John F Bruno

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. pmc Rapid detection and identification of a pathogen's DNA using Phi29 DNA polymerase
    Yun Xu
    Department of Medicine, T 16 Room 027, State University of New York at Stony Brook, Stony Brook, NY 11794 8154, USA
    Biochem Biophys Res Commun 375:522-5. 2008
  2. ncbi request reprint Detection of genetic diversity in linear plasmids 28-3 and 36 in Borrelia burgdorferi sensu stricto isolates by subtractive hybridization
    Yun Xu
    SUNY at Stony Brook, Department of Medicine, State University of New York at Stony Brook, T 15 Room 060, Stony Brook, NY 11794 8154, USA
    Microb Pathog 35:269-78. 2003
  3. doi request reprint Profiling the humoral immune response to Borrelia burgdorferi infection with protein microarrays
    Yun Xu
    Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
    Microb Pathog 45:403-7. 2008
  4. ncbi request reprint Identification of novel tick salivary gland proteins for vaccine development
    Yun Xu
    Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
    Biochem Biophys Res Commun 326:901-4. 2005
  5. pmc Genetic exchange and plasmid transfers in Borrelia burgdorferi sensu stricto revealed by three-way genome comparisons and multilocus sequence typing
    Wei Gang Qiu
    Department of Biological Sciences, Hunter College of the City University of New York, 695 Park Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 101:14150-5. 2004
  6. ncbi request reprint Co-evolution of the outer surface protein C gene (ospC) and intraspecific lineages of Borrelia burgdorferi sensu stricto in the northeastern United States
    Oliver Attie
    Department of Biological Sciences, Hunter College of the City University of New York, 695 Park Avenue, New York, NY 10021, United States
    Infect Genet Evol 7:1-12. 2007
  7. pmc Wide distribution of a high-virulence Borrelia burgdorferi clone in Europe and North America
    Wei Gang Qiu
    Hunter College of the City University of New York, New York, New York, USA
    Emerg Infect Dis 14:1097-104. 2008

Collaborators

Detail Information

Publications7

  1. pmc Rapid detection and identification of a pathogen's DNA using Phi29 DNA polymerase
    Yun Xu
    Department of Medicine, T 16 Room 027, State University of New York at Stony Brook, Stony Brook, NY 11794 8154, USA
    Biochem Biophys Res Commun 375:522-5. 2008
    ..This simple technology can ultimately be adapted as a sensitive method to detect specific DNA from both known and unknown pathogens in a wide variety of complex environments...
  2. ncbi request reprint Detection of genetic diversity in linear plasmids 28-3 and 36 in Borrelia burgdorferi sensu stricto isolates by subtractive hybridization
    Yun Xu
    SUNY at Stony Brook, Department of Medicine, State University of New York at Stony Brook, T 15 Room 060, Stony Brook, NY 11794 8154, USA
    Microb Pathog 35:269-78. 2003
    ..Therefore, these findings indicate that this genetic loci may participate in differentiating pathogens from non-pathogens and that its presence, which is correlated with ospC type, may play a role determining infectivity in humans...
  3. doi request reprint Profiling the humoral immune response to Borrelia burgdorferi infection with protein microarrays
    Yun Xu
    Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
    Microb Pathog 45:403-7. 2008
    ..This approach could contribute to a more rapid discovery of antigens not expressed in vitro that may be useful for the development of vaccine and diagnostics...
  4. ncbi request reprint Identification of novel tick salivary gland proteins for vaccine development
    Yun Xu
    Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794, USA
    Biochem Biophys Res Commun 326:901-4. 2005
    ..The protein products of these genes represent potential vaccine candidates for use in the control of ticks and to prevent transmission of tick-borne diseases...
  5. pmc Genetic exchange and plasmid transfers in Borrelia burgdorferi sensu stricto revealed by three-way genome comparisons and multilocus sequence typing
    Wei Gang Qiu
    Department of Biological Sciences, Hunter College of the City University of New York, 695 Park Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 101:14150-5. 2004
    ..Frequent recombination implies a potential for rapid adaptive evolution and a possible polygenic basis of B. burgdorferi pathogenicity...
  6. ncbi request reprint Co-evolution of the outer surface protein C gene (ospC) and intraspecific lineages of Borrelia burgdorferi sensu stricto in the northeastern United States
    Oliver Attie
    Department of Biological Sciences, Hunter College of the City University of New York, 695 Park Avenue, New York, NY 10021, United States
    Infect Genet Evol 7:1-12. 2007
    ..burgdorferi...
  7. pmc Wide distribution of a high-virulence Borrelia burgdorferi clone in Europe and North America
    Wei Gang Qiu
    Hunter College of the City University of New York, New York, New York, USA
    Emerg Infect Dis 14:1097-104. 2008
    ..We conclude that the ospC-A clone has dispersed rapidly and widely in the recent past. The spread of the ospC-A clone may have contributed, and likely continues to contribute, to the rise of Lyme disease incidence...