Cornelia Weyand

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis
    Lan Shao
    Department of Medicine, Immunology and Rheumatology, Stanford University, Stanford, CA, USA
    EMBO Mol Med 2:415-27. 2010
  2. pmc Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
    Zhen Yang
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305
    J Exp Med 210:2119-34. 2013
  3. ncbi request reprint The immunopathology of giant cell arteritis: diagnostic and therapeutic implications
    Cornelia M Weyand
    Department of Medicine, and the Byers Eye Institute at Stanford, Stanford University, Stanford, CA, USA
    J Neuroophthalmol 32:259-65. 2012
  4. pmc IFN-γ and IL-17: the two faces of T-cell pathology in giant cell arteritis
    Cornelia M Weyand
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305 5166, USA
    Curr Opin Rheumatol 23:43-9. 2011
  5. pmc Giant cell arteritis: immune and vascular aging as disease risk factors
    Shalini V Mohan
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305 5166, USA
    Arthritis Res Ther 13:231. 2011
  6. pmc Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis
    Kisha Piggott
    Lowance Center for Human Immunology and Rheumatology, Emory University, Atlanta, GA, USA
    Circulation 123:309-18. 2011
  7. pmc Th17 and Th1 T-cell responses in giant cell arteritis
    Jiusheng Deng
    Division of Immunology and Rheumatology, Stanford University School of Medicine, 269 W Campus Dr, Stanford, CA 94305, USA
    Circulation 121:906-15. 2010

Research Grants

  1. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2005
  2. CD8 T Cells in Rheumatoid Arthritis
    Cornelia Weyand; Fiscal Year: 2007
  3. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2009
  4. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia M Weyand; Fiscal Year: 2010
  5. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2002
  6. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2001
  7. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2004
  8. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2005
  9. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2000
  10. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2003

Collaborators

  • Jorg J Goronzy
  • Shalini V Mohan
  • Jiusheng Deng
  • Zhen Yang
  • Kisha Piggott
  • Lan Shao
  • Hiroshi Fujii
  • Kenneth Warrington
  • Jonathan W Kim
  • Jessica T Kubo
  • Manisha Desai
  • Y Joyce Liao
  • Brian Younge
  • Richard A Olshen
  • Brian R Younge

Detail Information

Publications7

  1. pmc DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis
    Lan Shao
    Department of Medicine, Immunology and Rheumatology, Stanford University, Stanford, CA, USA
    EMBO Mol Med 2:415-27. 2010
    ..Therapeutic blockade of the DNA-PK-dependent cell-death machinery may rejuvenate the immune system in RA...
  2. pmc Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
    Zhen Yang
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305
    J Exp Med 210:2119-34. 2013
    ....
  3. ncbi request reprint The immunopathology of giant cell arteritis: diagnostic and therapeutic implications
    Cornelia M Weyand
    Department of Medicine, and the Byers Eye Institute at Stanford, Stanford University, Stanford, CA, USA
    J Neuroophthalmol 32:259-65. 2012
    ..Expansion of the therapeutic armamentarium for GCA needs to focus on approaches that mitigate the impact of the aging artery and adapt to the needs of the immunosenescent host...
  4. pmc IFN-γ and IL-17: the two faces of T-cell pathology in giant cell arteritis
    Cornelia M Weyand
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305 5166, USA
    Curr Opin Rheumatol 23:43-9. 2011
    ..Recent data demonstrate that at least two separate lineages of CD4 T cells participate in vascular inflammation, providing an important clue that multiple disease instigators may initiate pathogenic immunity...
  5. pmc Giant cell arteritis: immune and vascular aging as disease risk factors
    Shalini V Mohan
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305 5166, USA
    Arthritis Res Ther 13:231. 2011
    ..Thus, the aging process impacts the two major biologic systems that liaise to promote giant cell arteritis; the immune system and the vessel wall niche...
  6. pmc Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis
    Kisha Piggott
    Lowance Center for Human Immunology and Rheumatology, Emory University, Atlanta, GA, USA
    Circulation 123:309-18. 2011
    ....
  7. pmc Th17 and Th1 T-cell responses in giant cell arteritis
    Jiusheng Deng
    Division of Immunology and Rheumatology, Stanford University School of Medicine, 269 W Campus Dr, Stanford, CA 94305, USA
    Circulation 121:906-15. 2010
    ..The effects of glucocorticoids on the systemic and vascular components of GCA are not understood...

