H J Vreman

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint Phototherapy: current methods and future directions
    Hendrik J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Semin Perinatol 28:326-33. 2004
  2. doi request reprint Standardized bench method for evaluating the efficacy of phototherapy devices
    H J Vreman
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Acta Paediatr 97:308-16. 2008
  3. ncbi request reprint Concentration of carbon monoxide (CO) in postmortem human tissues: effect of environmental CO exposure
    Hendrik J Vreman
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5208, USA
    J Forensic Sci 51:1182-90. 2006
  4. doi request reprint Quantitating carbon monoxide production from heme by vascular plant preparations in vitro
    Hendrik J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305 5208, USA
    Plant Physiol Biochem 49:61-8. 2011
  5. ncbi request reprint Validation of the Natus CO-Stat End Tidal Breath Analyzer in children and adults
    H J Vreman
    Departments of Pediatric, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Clin Monit Comput 15:421-7. 1999
  6. ncbi request reprint Transcutaneous bilirubinometry: a noninvasive tool for studying newborn jaundiced rats before and after exposure to light
    Hendrik J Vreman
    Department of Pediatrics, Stanford University School of Medicine, CA 94305, USA
    Pediatr Res 59:203-9. 2006
  7. ncbi request reprint Determination of carbon monoxide (CO) in rodent tissue: effect of heme administration and environmental CO exposure
    Hendrik J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Anal Biochem 341:280-9. 2005
  8. ncbi request reprint Reduction of the NO-mediated response in the rat aorta by metalloporphyrins
    H J Vreman
    Department of Pediatrics, Stanford University Medical Center, California 94305, USA
    Can J Physiol Pharmacol 78:457-61. 2000
  9. ncbi request reprint Haem oxygenase activity in human umbilical cord and rat vascular tissues
    H J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, 94305 5119, USA
    Placenta 21:337-44. 2000
  10. ncbi request reprint Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron-ascorbate system
    H J Vreman
    Department of Pediatrics, Neonatal and Developmental Medicine Laboratory, Stanford University School of Medicine, CA 94305 5208, USA
    Can J Physiol Pharmacol 76:1057-65. 1998

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Phototherapy: current methods and future directions
    Hendrik J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Semin Perinatol 28:326-33. 2004
    ....
  2. doi request reprint Standardized bench method for evaluating the efficacy of phototherapy devices
    H J Vreman
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Acta Paediatr 97:308-16. 2008
    ..As phototherapy (PT) devices employ a variety of broadband light sources, we developed and tested a standardized bench method for evaluating the efficacy of some devices...
  3. ncbi request reprint Concentration of carbon monoxide (CO) in postmortem human tissues: effect of environmental CO exposure
    Hendrik J Vreman
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5208, USA
    J Forensic Sci 51:1182-90. 2006
    ..2%, and 69.1% of total hemoglobin, respectively. We conclude that measurements of CO concentration in a variety of tissues can be used as markers for the degree of exogenous CO exposure and the identification of possible causes of death...
  4. doi request reprint Quantitating carbon monoxide production from heme by vascular plant preparations in vitro
    Hendrik J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305 5208, USA
    Plant Physiol Biochem 49:61-8. 2011
    ..We conclude that gas chromatography is uniquely suited for the determination of CO production in pigmented, heterogeneous plant tissue preparations...
  5. ncbi request reprint Validation of the Natus CO-Stat End Tidal Breath Analyzer in children and adults
    H J Vreman
    Departments of Pediatric, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    J Clin Monit Comput 15:421-7. 1999
    ..that also reports end tidal carbon dioxide (ETCO2) and respiratory rate (RR), was compared to established, marketed (predicate) devices in children (n = 39) and adults (n = 48) who are normal or at-risk of elevated CO excretion...
  6. ncbi request reprint Transcutaneous bilirubinometry: a noninvasive tool for studying newborn jaundiced rats before and after exposure to light
    Hendrik J Vreman
    Department of Pediatrics, Stanford University School of Medicine, CA 94305, USA
    Pediatr Res 59:203-9. 2006
    ..Thus, in addition to being a useful tool for evaluating jaundice in human neonates, TcB methodology can be used successfully for the noninvasive monitoring of jaundice in neonatal Gunn rats pre- and postlight exposure...
