Peter J Bergold

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. doi Production of panic-like symptoms by lactate is associated with increased neural firing and oxidation of brain redox in the rat hippocampus
    Peter J Bergold
    Department of Physiology and Pharmacology, SUNY Downstate Medical Center, Brooklyn, NY 11203, United States
    Neurosci Lett 453:219-24. 2009
  2. doi Treatment of traumatic brain injury with anti-inflammatory drugs
    Peter J Bergold
    Robert F Furchgott Center for Neural Science, Department of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, United States Electronic address
    Exp Neurol 275:367-80. 2016
  3. pmc Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in rats
    Samah G Abdel Baki
    Departments of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America
    PLoS ONE 5:e12490. 2010
  4. ncbi Elevated lactate suppresses neuronal firing in vivo and inhibits glucose metabolism in hippocampal slice cultures
    Erin Gilbert
    Program in Neural and Behavioral Science, State University New York Downstate Medical Center, Brooklyn, NY 11203, USA
    Brain Res 1117:213-23. 2006
  5. doi Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury
    Margalit Haber
    Department of Physiology and Pharmacology, Robert F Furchgott Center for Neural and Behavioral Science, 450 Clarkson Avenue, Brooklyn, NY 11203, USA State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Exp Neurol 249:169-77. 2013
  6. doi Genomic analysis of ischemic preconditioning in adult rat hippocampal slice cultures
    Ethan A Benardete
    Department of Neurosurgery, SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
    Brain Res 1292:107-22. 2009
  7. doi A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats
    Samah G Abdel Baki
    Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
    Brain Res 1280:98-106. 2009
  8. doi Low-dose cardiotonic steroids increase sodium-potassium ATPase activity that protects hippocampal slice cultures from experimental ischemia
    Martin Oselkin
    Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Neurosci Lett 473:67-71. 2010
  9. pmc Reversible behavioral deficits in rats during a cycle of demyelination-remyelination of the fimbria
    Natalia M Grin'kina
    Robert F Furchgott Center for Neural Science, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America
    PLoS ONE 8:e53775. 2013
  10. doi Folate deficiency in rat pups during weaning causes learning and memory deficits
    Maria I Berrocal-Zaragoza
    Department of Medicine, State University New York SUNY Downstate Medical Center, Box 20, 450 Clarkson Avenue, Brooklyn, NY11203, USA
    Br J Nutr 112:1323-32. 2014

Collaborators

  • Pramod Dash
  • Nandor Ludvig
  • Diana Dow-Edwards
  • Samah G Abdel Baki
  • Natalia M Grin'kina
  • Margalit Haber
  • Erin Gilbert
  • Dezhi Tian
  • Maria I Berrocal-Zaragoza
  • Martin Oselkin
  • Andre A Fenton
  • Ethan A Benardete
  • Jeffrey M Sequeira
  • Michelle M Murphy
  • Edward V Quadros
  • Joan D Fernandez-Ballart
  • Alina Ershova
  • Raymond J Grill
  • Sara Orsi
  • Rachel Irizarry
  • Samah G Abdel-Baki
  • Ben Schwab
  • Hsin Yi Kao
  • Eduard Kelemen
  • Peter A Doris
  • Todd C Sacktor
  • John F Crary
  • Renata I Dmitrieva
  • Rachna Sondhi
  • J Michael Tang

