Research Topics
| D M WilsonSummaryAffiliation: Stanford University Country: USA Publications
Research Grants
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Detail Information
Publications
Growth hormone and hypophosphatemic ricketsD M Wilson
Division of Pediatric Endocrinology and Diabetes, Stanford University Medical Center, CA 94305 5208, USA
J Pediatr Endocrinol Metab 13:993-8. 2000..Reported increases in phosphate concentrations following GH in XLHR are of uncertain clinical benefit. While GH appears to be safe in XLHR, long-term benefits remain unclear...
A brief review of the use and utility of growth hormone stimulation testing in the NCGS: do we need to do provocative GH testing?Darrell M Wilson
Pediatric Endocrinology and Diabetes, Stanford University, S 032 Medical Center, Stanford, CA 94305 5208, USA
Growth Horm IGF Res 15:S21-5. 2005....
Assessing weight-related biochemical cardiovascular risk factors in African-American girlsDarrell M Wilson
Stanford University School of Medicine, Stanford, California, USA
Obes Res 12:73S-83S. 2004..We examined the feasibility of obtaining fasting blood samples and report correlates of these biochemical markers in an understudied population sample...
Metformin extended release treatment of adolescent obesity: a 48-week randomized, double-blind, placebo-controlled trial with 48-week follow-upDarrell M Wilson
Division of Pediatric Endocrinology and Diabetes, Stanford University and the Lucile Packard Children s Hospital at Stanford, G 313 Medical Center, Stanford, CA 94305 5208, USA
Arch Pediatr Adolesc Med 164:116-23. 2010..Metformin has been proffered as a therapy for adolescent obesity, although long-term controlled studies have not been reported...
Progress in the treatment of childhood diabetes mellitus and obesityDarrell M Wilson
Division of Pediatric Endocrinology and Diabetes, Stanford University Medical Center, CA 94305 5208, USA
J Pediatr Endocrinol Metab 15:745-9. 2002..Obesity, an increasing problem in pediatric patients, was also addressed...
A two-center randomized controlled feasibility trial of insulin pump therapy in young children with diabetesDarrell M Wilson
Division of Pediatric Endocrinology and Diabetes, Stanford University, Stanford, California 94305 5208, USA
Diabetes Care 28:15-9. 2005....
Real-time continuous glucose monitor use and patient selection: what have we learned and where are we going?Darrell M Wilson
Stanford University, Stanford, California, USA
Diabetes Technol Ther 7:788-91. 2005
Regular monitoring of bone age is not useful in children treated with growth hormoneD M Wilson
Department of Pediatrics, Stanford University, Stanford, Cali fornia 94305 5208, USA
Pediatrics 104:1036-9. 1999..Routine monitoring of bone age during GH therapy is unnecessary. Bayley and Pinneau, bone age determination, Greulich and Pyle, predicted height, radiography, Tanner and Whitehouse...
Stanford GEMS phase 2 obesity prevention trial for low-income African-American girls: design and sample baseline characteristicsThomas N Robinson
Department of Pediatrics and Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA, USA
Contemp Clin Trials 29:56-69. 2008....
The Medtronic Minimed Gold continuous glucose monitoring system: an effective means to discover hypo- and hyperglycemia in children under 7 years of ageLaura M Gandrud
Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
Diabetes Technol Ther 9:307-16. 2007..Our goal was to assess the incidence of hypoglycemia as well as postprandial glycemic patterns in this age group utilizing continuous glucose monitoring...
Intensive diabetes management in pediatric patientsB Buckingham
Department of Pediatric Endocrinology, Stanford University, Stanford Medical Center, Room S 302, Stanford, CA 94305 5208, USA
Curr Diab Rep 1:11-8. 2001..This article provides a brief overview of the rationale for implementing intensive diabetes management in pediatric patients, and practical guidelines for implementation...
Semi-automated entry of clinical temporal-abstraction knowledgeY Shahar
Stanford Medical Informatics, Stanford University, California 94305 5479, USA
J Am Med Inform Assoc 6:494-511. 1999..The authors discuss the usability of an automated tool that supports entry, by clinical experts, of the knowledge necessary for forming high-level concepts and patterns from raw time-oriented clinical data...
