Research Topics
Genomes and GenesSpecies | Terry E GoldbergSummaryAffiliation: Stanley Medical Research Institute Country: USA Publications
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Publications
Neurophysiological correlates of age-related changes in working memory capacityVenkata S Mattay
Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
Neurosci Lett 392:32-7. 2006..As cognitive demand increases, however, they are pushed past a threshold beyond which physiological compensation cannot be made and, a decline in performance occurs...
Herpesviruses and Toxoplasma gondii in orbital frontal cortex of psychiatric patientsConcepcion Conejero-Goldberg
Stanley Brain Research Laboratory, Department of Psychiatry, Uniformed Services University of Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Schizophr Res 60:65-9. 2003..Additional studies including ones directed at the sensitive detection of viral nucleic acids in multiple brain regions should be directed at confirming or excluding a role for viruses and protozoa in the etiology of these disorders...
Infectious pathogen detection arrays: viral detection in cell lines and postmortem brain tissueConcepcion Conejero-Goldberg
Stanley Brain Research Laboratory, Clinical Center, National Institutes of Health, Bethesda, MD, USA
Biotechniques 39:741-51. 2005..This method may be used to provide evidence of viral infection in postmortem tissue from psychiatric patients as well as a wide range of other diagnostic categories...
Effect of catechol-O-methyltransferase val158met genotype on attentional controlGiuseppe Blasi
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1379, USA
J Neurosci 25:5038-45. 2005..These results indicate that met allele load and presumably enhanced dopaminergic tone improve the "efficiency" of local circuit processing within the cingulate cortex and thereby its function during AC...
Neural correlates of probabilistic category learning in patients with schizophreniaThomas W Weickert
Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health National Institutes of Health, Bethesda, Maryland 20892, USA
J Neurosci 29:1244-54. 2009....
The G72/G30 gene complex and cognitive abnormalities in schizophreniaTerry E Goldberg
Clinical Brain Disorders Branch, IRP, NIMH, NIH, Bethesda, MD, USA
Neuropsychopharmacology 31:2022-32. 2006..We present evidence that SNP variations in the G72 gene region increase risk of cognitive impairment in schizophrenia. SNP variations were not strongly associated with clinical diagnosis in family-based analyses...
Prefrontal electrophysiologic "noise" and catechol-O-methyltransferase genotype in schizophreniaGeorg Winterer
Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
Biol Psychiatry 60:578-84. 2006....
Age-related alterations in simple declarative memory and the effect of negative stimulus valenceVishnu P Murty
National Institutes of Health, Bethesda, MD, USA
J Cogn Neurosci 21:1920-33. 2009....
Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controlsCatherine M Diaz-Asper
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
Biol Psychiatry 63:72-9. 2008..Recently, other single nucleotide polymorphisms (SNPs) across the gene have emerged as additional risk factors for schizophrenia: namely rs737865, rs165599, and rs2097603. In a large sample, we examined whether these SNPs affect WM...
Differentiating allocation of resources and conflict detection within attentional control processingGiuseppe Blasi
National Institute of Mental Health, National Institutes of Health, Bethesda, MA, USA
Eur J Neurosci 25:594-602. 2007....
Brain regions underlying response inhibition and interference monitoring and suppressionGiuseppe Blasi
CBDB, GCAP, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Building 10, Center Drive, Bethesda, MD 20982-1379, USA
Eur J Neurosci 23:1658-64. 2006..These results extend previous findings by suggesting regional functional specialization within a cortical network supporting cognitive control...
Verbal and visual memory: characterizing the clinical and intermediate phenotype in schizophreniaShayna L Skelley
Clinical Brain Disorders Branch, 10 Center Drive, MSC 1379, National Institute of Mental Health NIH, Bethesda, MD 20892, USA
Schizophr Res 105:78-85. 2008..Schizophr Bull, 32(1), 179-194]. It remains unclear whether deficits lie in encoding or savings, and whether the deficit is heritable...
