Wolfgang C Winkelmayer

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Propensity scores in the presence of effect modification: A case study using the comparison of mortality on hemodialysis versus peritoneal dialysis
    Ylian S Liem
    Program for the Assessment of Radiological Technology ART Program, Department of Epidemiology and Biostatistics and the Department of Radiology, Erasmus University Medical Center Rotterdam, Dr, Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Emerg Themes Epidemiol 7:1. 2010
  2. doi Predialyis nephrology care of older individuals approaching end-stage renal disease
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Semin Dial 25:628-32. 2012
  3. pmc Prevalence of atrial fibrillation and warfarin use in older patients receiving hemodialysis
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Nephrol 25:341-53. 2012
  4. ncbi Comparative effectiveness research: what is it and why do we need it in nephrology?
    Tara I Chang
    Nephrol Dial Transplant 27:2156-61. 2012
  5. doi Altitude and the risk of cardiovascular events in incident US dialysis patients
    Wolfgang C Winkelmayer
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
    Nephrol Dial Transplant 27:2411-7. 2012
  6. pmc Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillation
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 6:2662-8. 2011
  7. doi Potential effects of the new Medicare Prospective Payment System on drug prescription in end-stage renal disease care
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Palo Alto, CA 94304, USA
    Blood Purif 31:66-9. 2011
  8. pmc The increasing prevalence of atrial fibrillation among hemodialysis patients
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Suite 106, Palo Alto, CA 94304, USA
    J Am Soc Nephrol 22:349-57. 2011
  9. pmc Comparative effectiveness of calcium-containing phosphate binders in incident U.S. dialysis patients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 6:175-83. 2011
  10. ncbi Predialysis nephrology care of older patients approaching end-stage renal disease
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Arch Intern Med 171:1371-8. 2011

Detail Information

Publications88

  1. pmc Propensity scores in the presence of effect modification: A case study using the comparison of mortality on hemodialysis versus peritoneal dialysis
    Ylian S Liem
    Program for the Assessment of Radiological Technology ART Program, Department of Epidemiology and Biostatistics and the Department of Radiology, Erasmus University Medical Center Rotterdam, Dr, Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Emerg Themes Epidemiol 7:1. 2010
    ..Our aim was to compare a propensity score-stratified model with a traditional multivariable-adjusted model, specifically in estimating survival of hemodialysis (HD) versus peritoneal dialysis (PD) patients...
  2. doi Predialyis nephrology care of older individuals approaching end-stage renal disease
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Semin Dial 25:628-32. 2012
    ..Defining the appropriate role and involvement of nephrologists in the decision about initiating renal replacement therapy in older adults seems ripe for further investigation and discussion...
  3. pmc Prevalence of atrial fibrillation and warfarin use in older patients receiving hemodialysis
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Nephrol 25:341-53. 2012
    ..Little is known about the use of warfarin in hemodialysis (HD) patients with atrial fibrillation (AF). We studied temporal trends of AF among older HD patients, and of warfarin use among those with AF...
  4. ncbi Comparative effectiveness research: what is it and why do we need it in nephrology?
    Tara I Chang
    Nephrol Dial Transplant 27:2156-61. 2012
    ..Finally, we will discuss why CER pertaining to kidney disease care needs to be a top priority in order to move our field from a largely opinion-based specialty to an evidence-based specialty...
  5. doi Altitude and the risk of cardiovascular events in incident US dialysis patients
    Wolfgang C Winkelmayer
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
    Nephrol Dial Transplant 27:2411-7. 2012
    ..We hypothesized that higher altitude would be associated with lower rates of cardiovascular events due to an altered physiological response of dialysis patients to altitude induced hypoxia...
  6. pmc Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillation
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 6:2662-8. 2011
    ..Although generally recommended in atrial fibrillation (AF) patients, the effectiveness and safety of oral anticoagulation in dialysis patients with AF is unknown...
  7. doi Potential effects of the new Medicare Prospective Payment System on drug prescription in end-stage renal disease care
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Palo Alto, CA 94304, USA
    Blood Purif 31:66-9. 2011
    ..On aggregate, these changes have the potential to alter patient outcomes, but it is currently unclear how these will be and can be monitored...