Prospective study of risk factors for the initiation of cigarette smokingJ D Killen
Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA
J Consult Clin Psychol 65:1011-6. 1997..The data suggest that future research is needed to examine potential gender differences that may have implications for the next generation of smoking-prevention programs...
Weight concerns influence the development of eating disorders: a 4-year prospective studyJ D Killen
Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA
J Consult Clin Psychol 64:936-40. 1996..This finding is consistent with both theoretical and clinical perspectives and may represent a useful step toward the establishment of a rational basis for the choice of a prevention intervention target...
Sequential comparisons of one-month and three-month depot leuprolide regimens in central precocious pubertyAngela Badaru
Division of Pediatric Endocrinology and Diabetes, Stanford University, Stanford, California 94305, USA
J Clin Endocrinol Metab 91:1862-7. 2006..Whether various DL doses lead to long-term therapeutic differences remains to be determined...
Definition of metabolic syndrome in preadolescent girlsCarolyn H Chi
Department of Pediatrics, Stanford University and the Lucile Packard Children s Hospital at Stanford, Stanford Prevention Research Center, Stanford, California 94305 5208, USA
J Pediatr 148:788-792. 2006..To compare and contrast proposed definitions of metabolic syndrome in pediatrics, and to determine prevalence of metabolic syndrome in preadolescent females when applying different criteria...
Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unitKupper A Wintergerst
Department of Pediatrics, Pediatric Endocrinology and Diabetes, Stanford University, S 302 Medical Center, Stanford, California 94305 5208, USA
Pediatrics 118:173-9. 2006..We evaluated retrospectively plasma glucose levels and the degree of hypoglycemia, hyperglycemia, and glucose variability in a PICU and then assessed their association with hospital length of stay and mortality rates...
Real-time continuous glucose monitoringBruce Buckingham
Department of Pediatric Endocrinology, Stanford Medical Center, Stanford, California 94305 5208, USA
Curr Opin Endocrinol Diabetes Obes 14:288-95. 2007..To summarize the current literature on real-time continuous glucose monitors, focusing on devices that have been approved or are pending approval...
Duration of nocturnal hypoglycemia before seizuresBruce Buckingham
Lucile Packard Children s Hospital at Stanford, Pediatric Endocrinology, Stanford, California, USA
Diabetes Care 31:2110-2. 2008..Despite a high incidence of nocturnal hypoglycemia documented by the use of continuous glucose monitoring (CGM), there are no reports in the literature of nocturnal hypoglycemic seizures while a patient is wearing a CGM device...
Real-Time hypoglycemia prediction suite using continuous glucose monitoring: a safety net for the artificial pancreasEyal Dassau
Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, California, USA
Diabetes Care 33:1249-54. 2010..This approach can provide a solution to the problem of nocturnal hypoglycemia, a major concern of patients with diabetes...
Insulin pumps in young childrenKimberly Fuld
Division of Pediatric Endocrinology and Diabetes, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5208, USA
Diabetes Technol Ther 12:S67-71. 2010..There are advantages and disadvantages related to both CSII and MDI treatments, and ultimately the decision to use CSII should be individualized for each patient and family with the guidance of their diabetes team...
A randomized controlled trial of culturally tailored dance and reducing screen time to prevent weight gain in low-income African American girls: Stanford GEMSThomas N Robinson
Division of General Pediatrics and Stanford Prevention Research Center, Stanford University School of Medicine, 1070 Arastradero Road, Palo Alto, CA 94304, USA
Arch Pediatr Adolesc Med 164:995-1004. 2010..To test a 2-year community- and family-based obesity prevention program for low-income African American girls: Stanford GEMS (Girls' health Enrichment Multi-site Studies)...
Response to nocturnal alarms using a real-time glucose sensorBruce Buckingham
Stanford University School of Medicine, Stanford, California 94305 5208, USA
Diabetes Technol Ther 7:440-7. 2005..The objective of this study was to determine how subjects responded to alarms for hypo- and hyperglycemia while they were sleeping...