Catechol-O-methyltransferase Val158Met modulation of prefrontal-parietal-striatal brain systems during arithmetic and temporal transformations in working memoryHao Yang Tan
Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
J Neurosci 27:13393-401. 2007..These findings add to the integration of dopaminergic signaling in basic cortical assemblies with their roles in specific human brain networks during the orchestration of information processing in WM...
Modulatory effects of modafinil on neural circuits regulating emotion and cognitionRoberta Rasetti
Clinical Brain Disorders Branch Genes, Cognition, and Psychosis Program, NIMH, NIH, Bethesda, MD 20892, USA
Neuropsychopharmacology 35:2101-9. 2010....
Catechol-O-methyltransferase val108/158met genotype predicts working memory response to antipsychotic medicationsThomas W Weickert
National Institutes of Health, National Institute of Mental Health, Clinical Brain Disorders Branch, Building 10, Room 4C 101, MSC 1379, Bethesda, MD 20892, USA
Biol Psychiatry 56:677-82. 2004..The present study tested the effects of several COMT polymorphisms on the cognitive response to antipsychotic medication in patients with schizophrenia...
Prefrontal broadband noise, working memory, and genetic risk for schizophreniaGeorg Winterer
Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
Am J Psychiatry 161:490-500. 2004..In the present study, the authors explored whether this particular physiological abnormality predicts working memory performance and is related to the genetic risk for schizophrenia...
Tolcapone improves cognition and cortical information processing in normal human subjectsJose A Apud
Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20854, USA
Neuropsychopharmacology 32:1011-20. 2007..Our results are consistent with data from animal studies and from computational models of the effects of selective enhancement of DA signaling in the prefrontal cortex...
Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortexStefano Marenco
Genes and Cognition Program, Clinical Brain Disorders Branch, Intramural Research Program, Bldg 10, Rm 4S235, 10 Center Dr, NIMH, NIH, Bethesda, MD 20892, USA
Am J Psychiatry 163:740-2. 2006....
Relative risk of probabilistic category learning deficits in patients with schizophrenia and their siblingsThomas W Weickert
Genes, Cognition and Psychosis Program, Clinical, Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
Biol Psychiatry 67:948-55. 2010..There are also discrepant findings regarding probabilistic category learning acquisition rate and performance in patients with schizophrenia...
Set-shifting ability and schizophrenia: a marker of clinical illness or an intermediate phenotype?Alan E Ceaser
Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1379, USA
Biol Psychiatry 64:782-8. 2008....
Intra-dimensional/extra-dimensional set-shifting performance in schizophrenia: impact of distractorsSandra Jazbec
Clinical Brain Disorders Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
Schizophr Res 89:339-49. 2007....
First- and second-generation antipsychotic medication and cognitive processing in schizophreniaThomas W Weickert
Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Curr Psychiatry Rep 7:304-10. 2005..In particular, the catechol-O-methyltransferase val108/158met polymorphism has been shown to predict working memory improvement after administration of antipsychotic medication to patients with schizophrenia...
BDNF Val66Met polymorphism significantly affects d' in verbal recognition memory at short and long delaysTerry E Goldberg
Clinical Brain Disorders Branch, NIMH, Bethesda, MD 20892, USA
Biol Psychol 77:20-4. 2008..In sum, BDNF genotypes impacted "hits" in a recognition memory paradigm, findings consistent with the general notion that BDNF plays a prominent role in memory subprocesses thought to engage the medial temporal lobe...
Cognitive control and semantics in schizophrenia: an integrated approachJessica R Cohen
Clinical Brain Disorders Branch, National Institutes of Mental Health/NIH, Bldg. 10 Rm. 4S235, MSC 1379, Bethesda, MD 20892, USA
Am J Psychiatry 162:1969-71. 2005..CONCLUSIONS: Some aspects of the representation of semantic knowledge are preserved in schizophrenia, and patients use this information to control cognition in the same manner as healthy individuals...
Frontal release signs and cognition in people with schizophrenia, their siblings and healthy controlsThomas M Hyde
Clinical Brain Disorders Branch, Intramural Research Program, National Institutes of Health, 10 Center Drive, Bethesda, Maryland 20892, USA
Br J Psychiatry 191:120-5. 2007..Frontal release signs, a subset of neurological soft signs, are common in schizophrenia...