Research Grants49

  1. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2005
    ..These experiments will help us understand the immunobiology of healthy and inflamed arteries, advance our understanding of the events initiating vasculitis, and may provide new avenues for therapeutic intervention. ..
  2. CD8 T Cells in Rheumatoid Arthritis
    Cornelia Weyand; Fiscal Year: 2007
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  3. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2009
    ..Receptor-ligand pairs utilized by inflammatory cells are examined with the hope that disruption of dendritic cell-lymphocyte interactions can be exploited for novel therapeutic strategies of this vision-threatening disease. ..
  4. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia M Weyand; Fiscal Year: 2010
    ..Receptor-ligand pairs utilized by inflammatory cells are examined with the hope that disruption of dendritic cell-lymphocyte interactions can be exploited for novel therapeutic strategies of this vision-threatening disease. ..
  5. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2002
    ..These experiments will help us understand the immunobiology of healthy and inflamed arteries, advance our understanding of the events initiating vasculitis, and may provide new avenues for therapeutic intervention. ..
  6. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2001
    ..We anticipate that these studies will lead to increased understanding of the function and the anti-inflammatory potency of synovial CD8 T cells and the development of novel therapeutic approaches for patients with RA. ..
  7. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2004
    ..These experiments will help us understand the immunobiology of healthy and inflamed arteries, advance our understanding of the events initiating vasculitis, and may provide new avenues for therapeutic intervention. ..
  8. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2005
    ..abstract_text> ..
  9. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2000
    ..We anticipate that these studies will lead to increased understanding of the function and the anti-inflammatory potency of synovial CD8 T cells and the development of novel therapeutic approaches for patients with RA. ..
  10. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2003
    ..We anticipate that these studies will lead to increased understanding of the function and the anti-inflammatory potency of synovial CD8 T cells and the development of novel therapeutic approaches for patients with RA. ..
  11. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2003
    ..abstract_text> ..
  12. CD8 T Cells in Rheumatoid Arthritis
    Cornelia Weyand; Fiscal Year: 2006
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  13. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2004
    ..abstract_text> ..
  14. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2002
    ..We anticipate that these studies will lead to increased understanding of the function and the anti-inflammatory potency of synovial CD8 T cells and the development of novel therapeutic approaches for patients with RA. ..
  15. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2003
    ..abstract_text> ..
  16. OLIGOCLONAL T CELL EXPANSION AND RHEUMATOID ARTHRITIS
    Cornelia M Weyand; Fiscal Year: 2010
    ..The studies will include vaccinating RA patients with an influenza vaccine to test whether they can build sufficient T cells to be protected from infection. ..
  17. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2003
    ..These experiments will help us understand the immunobiology of healthy and inflamed arteries, advance our understanding of the events initiating vasculitis, and may provide new avenues for therapeutic intervention. ..
  18. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2001
    ..abstract_text> ..
  19. CD8 T Cells in Rheumatoid Arthritis
    Cornelia Weyand; Fiscal Year: 2009
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  20. OLIGOCLONAL T CELL EXPANSION AND RHEUMATOID ARTHRITIS
    Cornelia M Weyand; Fiscal Year: 2009
    ..The studies will include vaccinating RA patients with an influenza vaccine to test whether they can build sufficient T cells to be protected from infection. ..
  21. CD8 T Cells in Rheumatoid Arthritis
    Cornelia M Weyand; Fiscal Year: 2009
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  22. CD8 T Cells in Rheumatoid Arthritis
    Cornelia M Weyand; Fiscal Year: 2010
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  23. OLIGOCLONAL T CELL EXPANSION AND RHEUMATOID ARTHRITIS
    Cornelia Weyand; Fiscal Year: 2009
    ..The studies will include vaccinating RA patients with an influenza vaccine to test whether they can build sufficient T cells to be protected from infection. ..
  24. CD8 T Cells in Rheumatoid Arthritis
    Cornelia M Weyand; Fiscal Year: 2010
    ..The goal of this proposal is to understand how such anti-inflammatory lymphocytes function and how they can be harnessed as novel therapeutic reagents in RA. ..
  25. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2003
    ..These experiments will help us understand the immunobiology of healthy and inflamed arteries, advance our understanding of the events initiating vasculitis, and may provide new avenues for therapeutic intervention. ..
  26. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 1999
    ..Pathways involved in causing ischemic disease with subsequent blindness should represent premier targets for new therapeutic strategies in GCA. ..
  27. OLIGOCLONAL T-CELL EXPANSION AND RHEUMATOID ARTHRITIS
    Cornelia Weyand; Fiscal Year: 1993
    ....
  28. OLIGOCLONAL T CELL EXPANSION AND RHEUMATOID ARTHRITIS
    Cornelia Weyand; Fiscal Year: 1999
    ....
  29. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2000
    ..Pathways involved in causing ischemic disease with subsequent blindness should represent premier targets for new therapeutic strategies in GCA. ..
  30. OCULAR DISEASE IN GIANT CELL ARTERITIS
    Cornelia Weyand; Fiscal Year: 2001
    ..Pathways involved in causing ischemic disease with subsequent blindness should represent premier targets for new therapeutic strategies in GCA. ..
  31. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2002
    ..abstract_text> ..
  32. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 1999
    ..We anticipate that these studies will lead to increased understanding of the function and the anti-inflammatory potency of synovial CD8 T cells and the development of novel therapeutic approaches for patients with RA. ..
  33. IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMES
    Cornelia Weyand; Fiscal Year: 2003
    ..abstract_text> ..
  34. CD8 T CELLS IN RHEUMATOID SYNOVITIS
    Cornelia Weyand; Fiscal Year: 2003
    ..We anticipate that these studies will lead to increased understanding of the function and the anti-inflammatory potency of synovial CD8 T cells and the development of novel therapeutic approaches for patients with RA. ..