  8. pmc The increasing prevalence of atrial fibrillation among hemodialysis patients
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Suite 106, Palo Alto, CA 94304, USA
    J Am Soc Nephrol 22:349-57. 2011
    ..Identifying potentially modifiable risk factors for incident atrial fibrillation requires further investigation...
  9. pmc Comparative effectiveness of calcium-containing phosphate binders in incident U.S. dialysis patients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 6:175-83. 2011
    ..We studied the association between use versus nonuse of calcium-containing phosphate binders (CCPBs) and mortality from any cause. We also tested whether mortality differed among users of individual CCPBs...
  10. ncbi Predialysis nephrology care of older patients approaching end-stage renal disease
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Arch Intern Med 171:1371-8. 2011
    ..Little is known about trends in the timing of first nephrology consultation and associated outcomes among older patients initiating dialysis...
  11. doi Guideline-conformity of initiation with oral hypoglycemic treatment for patients with newly therapy-dependent type 2 diabetes mellitus in Austria
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Pharmacoepidemiol Drug Saf 20:57-65. 2011
    ..To determine guideline conformity of initiation of oral hypoglycemic (OH) treatment for type 2 diabetes in Austria; to study patient and prescriber correlates of recommended initiation with metformin monotherapy...
  12. ncbi Confusion about the appropriate use of erythropoiesis-stimulating agents in patients undergoing maintenance dialysis
    Wolfgang C Winkelmayer
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Semin Dial 23:486-91. 2010
    ....
  13. pmc Variation in initial kidney replacement therapy for end-stage renal disease due to lupus nephritis in the United States
    Amy Devlin
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 63:1642-53. 2011
    ..We aimed to identify sociodemographic and clinical factors associated with variation in initial kidney replacement therapies among LN ESRD patients...
  14. pmc Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004
    Candace H Feldman
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 65:753-63. 2013
    ..This study was undertaken to investigate the epidemiology and sociodemographics of SLE and LN in the low-income US Medicaid population...
  15. pmc Associations of kidney function with cardiovascular medication use after myocardial infarction
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Clin J Am Soc Nephrol 3:1415-22. 2008
    ..It is unknown whether adherence to recommended medications after myocardial infarction (MI) differs by kidney function...
  16. doi Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysis
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
    J Am Coll Cardiol 51:1247-54. 2008
    ..We sought to assess the relationship between increasing use of cardiovascular medications and trends in long-term prognosis after myocardial infarction (MI) in the elderly...
  17. doi Validation of reported predialysis nephrology care of older patients initiating dialysis
    Jane Paik Kim
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Palo Alto, CA 94304, USA
    J Am Soc Nephrol 23:1078-85. 2012
    ..More-specific instructions may improve reporting and increase the utility of form CMS-2728 for research and public health surveillance...
  18. ncbi A propensity analysis of late versus early nephrologist referral and mortality on dialysis
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Nephrol 14:486-92. 2003
    ..Further research is needed to identify patients at particular risk so that interventions to prevent early deaths on dialysis in LR patients can be developed and tested...
  19. ncbi Underuse of ACE inhibitors and angiotensin II receptor blockers in elderly patients with diabetes
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Kidney Dis 46:1080-7. 2005
    ..However, little is known about the adequacy of adherence to these guidelines in elderly patients with diabetes and predictors of such appropriate ACE-inhibitor or ARB use...
  20. pmc Prevalence, incidence, and demographics of systemic lupus erythematosus and lupus nephritis from 2000 to 2004 among children in the US Medicaid beneficiary population
    Linda T Hiraki
    Harvard School of Public Health and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arthritis Rheum 64:2669-76. 2012
    ..To investigate the nationwide prevalence, incidence, and sociodemographics of systemic lupus erythematosus (SLE) and lupus nephritis among children in the US Medicaid beneficiary population...
  21. pmc End-stage renal disease due to lupus nephritis among children in the US, 1995-2006
    Linda T Hiraki
    Harvard School of Public Health and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arthritis Rheum 63:1988-97. 2011
    ..To identify predictors of wait-listing for kidney transplantation, kidney transplantation, and mortality among children with lupus nephritis-associated end-stage renal disease (ESRD)...