Cognitive factor structure and invariance in people with schizophrenia, their unaffected siblings, and controlsDwight Dickinson
National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Schizophr Bull 37:1157-67. 2011..Furthermore, we tested the hypothesis that cognitive performance in schizophrenia is more generalized across domains than among siblings and controls...
Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophreniaMichael F Egan
Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health NIH DHHS, Building 10, Center Drive, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 101:12604-9. 2004..These convergent data point to a specific molecular pathway by which GRM3 genotype alters glutamate neurotransmission, prefrontal and hippocampal physiology and cognition, and thereby increased risk for schizophrenia...
Neurophysiological correlates of age-related changes in working memory updatingJamie E Podell
Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA
Neuroimage 62:2151-60. 2012..These results are consistent with computational models of executive cognition and dopamine-mediated age-related cognitive decline...
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophreniaJoseph H Callicott
Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, Division of Intramural Research, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 102:8627-32. 2005....
Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeuticsCatherine M Diaz-Asper
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
NeuroRx 3:97-105. 2006..Haplotype effects also may account for a modest percentage of the variance in test performance, and are an important area for future study...
Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS)Richard S E Keefe
Department of Psychiatry, Box 3207, Duke University Medical Center, Durham, North Carolina 27710, USA
Schizophr Res 102:108-15. 2008..An education-correction factor was calculated and recommended only for non-schizophrenia patients. Eight different verbal memory tests were found to have equivalent levels of difficulty...
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophreniaStephen J Huffaker
Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland, USA
Nat Med 15:509-18. 2009..These results identify a previously undescribed KCNH2 channel isoform involved in cortical physiology, cognition and psychosis, providing a potential new therapeutic drug target...
Amygdala activation in affective priming: a magnetoencephalogram studyMaite Garolera
Clinical Brain Disorders Branch, IRPP NIMH NIH DHHS, Bethesda, Maryland, USA
Neuroreport 18:1449-53. 2007..This study provides evidence for theta power changes in the amygdala and demonstrates that the analysis of brain oscillations provides a powerful tool to explore mechanisms implicated in emotional processing...
Neural mechanisms underlying probabilistic category learning in normal agingFrancesco Fera
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
J Neurosci 25:11340-8. 2005....
Genes and the parsing of cognitive processesTerry E Goldberg
Clinical Brain Disorders Branch, GCAPP, IRP, NIMH, NIH, Bethesda, MD 20892, USA
Trends Cogn Sci 8:325-35. 2004..As such it may be necessary to view cognition in novel ways, based on constraints imposed by genomics and neurobiology, in order to increase the effect size of genotypic influences on cognition...
Neurobiology of cognitive aging: insights from imaging geneticsVenkata S Mattay
Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Biol Psychol 79:9-22. 2008..Further, it is likely with early identification of susceptible individuals, early intervention through life-style changes and other methods could increase an individual's resilience to the effects of aging...
Lack of false recognition in schizophrenia: a consequence of poor memory?Brita Elvevåg
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4S235, MSC 1379, Bethesda, MD 20892, USA
Neuropsychologia 42:546-54. 2004..We conclude that despite poor memory, patients with schizophrenia are not especially susceptible to interference from previous tasks and are not particularly prone to false recollections...
Functional and effective frontotemporal connectivity and genetic risk for schizophreniaGeorg Winterer
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
Biol Psychiatry 54:1181-92. 2003..The reasons why frontotemporal connectivity appears to be a poor predictor of genetic risk for schizophrenia are discussed...
Identification of tone duration, line length, and letter position: an experimental approach to timing and working memory deficits in schizophreniaBrita Elvevåg
Clinical Brain Disorders Branch, National Institute of Mental Health National Institutes of Health, Building 10, Rm 4S235, Building 10, MSC 1379, Bethesda, MD 20892, USA
J Abnorm Psychol 113:509-21. 2004..These findings do not support the notion of a global impairment in absolute identification in schizophrenia. However, the authors suggest that some aspect of temporal information processing is indeed disturbed in schizophrenia...
