Jarred W Younger
Affiliation: Stanford University
- Reduced cold pain tolerance in chronic pain patients following opioid detoxificationJarred Younger
Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, Palo Alto, California 94304 1573, USA
Pain Med 9:1158-63. 2008..Little scientific attention has been given to how cessation of opioid medication affects the hyperalgesic state. In this study, we examined the effects of opioid tapering on pain sensitivity in chronic pain patients...
- Chronic myofascial temporomandibular pain is associated with neural abnormalities in the trigeminal and limbic systemsJarred W Younger
Stanford University School of Medicine, Department of Anesthesia, Division of Pain Management, 780 Welch Rd, Suite 208E, Palo Alto, CA 94304, USA
Pain 149:222-8. 2010..The pattern of gray matter abnormality found in M-TMD individuals suggests the involvement of trigeminal and limbic system dysregulation, as well as potential somatotopic reorganization in the putamen, thalamus, and somatosensory cortex...
- Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levelsJarred Younger
Stanford University School of Medicine, Palo Alto, California 94304 1573, USA
Arthritis Rheum 65:529-38. 2013..Secondary outcomes included general satisfaction with life, positive mood, sleep quality, and fatigue...
- Development of the Stanford Expectations of Treatment Scale (SETS): a tool for measuring patient outcome expectancy in clinical trialsJarred Younger
Department of Anesthesia, Stanford University School of Medicine, CA 94304, USA
Clin Trials 9:767-76. 2012..There is therefore a need for a tool that prospectively predicts expectancy effects on treatment outcomes across a wide range of treatment modalities...
- Prescription opioid analgesics rapidly change the human brainJarred W Younger
Department of Anesthesia, School of Medicine, Stanford University, Palo Alto, CA 94304 1573, USA
Pain 152:1803-10. 2011..Morphologic changes occur rapidly in humans during new exposure to prescription opioid analgesics. Further research is needed to determine the clinical impact of those opioid-induced gray matter changes...
- Pain outcomes: a brief review of instruments and techniquesJarred Younger
Department of Anesthesia, Division of Pain Management, Stanford University School of Medicine, 780 Welch Road, Suite 208C, Palo Alto, CA 94304 1573, USA
Curr Pain Headache Rep 13:39-43. 2009..By selecting the proper tools and employing them correctly, we can obtain highly reliable and valid measures of pain outcomes in research and clinical care...
- Effects of naltrexone on pain sensitivity and mood in fibromyalgia: no evidence for endogenous opioid pathophysiologyJarred W Younger
Department of Anesthesia, Stanford University School of Medicine, Palo Alto, California, United States of America
PLoS ONE 4:e5180. 2009..Consistent with prior research, there was no evidence found for abnormal endogenous opioid activity in women with fibromyalgia...
- Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot studyJarred Younger
School of Medicine, Department of Anesthesia, Division of Pain Management, Stanford University, 780 Welch Road, Suite 208, Palo Alto, CA 94304 1573, USA
Pain Med 10:663-72. 2009..In this pilot clinical trial, we tested the effectiveness of low-dose naltrexone in treating the symptoms of fibromyalgia...
- Pain Duration and Resolution following Surgery: An Inception Cohort StudyIan R Carroll
Departments of Anesthesiology, Perioperative, and Pain Medicine, Division of Pain Medicine, Stanford University, Palo Alto, California, USA
Pain Med 16:2386-96. 2015..Preoperative determinants of pain duration following surgery are poorly understood. We identified preoperative predictors of prolonged pain after surgery in a mixed surgical cohort...
- A pilot cohort study of the determinants of longitudinal opioid use after surgeryIan Carroll
Department of Anesthesia, Division of Pain Management, Stanford University, Palo Alto, CA 94035, USA
Anesth Analg 115:694-702. 2012..Determinants of the duration of opioid use after surgery have not been reported. We hypothesized that both preoperative psychological distress and substance abuse would predict more prolonged opioid use after surgery...
- Self-loathing aspects of depression reduce postoperative opioid cessation rateJennifer M Hah
Division of Pain Medicine, Stanford University, Palo Alto, California, USA
Pain Med 15:954-64. 2014..We aimed to identify the underlying factors of the BDI-II (affective/cognitive vs somatic) associated with a decreased rate of opioid cessation after surgery...
- Effects of naltrexone on repressive coping and disclosure of emotional material: a test of the opioid-peptide hypothesis of repression and hypertensionJarred W Younger
Stanford University School of Medicine, Department of Anesthesia, Pain Research, MC 5747, 780 Welch Rd, Suite 208, Palo Alto, CA 94304, USA
Psychosom Med 68:734-41. 2006..The present study was designed to assess the role of endogenous opioids in the relationship of hypertension to repressive coping...
- Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathologyElizabeth Ann Stringer
Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94304, USA
J Transl Med 11:93. 2013..Single time-point approaches potentially overlook important features of CFS, such as fluctuations in fatigue severity. We have observed that individuals with CFS demonstrate significant day-to-day variability in their fatigue severity...
- Acute opioid withdrawal is associated with increased neural activity in reward-processing centers in healthy men: A functional magnetic resonance imaging studyLarry F Chu
Department of Anesthesia, Stanford University School of Medicine, 300 Pasteur Drive, Grant Building Room S268C, Stanford, CA 94305, United States Electronic address
Drug Alcohol Depend 153:314-22. 2015..The purpose of this current study was to characterize neural activity associated with acute opioid withdrawal and examine whether these changes are modified by ondansetron...
- Hypnotizability and somatic complaints: a gender-specific phenomenonJarred W Younger
Stanford University School of Medicine, Department of Anesthesea, Stanford, California 94304 1573, USA
Int J Clin Exp Hypn 55:1-13. 2007..The results call into question some claims that high hypnotizability is an adaptive and healthy trait...