  22. doi Impact of reimbursement changes on statin use among patients with diabetes in Austria
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Wien Klin Wochenschr 122:89-94. 2010
    ..These have used various instruments to steer appropriate use of such treatment. It was the purpose of this study to examine the effect of two reimbursement policy changes of statin therapy in patients with diabetes in Austria...
  23. ncbi Associations between MTHFR 1793G>A and plasma total homocysteine, folate, and vitamin B in kidney transplant recipients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 67:1980-5. 2005
    ....
  24. ncbi Use and safety of heparin-free maintenance hemodialysis in the USA
    Jenny I Shen
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA
    Nephrol Dial Transplant 28:1589-602. 2013
    ..We describe the determinants of heparin-free HD and its association with adverse outcomes using data from a national dialysis provider merged with Medicare claims...
  25. pmc Trends in the incidence, demographics, and outcomes of end-stage renal disease due to lupus nephritis in the US from 1995 to 2006
    Karen H Costenbader
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Arthritis Rheum 63:1681-8. 2011
    ....
  26. pmc Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patients
    Niteesh K Choudhry
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Pharmacoepidemiol Drug Saf 17:1189-96. 2008
    ..Poor levels of medication adherence for patients with coronary heart disease (CHD) have been documented but it is unclear whether adherence has improved over time...
  27. doi Gender differences in the management and prognosis of myocardial infarction among patients > or = 65 years of age
    Soko Setoguchi
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 101:1531-6. 2008
    ..Men, especially those aged > or =75 years, however, had worse short- and long-term prognoses compared with women of a similar age. The mortality was highest and the gender effect was more pronounced during the MI hospitalizations...
  28. doi Altitude and all-cause mortality in incident dialysis patients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Ste 3 030, Boston, MA 02120, USA
    JAMA 301:508-12. 2009
    ..Increased iron availability caused by activation of hypoxia-induced factors at higher altitude may explain this finding. Hypoxia-induced factors are also involved in other pathways that may affect morbidity and mortality...
  29. pmc Use of secondary prevention medications among adults with reduced kidney function
    Tara I Chang
    Division of Nephrology, Department of Medicine, Stanford University, Palo Alto, California, USA
    Clin J Am Soc Nephrol 7:604-11. 2012
    ....
  30. ncbi Nephrologist care and mortality in patients with chronic renal insufficiency
    Jerry Avorn
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 162:2002-6. 2002
    ..We sought to determine whether early or frequent access to nephrologist care prior to the initiation of dialysis was associated with a difference in mortality rates in the first year after dialysis began...
  31. ncbi Ten-year trends of cardiovascular drug use after myocardial infarction among community-dwelling persons > or =65 years of age
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 100:1061-7. 2007
    ..The underuse of statins and BBs was marked in black patients and did not improve over time...
  32. pmc Use of recommended medications after myocardial infarction in Austria
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Eur J Epidemiol 23:153-62. 2008
    ..001). We conclude that recommended medications were underused in Austrian MI survivors. Quality indicators should be established and interventions be implemented to ensure maximum secondary prevention after MI...
  33. ncbi Fasting plasma total homocysteine levels and mortality and allograft loss in kidney transplant recipients: a prospective study
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    J Am Soc Nephrol 16:255-60. 2005
    ..The clinical utility of homocysteine-lowering therapy, such as multivitamin therapy, to reduce the rates of these end points needs to be studied...
  34. pmc Angiotensin inhibition after myocardial infarction: does drug class matter?
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    J Gen Intern Med 21:1242-7. 2006
    ..Little is known about their relative use after MI in typical care settings, and about their relative effectiveness outside the clinical trial setting...
  35. doi ACE inhibitor and angiotensin II type 1 receptor antagonist therapies in elderly patients with diabetes mellitus: are they underutilized?
    Lamioko Shika Pappoe
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Drugs Aging 27:87-94. 2010
    ....
  36. pmc Risk factors of short-term mortality after acute nonvariceal upper gastrointestinal bleeding in patients on dialysis: a population-based study
    Ju Yeh Yang
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, 1070 Arastradero Rd, Suite 313, Palo Alto, CA 94304, USA
    BMC Nephrol 14:97. 2013
    ..We examined the associations among demographic characteristics, dialysis-specific features, and comorbid conditions with short-term mortality after ANVUGIB among patients on dialysis...