Letter and category fluency in schizophrenic patients: a meta-analysisChristina E Bokat
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Room 4s 235, 10 Center Drive MSC 1379, Bethesda, MD 20892, USA
Schizophr Res 64:73-8. 2003....
The MATRICS consensus cognitive battery in patients with bipolar I disorderKatherine E Burdick
Department of Psychiatry, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Neuropsychopharmacology 36:1587-92. 2011..Additional studies should address important psychometric features such as repeatability and potential practice and/or ceiling effects...
A meta-analysis and critical review of the effects of conventional neuroleptic treatment on cognition in schizophrenia: opening a closed bookAaron L Mishara
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
Biol Psychiatry 55:1013-22. 2004..Given unavoidable methodologic limitations of the primary studies, current findings suggest that the impact of conventional medication on cognitive function should be re-evaluated...
Imaging genetic influences in human brain functionVenkata S Mattay
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Building 10, Center Drive, Room 4S-235, Bethesda, MD 20892-1379, USA
Curr Opin Neurobiol 14:239-47. 2004..The results also show that neuroimaging techniques can elucidate the influence of genes on brain function in relatively small sample populations, sometimes even in the absence of significant differences in behavioral measures...
Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophreniaTerry E Goldberg
Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Arch Gen Psychiatry 60:889-96. 2003..Cognitive dysfunction in the working memory domain seems to be under genetic control and is a candidate intermediate phenotype in schizophrenia. Genes that affect working memory processing may contribute to risk for schizophrenia...
Dissociating the effects of Sternberg working memory demands in prefrontal cortexMario Altamura
Department of Biomedical Sciences, Psychiatry Unit, University of Foggia, Italy
Psychiatry Res 154:103-14. 2007..These results suggest the possibility that top-down modulation of attention or cognitive control at encoding and/or decisionmaking may be mediated by these areas...
Autobiographical memory in schizophrenia: an examination of the distribution of memoriesBrita Elvevåg
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
Neuropsychology 17:402-9. 2003..It was concluded that patients' paucity of memories generated from the recent decade reflects encoding or acquisition problems, which may be associated with the illness period...
Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confoundsThomas W Weickert
Clinical Brain Disorders Branch, National Institute of Mental Health NIH, Building 10 Room 4N202, MSC 1379, Bethesda, MD 20892, USA
Neuropsychopharmacology 28:1491-500. 2003..These findings suggest that relative to placebo withdrawal, atypicals improve cognitive performance in SC. However, this finding may not be specific to atypicals, since analogous studies of typicals have not been performed...
Working memory deficits and levels of N-acetylaspartate in patients with schizophreniform disorderAlessandro Bertolino
Department of Psychiatry and Neurological Sciences, University of Bari, Italy
Am J Psychiatry 160:483-9. 2003..In addition, they assessed the relationship between N-acetylaspartate levels and working memory deficits...
Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical inputThomas W Weickert
Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
Learn Mem 9:430-42. 2002..The abnormal performance offset between patients with schizophrenia and controls in the absence of learning rate differences suggests that abnormal cortical processing provides altered input to normal striatal circuitry...
Probed recall for serial order deficits in short-term memory in schizophrenic patientsBrita Elvevåg
Clinical Brain Disorders Branch, National Institute of Mental Health National Institutes of Health, Room 4S235, MSC 1379, Building 10, Bethesda, MD 20892, USA
Schizophr Res 59:127-35. 2003..If this is the case, we predicted that the group difference in the terminal positions could be eliminated through the use of a probed recall paradigm...
The phonological similarity effect in short-term memory serial recall in schizophreniaBrita Elvevåg
Clinical Brain Disorders Branch, National Institute of Mental Health National Institutes of Health, Building 10, Room 4S235 MSC 1379, Bethesda, MD 20892, USA
Psychiatry Res 112:77-81. 2002..e. order) errors with phonologically similar lists of items. We conclude that patients with schizophrenia employ recall strategies for phonologically similar items in short-term memory that are equivalent to those of healthy controls...