Serum luteinizing hormone rises within minutes after depot leuprolide injection: implications for monitoring therapySuruchi Bhatia
Department of Pediatrics, Division of Endocrinology and Diabetes, Stanford University, Stanford, California 94305 5208, USA
Pediatrics 109:E30. 2002..To find the time of the serum gonadotropin peak after depot leuprolide injection in children and to show that depot leuprolide therapy can be monitored by measuring serum luteinizing hormone (LH) immediately after injections...
Dance and reducing television viewing to prevent weight gain in African-American girls: the Stanford GEMS pilot studyThomas N Robinson
Division of General Pediatrics, Department of Pediatrics, The Stanford Center for Research in Disease Prevention, Palo Alto, CA 94304, USA
Ethn Dis 13:S65-77. 2003..To test the feasibility, acceptability, and potential efficacy of after-school dance classes and a family-based intervention to reduce television viewing, thereby reducing weight gain, among African-American girls...
Alternatives to growth hormone stimulation testing in childrenAngela Badaru
Division of Pediatric Endocrinology and Diabetes, Stanford University Medical Center, S 302, Stanford, CA 94305 5208, USA
Trends Endocrinol Metab 15:252-8. 2004..Here, we examine the alternatives to the GHST that are currently available and literature that supports their use. We believe that these alternative methods should replace the GHST...
Is growth hormone stimulation testing in children still appropriate?Laura M Gandrud
Division of Pediatric Endocrinology and Diabetes, Stanford University Medical Center, S 302, Stanford University, Stanford, CA 94305 5208, USA
Growth Horm IGF Res 14:185-94. 2004..We recommend that GH stimulation tests no longer routinely be used for the diagnosis of GHD in children...
Use of the Cygnus GlucoWatch biographer at a diabetes campLaura M Gandrud
Stanford University School of Medicine, Stanford, California 94305 5208, USA
Pediatrics 113:108-11. 2004..Detection and prevention of nocturnal hypoglycemia is a major medical concern at diabetes camps...
Catch-up growth in severe juvenile hypothyroidism: treatment with a GnRH analogLouisa Teng
Pediatric Endocrinology and Diabetes, Stanford Medical Center, Stanford, CA 94305-5208, USA
J Pediatr Endocrinol Metab 17:345-54. 2004..Changes in BMI Z score were similar for both groups. Our study suggests that the addition of GnRHa to LT4 may improve interval growth without imposing a risk of obesity in children with longstanding severe hypothyroidism...
Prorenin and vascular complications of diabetesJ A Luetscher
Department of Medicine, Stanford University School of Medicine, California
Am J Hypertens 2:382-6. 1989..In the majority of our patients with type 2 diabetes who are hypertensive or are taking a medication that affects plasma prorenin, microalbuminuria may prove to be a more reliable warning of vascular complications...
Bone mineral density in pediatric transplant recipientsMark W Daniels
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
Transplantation 76:673-8. 2003..Low bone density and the occurrence of vertebral fractures indicate that cardiac, renal, and bone marrow transplantation in children is associated with reduced bone health...
Glucose control in pediatric intensive care unit patients using an insulin-glucose algorithmKupper A Wintergerst
Pediatric Endocrinology, Kosair Children s Hospital, University of Louisville, Louisville, Kentucky 40202, USA
Diabetes Technol Ther 9:211-22. 2007..We have evaluated the use of a discrete proportional-integral-derivative (PID) algorithm to control hyperglycemia in pediatric ICU (PICU) patients both with and without diabetes...
Limitations of statistical measures of error in assessing the accuracy of continuous glucose sensorsCraig Kollman
The Jaeb Center for Health Research, Tampa, Florida 33647, USA
Diabetes Technol Ther 7:665-72; discussion 673-4. 2005..Various statistical methods are commonly used to assess the accuracy of near-continuous glucose sensors. The performance and reliability of these methods have not been well described...
JDRF randomized clinical trial to assess the efficacy of real-time continuous glucose monitoring in the management of type 1 diabetes: research design and methodsWilliam V Tamborlane
Diabetes Technol Ther 10:310-21. 2008..RESULTS: Recruitment for the study was completed on December 15, 2007. CONCLUSION: Results of this clinical trial should help establish whether or not current RT-CGM devices are beneficial to patients with T1D...
