Yanmin Yang

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Giant axonal neuropathy
    Y Yang
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305 5489, USA
    Cell Mol Life Sci 64:601-9. 2007
  2. pmc Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin
    Jianqing Ding
    Department of Neurology, Stanford University School of Medicine, CA 94305, USA
    J Cell Biol 158:427-33. 2002
  3. pmc Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats
    Wei Wang
    Department of Neurology, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e33094. 2012
  4. pmc BPAG1n4 is essential for retrograde axonal transport in sensory neurons
    Jia Jia Liu
    Department of Neurology, Stanford University School of Medicine, Stanford, CA 94305 5489, USA
    J Cell Biol 163:223-9. 2003
  5. ncbi request reprint Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport
    Jianqing Ding
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 1201 Welch Road, CA 94305 5489, USA
    Hum Mol Genet 15:1451-63. 2006
  6. pmc Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport
    Jia Jia Liu
    Department of Neurology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:2223-8. 2007
  7. ncbi request reprint A functional dynein-microtubule network is required for NGF signaling through the Rap1/MAPK pathway
    Chengbiao Wu
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Traffic 8:1503-20. 2007
  8. ncbi request reprint Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway
    Wei Wang
    Department of Neurology and Neurological Sciences, Stanford University, 1201 Welch Road, MSLS P207, Stanford, California 94305, USA
    Curr Biol 15:2050-5. 2005
  9. ncbi request reprint Microtubule-associated protein 8 contains two microtubule binding sites
    Jianqing Ding
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 1201 Welch Road, Stanford, CA 94305 5489, USA
    Biochem Biophys Res Commun 339:172-9. 2006
  10. pmc Calcium tips the balance: a microtubule plus end to lattice binding switch operates in the carboxyl terminus of BPAG1n4
    Mridu Kapur
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, MSLS Building, Room P259, 1201 Welch Road, Stanford, California 94305, USA
    EMBO Rep 13:1021-9. 2012

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Giant axonal neuropathy
    Y Yang
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305 5489, USA
    Cell Mol Life Sci 64:601-9. 2007
    ..However, many key questions about the disease remain unanswered...
  2. pmc Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin
    Jianqing Ding
    Department of Neurology, Stanford University School of Medicine, CA 94305, USA
    J Cell Biol 158:427-33. 2002
    ..Our findings may provide important insights into the pathogenesis of neurodegenerative disorders related to cytoskeletal abnormalities...
  3. pmc Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats
    Wei Wang
    Department of Neurology, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e33094. 2012
    ..Together, these results imply that nemitin may play an important role in regulating the neuronal cytoskeleton through an interaction with MAP8...
  4. pmc BPAG1n4 is essential for retrograde axonal transport in sensory neurons
    Jia Jia Liu
    Department of Neurology, Stanford University School of Medicine, Stanford, CA 94305 5489, USA
    J Cell Biol 163:223-9. 2003
    ..We conclude that BPAG1n4 plays an essential role in retrograde axonal transport in sensory neurons. These findings might advance our understanding of pathogenesis of axonal degeneration and neuronal death...
  5. ncbi request reprint Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport
    Jianqing Ding
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 1201 Welch Road, CA 94305 5489, USA
    Hum Mol Genet 15:1451-63. 2006
    ..We propose that the axonal transport impairment may be a deleterious consequence of accumulated, toxic MAP8 protein...
  6. pmc Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport
    Jia Jia Liu
    Department of Neurology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:2223-8. 2007
    ..Our work lays the foundation for understanding fundamental issues of axonal transport and provides insights into the molecular mechanisms underlying human neurodegenerative disorders...
  7. ncbi request reprint A functional dynein-microtubule network is required for NGF signaling through the Rap1/MAPK pathway
    Chengbiao Wu
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    Traffic 8:1503-20. 2007
    ..Dynein- and microtubule-based transport is thus necessary for TrkA signaling to Rap1 and MAPK1/2...
  8. ncbi request reprint Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway
    Wei Wang
    Department of Neurology and Neurological Sciences, Stanford University, 1201 Welch Road, MSLS P207, Stanford, California 94305, USA
    Curr Biol 15:2050-5. 2005
    ..Our study provides important insight into pathogenesis of neurodegenerative diseases associated with cytoskeletal abnormalities...
  9. ncbi request reprint Microtubule-associated protein 8 contains two microtubule binding sites
    Jianqing Ding
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 1201 Welch Road, Stanford, CA 94305 5489, USA
    Biochem Biophys Res Commun 339:172-9. 2006
    ..The association of the carboxyl terminal of the light chain with actin microfilaments could also be detected. Our findings define MAP8 as a novel microtubule associated protein containing two microtubule binding domains...
  10. pmc Calcium tips the balance: a microtubule plus end to lattice binding switch operates in the carboxyl terminus of BPAG1n4
    Mridu Kapur
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, MSLS Building, Room P259, 1201 Welch Road, Stanford, California 94305, USA
    EMBO Rep 13:1021-9. 2012
    ..This switch is EF-hand dependent, and mutations of the EF-hands abolish this dynamic behaviour. Our study thus uncovers a new, calcium-dependent regulatory mechanism for a spectraplakin, BPAG1n4, at the MT plus end...
  11. ncbi request reprint Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival
    Elizabeth Allen
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 1201 Welch Road, Stanford, California 94305 5489, USA
    Nature 438:224-8. 2005
    ..Our results identify gigaxonin as a ubiquitin scaffolding protein that controls MAP1B-LC degradation, and provide insight into the molecular mechanisms underlying human neurodegenerative disorders...
  12. ncbi request reprint Better protection of pulmonary surfactant integrity with deep hypothermia and circulatory arrest
    Yanmin Yang
    Department of Cardiovascular and Thoracic Surgery, XinHua Hospital Shanghai Children s Medical Center, Shanghai Second Medical University, Shanghai, People s Republic of China
    Ann Thorac Surg 82:131-6; discussion 136-7. 2006
    ..This study was conducted to determine the influence of either strategy on surfactant metabolism and pulmonary function with neonatal piglet model...