  37. doi Trends in the incidence of intestinal perforation in US dialysis patients (1992-2005)
    Ju Yeh Yang
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, California, USA
    J Nephrol 26:281-8. 2013
    ..Concerns exist that sevelamer hydrochloride may increase the risk of intestinal perforation. We examined long-term trends for the incidence of intestinal perforation among US dialysis patients...
  38. pmc Trends in acute nonvariceal upper gastrointestinal bleeding in dialysis patients
    Ju Yeh Yang
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    J Am Soc Nephrol 23:495-506. 2012
    ..Although 30-day mortality related to upper GI bleeding declined, perhaps reflecting improvements in medical care, the burden on the ESRD population remains substantial...
  39. pmc Trends in the incidence of atrial fibrillation in older patients initiating dialysis in the United States
    Benjamin A Goldstein
    Division of General Medical Disciplines, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Circulation 126:2293-301. 2012
    ..One sixth of US dialysis patients 65 years of age have been diagnosed with atrial fibrillation/flutter (AF). Little is known, however, about the incidence of AF in this population...
  40. ncbi Use and safety of unfractionated heparin for anticoagulation during maintenance hemodialysis
    Jenny I Shen
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Am J Kidney Dis 60:473-86. 2012
    ..When properly monitored, UFH is a relatively safe and economical choice for anticoagulation in long-term hemodialysis for most patients...
  41. ncbi Comparing mortality of elderly patients on hemodialysis versus peritoneal dialysis: a propensity score approach
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 13:2353-62. 2002
    ....
  42. ncbi Identification of individuals with CKD from Medicare claims data: a validation study
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Am J Kidney Dis 46:225-32. 2005
    ..The validity of this approach to identify patients with CKD has not been sufficiently studied...
  43. ncbi Effects of TCN2 776C>G on vitamin B, folate, and total homocysteine levels in kidney transplant patients
    Wolfgang C Winkelmayer
    The Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 65:1877-81. 2004
    ..Controversy exists regarding the possible associations between a single nucleotide polymorphism of the transcobalamin II encoding gene (TCN2 776C>G) and plasma levels of vitamin B(12), folate, or total homocysteine...
  44. ncbi Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Boston, MA 02120, USA
    Kidney Int 68:2857-62. 2005
    ..The methylenetetrahydrofolate-reductase (MTHFR) 677C>T polymorphism, an important determinant of plasma tHcy concentrations, could therefore constitute an important prognostic marker...
  45. pmc Preventive health care measures before and after start of renal replacement therapy
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    J Gen Intern Med 17:588-95. 2002
    ..To describe utilization of preventive health care measures in patients with chronic kidney disease (CKD), both in the year prior to onset of renal replacement therapy (RRT), and in the first year of RRT...
  46. pmc HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival
    Nizar Younas
    Department of Medicine, Renal Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Nephrol 11:5. 2010
    ..We evaluated the predictors of statin use following kidney transplantation and examined its association with patient and allograft survival...
  47. ncbi Assessing health state utilities in elderly patients at cardiovascular risk
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Med Decis Making 26:247-54. 2006
    ..Health state preferences can be a crucial component of cost-effectiveness analyses, but off-the-shelf health state utilities specifically for older people are not available...
  48. ncbi Kidney function and use of recommended medications after myocardial infarction in elderly patients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    Clin J Am Soc Nephrol 1:796-801. 2006
    ..Differences in other characteristics such as age, rather than kidney function, may be responsible for much or all the reported reduction in use of preventive medications after MI seen in patients with chronic kidney disease...
  49. pmc Variation in nephrologist visits to patients on hemodialysis across dialysis facilities and geographic locations
    Kevin F Erickson
    Department of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Clin J Am Soc Nephrol 8:987-94. 2013
    ....
  50. ncbi Comparison of Medicare claims versus physician adjudication for identifying stroke outcomes in the Women's Health Initiative
    Kamakshi Lakshminarayan
    From the Divisions of Epidemiology and Community Health K L, C F and Health Services Research and Policy B V, University of Minnesota School of Public Health, Minneapolis, MN Women s Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, Seattle, WA J C L Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL N B A Division of Cardiovascular Medicine, University of Florida, Gainesville, FL M L Department of Medicine, Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA W C W Department of Medicine, Division of Preventive Medicine, University of Alabama, Birmingham, AL M M S and National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD D R B
    Stroke 45:815-21. 2014
    ..This is resource-intensive. Herein, we assess whether Medicare data can reliably assess stroke events in the WHI...
