Research Topics
Genomes and GenesSpecies | Wolfgang C WinkelmayerSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Propensity scores in the presence of effect modification: A case study using the comparison of mortality on hemodialysis versus peritoneal dialysisYlian S Liem
Program for the Assessment of Radiological Technology ART Program, Department of Epidemiology and Biostatistics and the Department of Radiology, Erasmus University Medical Center Rotterdam, Dr, Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
Emerg Themes Epidemiol 7:1. 2010..Our aim was to compare a propensity score-stratified model with a traditional multivariable-adjusted model, specifically in estimating survival of hemodialysis (HD) versus peritoneal dialysis (PD) patients...- Risk factors of short-term mortality after acute nonvariceal upper gastrointestinal bleeding in patients on dialysis: a population-based studyJu Yeh Yang
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, 1070 Arastradero Rd, Suite 313, Palo Alto, CA, 94304, USA
BMC Nephrol 14:97. 2013..We examined the associations among demographic characteristics, dialysis-specific features, and comorbid conditions with short-term mortality after ANVUGIB among patients on dialysis... 
Predialyis nephrology care of older individuals approaching end-stage renal diseaseWolfgang C Winkelmayer
Division of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
Semin Dial 25:628-32. 2012..Defining the appropriate role and involvement of nephrologists in the decision about initiating renal replacement therapy in older adults seems ripe for further investigation and discussion...- Prevalence of atrial fibrillation and warfarin use in older patients receiving hemodialysisWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Nephrol 25:341-53. 2012..Little is known about the use of warfarin in hemodialysis (HD) patients with atrial fibrillation (AF). We studied temporal trends of AF among older HD patients, and of warfarin use among those with AF... 
Comparative effectiveness research: what is it and why do we need it in nephrology?Tara I Chang
Nephrol Dial Transplant 27:2156-61. 2012..Finally, we will discuss why CER pertaining to kidney disease care needs to be a top priority in order to move our field from a largely opinion-based specialty to an evidence-based specialty...- Altitude and the risk of cardiovascular events in incident US dialysis patientsWolfgang C Winkelmayer
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA
Nephrol Dial Transplant 27:2411-7. 2012..We hypothesized that higher altitude would be associated with lower rates of cardiovascular events due to an altered physiological response of dialysis patients to altitude induced hypoxia... - The increasing prevalence of atrial fibrillation among hemodialysis patientsWolfgang C Winkelmayer
Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Suite 106, Palo Alto, CA 94304, USA
J Am Soc Nephrol 22:349-57. 2011..Identifying potentially modifiable risk factors for incident atrial fibrillation requires further investigation... - Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillationWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin J Am Soc Nephrol 6:2662-8. 2011..Although generally recommended in atrial fibrillation (AF) patients, the effectiveness and safety of oral anticoagulation in dialysis patients with AF is unknown... - Predialysis nephrology care of older patients approaching end-stage renal diseaseWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Arch Intern Med 171:1371-8. 2011..Little is known about trends in the timing of first nephrology consultation and associated outcomes among older patients initiating dialysis... - Comparative effectiveness of calcium-containing phosphate binders in incident U.S. dialysis patientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin J Am Soc Nephrol 6:175-83. 2011..We studied the association between use versus nonuse of calcium-containing phosphate binders (CCPBs) and mortality from any cause. We also tested whether mortality differed among users of individual CCPBs... - Potential effects of the new Medicare Prospective Payment System on drug prescription in end-stage renal disease careWolfgang C Winkelmayer
Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Palo Alto, CA 94304, USA
Blood Purif 31:66-9. 2011..On aggregate, these changes have the potential to alter patient outcomes, but it is currently unclear how these will be and can be monitored... - Guideline-conformity of initiation with oral hypoglycemic treatment for patients with newly therapy-dependent type 2 diabetes mellitus in AustriaWolfgang C Winkelmayer
Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
