Marija Vrljic

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Cholesterol depletion suppresses the translational diffusion of class II major histocompatibility complex proteins in the plasma membrane
    Marija Vrljic
    Biophysics Program, Stanford University, Stanford, California 94305 5080, USA
    Biophys J 88:334-47. 2005
  2. pmc Cholesterol depletion induces solid-like regions in the plasma membrane
    Stefanie Y Nishimura
    Department of Chemistry, Molecular and Cellular Physiology, and Biophysics Program, Stanford University, Stanford, California 94305 5080, USA
    Biophys J 90:927-38. 2006
  3. pmc Translational diffusion of individual class II MHC membrane proteins in cells
    Marija Vrljic
    Biophysics Program, Stanford University, Stanford, CA 94305 5080, USA
    Biophys J 83:2681-92. 2002
  4. pmc Three-dimensional molecular modeling with single molecule FRET
    Axel T Brunger
    The Howard Hughes Medical Institute, Stanford University, CA 94305, USA
    J Struct Biol 173:497-505. 2011
  5. ncbi request reprint Single-molecule tracking
    Marija Vrljic
    Dept of Chemistry, Stanford University, CA 94305, USA
    Methods Mol Biol 398:193-219. 2007
  6. pmc Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
    Jiajie Diao
    Departments of Molecular and Cellular Physiology, Neurology and Neurological Sciences, Structural Biology, Photon Science and Howard Hughes Medical Institute, Stanford University, Stanford, USA
    elife 1:e00109. 2012
  7. pmc In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
    Minjoung Kyoung
    Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, 318 Campus Drive West, Stanford, CA 94305 5432, USA
    Proc Natl Acad Sci U S A 108:E304-13. 2011
  8. pmc Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1
    Marija Vrljic
    Department of Molecular and Cellular Physiology, Stanford University, Stanford, California 94305 5432, USA
    Biochemistry 50:9998-10012. 2011
  9. pmc Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion
    Marija Vrljic
    Department of Molecular and Cellular Physiology, Stanford University, Stanford, California, USA
    Nat Struct Mol Biol 17:325-31. 2010
  10. ncbi request reprint Liquid-liquid immiscibility in membranes
    Harden M McConnell
    Department of Chemistry, Biophysics Program, Stanford University, Stanford, California 94305 5080, USA
    Annu Rev Biophys Biomol Struct 32:469-92. 2003

Collaborators

Detail Information

Publications13

  1. pmc Cholesterol depletion suppresses the translational diffusion of class II major histocompatibility complex proteins in the plasma membrane
    Marija Vrljic
    Biophysics Program, Stanford University, Stanford, California 94305 5080, USA
    Biophys J 88:334-47. 2005
    ..That is, cholesterol extraction destroys liquid cholesterol-phospholipid complexes, leaving solid-like high melting phospholipid domains that inhibit the lateral diffusion of membrane components...
  2. pmc Cholesterol depletion induces solid-like regions in the plasma membrane
    Stefanie Y Nishimura
    Department of Chemistry, Molecular and Cellular Physiology, and Biophysics Program, Stanford University, Stanford, California 94305 5080, USA
    Biophys J 90:927-38. 2006
    ..Cytoskeletal effects appear to be minimal. These results are consistent with a previously described model of solid-like domain formation in the plasma membrane...
  3. pmc Translational diffusion of individual class II MHC membrane proteins in cells
    Marija Vrljic
    Biophysics Program, Stanford University, Stanford, CA 94305 5080, USA
    Biophys J 83:2681-92. 2002
    ..Both analyses show that motion is predominantly Brownian. This study finds no strong evidence for significant confinement of either GPI-linked or native I-E(k) in the plasma membrane of CHO cells...
  4. pmc Three-dimensional molecular modeling with single molecule FRET
    Axel T Brunger
    The Howard Hughes Medical Institute, Stanford University, CA 94305, USA
    J Struct Biol 173:497-505. 2011
    ....
  5. ncbi request reprint Single-molecule tracking
    Marija Vrljic
    Dept of Chemistry, Stanford University, CA 94305, USA
    Methods Mol Biol 398:193-219. 2007
    ....
  6. pmc Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
    Jiajie Diao
    Departments of Molecular and Cellular Physiology, Neurology and Neurological Sciences, Structural Biology, Photon Science and Howard Hughes Medical Institute, Stanford University, Stanford, USA
    elife 1:e00109. 2012
    ..Synaptic proteins may have evolved to select this immediate pathway out of a heterogeneous network of possible membrane fusion pathways.DOI:http://dx.doi.org/10.7554/eLife.00109.001...
  7. pmc In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
    Minjoung Kyoung
    Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, 318 Campus Drive West, Stanford, CA 94305 5432, USA
    Proc Natl Acad Sci U S A 108:E304-13. 2011
    ....
  8. pmc Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1
    Marija Vrljic
    Department of Molecular and Cellular Physiology, Stanford University, Stanford, California 94305 5432, USA
    Biochemistry 50:9998-10012. 2011
    ..These results suggest a conserved lipid binding mechanism in which Ca(2+)-independent interactions are mediated via a lysine rich region of the C2B domain while Ca(2+)-dependent interactions are mediated via the Ca(2+)-binding loops...
  9. pmc Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion
    Marija Vrljic
    Department of Molecular and Cellular Physiology, Stanford University, Stanford, California, USA
    Nat Struct Mol Biol 17:325-31. 2010
    ..The loops resemble the membrane-interacting loops of certain viral fusion proteins in the postfusion state, suggesting unexpected similarities between both fusion systems...
  10. ncbi request reprint Liquid-liquid immiscibility in membranes
    Harden M McConnell
    Department of Chemistry, Biophysics Program, Stanford University, Stanford, California 94305 5080, USA
    Annu Rev Biophys Biomol Struct 32:469-92. 2003
    ..The properties of defined cholesterol-phospholipid mixtures provide a conceptual foundation for the exploration of a number of aspects of the biophysics and biochemistry of animal cell membranes...
  11. ncbi request reprint The structure of the yeast plasma membrane SNARE complex reveals destabilizing water-filled cavities
    Pavel Strop
    Howard Hughes Medical Institute and Department of Molecular and Cellular Physiology, Stanford University, Stanford, California 94305, USA
    J Biol Chem 283:1113-9. 2008
    ..Mutagenesis experiments suggest that the water-filled cavities contribute to the lower stability of the S. cerevisiae complex...
  12. pmc Ensemble molecular dynamics yields submillisecond kinetics and intermediates of membrane fusion
    Peter M Kasson
    Medical Scientist Training and Biophysics Programs, Department of Computer Science, Stanford Synchrotron Radiation Laboratory, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 103:11916-21. 2006
    ....
  13. pmc Both MHC class II and its GPI-anchored form undergo hop diffusion as observed by single-molecule tracking
    Yasuhiro M Umemura
    Membrane Mechanisms Project, International Cooperative Research Project, Japan Science and Technology Agency, Institute for Integrated Cell Material Sciences, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    Biophys J 95:435-50. 2008
    ..These results indicate that the actin-based membrane skeleton influences the diffusion of both transmembrane and GPI-anchored proteins...