  51. pmc Determinants of peritoneal dialysis technique failure in incident US patients
    Jenny I Shen
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Suite 106, Palo Alto, California 94305, USA
    Perit Dial Int 33:155-66. 2013
    ..We used Cox regression to examine associations between technique failure and demographic, medical, social, and pre-dialysis factors. We estimated hazard ratios (HRs) with 95% confidence intervals (CIs)...
  52. ncbi Trends in acute kidney injury, associated use of dialysis, and mortality after cardiac surgery, 1999 to 2008
    Colin R Lenihan
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    Ann Thorac Surg 95:20-8. 2013
    ..The last decade has seen major changes in the complexity of cardiac surgical candidates and in the number and type of cardiac surgical procedures being performed...
  53. pmc The effect of altitude on dosing and response to erythropoietin in ESRD
    M Alan Brookhart
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    J Am Soc Nephrol 19:1389-95. 2008
    ..Furthermore, resistance to EPO decreased with elevation. Our results suggest that ESRD patients living at high altitude either increase endogenous EPO production or respond better to endogenous and exogenous EPO...
  54. ncbi Analysis of the cardiovascular risk profile in stable kidney transplant recipients after 50% cyclosporine reduction
    Waichi Wong
    Transplantation Unit, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
    Clin Transplant 18:341-8. 2004
    ..Hence, a reduction in CsA dosage in kidney transplant recipients (KTR) may improve long-term outcomes. We analyzed the effects of 50% CsA dose reduction on the CVD risk profile in stable KTR...
  55. doi Medication issues in older individuals with CKD
    Dena E Rifkin
    Veterans Affairs Medical Center, San Diego, CA, USA
    Adv Chronic Kidney Dis 17:320-8. 2010
    ..In this review, we outline the risks and benefits of medication use in the CKD population as a specific case within geriatric pharmacoepidemiology as a framework...
  56. ncbi Strategies for the management of suspected heparin-induced thrombocytopenia: a cost-effectiveness analysis
    Amanda R Patrick
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham, Massachusetts 02120, USA
    Pharmacoeconomics 25:949-61. 2007
    ..Drugs used to treat HIT are costly and may carry an increased risk of bleeding...
  57. ncbi Hetastarch and bleeding complications after coronary artery surgery
    Jerry Avorn
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Chest 124:1437-42. 2003
    ..To determine whether intraoperative HES use is associated with an increased risk of postoperative bleeding following coronary artery bypass graft (CABG) surgery...
  58. doi Trends in the use and outcomes of implantable cardioverter-defibrillators in patients undergoing dialysis in the United States
    David M Charytan
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Am J Kidney Dis 58:409-17. 2011
    ..Sudden cardiac death constitutes the leading cause of death in patients receiving dialysis. Little is known about the trends in implantable cardioverter-defibrillator (ICD) use and the outcomes of such device placement...
  59. ncbi Trends in relative mortality between Hispanic and non-Hispanic whites initiating dialysis: a retrospective study of the US Renal Data System
    Cristina M Arce
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
    Am J Kidney Dis 62:312-21. 2013
    ..It is unknown whether this association differs by age, has changed over time, or is due to differential access to kidney transplantation...
  60. ncbi Early erythropoietin therapy is associated with improved growth in children with chronic kidney disease
    Michael Boehm
    Kinderdialyse, Department of Pediatrics, Medical University Vienna, Vienna, Austria, and Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Pediatr Nephrol 22:1189-93. 2007
    ..Almost two thirds of referred children, however, experienced no catch-up growth during follow-up. Further study is needed to better define the optimal timing and intensity of nephrologist care in children with kidney disease...
  61. ncbi Percentage of hypochromic red blood cells is an independent risk factor for mortality in kidney transplant recipients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Transplant 4:2075-81. 2004
    ..Larger studies on the association between anemia and these outcomes are warranted...