Early sexual maturation, body composition, and obesity in African-American girlsJohn H Himes
Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
Obes Res 12:64S-72S. 2004..To describe associations between sexual maturation and body composition in a sample of African-American girls who were participants in phase 1 pilot interventions of the Girls Health Enrichment Multisite Studies...
Continuous glucose monitoring and intensive treatment of type 1 diabetesWilliam V Tamborlane
N Engl J Med 359:1464-76. 2008..Further work is needed to identify barriers to effectiveness of continuous monitoring in children and adolescents. (ClinicalTrials.gov number, NCT00406133.)..
Initiation of insulin glargine in children and adolescents with type 1 diabetesChin Yao Tan
Faculty of Medicine, University of Melbourne, Parkville, Victoria, Australia
Pediatr Diabetes 5:80-6. 2004..CONCLUSION: This retrospective study suggests that glargine is at least as effective as other long-acting insulins but that care must be taken during the conversion process to avoid hypoglycemia...
Use of the DirecNet Applied Treatment Algorithm (DATA) for diabetes management with a real-time continuous glucose monitor (the FreeStyle Navigator)Bruce Buckingham
Pediatr Diabetes 9:142-7. 2008..CONCLUSIONS: These results show the feasibility of implementing the DATA when real-time continuous glucose monitoring is initiated and support its use in future clinical trials of real-time continuous glucose monitoring...
Relationship of A1C to glucose concentrations in children with type 1 diabetes: assessments by high-frequency glucose determinations by sensorsDarrell M Wilson
Diabetes Care 31:381-5. 2008..There is, however, substantial variability in individual mean glucose concentrations for a given A1C. Transforming reliable A1C values into calculated mean glucose values would, when applied to an individual, introduce substantial error...
Evaluation of factors affecting CGMS calibrationBruce A Buckingham
DirecNet Coordinating Center, Jaeb Center for Health Research, 15310 Amberly Drive, Suite 350, Tampa, FL 33647, USA
Diabetes Technol Ther 8:318-25. 2006..The optimal number/timing of calibrations entered into the CGMS (Medtronic MiniMed, Northridge, CA) continuous glucose monitoring system have not been previously described...
The accuracy of the FreeStyle Navigator continuous glucose monitoring system in children with type 1 diabetesDarrell M Wilson
DirecNet Coordinating Center, Jaeb Center for Health Research, 15310 Amberly Dr, Suite 350, Tampa, FL 33647, USA
Diabetes Care 30:59-64. 2007..To evaluate the accuracy and precision of the FreeStyle Navigator continuous glucose monitoring system in children with type 1 diabetes...
The accuracy of the Guardian RT continuous glucose monitor in children with type 1 diabetesMichael Tansey
Diabetes Technol Ther 10:266-72. 2008..The Guardian RT has an accuracy similar to that of other available continuous glucose monitors and can give important and useful clinical information...
Comparison of fingerstick hemoglobin A1c levels assayed by DCA 2000 with the DCCT/EDIC central laboratory assay: results of a Diabetes Research in Children Network (DirecNet) StudyWilliam V Tamborlane
Jaeb Center for Health Research, Tampa, FL 33647, USA
Pediatr Diabetes 6:13-6. 2005..The DCA 2000 + Analyzer (Bayer Inc., Tarrytown, NY, USA), which uses an immunoassay, is a very popular device for measuring HbA1c levels in pediatric diabetes practices...
Microvascular abnormalities in pediatric diabetic patientsAnthony T W Cheung
Department of Medical Pathology, University of California, Davis School of Medicine, 95616, USA
Microvasc Res 63:252-8. 2002..This study confirms that CAIM may represent the availability of a useful real-time technology to study conjunctival microvascular abnormalities in vascular diseases in juvenile as well as adult patients...
Research Grants
- Type 1 Diabetes TrialNet at StanfordDarrell Wilson; Fiscal Year: 2007..We propose to initiate Phase 1 safety studies followed by Phase 2 efficacy studies using DNA vaccination with insulin B:9-23. ..
