R J Wong

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Metalloporphyrins - an update
    Stephanie Schulz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine Stanford, CA, USA
    Front Pharmacol 3:68. 2012
  2. ncbi request reprint Effects of light on metalloporphyrin-treated newborn mice
    Ronald J Wong
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Acta Paediatr 103:474-9. 2014
  3. pmc Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model
    Stephanie Schulz
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Physiol Gastrointest Liver Physiol 304:G991-G1001. 2013
  4. doi request reprint A deficiency in haem oxygenase-1 induces foetal growth restriction by placental vasculature defects
    Ronald J Wong
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Acta Paediatr 101:827-34. 2012
  5. doi request reprint In vitro inhibition of heme oxygenase isoenzymes by metalloporphyrins
    R J Wong
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    J Perinatol 31:S35-41. 2011
  6. ncbi request reprint Prediction of hyperbilirubinemia in near-term and term infants
    D K Stevenson
    Department of Pediatrics, Lucile Salter Packard Children's Hospital, Stanford, California, USA
    Pediatrics 108:31-9. 2001
  7. ncbi request reprint Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron-ascorbate system
    H J Vreman
    Department of Pediatrics, Neonatal and Developmental Medicine Laboratory, Stanford University School of Medicine, CA 94305 5208, USA
    Can J Physiol Pharmacol 76:1057-65. 1998
  8. pmc Carbon monoxide detection and biological investigations
    D K Stevenson
    Department of Pediatrics, Stanford University School of Medicine, CA 94305 5208, USA
    Trans Am Clin Climatol Assoc 111:61-75. 2000
  9. ncbi request reprint Validation of the Natus CO-Stat End Tidal Breath Analyzer in children and adults
    H J Vreman
    Departments of Pediatric, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Clin Monit Comput 15:421-7. 1999
  10. ncbi request reprint Carbon monoxide and bilirubin production in neonates
    D K Stevenson
    Department of Pediatrics, Stanford University School of Medicine, CA 94304 1510, USA
    Semin Perinatol 25:85-93. 2001