  7. ncbi request reprint Determination of carbon monoxide (CO) in rodent tissue: effect of heme administration and environmental CO exposure
    Hendrik J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Anal Biochem 341:280-9. 2005
    ..Intestine, lung, testes, and brain contained the lowest CO concentrations...
  8. ncbi request reprint Reduction of the NO-mediated response in the rat aorta by metalloporphyrins
    H J Vreman
    Department of Pediatrics, Stanford University Medical Center, California 94305, USA
    Can J Physiol Pharmacol 78:457-61. 2000
    ..However, heme and ZnPP treatments decreased the -logEC50 and the maximal effects of methacholine, therefore decreasing vasorelaxation. We conclude that when ZnPP is administered in vivo blood pressure should be carefully monitored...
  9. ncbi request reprint Haem oxygenase activity in human umbilical cord and rat vascular tissues
    H J Vreman
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, 94305 5119, USA
    Placenta 21:337-44. 2000
    ..We conclude that the presence of HO activity in cord tissues supports the possibility that CO plays a role in fetoplacental blood flow regulation...
  10. ncbi request reprint Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron-ascorbate system
    H J Vreman
    Department of Pediatrics, Neonatal and Developmental Medicine Laboratory, Stanford University School of Medicine, CA 94305 5208, USA
    Can J Physiol Pharmacol 76:1057-65. 1998
    ..We conclude that CO generation is associated with the process of in vitro lipid peroxidation in tissues with limited antioxidant reserves...
  11. ncbi request reprint Prediction of hyperbilirubinemia in near-term and term infants
    D K Stevenson
    Department of Pediatrics, Lucile Salter Packard Children's Hospital, Stanford, California, USA
    Pediatrics 108:31-9. 2001
    ..Depending on the incidence of hyperbilirubinemia within an institution, the criteria for decision making should vary according to its unique population...
  12. pmc Carbon monoxide detection and biological investigations
    D K Stevenson
    Department of Pediatrics, Stanford University School of Medicine, CA 94305 5208, USA
    Trans Am Clin Climatol Assoc 111:61-75. 2000
    ..It may be shown that the integrity of the heme catabolic pathway, which is ever present and plays a role in every tissue, is central to the existence of most complex organisms...
  13. ncbi request reprint Prediction of hyperbilirubinemia in near-term and term infants
    D K Stevenson
    Department of Pediatrics, Lucile Salter Packard Children's Hospital, Stanford, CA 94305-5208, USA
    J Perinatol 21:S63-72; discussion S83-7. 2001
    ..Depending on the incidence of hyperbilirubinemia within an institution, the criteria for decision making should vary according to its unique population...
  14. ncbi request reprint Carbon monoxide and bilirubin production in neonates
    D K Stevenson
    Department of Pediatrics, Stanford University School of Medicine, CA 94304 1510, USA
    Semin Perinatol 25:85-93. 2001
    ..This report provides a brief overview of these interrelationships in the hope that it may provide insight into the central role this pathway plays in the existence of most organisms...
  15. ncbi request reprint Evaluation of a fully automated end-tidal carbon monoxide instrument for breath analysis
    H J Vreman
    Department of Pediatrics, Stanford University School of Medicine, CA 94305, USA henk vreman
    Clin Chem 42:50-6. 1996
    ..We conclude that this instrument is clinically reliable and can be used to noninvasively measure ETCO in neonates and adults...
  16. pmc Dermal carbon monoxide excretion in neonatal rats during light exposure
    Hendrik J Vreman
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pediatr Res 66:66-9. 2009
    ..We conclude that light-induced elevations in total body CO excretion may be caused by transdermally excreted CO, which is most likely produced through endogenous photosensitizer-mediated photooxidation of dermal biomolecules...
  17. ncbi request reprint The jaundiced newborn. Understanding and managing transitional hyperbilirubinemia
    D K Stevenson
    Division of Neonatal, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
    Minerva Pediatr 54:373-82. 2002
    ..In this review, we will discuss the various risk factors associated with hyperbilirubinemia and describe strategies for the diagnosis and management of transitional hyperbilirubinemia...
