Hui Zhao

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Regulation of maternal and fetal hemodynamics by heme oxygenase in mice
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Biol Reprod 78:744-51. 2008
  2. pmc Maternal heme oxygenase 1 regulates placental vasculature development via angiogenic factors in mice
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Biol Reprod 85:1005-12. 2011
  3. ncbi request reprint Expression and regulation of heme oxygenase isozymes in the developing mouse cortex
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Pediatr Res 60:518-23. 2006
  4. pmc Effect of heme oxygenase-1 deficiency on placental development
    H Zhao
    Dept of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Placenta 30:861-8. 2009
  5. ncbi request reprint The potential Salmonella aroA- vaccine strain is safe and effective in young BALB/c mice
    Stacy M Burns-Guydish
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Neonatology 91:114-20. 2007
  6. pmc Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model
    Stephanie Schulz
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Physiol Gastrointest Liver Physiol 304:G991-G1001. 2013
  7. ncbi request reprint Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo
    Hui Zhao
    Stanford University School of Medicine, Department of Pediatrics, Stanford, California 94305 5427, USA
    J Biomed Opt 10:41210. 2005
  8. ncbi request reprint Effect of light exposure on metalloporphyrin-treated newborn mice
    Stephanie Schulz
    Department of Pediatrics, Stanford University School of Medicine, California, USA
    Pediatr Res 72:161-8. 2012
  9. ncbi request reprint Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1
    Weisheng Zhang
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University Medical Center, Stanford University, Stanford, CA 94305 5208, USA
    J Mol Med (Berl) 80:655-64. 2002
  10. pmc Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors
    Yu An Cao
    Departments of Pediatrics, Stanford University School of Medicine, CA, USA
    Blood 112:4494-502. 2008

Collaborators

Detail Information

Publications46

  1. ncbi request reprint Regulation of maternal and fetal hemodynamics by heme oxygenase in mice
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Biol Reprod 78:744-51. 2008
    ....
  2. pmc Maternal heme oxygenase 1 regulates placental vasculature development via angiogenic factors in mice
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Biol Reprod 85:1005-12. 2011
    ..These results implied that Hmox1 polymorphisms among the human population might contribute to some unexplained cases of pregnancy disorders, such as fetal growth retardation and preeclampsia...
  3. ncbi request reprint Expression and regulation of heme oxygenase isozymes in the developing mouse cortex
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Pediatr Res 60:518-23. 2006
    ..Therefore, we conclude that HO-1 gene expression in the cortex is developmentally-regulated and that methylation of the HO-1 CpG island is not associated with the down-regulation of the gene...
  4. pmc Effect of heme oxygenase-1 deficiency on placental development
    H Zhao
    Dept of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Placenta 30:861-8. 2009
    ..We conclude that a partial deficiency in HO-1 is associated with morphological changes in the placenta and elevations in maternal diastolic blood pressure and plasma sFlt-1 levels, despite a compensatory increase in HO-2 expression...
  5. ncbi request reprint The potential Salmonella aroA- vaccine strain is safe and effective in young BALB/c mice
    Stacy M Burns-Guydish
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Neonatology 91:114-20. 2007
    ..Due to the increased susceptibility of neonates to pathogens including those with mutations, the use of live vaccine strategies in the human population may present a potential risk to the young...
  6. pmc Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model
    Stephanie Schulz
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Physiol Gastrointest Liver Physiol 304:G991-G1001. 2013
    ..We conclude that a partial HO-1 deficiency promotes experimental NEC-like intestinal injury, possibly mediated by exaggerated inflammation and disruption in tissue repair...
  7. ncbi request reprint Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo
    Hui Zhao
    Stanford University School of Medicine, Department of Pediatrics, Stanford, California 94305 5427, USA
    J Biomed Opt 10:41210. 2005
    ..These spectral measurement data allow for improved understanding of how these reporters can be used in vivo and what they can reveal about biological processes in living subjects...
  8. ncbi request reprint Effect of light exposure on metalloporphyrin-treated newborn mice
    Stephanie Schulz
    Department of Pediatrics, Stanford University School of Medicine, California, USA
    Pediatr Res 72:161-8. 2012
    ..Here, we investigated possible photosensitizing effects of chromium mesoporphyrin (CrMP) and zinc deuteroporphyrin bis-glycol (ZnBG)...
  9. ncbi request reprint Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1
    Weisheng Zhang
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University Medical Center, Stanford University, Stanford, CA 94305 5208, USA
    J Mol Med (Berl) 80:655-64. 2002
    ..Among the known inhibitors of HO enzyme activity that were evaluated in this study, ZnBG did not significantly affect HO-1 transcription and therefore may be well suited for the prevention of neonatal jaundice...