Detail Information

Publications17

  1. pmc Metalloporphyrins - an update
    Stephanie Schulz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine Stanford, CA, USA
    Front Pharmacol 3:68. 2012
    ..Ongoing research continues in the pursuit of identifying ideal metalloporphyrins, which are safe and effective, by defining therapeutic windows and targeted interventions for the treatment of excessive neonatal hyperbilirubinemia...
  2. ncbi request reprint Effects of light on metalloporphyrin-treated newborn mice
    Ronald J Wong
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Acta Paediatr 103:474-9. 2014
    ..Intragastric administration of ZnPP microparticles (30 ╬╝mol/kg) to 3-day-old mice resulted in a twofold increase in potency and no signs of phototoxicity...
  3. pmc Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model
    Stephanie Schulz
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Physiol Gastrointest Liver Physiol 304:G991-G1001. 2013
    ..We conclude that a partial HO-1 deficiency promotes experimental NEC-like intestinal injury, possibly mediated by exaggerated inflammation and disruption in tissue repair...
  4. doi request reprint A deficiency in haem oxygenase-1 induces foetal growth restriction by placental vasculature defects
    Ronald J Wong
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Acta Paediatr 101:827-34. 2012
    ....
  5. doi request reprint In vitro inhibition of heme oxygenase isoenzymes by metalloporphyrins
    R J Wong
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    J Perinatol 31:S35-41. 2011
    ..Although bilirubin production is due to the activity of both HO-1 and HO-2, the inhibition of HO-1 with a relative sparing of HO-2 activity might provide the most selective approach for the treatment of hemolytic disease...
  6. ncbi request reprint Prediction of hyperbilirubinemia in near-term and term infants
    D K Stevenson
    Department of Pediatrics, Lucile Salter Packard Children's Hospital, Stanford, California, USA
    Pediatrics 108:31-9. 2001
    ..Depending on the incidence of hyperbilirubinemia within an institution, the criteria for decision making should vary according to its unique population...
  7. ncbi request reprint Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron-ascorbate system
    H J Vreman
    Department of Pediatrics, Neonatal and Developmental Medicine Laboratory, Stanford University School of Medicine, CA 94305 5208, USA
    Can J Physiol Pharmacol 76:1057-65. 1998
    ..We conclude that CO generation is associated with the process of in vitro lipid peroxidation in tissues with limited antioxidant reserves...
  8. pmc Carbon monoxide detection and biological investigations
    D K Stevenson
    Department of Pediatrics, Stanford University School of Medicine, CA 94305 5208, USA
    Trans Am Clin Climatol Assoc 111:61-75. 2000
    ..It may be shown that the integrity of the heme catabolic pathway, which is ever present and plays a role in every tissue, is central to the existence of most complex organisms...
  9. ncbi request reprint Validation of the Natus CO-Stat End Tidal Breath Analyzer in children and adults
    H J Vreman
    Departments of Pediatric, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Clin Monit Comput 15:421-7. 1999
    ..that also reports end tidal carbon dioxide (ETCO2) and respiratory rate (RR), was compared to established, marketed (predicate) devices in children (n = 39) and adults (n = 48) who are normal or at-risk of elevated CO excretion...
  10. ncbi request reprint Carbon monoxide and bilirubin production in neonates
    D K Stevenson
    Department of Pediatrics, Stanford University School of Medicine, CA 94304 1510, USA
    Semin Perinatol 25:85-93. 2001
    ..This report provides a brief overview of these interrelationships in the hope that it may provide insight into the central role this pathway plays in the existence of most organisms...
  11. pmc Effect of heme oxygenase-1 deficiency on placental development
    H Zhao
    Dept of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Placenta 30:861-8. 2009
    ..We conclude that a partial deficiency in HO-1 is associated with morphological changes in the placenta and elevations in maternal diastolic blood pressure and plasma sFlt-1 levels, despite a compensatory increase in HO-2 expression...
  12. ncbi request reprint Haem oxygenase activity in human umbilical cord and rat vascular tissues
    H J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, 94305 5119, USA
    Placenta 21:337-44. 2000
    ..We conclude that the presence of HO activity in cord tissues supports the possibility that CO plays a role in fetoplacental blood flow regulation...
  13. ncbi request reprint Prediction of hyperbilirubinemia in near-term and term infants
    D K Stevenson
    Department of Pediatrics, Lucile Salter Packard Children's Hospital, Stanford, CA 94305-5208, USA
    J Perinatol 21:S63-72; discussion S83-7. 2001
    ..Depending on the incidence of hyperbilirubinemia within an institution, the criteria for decision making should vary according to its unique population...
  14. doi request reprint Combining hand techniques with electric pumping increases the caloric content of milk in mothers of preterm infants
    J Morton
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94025, USA
    J Perinatol 32:791-6. 2012
    ..In this study, we compared milk composition between mothers stratified by early hand expression frequency...
  15. doi request reprint Standardized bench method for evaluating the efficacy of phototherapy devices
    H J Vreman
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Acta Paediatr 97:308-16. 2008
    ..As phototherapy (PT) devices employ a variety of broadband light sources, we developed and tested a standardized bench method for evaluating the efficacy of some devices...
  16. doi request reprint Combining hand techniques with electric pumping increases milk production in mothers of preterm infants
    J Morton
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94025, USA
    J Perinatol 29:757-64. 2009
    ..We observed additional milk could be expressed following pumping using hand techniques. We explored the effect on production of hand expression of colostrum and hands-on pumping (HOP) of mature milk...
  17. ncbi request reprint The jaundiced newborn. Understanding and managing transitional hyperbilirubinemia
    D K Stevenson
    Division of Neonatal, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Minerva Pediatr 54:373-82. 2002
    ..In this review, we will discuss the various risk factors associated with hyperbilirubinemia and describe strategies for the diagnosis and management of transitional hyperbilirubinemia...