Pharmacoepidemiol Drug Saf 20:57-65. 2011..To determine guideline conformity of initiation of oral hypoglycemic (OH) treatment for type 2 diabetes in Austria; to study patient and prescriber correlates of recommended initiation with metformin monotherapy... - Confusion about the appropriate use of erythropoiesis-stimulating agents in patients undergoing maintenance dialysisWolfgang C Winkelmayer
Division of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
Semin Dial 23:486-91. 2010.... - Variation in initial kidney replacement therapy for end-stage renal disease due to lupus nephritis in the United StatesAmy Devlin
Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Arthritis Care Res (Hoboken) 63:1642-53. 2011..We aimed to identify sociodemographic and clinical factors associated with variation in initial kidney replacement therapies among LN ESRD patients... - Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004Candace H Feldman
Brigham and Women s Hospital, Boston, Massachusetts
Arthritis Rheum 65:753-63. 2013..This study was undertaken to investigate the epidemiology and sociodemographics of SLE and LN in the low-income US Medicaid population... - Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysisSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Coll Cardiol 51:1247-54. 2008..We sought to assess the relationship between increasing use of cardiovascular medications and trends in long-term prognosis after myocardial infarction (MI) in the elderly... - Associations of kidney function with cardiovascular medication use after myocardial infarctionWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
Clin J Am Soc Nephrol 3:1415-22. 2008..It is unknown whether adherence to recommended medications after myocardial infarction (MI) differs by kidney function... - Validation of reported predialysis nephrology care of older patients initiating dialysisJane Paik Kim
Division of Nephrology, Stanford University School of Medicine, 780 Welch Road, Palo Alto, CA 94304, USA
J Am Soc Nephrol 23:1078-85. 2012..More-specific instructions may improve reporting and increase the utility of form CMS-2728 for research and public health surveillance... - A propensity analysis of late versus early nephrologist referral and mortality on dialysisWolfgang C Winkelmayer
Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Am Soc Nephrol 14:486-92. 2003..Further research is needed to identify patients at particular risk so that interventions to prevent early deaths on dialysis in LR patients can be developed and tested... - Underuse of ACE inhibitors and angiotensin II receptor blockers in elderly patients with diabetesWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am J Kidney Dis 46:1080-7. 2005..However, little is known about the adequacy of adherence to these guidelines in elderly patients with diabetes and predictors of such appropriate ACE-inhibitor or ARB use... - Prevalence, incidence, and demographics of systemic lupus erythematosus and lupus nephritis from 2000 to 2004 among children in the US Medicaid beneficiary populationLinda T Hiraki
Harvard School of Public Health and Brigham and Women s Hospital, Boston, Massachusetts, USA
Arthritis Rheum 64:2669-76. 2012..To investigate the nationwide prevalence, incidence, and sociodemographics of systemic lupus erythematosus (SLE) and lupus nephritis among children in the US Medicaid beneficiary population... - Impact of reimbursement changes on statin use among patients with diabetes in AustriaWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Wien Klin Wochenschr 122:89-94. 2010..These have used various instruments to steer appropriate use of such treatment. It was the purpose of this study to examine the effect of two reimbursement policy changes of statin therapy in patients with diabetes in Austria... - Associations between MTHFR 1793G>A and plasma total homocysteine, folate, and vitamin B in kidney transplant recipientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Kidney Int 67:1980-5. 2005.... - End-stage renal disease due to lupus nephritis among children in the US, 1995-2006Linda T Hiraki
Harvard School of Public Health and Brigham and Women s Hospital, Boston, Massachusetts, USA
Arthritis Rheum 63:1988-97. 2011..To identify predictors of wait-listing for kidney transplantation, kidney transplantation, and mortality among children with lupus nephritis-associated end-stage renal disease (ESRD)... - Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patientsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Pharmacoepidemiol Drug Saf 17:1189-96. 2008..Poor levels of medication adherence for patients with coronary heart disease (CHD) have been documented but it is unclear whether adherence has improved over time... - Trends in the incidence, demographics, and outcomes of end-stage renal disease due to lupus nephritis in the US from 1995 to 2006Karen H Costenbader
Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Arthritis Rheum 63:1681-8. 2011.... - Gender differences in the management and prognosis of myocardial infarction among patients > or = 65 years of ageSoko Setoguchi
