Zhi Yong Wang

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Circadian rhythms of ethylene emission in Arabidopsis
    Simon C Thain
    Unit Plant Hormone Signaling and Bio Imaging, Department of Molecular Genetics, University of Ghent, Belgium
    Plant Physiol 136:3751-61. 2004
  2. pmc The brassinosteroid signal transduction pathway
    Zhi Yong Wang
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Cell Res 16:427-34. 2006
  3. ncbi request reprint Brassinosteroid signal transduction--choices of signals and receptors
    Zhi Yong Wang
    Department of Plant Biology, Carnegie Institution, 260 Panama Street, Stanford, CA 94305, USA
    Trends Plant Sci 9:91-6. 2004
  4. pmc Integration of brassinosteroid signal transduction with the transcription network for plant growth regulation in Arabidopsis
    Yu Sun
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Dev Cell 19:765-77. 2010
  5. pmc BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses
    Jun Xian He
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Science 307:1634-8. 2005
  6. pmc An essential role for 14-3-3 proteins in brassinosteroid signal transduction in Arabidopsis
    Srinivas S Gampala
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Dev Cell 13:177-89. 2007
  7. pmc Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors
    Tae Wuk Kim
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Nat Cell Biol 11:1254-60. 2009
  8. pmc The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis
    Jun Xian He
    Department of Plant Biology, Carnegie Institution of Washington, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:10185-90. 2002
  9. pmc Interaction between BZR1 and PIF4 integrates brassinosteroid and environmental responses
    Eunkyoo Oh
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Nat Cell Biol 14:802-9. 2012
  10. doi request reprint Brassinosteroid signaling network and regulation of photomorphogenesis
    Zhi Yong Wang
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Annu Rev Genet 46:701-24. 2012