  62. ncbi A J-shaped association between high-sensitivity C-reactive protein and mortality in kidney transplant recipients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Transpl Int 20:505-11. 2007
    ..In contrast to the general population, the association between hs-CRP and mortality in KTRs is not linear, but J-shaped, suggesting that KTRs with very low hs-CRP may also be at increased risk of death...
  63. doi Comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapy
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
    Arch Intern Med 168:2368-75. 2008
    ..We compared cardiovascular outcomes and mortality between patients initiating pioglitazone vs rosiglitazone therapy...
  64. ncbi Health economic evaluations: the special case of end-stage renal disease treatment
    Wolfgang C Winkelmayer
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Med Decis Making 22:417-30. 2002
    ..Uses of the cost-effectiveness ratio of $55,000/LY for center hemodialysis as a lower boundary of society's willingness to pay for an additional life-year can be supported under certain assumptions...
  65. pmc Preoperative statin use and postoperative acute kidney injury
    Steven M Brunelli
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Am J Med 125:1195-1204.e3. 2012
    ..The purpose of this study was to evaluate whether preoperative statin use is associated with a decreased risk of postoperative acute kidney injury...
  66. ncbi Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure
    Sushrut S Waikar
    Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Am Soc Nephrol 17:1688-94. 2006
    ..The excellent performance characteristics of ICD-9-CM codes for ARF-D suggest that administrative data sets may be particularly well suited for research endeavors that involve patients with ARF-D...
  67. pmc Kidney function and long-term medication adherence after myocardial infarction in the elderly
    Tara I Chang
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, California, USA
    Clin J Am Soc Nephrol 6:864-9. 2011
    ..The association of kidney function with long-term outpatient medication adherence in the elderly remains understudied...
  68. doi Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injury
    Wolfgang C Winkelmayer
    The Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Am J Med 121:1092-8. 2008
    ..We undertook a large pharmacoepidemiologic analysis of the risk of acute kidney injury among older adults using nonselective NSAIDs or cyclooxygenase (COX)-2 inhibitors...
  69. ncbi Genetic aspects of hyperhomocysteinemia in chronic kidney disease
    Gere Sunder-Plassmann
    Department of Medicine III, Medical University Vienna, Vienna, Austria, and the Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Semin Nephrol 26:8-13. 2006
    ....
  70. ncbi C-reactive protein and body mass index independently predict mortality in kidney transplant recipients
    Wolfgang C Winkelmayer
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Transplant 4:1148-54. 2004
    ..Furthermore, we were not able to detect any effect modification between CRP and body mass index on the outcomes under study. We conclude that CRP predicts all-cause mortality, but not allograft loss in stable KTR...
  71. ncbi Comparison of two dosages of thymoglobulin used as a short-course for induction in kidney transplantation
    Waichi Wong
    Renal and Transplantation Units, Massachusetts General Hospital and Harvard Medical School Boston, Boston, MA 02114, USA
    Transpl Int 19:629-35. 2006
    ..5 mg/kg/day regimen. A more profound T-cell clearance within the first 6 months postinduction therapy may translate into a decreased risk of immunological injury and improved long-term outcome after kidney transplantation...
  72. ncbi Pharmacoepidemiology of anemia in kidney transplant recipients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Am Soc Nephrol 15:1347-52. 2004
    ..05) and tacrolimus (P = 0.02) were associated with a lower HCT. The authors conclude that PTA is prevalent and undertreated in KTR. Several medications that are possibly modifiable correlates of PTR deserve further study...
  73. pmc A randomized, double-blind, placebo-controlled trial of calcium acetate on serum phosphorus concentrations in patients with advanced non-dialysis-dependent chronic kidney disease
    Wajeh Qunibi
    Department of Medicine, University of Texas Health Sciences Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    BMC Nephrol 12:9. 2011
    ..This trial was conducted to examine the efficacy and safety of calcium acetate in controlling serum phosphorus in pre-dialysis patients with CKD...
  74. ncbi Impact of Medicaid prior authorization on angiotensin-receptor blockers: can policy promote rational prescribing?
    Michael A Fischer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts, USA
    Health Aff (Millwood) 26:800-7. 2007
    ..3 percent per quarter; alternative approaches were unsuccessful. These findings have important implications for the development of rational drug reimbursement policy under Medicare Part D and other health insurance plans...
