Lei Zhu

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Modulator design for x-ray scatter correction using primary modulation: material selection
    Hewei Gao
    Department of Radiology, Stanford University, California 94305, USA
    Med Phys 37:4029-37. 2010
  2. pmc Noise suppression in scatter correction for cone-beam CT
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 36:741-52. 2009
  3. pmc Search for IMRT inverse plans with piecewise constant fluence maps using compressed sensing techniques
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 36:1895-905. 2009
  4. doi request reprint Using total-variation regularization for intensity modulated radiation therapy inverse planning with field-specific numbers of segments
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    Phys Med Biol 53:6653-72. 2008
  5. pmc Scatter correction for cone-beam CT in radiation therapy
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 36:2258-68. 2009
  6. ncbi request reprint Scatter correction method for X-ray CT using primary modulation: theory and preliminary results
    Lei Zhu
    Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
    IEEE Trans Med Imaging 25:1573-87. 2006
  7. pmc Scatter correction method for x-ray CT using primary modulation: phantom studies
    Hewei Gao
    Department of Radiology, Stanford University, Stanford, California 94305, USA
    Med Phys 37:934-46. 2010
  8. pmc Toward truly optimal IMRT dose distribution: inverse planning with voxel-specific penalty
    Pavel Lougovski
    Department of Radiation Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA 94305 5847
    Technol Cancer Res Treat 9:629-36. 2010
  9. doi request reprint Noise reduction in low-dose x-ray fluoroscopy for image-guided radiation therapy
    Jing Wang
    Department of Radiation Oncology, Stanford University School of Medicine, CA 94305, USA
    Int J Radiat Oncol Biol Phys 74:637-43. 2009
  10. pmc Compressed sensing based cone-beam computed tomography reconstruction with a first-order method
    Kihwan Choi
    Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA
    Med Phys 37:5113-25. 2010

