Research Topics
Species | Jonathan P WisorSummaryAffiliation: Stanford University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Dopaminergic role in stimulant-induced wakefulnessJ P Wisor
Sleep Disorders Research Center, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
J Neurosci 21:1787-94. 2001..Thus, dopamine transporters play an important role in sleep regulation and are necessary for the specific wake-promoting action of amphetamines and modafinil...
Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptorJonathan P Wisor
Stanford University Sleep Research Center, 701 Welch Road, Suite 2226 Palo Alto, CA 94304, USA
Brain Res 955:221-8. 2002..The former but not the latter response to midazolam was intact in the knockout. These results further support a role for GABAergic transmission in regulating REM sleep and EEG spectral phenomena associated with NREM sleep...
A role for cryptochromes in sleep regulationJonathan P Wisor
Dept of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
BMC Neurosci 3:20. 2002..We studied sleep in cry1,2-/- mice under baseline conditions as well as under conditions of constant darkness and enforced wakefulness to determine whether cryptochromes influence sleep regulatory processes...
Altered rapid eye movement sleep timing in serotonin transporter knockout miceJ P Wisor
Sleep and Circadian Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94304, USA
Neuroreport 14:233-8. 2003..Genetic differences in serotonin systems and developmental exposure to SERT blockers are likely to exert effects on REMS...
Disorders of the circadian clock: etiology and possible therapeutic targetsJ P Wisor
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
Curr Drug Targets CNS Neurol Disord 1:555-66. 2002..The proteins encoded by these genetic loci play key roles in the intracellular feedback loop that generates circadian rhythms, and thus represent therapeutic targets for the treatment of both endogenous and exogenous circadian disorders...
Armodafinil, the R-enantiomer of modafinil: wake-promoting effects and pharmacokinetic profile in the ratJonathan P Wisor
Stanford Sleep Disorders Clinic and Research Laboratory, 701 Welch Rd, Suite 2226, Stanford, CA 94304, USA
Pharmacol Biochem Behav 85:492-9. 2006....
Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 releaseShengwen Zhang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA
Sleep 27:619-27. 2004..No correlation was found between CSF hypocretin-1 and corticosterone. CONCLUSIONS: Hypocretin-1 release is under SCN control. Locomotor activity influences the activity of the hypocretin neurons...
Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strainsJonathan P Wisor
Biosciences Division, SRI International, Menlo Park, California 94025, USA
J Neurosci 28:7193-201. 2008....
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesiaXinmin Xie
Biosciences Division, SRI International, Menlo Park, California 94025, USA
J Clin Invest 118:2471-81. 2008..These results establish what is, to our knowledge, a novel interaction between the N/OFQ and Hcrt systems in which the corticotropin-releasing factor and N/OFQ systems coordinately modulate the Hcrt neurons to regulate SIA...
A novel quantitative trait locus on mouse chromosome 18, "era1," modifies the entrainment of circadian rhythmsJonathan P Wisor
Molecular Neurobiology Laboratory, SRI International, Menlo Park, CA 94025, USA
Sleep 30:1255-63. 2007..We now describe a novel circadian rhythm phenotype, and a locus influencing that phenotype, in a segregating population of mice...
Molecular genetic advances in sleep research and their relevance to sleep medicineJonathan P Wisor
Molecular Neurobiology Laboratory, Biosciences Division, SRI International, Menlo Park, CA 94025, USA
Sleep 28:357-67. 2005....
Identification of a population of sleep-active cerebral cortex neuronsDmitry Gerashchenko
Biosciences Division, SRI International, Menlo Park, CA 94025, USA
Proc Natl Acad Sci U S A 105:10227-32. 2008....
Gene expression in the rat brain during prostaglandin D2 and adenosinergically-induced sleepAkira Terao
Biosciences Division, SRI International, Menlo Park, California 94025, USA
J Neurochem 105:1480-98. 2008..However, gene expression induced in the brain after PGD2 or CGS21680 treatment was distinct from that described during RS after SD and apparently involves glial cell gene activation and signaling pathways in neural-immune interactions...