  18. doi request reprint In vitro inhibition of heme oxygenase isoenzymes by metalloporphyrins
    R J Wong
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    J Perinatol 31:S35-41. 2011
    ..Although bilirubin production is due to the activity of both HO-1 and HO-2, the inhibition of HO-1 with a relative sparing of HO-2 activity might provide the most selective approach for the treatment of hemolytic disease...
  19. ncbi request reprint Systemic effects of orally-administered zinc and tin (IV) metalloporphyrins on heme oxygenase expression in mice
    Ichiro Morioka
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Pediatr Res 59:667-72. 2006
    ..We conclude that the three Mps are absorbed at different rates in the mouse and affect bilirubin production and HO-1 expression in a tissue- and time-dependent manner...
  20. doi request reprint Inhibition of heme oxygenase activity in newborn mice by azalanstat
    Takeshi Morisawa
    Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Can J Physiol Pharmacol 86:651-9. 2008
    ..Therefore, other imidazole-dioxolanes should be evaluated to determine whether they are more potent than AZA for use in treating neonatal jaundice...
  21. ncbi request reprint Expression and regulation of heme oxygenase isozymes in the developing mouse cortex
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305 5208, USA
    Pediatr Res 60:518-23. 2006
    ..Therefore, we conclude that HO-1 gene expression in the cortex is developmentally-regulated and that methylation of the HO-1 CpG island is not associated with the down-regulation of the gene...
  22. ncbi request reprint Regulation of maternal and fetal hemodynamics by heme oxygenase in mice
    Hui Zhao
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305 5208, USA
    Biol Reprod 78:744-51. 2008
    ....
  23. ncbi request reprint Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1
    Weisheng Zhang
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University Medical Center, Stanford University, Stanford, CA 94305 5208, USA
    J Mol Med (Berl) 80:655-64. 2002
    ..Among the known inhibitors of HO enzyme activity that were evaluated in this study, ZnBG did not significantly affect HO-1 transcription and therefore may be well suited for the prevention of neonatal jaundice...
  24. ncbi request reprint Effects of metalloporphyrins on heme oxygenase-1 transcription: correlative cell culture assays guide in vivo imaging
    Monica Hajdena-Dawson
    Stanford University School of Medicine, USA
    Mol Imaging 2:138-49. 2003
    ..Thus, this study serves as a model for understanding the effects of specific compounds in relation to defined targets using an integrated approach...
  25. ncbi request reprint Transcutaneous bilirubin measurements and serum total bilirubin levels in indigenous African infants
    Tina M Slusher
    Department of Pediatrics, West Virginia University School of Medicine, Morgantown, West Virginia 26506, USA
    Pediatrics 113:1636-41. 2004
    ....
  26. ncbi request reprint Failure to detect elevated levels of carboxyhemoglobin in infants dying from SIDS
    Robert G Meny
    Department of Pediatrics, University of Maryland, Baltimore 21201, USA
    J Forensic Sci 47:660-2. 2002
    ..83%); 48 age-matched controls (0.53+/-0.38%); and three individuals who died from fire related causes (41+/-20%). No statistical differences in COHb levels were detected between blood from SIDS and control infants (p = 0.43)...
  27. ncbi request reprint NICHD Conference on Kernicterus: Research on Prevention of Bilirubin-Induced Brain Injury and Kernicterus: Bench-to-Bedside--Diagnostic Methods and Prevention and Treatment Strategies
    David K Stevenson
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94304 5731, USA
    J Perinatol 24:521-5. 2004
    ....
  28. ncbi request reprint A primer on neonatal jaundice
    David K Stevenson
    Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, Calif, USA
    Adv Pediatr 51:263-88. 2004
  29. ncbi request reprint A prospective randomized controlled study of phototherapy using blue and blue-green light-emitting devices, and conventional halogen-quartz phototherapy
    Daniel S Seidman
    Department of Obstetrics and Gynecology, Chain Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Perinatol 23:123-7. 2003
    ..The devices made of high-intensity gallium nitride light-emitting diodes (LEDs) were also compared to conventional halogen-quartz bulbs phototherapy...
  30. ncbi request reprint Imbalance between production and conjugation of bilirubin: a fundamental concept in the mechanism of neonatal jaundice
    Michael Kaplan
    Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel Faculty of Medicine of the Hebrew University, Jerusalem, Israel
    Pediatrics 110:e47. 2002
    ..The objective of this study was to evaluate the roles of production and conjugation of bilirubin, individually and in combination, in the mechanism of neonatal jaundice...
