasc Biol 24:1329-30. 2004 - Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesScott M Grundy
Circulation 110:227-39. 2004..Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy... - Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesScott M Grundy
Arterioscler Thromb Vasc Biol 24:e149-61. 2004..Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy... - Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group V: management of cardiovascular-renal complicationsRobert O Bonow
Circulation 105:e159-64. 2002 - Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III GuidelinesScott M Grundy
J Am Coll Cardiol 44:720-32. 2004..Finally, for people in lower-risk categories, recent clinical trials do not modify the goals and cutpoints of therapy... - Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Obesity, Metabolic Syndrome, and Hypertension Writing GroupSidney C Smith
Circulation 111:e134-9. 2005 - For the patient. What is the Metabolic Syndrome and why is it important?W Dallas Hall
Ethn Dis 13:546. 2003 - Task Force 6: coronary artery diseasePaul D Thompson
J Am Coll Cardiol 45:1348-53. 2005 - Results of the National Cholesterol Education (NCEP) Program Evaluation ProjecT Utilizing Novel E-Technology (NEPTUNE) II survey and implications for treatment under the recent NCEP Writing Group recommendationsMichael H Davidson
Radiant Development, Chicago, Illinois, USA
Am J Cardiol 96:556-63. 2005..Most of those (75%) with cardiovascular disease in NEPTUNE II would be considered very high risk and candidates for aggressive therapy to reach the new optional treatment goals... - Usefulness of an abnormal ankle-brachial index to predict presence of coronary artery disease in African-AmericansKenneth Ese Otah
Division of Cardiology, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
Am J Cardiol 93:481-3. 2004..However, a normal ABI did not predict absence of 1- or 2-vessel CAD. These results suggest that in this population, the ABI can be used to increase the pretest probability of severe CAD... - The Metabolic Syndrome in African Americans: a reviewW Dallas Hall
African American Lipid and Cardiovascular Council, USA
Ethn Dis 13:414-28. 2003..This comprehensive review is provided as part of the educational activities of the African-American Lipid and Cardiovascular Council (AALCC)...