Clarissa L Waites

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Mechanisms of vertebrate synaptogenesis
    Clarissa L Waites
    Department of Psychiatry and Behavioral Science, Nancy Pritzker Laboratory, Stanford University, Palo Alto, CA 94304 5485, USA
    Annu Rev Neurosci 28:251-74. 2005
  2. pmc Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation
    Clarissa L Waites
    1 Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA 2 Departments of Pathology and Cell Biology and Neuroscience, Columbia University Medical Center, New York, NY, USA
    EMBO J 32:954-69. 2013
  3. pmc Synaptic SAP97 isoforms regulate AMPA receptor dynamics and access to presynaptic glutamate
    Clarissa L Waites
    Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, 1201 Welch Road, Palo Alto, CA 94304 5485, USA
    J Neurosci 29:4332-45. 2009
  4. pmc SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway
    Okunola Jeyifous
    Department of Psychiatry and Behavioral Science, Stanford University, Palo Alto, California, USA
    Nat Neurosci 12:1011-9. 2009
  5. pmc Piccolo regulates the dynamic assembly of presynaptic F-actin
    Clarissa L Waites
    Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, California 94304 5485, USA
    J Neurosci 31:14250-63. 2011
  6. ncbi request reprint Synapse development: still looking for the forest, still lost in the trees
    Craig C Garner
    Department of Psychiatry and Behavioral Science, Nancy Pritzer Laboratory, Stanford University, Palo Alto, CA 94304 5485, USA
    Cell Tissue Res 326:249-62. 2006
  7. pmc Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis
    Sergio Leal-Ortiz
    Deptartment of Psychiatry and Behavioral Science, Nancy Pritzker Laboratory, Stanford University, Palo Alto, CA 94304, USA
    J Cell Biol 181:831-46. 2008
  8. doi request reprint Presynaptic function in health and disease
    Clarissa L Waites
    Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University School of Medicine, 1201 Welch Rd Palo Alto, CA 94304 5485, USA
    Trends Neurosci 34:326-37. 2011
  9. ncbi request reprint Transsynaptic signaling by postsynaptic synapse-associated protein 97
    Maria Paz Regalado
    Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, Palo Alto, California 94304 5485, USA
    J Neurosci 26:2343-57. 2006
  10. ncbi request reprint Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines
    Haiyan Li
    Graduate Programs in Neuroscience and Cell Biology, Department of Neurology and Physiology, UCSF School of Medicine, 600 16th Street, San Francisco, California 94143, USA
    Neuron 48:619-33. 2005

Research Grants

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Mechanisms of vertebrate synaptogenesis
    Clarissa L Waites
    Department of Psychiatry and Behavioral Science, Nancy Pritzker Laboratory, Stanford University, Palo Alto, CA 94304 5485, USA
    Annu Rev Neurosci 28:251-74. 2005
    ..Although synapse formation and elimination are hallmarks of early development, these processes are also fundamental to learning, memory, and cognition in the mature brain...
  2. pmc Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation
    Clarissa L Waites
    1 Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA 2 Departments of Pathology and Cell Biology and Neuroscience, Columbia University Medical Center, New York, NY, USA
    EMBO J 32:954-69. 2013
    ..Our findings demonstrate a novel role for Bassoon and Piccolo as critical regulators of presynaptic ubiquitination and proteostasis...
  3. pmc Synaptic SAP97 isoforms regulate AMPA receptor dynamics and access to presynaptic glutamate
    Clarissa L Waites
    Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, 1201 Welch Road, Palo Alto, CA 94304 5485, USA
    J Neurosci 29:4332-45. 2009
    ..These results indicate that N-terminal splicing of SAP97 can control synaptic strength by regulating the distribution of AMPARs and, hence, their responsiveness to presynaptically released glutamate...
  4. pmc SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway
    Okunola Jeyifous
    Department of Psychiatry and Behavioral Science, Stanford University, Palo Alto, California, USA
    Nat Neurosci 12:1011-9. 2009
    ..These findings indicate that NMDARs are sorted away from AMPARs via a non-conventional secretory pathway that utilizes dendritic Golgi outposts...
  5. pmc Piccolo regulates the dynamic assembly of presynaptic F-actin
    Clarissa L Waites
    Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, California 94304 5485, USA
    J Neurosci 31:14250-63. 2011
    ....
  6. ncbi request reprint Synapse development: still looking for the forest, still lost in the trees
    Craig C Garner
    Department of Psychiatry and Behavioral Science, Nancy Pritzer Laboratory, Stanford University, Palo Alto, CA 94304 5485, USA
    Cell Tissue Res 326:249-62. 2006
    ....
  7. pmc Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis
    Sergio Leal-Ortiz
    Deptartment of Psychiatry and Behavioral Science, Nancy Pritzker Laboratory, Stanford University, Palo Alto, CA 94304, USA
    J Cell Biol 181:831-46. 2008
    ..This function is not shared by the highly homologous protein Bassoon, which indicates that Piccolo has a unique role in coupling the mobilization of SVs in the reserve pool to events within the active zone...
  8. doi request reprint Presynaptic function in health and disease
    Clarissa L Waites
    Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University School of Medicine, 1201 Welch Rd Palo Alto, CA 94304 5485, USA
    Trends Neurosci 34:326-37. 2011
    ..We also discuss potential mechanisms through which the loss or alteration of these specific molecules could lead to defects in synaptic communication, neural circuit function and, ultimately, cognition and behavior...
  9. ncbi request reprint Transsynaptic signaling by postsynaptic synapse-associated protein 97
    Maria Paz Regalado
    Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University, Palo Alto, California 94304 5485, USA
    J Neurosci 26:2343-57. 2006
    ....
  10. ncbi request reprint Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines
    Haiyan Li
    Graduate Programs in Neuroscience and Cell Biology, Department of Neurology and Physiology, UCSF School of Medicine, 600 16th Street, San Francisco, California 94143, USA
    Neuron 48:619-33. 2005
    ..VMAT2 thus defines a population of secretory vesicles that mediate the activity-dependent somatodendritic release of multiple retrograde signals involved in synaptic function, growth, and plasticity...

Research Grants1

  1. The role of dense core vesicles in synapse formation
    CLARISSA WAITES; Fiscal Year: 2005
    ..In the third specific aim, we will use antisense RNAs to reduce or eliminate DCVs in developing neurons, then examine how synapse formation is affected. ..