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 101:1531-6. 2008..Men, especially those aged > or =75 years, however, had worse short- and long-term prognoses compared with women of a similar age. The mortality was highest and the gender effect was more pronounced during the MI hospitalizations... - Altitude and all-cause mortality in incident dialysis patientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Ste 3 030, Boston, MA 02120, USA
JAMA 301:508-12. 2009..Increased iron availability caused by activation of hypoxia-induced factors at higher altitude may explain this finding. Hypoxia-induced factors are also involved in other pathways that may affect morbidity and mortality... - Use of secondary prevention medications among adults with reduced kidney functionTara I Chang
Division of Nephrology, Department of Medicine, Stanford University, Palo Alto, California, USA
Clin J Am Soc Nephrol 7:604-11. 2012.... - Nephrologist care and mortality in patients with chronic renal insufficiencyJerry Avorn
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Arch Intern Med 162:2002-6. 2002..These findings need to be confirmed in younger and less indigent patients as well... - Ten-year trends of cardiovascular drug use after myocardial infarction among community-dwelling persons > or =65 years of ageSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 100:1061-7. 2007..The underuse of statins and BBs was marked in black patients and did not improve over time... - ACE inhibitor and angiotensin II type 1 receptor antagonist therapies in elderly patients with diabetes mellitus: are they underutilized?Lamioko Shika Pappoe
Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Drugs Aging 27:87-94. 2010.... - Use of recommended medications after myocardial infarction in AustriaWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Eur J Epidemiol 23:153-62. 2008..001). We conclude that recommended medications were underused in Austrian MI survivors. Quality indicators should be established and interventions be implemented to ensure maximum secondary prevention after MI... - Angiotensin inhibition after myocardial infarction: does drug class matter?Wolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
J Gen Intern Med 21:1242-7. 2006..Little is known about their relative use after MI in typical care settings, and about their relative effectiveness outside the clinical trial setting... - Fasting plasma total homocysteine levels and mortality and allograft loss in kidney transplant recipients: a prospective studyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
J Am Soc Nephrol 16:255-60. 2005..The clinical utility of homocysteine-lowering therapy, such as multivitamin therapy, to reduce the rates of these end points needs to be studied... - Trends in acute nonvariceal upper gastrointestinal bleeding in dialysis patientsJu Yeh Yang
Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
J Am Soc Nephrol 23:495-506. 2012..Although 30-day mortality related to upper GI bleeding declined, perhaps reflecting improvements in medical care, the burden on the ESRD population remains substantial... - Trends in the incidence of atrial fibrillation in older patients initiating dialysis in the United StatesBenjamin A Goldstein
Division of General Medical Disciplines, Stanford University School of Medicine, Palo Alto, CA 94304, USA
Circulation 126:2293-301. 2012..One sixth of US dialysis patients 65 years of age have been diagnosed with atrial fibrillation/flutter (AF). Little is known, however, about the incidence of AF in this population... - Use and safety of unfractionated heparin for anticoagulation during maintenance hemodialysisJenny I Shen
Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
Am J Kidney Dis 60:473-86. 2012..When properly monitored, UFH is a relatively safe and economical choice for anticoagulation in long-term hemodialysis for most patients... - Identification of individuals with CKD from Medicare claims data: a validation studyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Am J Kidney Dis 46:225-32. 2005..The validity of this approach to identify patients with CKD has not been sufficiently studied... - Comparing mortality of elderly patients on hemodialysis versus peritoneal dialysis: a propensity score approachWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Soc Nephrol 13:2353-62. 2002.... - Kidney function and use of recommended medications after myocardial infarction in elderly patientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Clin J Am Soc Nephrol 1:796-801. 2006..Differences in other characteristics such as age, rather than kidney function, may be responsible for much or all the reported reduction in use of preventive medications after MI seen in patients with chronic kidney disease... - Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Boston, MA 02120, USA
