Irene Wapnir

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections
    Irene L Wapnir
    Department of Surgery, Stanford University School of Medicine, Stanford, California 94305 5655, USA
    J Clin Endocrinol Metab 88:1880-8. 2003
  2. doi request reprint Intraoperative imaging of nipple perfusion patterns and ischemic complications in nipple-sparing mastectomies
    Irene Wapnir
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Ann Surg Oncol 21:100-6. 2014
  3. pmc New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
    Holbrook E Kohrt
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    BMC Cancer 8:66. 2008
  4. pmc Expression of the Na+/I- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus
    Aron Altorjay
    Department of Surgery, St George University Teaching Hospital H 8000 Székesfehérvár, Hungary
    BMC Cancer 7:5. 2007
  5. pmc Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS
    Irene L Wapnir
    Department of Surgery 300 Pasteur Dr H3625, Stanford University School of Medicine, Stanford, CA 94305 5655
    J Natl Cancer Inst 103:478-88. 2011
  6. pmc Leiomyosarcoma of the breast in a patient with a 10-year-history of cyclophosphamide exposure: a case report
    Jennifer De la Pena
    300 Pasteur Dr, H3625 Stanford, CA 94305, USA
    Cases J 1:301. 2008
  7. pmc Progress on BIG 1-02/IBCSG 27-02/NSABP B-37, a prospective randomized trial evaluating chemotherapy after local therapy for isolated locoregional recurrences of breast cancer
    Irene L Wapnir
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistics Center, Pittsburgh, PA, USA
    Ann Surg Oncol 15:3227-31. 2008
  8. doi request reprint A randomized clinical trial of adjuvant chemotherapy for radically resected locoregional relapse of breast cancer: IBCSG 27-02, BIG 1-02, and NSABP B-37
    Irene L Wapnir
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, PA, USA
    Clin Breast Cancer 8:287-92. 2008
  9. ncbi request reprint The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid
    Irene L Wapnir
    Department of Surgery, Stanford University School of Medicine, Stanford, California, USA
    Clin Cancer Res 10:4294-302. 2004
  10. ncbi request reprint Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in five National Surgical Adjuvant Breast and Bowel Project node-positive adjuvant breast cancer trials
    Irene L Wapnir
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, PA, USA
    J Clin Oncol 24:2028-37. 2006

