Douglas E Wright

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Nerve growth factor blocks the glucose-induced down-regulation of caveolin-1 expression in Schwann cells via p75 neurotrophin receptor signaling
    Wenbin Tan
    Department of Pharmacology and Toxicology, University of Kansas, Lawrence, Kansas 66045, USA
    J Biol Chem 278:23151-62. 2003
  2. pmc Hematopoietic stem cells are uniquely selective in their migratory response to chemokines
    Douglas E Wright
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Exp Med 195:1145-54. 2002
  3. pmc Circulation and chemotaxis of fetal hematopoietic stem cells
    Julie L Christensen
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    PLoS Biol 2:E75. 2004
  4. pmc Pro-NGF, sortilin, and p75NTR: potential mediators of injury-induced apoptosis in the mouse dorsal root ganglion
    Melinda G Arnett
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
    Brain Res 1183:32-42. 2007
  5. pmc Diabetes-induced chemogenic hypoalgesia is paralleled by attenuated stimulus-induced fos expression in the spinal cord of diabetic mice
    Megan S Johnson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Pain 8:637-49. 2007
  6. pmc Prenatal exposure to elevated NT3 disrupts synaptic selectivity in the spinal cord
    Zhi Wang
    Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Neurosci 27:3686-94. 2007
  7. ncbi request reprint Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury
    Michael D Taylor
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Exp Neurol 191:211-22. 2005
  8. pmc Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate
    Aziz Moqrich
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
    Nat Neurosci 7:812-8. 2004
  9. ncbi request reprint Beneficial actions of neurotrophin treatment on diabetes-induced hypoalgesia in mice
    Julie A Christianson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Pain 4:493-504. 2003
  10. ncbi request reprint Restorative effects of neurotrophin treatment on diabetes-induced cutaneous axon loss in mice
    Julie A Christianson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City 66160, USA
    Exp Neurol 179:188-99. 2003

Collaborators

  • Amy J Wagers
  • Eugene C Butcher
  • IRVING LERNER WEISSMAN
  • Julie L Christensen
  • Janelle M Ryals
  • Julie A Christianson
  • Michael D Taylor
  • Karra A Muller
  • Megan S Johnson
  • Zhi Wang
  • Melinda G Arnett
  • Aziz Moqrich
  • Wenbin Tan
  • Eva L Feldman
  • Eric Frank
  • Ling Ying Li
  • Angela S Holdeman
  • Simeon G Weltmer
  • James Watson
  • Dionisio Martin-Zanca
  • Ardem Patapoutian
  • Taryn J Earley
  • Carey Backus
  • Mary Andahazy
  • Louis F Reichardt
  • Kristin M Barkus
  • Yelena S Dremina
  • Shefali Rouen
  • Kenneth E McCarson
  • Rick T Dobrowsky
  • John T Riekhof
  • Sung Ok Yoon
  • Dongwei Hui

Detail Information

Publications11

  1. ncbi request reprint Nerve growth factor blocks the glucose-induced down-regulation of caveolin-1 expression in Schwann cells via p75 neurotrophin receptor signaling
    Wenbin Tan
    Department of Pharmacology and Toxicology, University of Kansas, Lawrence, Kansas 66045, USA
    J Biol Chem 278:23151-62. 2003
    ....
  2. pmc Hematopoietic stem cells are uniquely selective in their migratory response to chemokines
    Douglas E Wright
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Exp Med 195:1145-54. 2002
    ..The sharply restricted chemotactic responsiveness of HSC is unique among leukocytes and may be necessary for the specific homing of circulating HSC to bone marrow, as well as for the maintenance of HSC in hematopoietic microenvironments...
  3. pmc Circulation and chemotaxis of fetal hematopoietic stem cells
    Julie L Christensen
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    PLoS Biol 2:E75. 2004
    ..This finding indicates the importance of the combined effects of SLF and SDF-1alpha in the migration of fetal HSCs, and is, to our knowledge, the first demonstration of a synergistic effect of two chemoattractive agents on HSCs...
  4. pmc Pro-NGF, sortilin, and p75NTR: potential mediators of injury-induced apoptosis in the mouse dorsal root ganglion
    Melinda G Arnett
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
    Brain Res 1183:32-42. 2007
    ..These results propose pro-NGF-induced, p75NTR-sortilin-mediated neuronal death as a critical aspect of nerve injury-induced death in the DRG...
  5. pmc Diabetes-induced chemogenic hypoalgesia is paralleled by attenuated stimulus-induced fos expression in the spinal cord of diabetic mice
    Megan S Johnson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Pain 8:637-49. 2007
    ..This murine model may be better suited to understanding the insensate symptoms of diabetic patients in the absence of chronic pain...
  6. pmc Prenatal exposure to elevated NT3 disrupts synaptic selectivity in the spinal cord
    Zhi Wang
    Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Neurosci 27:3686-94. 2007
    ..These results indicate that prenatal exposure to elevated levels of NT3 disrupts the normal mechanisms responsible for synaptic selectivity in the stretch reflex circuit...
  7. ncbi request reprint Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury
    Michael D Taylor
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Exp Neurol 191:211-22. 2005
    ..Finally, exposure of muscle afferent fibers to NT-3 prior to injury alters axonal responses both in vitro and in vivo...
  8. pmc Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate
    Aziz Moqrich
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
    Nat Neurosci 7:812-8. 2004
    ..The surviving presumptive TrkA-expressing neurons adopted a proprioceptive phenotype, indicating that neurotrophin signaling can specify sensory neuron subtypes...
  9. ncbi request reprint Beneficial actions of neurotrophin treatment on diabetes-induced hypoalgesia in mice
    Julie A Christianson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Pain 4:493-504. 2003
    ..Furthermore, these studies show that dorsal root ganglion neurons in diabetic mice are responsive to treatment with either NGF or GDNF; however, these 2 neurotrophins differ in their ability to affect distinct somatosensations...
  10. ncbi request reprint Restorative effects of neurotrophin treatment on diabetes-induced cutaneous axon loss in mice
    Julie A Christianson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City 66160, USA
    Exp Neurol 179:188-99. 2003
    ..Importantly, intrathecal treatment using GDNF or NTN strongly stimulated axon growth and branching, suggesting that administration of these trophic factors can improve cutaneous innervation deficits caused by diabetes...
  11. doi request reprint Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice
    Karra A Muller
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Diabetes 57:1693-701. 2008
    ..In addition, diabetic mice were treated with insulin to assess whether sensorimotor and spindle deficits were reversible...