Kidney Int 68:2857-62. 2005..The methylenetetrahydrofolate-reductase (MTHFR) 677C>T polymorphism, an important determinant of plasma tHcy concentrations, could therefore constitute an important prognostic marker... - HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survivalNizar Younas
Department of Medicine, Renal Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USA
BMC Nephrol 11:5. 2010..We evaluated the predictors of statin use following kidney transplantation and examined its association with patient and allograft survival... - Preventive health care measures before and after start of renal replacement therapyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
J Gen Intern Med 17:588-95. 2002..To describe utilization of preventive health care measures in patients with chronic kidney disease (CKD), both in the year prior to onset of renal replacement therapy (RRT), and in the first year of RRT... - Assessing health state utilities in elderly patients at cardiovascular riskWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Med Decis Making 26:247-54. 2006..Health state preferences can be a crucial component of cost-effectiveness analyses, but off-the-shelf health state utilities specifically for older people are not available... - Effects of TCN2 776C>G on vitamin B, folate, and total homocysteine levels in kidney transplant patientsWolfgang C Winkelmayer
The Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Kidney Int 65:1877-81. 2004..Controversy exists regarding the possible associations between a single nucleotide polymorphism of the transcobalamin II encoding gene (TCN2 776C>G) and plasma levels of vitamin B(12), folate, or total homocysteine... - Trends in acute kidney injury, associated use of dialysis, and mortality after cardiac surgery, 1999 to 2008Colin R Lenihan
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
Ann Thorac Surg 95:20-8. 2013..The last decade has seen major changes in the complexity of cardiac surgical candidates and in the number and type of cardiac surgical procedures being performed... - The effect of altitude on dosing and response to erythropoietin in ESRDM Alan Brookhart
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
J Am Soc Nephrol 19:1389-95. 2008..Furthermore, resistance to EPO decreased with elevation. Our results suggest that ESRD patients living at high altitude either increase endogenous EPO production or respond better to endogenous and exogenous EPO... - Analysis of the cardiovascular risk profile in stable kidney transplant recipients after 50% cyclosporine reductionWaichi Wong
Transplantation Unit, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
Clin Transplant 18:341-8. 2004..Hence, a reduction in CsA dosage in kidney transplant recipients (KTR) may improve long-term outcomes. We analyzed the effects of 50% CsA dose reduction on the CVD risk profile in stable KTR... - Medication issues in older individuals with CKDDena E Rifkin
Veterans Affairs Medical Center, San Diego, CA, USA
Adv Chronic Kidney Dis 17:320-8. 2010..In this review, we outline the risks and benefits of medication use in the CKD population as a specific case within geriatric pharmacoepidemiology as a framework... - Strategies for the management of suspected heparin-induced thrombocytopenia: a cost-effectiveness analysisAmanda R Patrick
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham, Massachusetts 02120, USA
Pharmacoeconomics 25:949-61. 2007..Drugs used to treat HIT are costly and may carry an increased risk of bleeding... - Trends in the use and outcomes of implantable cardioverter-defibrillators in patients undergoing dialysis in the United StatesDavid M Charytan
Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Kidney Dis 58:409-17. 2011..Sudden cardiac death constitutes the leading cause of death in patients receiving dialysis. Little is known about the trends in implantable cardioverter-defibrillator (ICD) use and the outcomes of such device placement... - Hetastarch and bleeding complications after coronary artery surgeryJerry Avorn
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Chest 124:1437-42. 2003..To determine whether intraoperative HES use is associated with an increased risk of postoperative bleeding following coronary artery bypass graft (CABG) surgery... - Early erythropoietin therapy is associated with improved growth in children with chronic kidney diseaseMichael Boehm
Kinderdialyse, Department of Pediatrics, Medical University Vienna, Vienna, Austria, and Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Pediatr Nephrol 22:1189-93. 2007..Almost two thirds of referred children, however, experienced no catch-up growth during follow-up. Further study is needed to better define the optimal timing and intensity of nephrologist care in children with kidney disease... - Health economic evaluations: the special case of end-stage renal disease treatmentWolfgang C Winkelmayer