  75. ncbi Hydroxyethyl starch and change in renal function in patients undergoing coronary artery bypass graft surgery
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 64:1046-9. 2003
    ..We sought to study the question in a formal analysis of postoperative change in renal function in patients undergoing coronary artery bypass graft (CABG) surgery...
  76. ncbi Poor short-term survival and low use of cardiovascular medications in elderly dialysis patients after acute myocardial infarction
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Am J Kidney Dis 47:301-8. 2006
    ..Their use and association with mortality in elderly dialysis patients after MI have not been studied sufficiently...
  77. ncbi The nephrologist's role in the management of calcium-phosphorus metabolism in patients with chronic kidney disease
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 63:1836-42. 2003
    ..In patients with chronic kidney disease (CKD), timely referral to a nephrologist has been shown to improve outcomes, but the specific care measures mediating these superior outcomes have not been sufficiently described...
  78. ncbi Angiotensin-converting enzyme inhibitors and cardiovascular outcomes in patients on maintenance hemodialysis
    Tara I Chang
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    Am Heart J 162:324-30. 2011
    ..Angiotensin-converting enzyme inhibitors (ACEIs) are recommended for patients on dialysis, but there are few data regarding their effectiveness in ESRD...
  79. ncbi Renal dysfunction increases the risk of saphenous vein graft occlusion: results from the Post-CABG trial
    Gregory A Wellenius
    Cardiovascular Epidemiology Research Unit, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Deaconess 306, Boston, MA 02215, USA
    Atherosclerosis 193:414-20. 2007
    ..Saphenous vein grafts are common among patients with a history of coronary artery bypass graft (CABG) surgery. Chronic kidney disease (CKD) is an established cardiovascular risk factor, but its role in graft disease has not been evaluated...
  80. pmc Pottransplantation anemia: management and rationale
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3 030, Boston, MA 02120, USA
    Clin J Am Soc Nephrol 3:S49-55. 2008
    ..Given the lack of large, well-designed, prospective studies, the consequences of anemia, the response to treatment, and the cost-effectiveness of treatment in the posttransplantation setting are also poorly understood...
  81. ncbi Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniors
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, United States
    Int J Cardiol 125:172-7. 2008
    ..Little is known about recent trends in the use of ACEI/ARB in community-dwelling seniors...
  82. ncbi A prospective study of anaemia and long-term outcomes in kidney transplant recipients
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    Nephrol Dial Transplant 21:3559-66. 2006
    ..However, no evidence is currently available that anaemia is actually associated with such risks in KTR...
  83. ncbi Nononcologic use of human recombinant erythropoietin therapy in hospitalized patients
    Michael A Fischer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    Arch Intern Med 167:840-6. 2007
    ..Little is known about the nature of rHuEPO use in hospitalized patients who receive rHuEPO therapy for nononcologic indications...
  84. doi Posttransplantation anemia: mechanisms and management
    Julie M Yabu
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
    Clin J Am Soc Nephrol 6:1794-801. 2011
    ..This article reviews the prevalence, pathogenesis, and management of anemia in kidney transplant recipients...
  85. ncbi How well do patients report noncompliance with antihypertensive medications?: a comparison of self-report versus filled prescriptions
    Philip S Wang
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 13:11-9. 2004
    ..Although self-reports are often the only means available in routine practice, their accuracy and agreement with other data sources remain questionable...
  86. ncbi Efficacy and safety of angiotensin II receptor blockade in elderly patients with diabetes
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, MA 02120, USA
    Diabetes Care 29:2210-7. 2006
    ....
  87. ncbi Habitual caffeine intake and the risk of hypertension in women
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    JAMA 294:2330-5. 2005
    ..Caffeine acutely increases blood pressure, but the association between habitual consumption of caffeinated beverages and incident hypertension is uncertain...
  88. doi Incidence, correlates, and consequences of acute kidney injury in patients with pulmonary arterial hypertension hospitalized with acute right-side heart failure
    Francois Haddad
    Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    J Card Fail 17:533-9. 2011
    ..Though much is known about the prognostic influence of acute kidney injury (AKI) in left-side heart failure, much less is known about AKI in patients with pulmonary arterial hypertension (PAH)...