Detail Information

Publications12

  1. doi Production of panic-like symptoms by lactate is associated with increased neural firing and oxidation of brain redox in the rat hippocampus
    Peter J Bergold
    Department of Physiology and Pharmacology, SUNY Downstate Medical Center, Brooklyn, NY 11203, United States
    Neurosci Lett 453:219-24. 2009
    ..These studies show that oxidation of brain redox and increased hippocampal firing are direct actions of lactate on the CNS that may contribute to the production of lactate-induced panic...
  2. doi Treatment of traumatic brain injury with anti-inflammatory drugs
    Peter J Bergold
    Robert F Furchgott Center for Neural Science, Department of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, United States Electronic address
    Exp Neurol 275:367-80. 2016
    ..The results of these preclinical studies and clinical trials are reviewed. Recommendations are suggested on how to improve preclinical testing of drugs to make them more relevant to evaluate for clinical trials. ..
  3. pmc Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in rats
    Samah G Abdel Baki
    Departments of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America
    PLoS ONE 5:e12490. 2010
    ..The drugs examined (minocycline (MINO), N-acetylcysteine (NAC), simvastatin, cyclosporine A, and progesterone) had FDA-approval for uses other than TBI and limited brain injury in experimental TBI models...
  4. ncbi Elevated lactate suppresses neuronal firing in vivo and inhibits glucose metabolism in hippocampal slice cultures
    Erin Gilbert
    Program in Neural and Behavioral Science, State University New York Downstate Medical Center, Brooklyn, NY 11203, USA
    Brain Res 1117:213-23. 2006
    ..ATP in slice culture was significantly increased by combination of glucose (1 mM) and lactate (1 mM). These data suggest that alteration of redox ratio underlies the suppression of neural discharge and glucose metabolism by lactate...
  5. doi Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury
    Margalit Haber
    Department of Physiology and Pharmacology, Robert F Furchgott Center for Neural and Behavioral Science, 450 Clarkson Avenue, Brooklyn, NY 11203, USA State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Exp Neurol 249:169-77. 2013
    ..This modulation of neuroinflammation may underlie the synergistic improvement in memory and set-shifting by the drug combination after mCCI...
  6. doi Genomic analysis of ischemic preconditioning in adult rat hippocampal slice cultures
    Ethan A Benardete
    Department of Neurosurgery, SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203, USA
    Brain Res 1292:107-22. 2009
    ..Our data thus suggests that changes in signaling pathways and their down-stream targets play an important role in triggering endogenous neuroprotection...
  7. doi A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats
    Samah G Abdel Baki
    Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
    Brain Res 1280:98-106. 2009
    ....
  8. doi Low-dose cardiotonic steroids increase sodium-potassium ATPase activity that protects hippocampal slice cultures from experimental ischemia
    Martin Oselkin
    Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Neurosci Lett 473:67-71. 2010
    ....
  9. pmc Reversible behavioral deficits in rats during a cycle of demyelination-remyelination of the fimbria
    Natalia M Grin'kina
    Robert F Furchgott Center for Neural Science, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America
    PLoS ONE 8:e53775. 2013
    ..These data suggest that active place avoidance is highly sensitive to white matter injury...
  10. doi Folate deficiency in rat pups during weaning causes learning and memory deficits
    Maria I Berrocal-Zaragoza
    Department of Medicine, State University New York SUNY Downstate Medical Center, Box 20, 450 Clarkson Avenue, Brooklyn, NY11203, USA
    Br J Nutr 112:1323-32. 2014
    ..Post-weaning folic acid supplementation did not correct these deficits. These observations indicate that folate deficiency during weaning affects postnatal development even when gestational folate supply is normal...
  11. ncbi Oxidation of 14C-labeled substrates by hippocampal slice cultures
    Erin Gilbert
    Program in Neural and Behavioral Science, State University New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, New York 11203, USA
    Brain Res Brain Res Protoc 15:135-41. 2005
    ..While the glucose oxidation rate saturated between 2.8 and 10 mM, lactate oxidation rate had not saturated at 10 mM. These data suggest that organotypic slice cultures provide a method to examine elements of cerebral metabolism in vitro...
  12. doi Protein kinase M zeta regulation of Na/K ATPase: a persistent neuroprotective mechanism of ischemic preconditioning in hippocampal slice cultures
    Dezhi Tian
    Program in Neural and Behavioral Science, The Robert F Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
    Brain Res 1213:127-39. 2008
    ..All three compounds blocked neuroprotection following ischemic preconditioning. PKMzeta levels were elevated 3 days after ischemic preconditioning. These data indicate key roles of PKMzeta and Na/K ATPase in ischemic preconditioning...