  10. pmc Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors
    Yu An Cao
    Departments of Pediatrics, Stanford University School of Medicine, CA, USA
    Blood 112:4494-502. 2008
    ..Control of stem cell stress response by HO-1 presents opportunities for metabolic manipulation of stem cell-based therapies...
  11. pmc Effects of zinc deuteroporphyrin bis glycol on newborn mice after heme loading
    Cynthia X He
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA
    Pediatr Res 70:467-72. 2011
    ..We conclude that ZnBG may be an attractive compound for treating severe neonatal hyperbilirubinemia caused by hemolytic disease...
  12. ncbi request reprint Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals
    Hui Zhao
    Stanford University School of Medicine, USA
    Mol Imaging 3:43-54. 2004
    ....
  13. pmc The role of Bach1 in the induction of heme oxygenase by tin mesoporphyrin
    Aida Abate
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Rm S 230, Stanford, CA 94305, USA
    Biochem Biophys Res Commun 354:757-63. 2007
    ..In conclusion, SnMP induces HO-1 expression not only by de-repressing the HO-1 promoter by binding Bach1, but also by accelerating Bach1 degradation...
  14. doi request reprint A deficiency in haem oxygenase-1 induces foetal growth restriction by placental vasculature defects
    Ronald J Wong
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Acta Paediatr 101:827-34. 2012
    ....
  15. ncbi request reprint Monitoring age-related susceptibility of young mice to oral Salmonella enterica serovar Typhimurium infection using an in vivo murine model
    Stacy M Burns-Guydish
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Pediatr Res 58:153-8. 2005
    ..Thus, this model of age-related susceptibility to S. typhimurium using BLI can be used to advance our understanding of the mechanisms involved in newborn susceptibility to infection...
  16. doi request reprint Infection of pregnant mice with Listeria monocytogenes induces fetal bradycardia
    Jonathan Hardy
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
    Pediatr Res 71:539-45. 2012
    ..However, pregnant women who get infected with Listeria may experience only mild symptoms, making the diagnosis difficult, even when the fetus is fatally infected...
  17. pmc Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death
    Hong D Xiao
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA
    Am J Pathol 165:1019-32. 2004
    ..In conclusion, increased local production of angiotensin II in the heart is not sufficient to induce ventricular hypertrophy or fibrosis. Instead, it leads to atrial morphological changes, cardiac arrhythmia, and sudden death...
  18. pmc Visualization of Proteus mirabilis within the matrix of urease-induced bladder stones during experimental urinary tract infection
    Xin Li
    Department of Microbiology and Immunology, University of Maryland School of Medicine, Veterans Affairs Medical Center, Baltimore, Maryland 21201, USA
    Infect Immun 70:389-94. 2002
    ..mirabilis within the urease-induced stone matrix. Alizarin red S staining was used to detect calcium-containing deposits in bladder and kidney tissues of P. mirabilis-infected mice...
  19. doi request reprint Flow cytometric characterization of T lymphocyte subsets in the peripheral blood of Chinese rhesus macaques: normal range, age- and sex-related differences
    Chen Li Qiu
    State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, China CDC, 27 Nanwei Road, Xuanwu District, Beijing 100050, PR China
    Vet Immunol Immunopathol 124:313-21. 2008
    ..This study provided basic information about blood cell count and T lymphocyte subsets in Chinese rhesus macaques. It may be useful for comparative studies using Indian and Chinese rhesus macaques...
  20. doi request reprint Hypotensive activity of novokinin, a potent analogue of ovokinin(2-7), is mediated by angiotensin AT(2) receptor and prostaglandin IP receptor
    Yuko Yamada
    Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji, Kyoto, Japan
    Peptides 29:412-8. 2008
    ..These suggest that the hypotensive activity is mediated by prostacyclin and the IP receptor downstream of the AT(2) receptor...
  21. ncbi request reprint Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II
    Justin M Cole
    Department of Pathology, Emory University, Atlanta, GA 30322, USA
    Hypertension 41:313-21. 2003
    ..The ACE 1/3 mice demonstrate the plasticity of the RAS and show that significant compensation is required to maintain normal, basal blood pressure in a mouse with an impaired local vascular and renal RAS...
  22. doi request reprint Disease progression patterns of SHIV-KB9 in rhesus macaques of Chinese origin in comparison with Indian macaques
    Qiang Liu
    State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
    Biomed Environ Sci 21:302-7. 2008
    ..To develop a model of SHIV-KB9/Chinese origin rhesus (Ch Rh) macaques for vaccine research and to compare the pathogenesis of SHIV-KB9 in Ch Rh macaques with that reported in Indian rhesus (Ind Rh) macaques...