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Med Decis Making 22:417-30. 2002..Uses of the cost-effectiveness ratio of $55,000/LY for center hemodialysis as a lower boundary of society's willingness to pay for an additional life-year can be supported under certain assumptions... - Percentage of hypochromic red blood cells is an independent risk factor for mortality in kidney transplant recipientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am J Transplant 4:2075-81. 2004..Larger studies on the association between anemia and these outcomes are warranted... - Comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
Arch Intern Med 168:2368-75. 2008..We compared cardiovascular outcomes and mortality between patients initiating pioglitazone vs rosiglitazone therapy... - A J-shaped association between high-sensitivity C-reactive protein and mortality in kidney transplant recipientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Transpl Int 20:505-11. 2007..In contrast to the general population, the association between hs-CRP and mortality in KTRs is not linear, but J-shaped, suggesting that KTRs with very low hs-CRP may also be at increased risk of death... - Preoperative statin use and postoperative acute kidney injurySteven M Brunelli
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Am J Med 125:1195-1204.e3. 2012..The purpose of this study was to evaluate whether preoperative statin use is associated with a decreased risk of postoperative acute kidney injury... - Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal FailureSushrut S Waikar
Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Am Soc Nephrol 17:1688-94. 2006..The excellent performance characteristics of ICD-9-CM codes for ARF-D suggest that administrative data sets may be particularly well suited for research endeavors that involve patients with ARF-D... - Kidney function and long-term medication adherence after myocardial infarction in the elderlyTara I Chang
Division of Nephrology, Stanford University School of Medicine, Palo Alto, California, USA
Clin J Am Soc Nephrol 6:864-9. 2011..The association of kidney function with long-term outpatient medication adherence in the elderly remains understudied... - A randomized, double-blind, placebo-controlled trial of calcium acetate on serum phosphorus concentrations in patients with advanced non-dialysis-dependent chronic kidney diseaseWajeh Qunibi
Department of Medicine, University of Texas Health Sciences Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
BMC Nephrol 12:9. 2011..This trial was conducted to examine the efficacy and safety of calcium acetate in controlling serum phosphorus in pre-dialysis patients with CKD... - Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injuryWolfgang C Winkelmayer
The Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Am J Med 121:1092-8. 2008..We undertook a large pharmacoepidemiologic analysis of the risk of acute kidney injury among older adults using nonselective NSAIDs or cyclooxygenase (COX)-2 inhibitors... - Hydroxyethyl starch and change in renal function in patients undergoing coronary artery bypass graft surgeryWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Kidney Int 64:1046-9. 2003..We sought to study the question in a formal analysis of postoperative change in renal function in patients undergoing coronary artery bypass graft (CABG) surgery... - C-reactive protein and body mass index independently predict mortality in kidney transplant recipientsWolfgang C Winkelmayer
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am J Transplant 4:1148-54. 2004..Furthermore, we were not able to detect any effect modification between CRP and body mass index on the outcomes under study. We conclude that CRP predicts all-cause mortality, but not allograft loss in stable KTR... - Pharmacoepidemiology of anemia in kidney transplant recipientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Am Soc Nephrol 15:1347-52. 2004..05) and tacrolimus (P = 0.02) were associated with a lower HCT. The authors conclude that PTA is prevalent and undertreated in KTR. Several medications that are possibly modifiable correlates of PTR deserve further study... - Genetic aspects of hyperhomocysteinemia in chronic kidney diseaseGere Sunder-Plassmann
Department of Medicine III, Medical University Vienna, Vienna, Austria, and the Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Semin Nephrol 26:8-13. 2006.... - Comparison of two dosages of thymoglobulin used as a short-course for induction in kidney transplantationWaichi Wong
Renal and Transplantation Units, Massachusetts General Hospital and Harvard Medical School Boston, Boston, MA 02114, USA