  31. pmc Effects of sample dilution, peroxidase concentration, and chloride ion on the measurement of unbound bilirubin in premature newborns
    Charles E Ahlfors
    PO Box 2904, Vashon, WA 98070, USA
    Clin Biochem 40:261-7. 2007
    ....
  32. ncbi request reprint (TA)n UGT 1A1 promoter polymorphism: a crucial factor in the pathophysiology of jaundice in G-6-PD deficient neonates
    Michael Kaplan
    Department of Neonatology, Shaare Zedek Medical Center, Jerusalem 91031, Israel
    Pediatr Res 61:727-31. 2007
    ..8 +/- 3.4 mg/dL, p = 0.02). In the steady state, similar rates of hemolysis, but increased PTB in the G-6-PD- deficient, (TA)7/(TA)7 homozygotes, imply that (TA)7/(TA)7, homozygosity is central to increased PTB...
  33. ncbi request reprint Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury
    Edward F Chang
    Department of Neurosurgery, University of California, San Francisco, San Francisco, California 94143 0520, USA
    J Neurosci 23:3689-96. 2003
    ..These findings demonstrate that HO-2 expression protects neurons against TBI by reducing lipid peroxidation via the catabolism of free heme...
  34. ncbi request reprint Measurement of endogenous carbon monoxide formation in biological systems
    Gerald S Marks
    Department of Pharmacology and Toxicology, Queen s University, Kingston, Ontario, Canada, K7L 3N6
    Antioxid Redox Signal 4:271-7. 2002
    ..CO formation ranged from a low of 0.029 nmol/mg of protein/h in chorionic villi of term human placenta to a high of 0.28 nmol/mg of protein/h in rat olfactory receptor neurons in culture and rat liver perfusate...
  35. ncbi request reprint Determination of in vivo carbon monoxide production in laboratory animals via exhaled air
    Ryan A Dercho
    Department of Pharmacology and Toxicology, Queen s University, Kingston, ON, Canada K7L 3N6
    J Pharmacol Toxicol Methods 54:288-95. 2006
    ..Here, we describe a modified flow-through method for the collection and quantitation of CO from small laboratory animals...
  36. ncbi request reprint Heme regulation in traumatic brain injury: relevance to the adult and developing brain
    Edward F Chang
    Department of Neurosurgery, University of California, San Francisco, San Francisco, California 94143 0520, USA
    J Cereb Blood Flow Metab 25:1401-17. 2005
    ..These findings suggest novel clinical therapeutic options for further translational study...
  37. ncbi request reprint Reduction in hospital readmission rates for hyperbilirubinemia is associated with use of transcutaneous bilirubin measurements
    David K Stevenson
    Clin Chem 51:481-2. 2005
  38. ncbi request reprint Heme oxygenase-1 induction may explain the antioxidant profile of aspirin
    Nina Grosser
    Department of Pharmacology and Toxicology, School of Pharmacy, Martin Luther University, Wolfgang Langenbeck Str 4, Halle Saale 06099, Germany
    Biochem Biophys Res Commun 308:956-60. 2003
    ..Induction of HO-1 expression and activity may be a novel mechanism by which aspirin prevents cellular injury under inflammatory conditions and in cardiovascular disease...
  39. ncbi request reprint Phototherapy and photo-oxidation in premature neonates
    Michael Kaplan
    Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel
    Biol Neonate 87:44-50. 2005
    ..The potential for photo-oxidation during phototherapy in premature neonates was assessed by measuring parameters reflective of photo-oxidation...
  40. ncbi request reprint Endothelial protection by pentaerithrityl trinitrate: bilirubin and carbon monoxide as possible mediators
    Stefanie Oberle
    Department of Pharmacology and Toxicology, School of Pharmacy, Martin Luther University, 06120 Halle Saale, Germany
    Exp Biol Med (Maywood) 228:529-34. 2003
    ..Increased HO-1 expression and ensuing formation of bilirubin and carbon monoxide may contribute to and explain the specific antioxidant and antiatherogenic actions of PETN...