Collaborators

Detail Information

Publications32

  1. pmc Circadian rhythms of ethylene emission in Arabidopsis
    Simon C Thain
    Unit Plant Hormone Signaling and Bio Imaging, Department of Molecular Genetics, University of Ghent, Belgium
    Plant Physiol 136:3751-61. 2004
    ..Mutants with altered ethylene production or signaling also retained normal rhythmicity of leaf movement. We conclude that circadian rhythms of ethylene production are not critical for rhythmic growth...
  2. pmc The brassinosteroid signal transduction pathway
    Zhi Yong Wang
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Cell Res 16:427-34. 2006
    ..The BR signaling pathway has become a paradigm for both receptor kinase signaling in plants and steroid signaling by cell surface receptors in general...
  3. ncbi request reprint Brassinosteroid signal transduction--choices of signals and receptors
    Zhi Yong Wang
    Department of Plant Biology, Carnegie Institution, 260 Panama Street, Stanford, CA 94305, USA
    Trends Plant Sci 9:91-6. 2004
    ..Recent studies demonstrated that tomato BRI1 (tBRI1) perceives both BR and the peptide hormone systemin, raising new questions about the molecular mechanism and evolution of receptor-ligand specificity...
  4. pmc Integration of brassinosteroid signal transduction with the transcription network for plant growth regulation in Arabidopsis
    Yu Sun
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Dev Cell 19:765-77. 2010
    ..Our results provide a genomic map of steroid hormone actions in plants that reveals a regulatory network that integrates hormonal and light-signaling pathways for plant growth regulation...
  5. pmc BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses
    Jun Xian He
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Science 307:1634-8. 2005
    ....
  6. pmc An essential role for 14-3-3 proteins in brassinosteroid signal transduction in Arabidopsis
    Srinivas S Gampala
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Dev Cell 13:177-89. 2007
    ..This study demonstrates that multiple mechanisms are required for BR regulation of gene expression and plant growth...
  7. pmc Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors
    Tae Wuk Kim
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Nat Cell Biol 11:1254-60. 2009
    ..This study establishes a fully connected BR signalling pathway and provides new insights into the mechanism of GSK3 regulation...
  8. pmc The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis
    Jun Xian He
    Department of Plant Biology, Carnegie Institution of Washington, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 99:10185-90. 2002
    ..These results strongly suggest that BIN2 phosphorylates BZR1 and targets it for degradation and that BR signaling causes BZR1 dephosphorylation and accumulation by inhibiting BIN2 activity...
  9. pmc Interaction between BZR1 and PIF4 integrates brassinosteroid and environmental responses
    Eunkyoo Oh
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Nat Cell Biol 14:802-9. 2012
    ..These results show that the BZR1-PIF4 interaction controls a core transcription network, enabling plant growth co-regulation by the steroid and environmental signals...
  10. doi request reprint Brassinosteroid signaling network and regulation of photomorphogenesis
    Zhi Yong Wang
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Annu Rev Genet 46:701-24. 2012
    ..The molecular connections in the BR signaling network demonstrate a robust steroid signaling system that has evolved in plants to orchestrate signal transduction, genome expression, metabolism, defense, and development...
  11. pmc A proteomics study of brassinosteroid response in Arabidopsis
    Zhiping Deng
    Department of Plant Biology, Carnegie Institution of Washington, Stanford, California 94305, USA
    Mol Cell Proteomics 6:2058-71. 2007
    ..This study provides novel insights into the molecular networks that link BR signaling to specific cellular and physiological responses...
  12. doi request reprint Genome-wide identification of transcription factor-binding sites in plants using chromatin immunoprecipitation followed by microarray (ChIP-chip) or sequencing (ChIP-seq)
    Jia Ying Zhu
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA, USA
    Methods Mol Biol 876:173-88. 2012
    ..We have used these protocols to successfully identify direct target genes of the BZR1 TF of the brassinosteroid signaling pathway in both Arabidopsis and rice...
  13. pmc Proteomics studies of brassinosteroid signal transduction using prefractionation and two-dimensional DIGE
    Wenqiang Tang
    Department of Plant Biology, Carnegie Institution of Washington, Stanford, California 94305, USA
    Mol Cell Proteomics 7:728-38. 2008
    ..Our study demonstrates that prefractionation coupled with 2-D DIGE is a powerful approach for studying signal transduction...
  14. pmc Brassinosteroids regulate organ boundary formation in the shoot apical meristem of Arabidopsis
    Joshua M Gendron
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:21152-7. 2012
    ..Activation of BR signaling represses CUC gene expression and causes organ fusion phenotypes. This study uncovers a role for BR in the spatiotemporal control of organ boundary formation and morphogenesis in the SAM...
  15. pmc Brassinosteroid regulates stomatal development by GSK3-mediated inhibition of a MAPK pathway
    Tae Wuk Kim
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305 4150, USA
    Nature 482:419-22. 2012
    ....
  16. pmc Chemical genetic dissection of brassinosteroid-ethylene interaction
    Joshua M Gendron
    Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
    Mol Plant 1:368-79. 2008
    ..The BRP-related compounds can be useful tools for manipulating plant growth and studying hormone interactions...
  17. pmc The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2
    Tae Wuk Kim
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Mol Cell 43:561-71. 2011
    ..This study thus demonstrates a complete phosphorylation/dephosphorylation cascade linking a steroid-activated receptor kinase to a GSK3-like kinase in plants...