  23. doi request reprint Anti-hypertensive activity of genetically modified soybean seeds accumulating novokinin
    Yuko Yamada
    Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji, Kyoto, Japan
    Peptides 29:331-7. 2008
    ..Defatted flour from the transgenic soybean also reduced the systolic blood pressure at a dose of 0.25 g/kg. Thus, the 4novokinin-alpha' produced in soybean exhibited an anti-hypertensive activity in SHRs after oral administration...
  24. pmc Functional variants of the NEIL1 and NEIL2 genes and risk and progression of squamous cell carcinoma of the oral cavity and oropharynx
    Xiadong Zhai
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 14:4345-52. 2008
    ..To date, only one reported study has investigated the association between NEIL1 and NEIL2 polymorphisms and cancer risk...
  25. pmc Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways
    Hui Zhao
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Development 135:1283-93. 2008
    ..We suggest that Lrig3 functions in NC formation in Xenopus by modulating the Wnt and Fgf signaling pathways...
  26. doi request reprint Atorvastatin slows the progression of cardiac remodeling in mice with pressure overload and inhibits epidermal growth factor receptor activation
    Yulin Liao
    Cardiovascular Division of Medicine, National Cardiovascular Center, Suita, Japan
    Hypertens Res 31:335-44. 2008
    ..These findings indicated that atorvastatin ameliorates cardiac remodeling in mice with pressure overload, and its actions are associated with inhibition of the EGFR signaling pathway...
  27. doi request reprint Severe eczema vaccinatum in a household contact of a smallpox vaccinee
    Surabhi Vora
    Section of Infectious Diseases, University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Clin Infect Dis 46:1555-61. 2008
    ..The father had a history of inactive eczema but reportedly reacted normally to the vaccine. The child's mother also developed contact vaccinia infection...
  28. doi request reprint Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura
    Jie Tao
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin 300020, People s Republic of China
    J Clin Immunol 28:432-9. 2008
    ..The aim of this study is to explore if DNA methylation plays a role in the pathogenesis of idiopathic thrombocytopenic purpura (ITP)...
  29. doi request reprint Met-Arg-Trp derived from Rubisco lowers blood pressure via prostaglandin D(2)-dependent vasorelaxation in spontaneously hypertensive rats
    Hui Zhao
    Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho Uji, Kyoto, Japan
    Peptides 29:345-9. 2008
    ..These findings suggest that the hypotensive activity of MRW is mainly caused by vasorelaxation rather than by ACE-inhibition...
  30. pmc Delineation of the Salmonella enterica serovar Typhimurium HilA regulon through genome-wide location and transcript analysis
    Inge M V Thijs
    Centre of Microbial and Plant Genetics, K U Leuven, Kasteelpark Arenberg 20, 3001 Leuven, Belgium
    J Bacteriol 189:4587-96. 2007
    ..Finally, the interactions of HilA with the SPI-2 secretion system gene ssaH and the flagellar gene flhD imply a repressor function for HilA under invasion-inducing conditions...
  31. ncbi request reprint [Immediate immunological effect of China-made recombinant hepatitis B vaccine expressed by transgenic Chinese hamster ovary cell line]
    Hongbin Liu
    Hebei Provincial Sanitation and Anti epidemic Station, Baoding, 071000, China
    Zhonghua Yi Xue Za Zhi 82:43-6. 2002
    ..To understand the protective efficacy of China-made recombinant hepatitis B vaccine expressed by transgenic Chinese hamster ovary cell line among newborns...
  32. ncbi request reprint Green fluorescent protein urea sensors. Uropathogenic Proteus mirabilis
    Christopher Coker
    Department of Microbiology and Immunology, University of Maryland, Baltimore, MD, USA
    Methods Mol Biol 183:287-93. 2002
  33. ncbi request reprint Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases
    Hui Zhao
    Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    FASEB J 17:723-4. 2003
    ..These data suggest that alterations in GCS expression following brief periods of oxidative stress in human endothelial cells lead to increased caspase activity...
  34. ncbi request reprint New approaches to genetic manipulation of mice: tissue-specific expression of ACE
    Justin M Cole
    Department of Pathology, Emory University, Atlanta, Georgia 30322, USA
    Am J Physiol Renal Physiol 284:F599-607. 2003
    ..Not only will these new genetic models be useful for studying blood pressure regulation but also they show great promise for the investigation of the function of the RAS in complicated disease models...
  35. ncbi request reprint Xenopus X-box binding protein 1, a leucine zipper transcription factor, is involved in the BMP signaling pathway
    Hui Zhao
    Department of Zoophysiology, University of Essen, Universitatsstrasse 5, D 45117 Essen, Germany
    Dev Biol 257:278-91. 2003
    ..Taken together, the results suggest a role for XXBP-1 in the control of neural differentiation, possibly as an activator...