Collaborators

Detail Information

Publications22

  1. pmc Modulator design for x-ray scatter correction using primary modulation: material selection
    Hewei Gao
    Department of Radiology, Stanford University, California 94305, USA
    Med Phys 37:4029-37. 2010
    ..In the practical implementation, beam hardening of the modulator blocker is a limiting factor because it causes inconsistency in the primary signal and therefore degrades the accuracy of scatter correction...
  2. pmc Noise suppression in scatter correction for cone-beam CT
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 36:741-52. 2009
    ..6. Significant image quality improvement is also shown in the results on an anthropomorphic phantom, in which the global noise level is reduced and the local streaking artifacts around bones are suppressed...
  3. pmc Search for IMRT inverse plans with piecewise constant fluence maps using compressed sensing techniques
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 36:1895-905. 2009
    ..With the focus on the sparsity of the optimal solution, the proposed method is distinct from the existing beamlet- or segment-based optimization algorithms...
  4. doi request reprint Using total-variation regularization for intensity modulated radiation therapy inverse planning with field-specific numbers of segments
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
    Phys Med Biol 53:6653-72. 2008
    ..The head and neck result is also compared to that using an equal number of four segments for each field. The comparison shows that using field-specific numbers of segments achieves a much improved dose distribution...
  5. pmc Scatter correction for cone-beam CT in radiation therapy
    Lei Zhu
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 36:2258-68. 2009
    ..7% to 5.4%. The proposed method is attractive in applications where a high CBCT image quality is critical, for example, dose calculation in adaptive radiation therapy...
  6. ncbi request reprint Scatter correction method for X-ray CT using primary modulation: theory and preliminary results
    Lei Zhu
    Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
    IEEE Trans Med Imaging 25:1573-87. 2006
    ..Although the proposed scatter correction technique was implemented for X-ray CT, it can also be used in other X-ray imaging applications, as long as a primary modulator can be inserted between the X-ray source and the imaged object...
  7. pmc Scatter correction method for x-ray CT using primary modulation: phantom studies
    Hewei Gao
    Department of Radiology, Stanford University, Stanford, California 94305, USA
    Med Phys 37:934-46. 2010
    ..In this work, the authors provide a quantitative evaluation of the primary modulation technique and demonstrate its performance in applications where scatter correction is more challenging...
  8. pmc Toward truly optimal IMRT dose distribution: inverse planning with voxel-specific penalty
    Pavel Lougovski
    Department of Radiation Oncology, Stanford University School of Medicine, 875 Blake Wilbur Drive, Stanford, CA 94305 5847
    Technol Cancer Res Treat 9:629-36. 2010
    ..To establish an inverse planning framework with adjustable voxel penalty for more conformal IMRT dose distribution as well as improved interactive controllability over the regional dose distribution of the resultant plan...
  9. doi request reprint Noise reduction in low-dose x-ray fluoroscopy for image-guided radiation therapy
    Jing Wang
    Department of Radiation Oncology, Stanford University School of Medicine, CA 94305, USA
    Int J Radiat Oncol Biol Phys 74:637-43. 2009
    ..To improve the quality of low-dose X-ray fluoroscopic images using statistics-based restoration algorithm so that the patient fluoroscopy can be performed with reduced radiation dose...
  10. pmc Compressed sensing based cone-beam computed tomography reconstruction with a first-order method
    Kihwan Choi
    Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA
    Med Phys 37:5113-25. 2010
    ..This article considers the problem of reconstructing cone-beam computed tomography (CBCT) images from a set of undersampled and potentially noisy projection measurements...
  11. pmc Inverse planning for IMRT with nonuniform beam profiles using total-variation regularization (TVR)
    Taeho Kim
    Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA
    Med Phys 38:57-66. 2011
    ..The authors propose a total-variation regularization (TVR)-based formalism by taking the inherent shapes of incident beam profiles into account...
  12. ncbi request reprint A short-scan reconstruction for cone-beam CT using shift-invariant FBP and equal weighting
    Lei Zhu
    Electrical Engineering and Radiology, Stanford University, Stanford, California 94305, USA
    Med Phys 34:4422-38. 2007
    ..Due to its shift-invariant filtered-backprojection structure, the proposed algorithm is implemented efficiently, and requires a simple adaptation of the FDK algorithm...
  13. pmc Three-dimensional anisotropic adaptive filtering of projection data for noise reduction in cone beam CT
    Andreas Maier
    Department of Radiology, Stanford University, Stanford, CA 94305, USA
    Med Phys 38:5896-909. 2011
    ..By applying the filtering prior to 3D reconstruction, noise-induced streak artifacts are reduced as compared to processing in the image domain...
  14. doi request reprint Spontaneous decay of CdSe/ZnS core-shell quantum dots at the air-dielectric interface
    Lei Zhu
    Department of Electrical Engineering, University of Texas at Arlington, 416 Yates St, Arlington, Texas 76019, USA
    Opt Express 20:3144-51. 2012
    ..The results suggest that, by embedding the quantum dots into a high-index dielectric material, one can reduce the spontaneous decay time to sub-nanosecond scale while preserving high quantum efficiency...
  15. ncbi request reprint On simulating subjective evaluation using combined objective metrics for validation of 3D tumor segmentation
    Xiang Deng
    Corporate Technology, Siemens Ltd, China
    Med Image Comput Comput Assist Interv 10:977-84. 2007
    ..Our method has the potential to facilitate the development of new tumor segmentation algorithms and assist large scale segmentation evaluation studies...
  16. pmc Harmonic skeleton guided evaluation of stenoses in human coronary arteries
    Yan Yang
    Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Med Image Comput Comput Assist Interv 8:490-7. 2005
    ....
  17. ncbi request reprint Region competition based active contour for medical object extraction
    Yanfeng Shang
    Institute of Image Processing and Pattern Recognition, Shanghai Jiaotong University, Shanghai 200240, PR China
    Comput Med Imaging Graph 32:109-17. 2008
    ..As the results show, the algorithm is fast, convergent, adapted to a broad range of medical objects and produces satisfactory results...
  18. pmc An image morphing technique based on optimal mass preserving mapping
    Lei Zhu
    Department of Biomedical Engineering and the School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA
    IEEE Trans Image Process 16:1481-95. 2007
    ..This proposed morphing method is also extended to doubly connected domains using a harmonic parameterization technique, along with finite-element methods...
  19. pmc SPIDer: Saccharomyces protein-protein interaction database
    Xiaomei Wu
    MOE Key Laboratory for Biodiversity Science and Ecological Engineering and College of Life Sciences, Beijing Normal University, Beijing 100875, China
    BMC Bioinformatics 7:S16. 2006
    ..Solely derived from the Gene Ontology (GO), we have defined an effective method of reconstructing a yeast protein interaction network by measuring relative specificity similarity (RSS) between two GO terms...
  20. ncbi request reprint An initial strategy for comparing proteins at the domain architecture level
    Kui Lin
    MOE Key Laboratory for Biodiversity Science and Ecological Engineering and College of Life Sciences, Beijing Normal University, Beijing 100875, China
    Bioinformatics 22:2081-6. 2006
    ..By combining three different indices, the Jaccard index, the Goodman-Kruskal gamma function and the domain duplicate index, into a single similarity measure, we propose a method for comparing proteins based on their domain architectures...
  21. pmc Mass preserving registration for heart MR images
    Lei Zhu
    School of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Med Image Comput Comput Assist Interv 8:147-54. 2005
    ..It assumes an underlining continuum model, in which the total amount of mass is exactly preserved during the transformation of tissues. We use a finite element approach to numerically implement the algorithm...
  22. pmc Flattening maps for the visualization of multibranched vessels
    Lei Zhu
    Schools of Biomedical and Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
    IEEE Trans Med Imaging 24:191-8. 2005
    ..This approach employs the theory of optimal mass transport. Furthermore, a new way of extracting center lines for vessel fly-throughs is provided...