Transpl Int 19:629-35. 2006..5 mg/kg/day regimen. A more profound T-cell clearance within the first 6 months postinduction therapy may translate into a decreased risk of immunological injury and improved long-term outcome after kidney transplantation... - Impact of Medicaid prior authorization on angiotensin-receptor blockers: can policy promote rational prescribing?Michael A Fischer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts, USA
Health Aff (Millwood) 26:800-7. 2007..3 percent per quarter; alternative approaches were unsuccessful. These findings have important implications for the development of rational drug reimbursement policy under Medicare Part D and other health insurance plans... - Poor short-term survival and low use of cardiovascular medications in elderly dialysis patients after acute myocardial infarctionWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Am J Kidney Dis 47:301-8. 2006..Their use and association with mortality in elderly dialysis patients after MI have not been studied sufficiently... - Renal dysfunction increases the risk of saphenous vein graft occlusion: results from the Post-CABG trialGregory A Wellenius
Cardiovascular Epidemiology Research Unit, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Deaconess 306, Boston, MA 02215, USA
Atherosclerosis 193:414-20. 2007..Saphenous vein grafts are common among patients with a history of coronary artery bypass graft (CABG) surgery. Chronic kidney disease (CKD) is an established cardiovascular risk factor, but its role in graft disease has not been evaluated... - The nephrologist's role in the management of calcium-phosphorus metabolism in patients with chronic kidney diseaseWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Kidney Int 63:1836-42. 2003.... - A prospective study of anaemia and long-term outcomes in kidney transplant recipientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Nephrol Dial Transplant 21:3559-66. 2006..However, no evidence is currently available that anaemia is actually associated with such risks in KTR... - Nononcologic use of human recombinant erythropoietin therapy in hospitalized patientsMichael A Fischer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
Arch Intern Med 167:840-6. 2007..Little is known about the nature of rHuEPO use in hospitalized patients who receive rHuEPO therapy for nononcologic indications... - Angiotensin-converting enzyme inhibitors and cardiovascular outcomes in patients on maintenance hemodialysisTara I Chang
Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
Am Heart J 162:324-30. 2011..Angiotensin-converting enzyme inhibitors (ACEIs) are recommended for patients on dialysis, but there are few data regarding their effectiveness in ESRD... - Pottransplantation anemia: management and rationaleWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3 030, Boston, MA 02120, USA
Clin J Am Soc Nephrol 3:S49-55. 2008..Given the lack of large, well-designed, prospective studies, the consequences of anemia, the response to treatment, and the cost-effectiveness of treatment in the posttransplantation setting are also poorly understood... - Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniorsSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, United States
Int J Cardiol 125:172-7. 2008..Little is known about recent trends in the use of ACEI/ARB in community-dwelling seniors... - Posttransplantation anemia: mechanisms and managementJulie M Yabu
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA
Clin J Am Soc Nephrol 6:1794-801. 2011..This article reviews the prevalence, pathogenesis, and management of anemia in kidney transplant recipients... - How well do patients report noncompliance with antihypertensive medications?: a comparison of self-report versus filled prescriptionsPhilip S Wang
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Pharmacoepidemiol Drug Saf 13:11-9. 2004..Although self-reports are often the only means available in routine practice, their accuracy and agreement with other data sources remain questionable... - Habitual caffeine intake and the risk of hypertension in womenWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
JAMA 294:2330-5. 2005..Caffeine acutely increases blood pressure, but the association between habitual consumption of caffeinated beverages and incident hypertension is uncertain... - Efficacy and safety of angiotensin II receptor blockade in elderly patients with diabetesWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, MA 02120, USA
Diabetes Care 29:2210-7. 2006.... - Incidence, correlates, and consequences of acute kidney injury in patients with pulmonary arterial hypertension hospitalized with acute right-side heart failureFrancois Haddad
Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
J Card Fail 17:533-9. 2011..Though much is known about the prognostic influence of acute kidney injury (AKI) in left-side heart failure, much less is known about AKI in patients with pulmonary arterial hypertension (PAH)...