  36. ncbi request reprint Basal nitric oxide production contributes to membrane potential and vasotone regulation of guinea pig in vitro spiral modiolar artery
    Zhi Gen Jiang
    Oregon Hearing Research Center, NRC 04, Oregon Health and Sciences University, Portland, OR 97201, USA
    Hear Res 189:92-100. 2004
    ..The basal release of NO also contributes to vasotone relaxation, but the K(ATP) activation appears to play little role in the relaxation of the in vitro SMA...
  37. ncbi request reprint Newly recognized physiologic and pathophysiologic actions of the angiotensin-converting enzyme
    Sebastien Fuchs
    Department of Pathology, Emory University, 101 Woodruff Circle, Atlanta, GA 30322, USA
    Curr Hypertens Rep 6:124-8. 2004
    ....
  38. ncbi request reprint Serum leptin levels in patients with idiopathic thrombocytopenic purpura
    Mei Zhan
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin 30020, China
    Eur J Haematol 72:348-52. 2004
    ..The purpose of this study was to evaluate serum leptin levels in idiopathic thrombocytopenic purpura (ITP), in order to determine the influence of leptin on the pathogenesis of ITP...
  39. ncbi request reprint The use of knockout mouse technology to achieve tissue selective expression of angiotensin converting enzyme
    Hong D Xiao
    Department of Pathology and Laboratory Medicine, Rm 7107A WMB, Emory University, Atlanta, GA 30322, USA
    J Mol Cell Cardiol 36:781-9. 2004
    ....
  40. ncbi request reprint XBP1 forms a regulatory loop with BMP-4 and suppresses mesodermal and neural differentiation in Xenopus embryos
    Ying Cao
    Abteilung Biochemie, Universitat Ulm, Albert Einstein Allee 11, D 89081 Ulm, Germany
    Mech Dev 123:84-96. 2006
    ..This dual activity depends upon binding of co-factors being involved in the formation of distinct transcription complexes...
  41. ncbi request reprint Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice
    Yulin Liao
    Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Cardiovasc Res 70:107-16. 2006
    ..This study was designed to determine whether impaired glucose tolerance develops during the progression of cardiac hypertrophy and heart failure, and whether tight glycemic control could reduce the severity of heart failure...
  42. ncbi request reprint [Inhibitory effect of antisense oligodeoxynucleotides targeting HER-2 mRNA on growth of breast cancer: experiment in vivo with mice]
    Jun Zhong Sun
    No 304 Clinical Department, General Hospital of Chinese People s Liberation Army, Beijing 100039, China
    Zhonghua Yi Xue Za Zhi 86:540-3. 2006
    ..To investigate the inhibitory effect of antisense oligodeoxynucleotides targeting HER-2 mRNA on growth of breast cancer...
  43. ncbi request reprint A transgenic rice seed accumulating an anti-hypertensive peptide reduces the blood pressure of spontaneously hypertensive rats
    Lijun Yang
    Transgenic Crop Research and Development Center, National Institute of Agrobiological Sciences NIAS, Tsukuba, Ibaraki 305 8602, Japan
    FEBS Lett 580:3315-20. 2006
    ..These results suggest the possible application of transgenic rice seed as a nutraceutical delivery system and specifically for administration of active peptides in hypertension...
  44. ncbi request reprint Leptin enhances in vitro secretion of IgG antiplatelet antibodies by splenocytes and peripheral blood mononuclear cells from patients with chronic idiopathic thrombocytopenic purpura
    He Ren
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, PR China
    Clin Immunol 120:205-11. 2006
    ..Further studies showed that leptin could increase platelet reactive T cells. These findings suggest that leptin may be involved in the pathogenesis of chronic ITP and might offer a potential target for the treatment of this disease...
  45. ncbi request reprint SBD.4 stimulates regenerative processes in vitro, and wound healing in genetically diabetic mice and in human skin/severe-combined immunodeficiency mouse chimera
    Hui Zhao
    Sunny BioDiscovery, Santa Clara, California 95050, USA
    Wound Repair Regen 14:593-601. 2006
    ..4a...
  46. ncbi request reprint Simultaneity of foetal heart rate acceleration and foetal trunk movement determined by foetal magnetocardiogram actocardiography
    Hui Zhao
    Department of Medical Physics, Medical Sciences Center, University of Wisconsin Madison, 53706, USA
    Phys Med Biol 47:839-46. 2002
    ..We also found that beat-to-beat FHR variability often decreased at or near the start of FHR accelerations and that this occurrence was an accurate marker of foetal movement onset, even when foetal movement onset lagged FHR accelerations...