Detail Information

Publications20

  1. ncbi request reprint Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections
    Irene L Wapnir
    Department of Surgery, Stanford University School of Medicine, Stanford, California 94305 5655, USA
    J Clin Endocrinol Metab 88:1880-8. 2003
    ..Elucidating the regulatory mechanisms that render NIS functional in extrathyroidal carcinomas may make (131)I therapy feasible...
  2. doi request reprint Intraoperative imaging of nipple perfusion patterns and ischemic complications in nipple-sparing mastectomies
    Irene Wapnir
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Ann Surg Oncol 21:100-6. 2014
    ..The blood flow pattern to the breast skin and the NAC were evaluated and a classification scheme was developed...
  3. pmc New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
    Holbrook E Kohrt
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    BMC Cancer 8:66. 2008
    ..Our goal was to develop new models to quantify the risk of NSLN metastasis in SLN-positive patients and to compare predictive capabilities to another widely used model...
  4. pmc Expression of the Na+/I- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus
    Aron Altorjay
    Department of Surgery, St George University Teaching Hospital H 8000 Székesfehérvár, Hungary
    BMC Cancer 7:5. 2007
    ..Whereas NIS expression and regulation have been extensively investigated in healthy and neoplastic thyroid and breast tissues, little is known about NIS expression and function along the healthy and diseased gastrointestinal tract...
  5. pmc Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS
    Irene L Wapnir
    Department of Surgery 300 Pasteur Dr H3625, Stanford University School of Medicine, Stanford, CA 94305 5655
    J Natl Cancer Inst 103:478-88. 2011
    ..We evaluated invasive IBTR (I-IBTR) and its influence on survival among participants in two National Surgical Adjuvant Breast and Bowel Project (NSABP) randomized trials for DCIS...
  6. pmc Leiomyosarcoma of the breast in a patient with a 10-year-history of cyclophosphamide exposure: a case report
    Jennifer De la Pena
    300 Pasteur Dr, H3625 Stanford, CA 94305, USA
    Cases J 1:301. 2008
    ..Ultrasound guided core biopsy revealed a spindle cell neoplasm characterized on final pathology as a low grade leiomyosarcoma...
  7. pmc Progress on BIG 1-02/IBCSG 27-02/NSABP B-37, a prospective randomized trial evaluating chemotherapy after local therapy for isolated locoregional recurrences of breast cancer
    Irene L Wapnir
    National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistics Center, Pittsburgh, PA, USA
    Ann Surg Oncol 15:3227-31. 2008
    ....
  8. doi request reprint A randomized clinical trial of adjuvant chemotherapy for radically resected locoregional relapse of breast cancer: IBCSG 27-02, BIG 1-02, and NSABP B-37
    Irene L Wapnir
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, PA, USA
    Clin Breast Cancer 8:287-92. 2008
    ..Although multidrug regimens are preferred, the agents, doses, and use of supportive therapy are at the discretion of the investigator...
  9. ncbi request reprint The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid
    Irene L Wapnir
    Department of Surgery, Stanford University School of Medicine, Stanford, California, USA
    Clin Cancer Res 10:4294-302. 2004
    ..Breast cancer is the only other cancer demonstrating endogenous functional NIS expression. Until now, NIS activity in breast cancer metastases (BCM) was unproven...
  10. ncbi request reprint Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in five National Surgical Adjuvant Breast and Bowel Project node-positive adjuvant breast cancer trials
    Irene L Wapnir
    National Surgical Adjuvant Breast and Bowel Project Operations Office and Biostatistical Center, Pittsburgh, PA, USA
    J Clin Oncol 24:2028-37. 2006
    ..Locoregional failure after breast-conserving surgery is associated with increased risk of distant disease and death. The magnitude of this risk in patients receiving chemotherapy has not been adequately characterized...
  11. pmc Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in patients treated by breast-conserving therapy in five National Surgical Adjuvant Breast and Bowel Project protocols of node-negative breast cancer
    Stewart J Anderson
    Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    J Clin Oncol 27:2466-73. 2009
    ..Locoregional failure (LRF) after breast-conserving therapy (BCT) is associated with increased risk of distant disease and death. The magnitude of this risk has not been adequately characterized in patients with lymph node-negative disease...
  12. doi request reprint Breast cancer brain metastases express the sodium iodide symporter
    Corinne Renier
    Department of Surgery, Stanford University School of Medicine, 300 Pasteur Drive H 3625, Stanford, CA 94305 5655, USA
    J Neurooncol 96:331-6. 2010
    ..Altogether, these findings indicate that NIS expression is prevalent in breast cancer brain metastases and could have a therapeutic role via the delivery of radioactive iodide and selective ablation of tumor cells...
  13. doi request reprint Endogenous NIS expression in triple-negative breast cancers
    Corinne Renier
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Ann Surg Oncol 16:962-8. 2009
    ..Treatment of triple-negative breast cancers [estrogen/progesterone receptor-negative and HER2-negative (ER-/PR-/HER2-)] is primarily limited to chemotherapy. Our aim was to characterize NIS expression in this subset of tumors...
  14. doi request reprint Timing of breast cancer treatments with oocyte retrieval and embryo cryopreservation
    Jennifer Baynosa
    Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Am Coll Surg 209:603-7. 2009
    ..In this study, we compared timing of chemotherapy in women who underwent ovarian stimulation/oocyte retrieval (OR) and embryo cryopreservation with those who did not...
  15. ncbi request reprint Bioluminescent monitoring of NIS-mediated (131)I ablative effects in MCF-7 xenografts
    Malavika Ghosh
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Mol Imaging 5:76-84. 2006
    ..In summary, a pattern of tumor regression occurring over the first three weeks after (131)I administration was observed in NIS-expressing breast cancer xenografts...
  16. doi request reprint Ex vivo Evans blue assessment of the blood brain barrier in three breast cancer brain metastasis models
    John Do
    Department of Surgery, Stanford University School of Medicine, Stanford, CA, 94305, USA
    Breast Cancer Res Treat 144:93-101. 2014
    ..EB assessment of the integrity of the BBB provides useful information relevant to drug testing in preclinical BCBM models...
  17. doi request reprint The diagnostic value of nipple discharge cytology: breast imaging complements predictive value of nipple discharge cytology
    Ogori N Kalu
    Department of Surgery, Stanford University Medical Center, Stanford, California, USA
    J Surg Oncol 106:381-5. 2012
    ..Papilloma is the most common finding associated with pathologic nipple discharge. In the absence of breast imaging abnormalities, the incidence of occult malignancy is <3%...
  18. doi request reprint Metastases to the breast: alveolar soft part sarcoma in adolescents
    Andrea Madrigrano
    Department of General Surgery, Stanford University and Medical Center, CA 94305 5655, USA
    Clin Breast Cancer 8:92-3. 2008
    ..Metastases to the breast comprise 0.5%-2% of breast neoplasms. This is a case report of an 18-year-old woman with an alveolar soft part sarcoma metastatic to the breast...
  19. ncbi request reprint Resolution of hypoalbuminemia after excision of malignant phyllodes tumor
    Laila Samiian
    Department of Surgery, Stanford University School of Medicine, CA 94305 5655, USA
    Clin Breast Cancer 7:411-2. 2006
    ..Final pathology revealed a 22-cm malignant phyllodes tumor. Hypoalbuminemia and alkaline phosphatase quickly resolved after surgical excision without any further treatment...
  20. ncbi request reprint Egg retrieval with cryopreservation does not delay breast cancer treatment
    Andrea Madrigrano
    Department of Surgery, Stanford University Medical Center, 300 Pasteur Dr, RM H3625, Stanford, CA 94305 5655, USA
    Am J Surg 194:477-81. 2007
    ..Infertility is a concern to young women diagnosed with breast cancer. Advances in fertility technology have made it possible to bank fertilized embryos...