  41. ncbi request reprint Heme oxygenase-1 induction may explain the antioxidant profile of pentaerythrityl trinitrate
    Stefanie Oberle
    Department of Pharmacology and Toxicology, School of Pharmacy, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Strasse 4, Halle Saale 06099, Germany
    Biochem Biophys Res Commun 290:1539-44. 2002
    ..Increased HO-1 expression and ensuing formation of cytoprotective bilirubin may contribute to and explain the specific antioxidant and antiatherogenic actions of PETN...
  42. ncbi request reprint Hemolysis and bilirubin conjugation in association with UDP-glucuronosyltransferase 1A1 promoter polymorphism
    Michael Kaplan
    Department of Neonatology, Clinical Genetics Service, Shaare Zedek Medical Center, Faculty of Medicine of the Hebrew University, Jerusalem, Israel
    Hepatology 35:905-11. 2002
    ..The increased hemolysis may contribute to the pathogenesis of increased STB values seen in Gilbert's syndrome, and exacerbate neonatal hyperbilirubinemia associated with the promoter polymorphism...
  43. ncbi request reprint Role of carbon monoxide and nitric oxide in newborn infants with postasphyxial hypoxic-ischemic encephalopathy
    Hendrik J Vreman
    Pediatrics 109:715-6; author reply 715-6. 2002
  44. doi request reprint Oxidative stress and proinflammatory cytokine levels are increased in premature neonates of preeclamptic mothers with HELLP syndrome
    Helen L Torrance
    Perinatal Center, Wilhelmina Children s Hospital, Utrecht, The Netherlands
    Neonatology 94:138-42. 2008
    ..RDS and HELLP syndrome have been associated with oxidative stress and inflammatory processes...
  45. ncbi request reprint End-tidal carbon monoxide corrected for lung volume is elevated in patients with cystic fibrosis
    Suzanne W Terheggen-Lagro
    Department of Pediatric Pulmonology, University Medical Center, Internal Postal Code KH 01 419 0, PO Box 85090, 3508 AB Utrecht, The Netherlands
    Am J Respir Crit Care Med 168:1227-31. 2003
    ..001). We hypothesize that a possible increase in breath CO caused by airway inflammation might be masked by differences in lung volumes between control subjects and patients with CF...
  46. ncbi request reprint Is carbon monoxide-mediated cyclic guanosine monophosphate production responsible for low blood pressure in neonatal respiratory distress syndrome?
    Frank van Bel
    Department of Neonatology, Rm KE 04 123 1, Wilhelmina Children s Hospital, University Medical Center, PO Box 85090, 3508 AB Utrecht, The Netherlands
    J Appl Physiol 98:1044-9. 2005
    ..001). We conclude that a CO-mediated increase in cGMP causes systemic vasodilation with a consequent lower blood pressure and increased need for blood pressure support in preterm infants with RDS...
  47. ncbi request reprint End-tidal carbon monoxide measurements in infant respiratory distress syndrome
    Tannette G Krediet
    Department of Neonatology, Wilhemina Children s Hospital, University Medical Center, Utrecht, The Netherlands
    Acta Paediatr 95:1075-82. 2006
    ..RDS involving inflammatory and oxidative processes may lead to increased production of carbon monoxide (CO)...
  48. pmc Selectivity of imidazole-dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms
    Robert T Kinobe
    Department of Pharmacology and Toxicology, Queen s University, Botterell Hall 521, Kingston, ON, Canada K7L 3N6
    Br J Pharmacol 147:307-15. 2006
    ..These molecules could be used to facilitate studies on the elucidation of physiological roles of HO/CO in biological systems...
  49. ncbi request reprint Management of hyperbilirubinemia and prevention of kernicterus in 20 patients with Crigler-Najjar disease
    Kevin A Strauss
    Clinic for Special Children, 535 Bunker Hill Road, Strasburg, PA 17579, USA
    Eur J Pediatr 165:306-19. 2006
    ..Lessons learned from CND can be applied to screening and therapy of non-hemolytic jaundice in otherwise healthy newborns...
  50. ncbi request reprint Respiratory distress syndrome-associated inflammation is related to early but not late peri/intraventricular hemorrhage in preterm infants
    Tannette G Krediet
    Department of Neonatology and Laboratory of Psychoneuroimmunology and Perinatology, Wilhelmina Children s Hospital, University Medical Center, Utrecht, The Netherlands
    J Pediatr 148:740-6. 2006
    ....