  18. pmc Brassinosteroid, gibberellin and phytochrome impinge on a common transcription module in Arabidopsis
    Ming Yi Bai
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Nat Cell Biol 14:810-7. 2012
    ..The results demonstrate that GA releases DELLA-mediated inhibition of BZR1, and that the DELLA-BZR1-PIF4 interaction defines a core transcription module that mediates coordinated growth regulation by GA, BR and light signals...
  19. pmc A triple helix-loop-helix/basic helix-loop-helix cascade controls cell elongation downstream of multiple hormonal and environmental signaling pathways in Arabidopsis
    Ming Yi Bai
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Plant Cell 24:4917-29. 2012
    ..Our study demonstrates that PREs, IBH1, and HBI1 form a chain of antagonistic switches that regulates cell elongation downstream of multiple external and endogenous signals...
  20. pmc Brassinosteroid signalling
    Jia Ying Zhu
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA
    Development 140:1615-20. 2013
    ..Here, we provide an overview of the highly integrated BR signalling network and explain how this steroid hormone functions as a master regulator of plant growth, development and metabolism...
  21. doi request reprint Brassinosteroid signal transduction from receptor kinases to transcription factors
    Tae Wuk Kim
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    Annu Rev Plant Biol 61:681-704. 2010
    ..Thus, the BR signaling pathway provides a paradigm for understanding receptor kinase-mediated signal transduction as well as tools for the genetic improvement of the productivity of crop plants...
  22. pmc Prefoldin 6 is required for normal microtubule dynamics and organization in Arabidopsis
    Ying Gu
    Department of Plant Biology, Carnegie Institution for Science, 260 Panama Street, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 105:18064-9. 2008
    ..These results support the concept that the function of microtubules is critically dependent on the absolute amount of tubulins...
  23. pmc Multiple mechanisms modulate brassinosteroid signaling
    Joshua M Gendron
    Department of Plant Biology, Carnegie Institution, 260 Panama Street, Stanford, CA 94305, USA
    Curr Opin Plant Biol 10:436-41. 2007
    ..In addition, BRI1 signaling from the endosomes and BR-independent functions of BAK1 have been observed. However, a major gap still exists in the current BR signaling pathway between the receptor complex and downstream signaling events...
  24. doi request reprint Quantitative analysis of protein phosphorylation using two-dimensional difference gel electrophoresis
    Zhiping Deng
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA, USA
    Methods Mol Biol 876:47-66. 2012
    ..For IP-DIGE, proteins of interest can be immunopurified and then analyzed by 2-D DIGE to confirm changes of posttranslational modifications that alter the charge or size of the proteins...
  25. pmc Identification of O-linked β-D-N-acetylglucosamine-modified proteins from Arabidopsis
    Shou Ling Xu
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA, USA
    Methods Mol Biol 876:33-45. 2012
    ..Here we describe the use of lectin affinity chromatography combined with electron transfer dissociation mass spectrometry to enrich and to detect O-GlcNAc modified peptides from Arabidopsis...
  26. ncbi request reprint TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1
    Eunkyoo Oh
    1 Department of Plant Biology, Carnegie Institution for Science, 260 Panama Street, Stanford, California 94305, USA 2
    Nat Commun 5:4140. 2014
    ..BR repression of gene expression also requires histone deacetylases that interact with TPL. Our study demonstrates key roles of the EAR motif and TPL in BR regulation of gene expression and plant growth. ..
  27. pmc The bHLH transcription factor HBI1 mediates the trade-off between growth and pathogen-associated molecular pattern-triggered immunity in Arabidopsis
    Min Fan
    Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305
    Plant Cell 26:828-41. 2014
    ..These results show that HBI1, as a component of the central growth regulation circuit, functions as a major node of crosstalk that mediates a trade-off between growth and immunity in plants...
  28. pmc BSKs mediate signal transduction from the receptor kinase BRI1 in Arabidopsis
    Wenqiang Tang
    Department of Plant Biology, Carnegie Institution of Washington, Stanford, CA 94305, USA
    Science 321:557-60. 2008
    ..These results demonstrate that BSKs are the substrates of BRI1 kinase that activate downstream BR signal transduction...
  29. pmc Brassinosteroid action in flowering plants: a Darwinian perspective
    Ulrich Kutschera
    Department of Plant Biology, Carnegie Institution for Science, Stanford, California 94305, USA
    J Exp Bot 63:3511-22. 2012
    ....
  30. pmc Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice
    Ming Yi Bai
    Key Laboratory of Photosynthesis and Environmental Molecular Biology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
    Proc Natl Acad Sci U S A 104:13839-44. 2007
    ..These results demonstrate a conserved function of OsBZR1 and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice...
  31. ncbi request reprint Constitutive expression of CIR1 (RVE2) affects several circadian-regulated processes and seed germination in Arabidopsis
    Xiangbo Zhang
    National Laboratory for Protein Engineering and Plant Genetic Engineering, Peking Yale Joint Research Center for Plant Molecular Genetics and AgroBiotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Plant J 51:512-25. 2007
    ..These results suggest that CIR1 is possibly part of a regulatory feedback loop that controls a subset of the circadian outputs and modulates the central oscillator...
  32. pmc Circadian rhythms confer a higher level of fitness to Arabidopsis plants
    Rachel M Green
    Department of Molecular, Cell and Developmental Biology, P O Box 160606, University of California Los Angeles, Los Angeles, CA 90095 1606, USA
    Plant Physiol 129:576-84. 2002
    ..In addition, we demonstrate that two other circadian rhythm mutants, LHY-ox and elf3, have low-viability phenotypes. Our findings demonstrate the adaptive advantage of circadian rhythms in Arabidopsis...