Research Grants9

  1. Characterizing BPAG1n4, a Sensory Neuron's Sustainer
    Yanmin Yang; Fiscal Year: 2002
    ..Our findings wilt lead to a better understanding and possible treatment for neurodegenerative disorders. ..
  2. Characterizing BPAG1n4, a Sensory Neuron's Sustainer
    Yanmin Yang; Fiscal Year: 2003
    ..Our findings wilt lead to a better understanding and possible treatment for neurodegenerative disorders. ..
  3. Characterizing BPAG1n4, a Sensory Neuron's Sustainer
    Yanmin Yang; Fiscal Year: 2004
    ..Our findings wilt lead to a better understanding and possible treatment for neurodegenerative disorders. ..
  4. Characterizing BPAG1n4, a Sensory Neuron's Sustainer
    Yanmin Yang; Fiscal Year: 2005
    ..Our findings wilt lead to a better understanding and possible treatment for neurodegenerative disorders. ..
  5. Functions of BPAG1n
    Yanmin Yang; Fiscal Year: 2006
    ..The Department of Neurology at Stanford University provides an ideal environment for developing my academic career into a leading investigator in the neurobiology of disease. ..
  6. Characterizing BPAG1n4, a Sensory Neuron's Sustainer
    Yanmin Yang; Fiscal Year: 2006
    ..Our findings wilt lead to a better understanding and possible treatment for neurodegenerative disorders. ..
  7. Characterizing mechanisms underlying neurodegeneration in GAN
    Yanmin Yang; Fiscal Year: 2009
    ..Thorough understanding of the pathological pathway in GAN may provide strong insight into other degenerative diseases. The finding may lead to therapies to target more common symptoms of neurodegeneration. ..
  8. Characterizing mechanisms underlying neurodegeneration in GAN
    Yanmin Yang; Fiscal Year: 2010
    ..Thorough understanding of the pathological pathway in GAN may provide strong insight into other degenerative diseases. The finding may lead to therapies to target more common symptoms of neurodegeneration. ..