Intermediate cognitive phenotypes associated with schizophreniaMichael F Egan
Brain Disorders Branch, NIMH, Bethesda, MD, USA
Methods Mol Med 77:163-97. 2003
Left inferior prefrontal cortex activation during a semantic decision-making task predicts the degree of semantic organizationAlan Simmons
Laboratory of Biological Dynamics and Theoretical Medicine, University of California San Diego, La Jolla, 92093-0603, USA
Neuroimage 28:30-8. 2005..This finding is consistent with the role of the IPFC in establishing self-generated semantic relationships between stimuli...
Genetic variation in the DAOA gene complex: impact on susceptibility for schizophrenia and on cognitive performanceCarolin Opgen-Rhein
Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, United States
Schizophr Res 103:169-77. 2008..Our aim in this study was to investigate the relationship between DAOA variation and schizophrenia, and the influence of DAOA on cognitive performance...
Levels of processing effects on recognition memory in patients with schizophreniaBrianna M Paul
Clinical Brain Disorders Branch, National Institute of Mental Health, 10 Center Drive, MSC 1379, Bethesda MD 20892, USA
Schizophr Res 74:101-10. 2005..It also suggests that strategies that place constraints on the encoding processes used by patients may help improve the efficiency with which they learn and remember information...
Quantifying incoherence in speech: an automated methodology and novel application to schizophreniaBrita Elvevåg
Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda MD, United States
Schizophr Res 93:304-16. 2007..In conclusion, LSA can be used to assay disordered language production so as to both complement human clinical ratings as well as experimentally parse this incoherence in a theory-driven manner...
Factor analysis of neurocognitive tests in a large sample of schizophrenic probands, their siblings, and healthy controlsMargo R Genderson
Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, NIH, 10 Center Drive, CRC 7 5342, Bethesda, MD 20892, United States
Schizophr Res 94:231-9. 2007..Furthermore, these findings provide the first confirmation that cognitive structure is comparable in family members of schizophrenia patients, as well as in patients themselves and controls...
Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case seriesStefano Marenco
Intramural Research Program, Clinical Brain Disorders Branch, National Institute of Mental Health, Building 10, Room 4S235, Bethesda, MD 20892, USA
Schizophr Res 57:221-6. 2002..No clear improvement in psychosis or in cognition was observed over the course of the study. CX516 at the doses tested did not appear to yield dramatic effects as a sole agent, but inference from this study is limited...
The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive batteryRichard S E Keefe
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, P O Box 3270, Durham, NC 27710, USA
Schizophr Res 68:283-97. 2004..76) and healthy controls (r=0.90). These psychometric properties make the BACS a promising tool for assessing cognition repeatedly in patients with schizophrenia, especially in clinical trials of cognitive enhancement...
DTNBP1 genotype influences cognitive decline in schizophreniaKatherine E Burdick
Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, United States
Schizophr Res 89:169-72. 2007..The current study assessed the relationship between intellectual decline in schizophrenia and genetic variation in dysbindin-1 (DTNBP1)...
Reduced parahippocampal connectivity produces schizophrenia-like memory deficits in simulated neural circuits with reduced parahippocampal connectivityLucia M Talamini
Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
Arch Gen Psychiatry 62:485-93. 2005....
Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteriaMichael F Green
Neuropsychiatric Institute, Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA
Biol Psychiatry 56:301-7. 2004..The results from this meeting constitute the initial steps for reaching a consensus cognitive battery for clinical trials in schizophrenia...
COMT genotype and manic symptoms in schizophreniaPamela DeRosse
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States
Schizophr Res 87:28-31. 2006..These data suggest that the effect of COMT variation may be associated with comorbid manic symptoms in SZ...
Identification of separable cognitive factors in schizophreniaKeith H Nuechterlein
Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, USA
Schizophr Res 72:29-39. 2004..These separable cognitive dimensions also have broader relevance to future research aimed at understanding the nature and structure of core cognitive deficits in schizophrenia...
Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect?Terry E Goldberg
Zucker Hillside Hospital, 7559 263rd Street, Glen Oaks, NY 11004, USA
Arch Gen Psychiatry 64:1115-22. 2007..However, none of these studies included healthy controls undergoing repeated testing to assess the possibility that improvements might reflect simple practice effects...
