Research Topics
Genomes and Genes
| Matt van de RijnSummaryAffiliation: Stanford University Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Gene expression studies on soft tissue tumorsMatt van de Rijn
Department of Pathology, Stanford University Medical Center, Palo Alto, California 94305, USA
Am J Pathol 161:1531-4. 2002- Determination of stromal signatures in breast carcinomaRobert B West
Department of Pathology, Stanford University Medical Center, Stanford, California, USA
PLoS Biol 3:e187. 2005..Our findings suggest that the host stromal response varies significantly among carcinomas and that gene expression patterns characteristic of soft tissue tumors can be used to discover new markers for normal connective tissue cells... - A compact VEGF signature associated with distant metastases and poor outcomesZhiyuan Hu
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
BMC Med 7:9. 2009..Tumor metastases pose the greatest threat to a patient's survival, and thus, understanding the biology of disseminated cancer cells is critical for developing effective therapies... - Gross genomic alterations and gene expression profiles of high- grade serous carcinoma of the ovary with and without BRCA1 inactivationManohar Pradhan
Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, British Columbia, Canada
BMC Cancer 10:493. 2010..The loss of BRCA1 function due to either germline/somatic mutation or epigenetic silencing is observed in most high-grade serous carcinomas of the ovary... 
Genetics of soft tissue tumorsMatt van de Rijn
Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
Annu Rev Pathol 1:435-66. 2006..Here we describe the known molecular changes in a number of sarcomas and focus on novel scientific approaches that can be expected to lead to improved diagnosis, prognostication, and therapy of sarcoma...- The role of microarray technologies in the study of soft tissue tumoursR B West
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
Histopathology 48:22-31. 2006..This review addresses some of the advantages, problems, and solutions to those problems that come with these technologies... - Applications of microarrays to histopathologyM van de Rijn
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Histopathology 44:97-108. 2004..In this review we give a brief overview of microarray technology and research uses, and discuss potential applications of microarrays in the practice of diagnostic histopathology... - Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcomeMatt van de Rijn
L235 Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
Am J Pathol 161:1991-6. 2002..Moreover, multivariate analysis showed that in node-negative breast carcinoma, expression of these cytokeratins was a prognostic factor independent of tumor size and tumor grade... - Coordinate expression of colony-stimulating factor-1 and colony-stimulating factor-1-related proteins is associated with poor prognosis in gynecological and nongynecological leiomyosarcomaInigo Espinosa
Dept of Pathology, L 235, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305, USA
Am J Pathol 174:2347-56. 2009..2; 95% CI, 1.12 to 16; P = 0.03). Our findings indicate that CSF1 may play an important role in the clinical behavior of LMS that may open a window for new therapeutic reagents... - Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarrayJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Am J Surg Pathol 31:673-80. 2007..We conclude that the detection of S100P and GATA3 protein expression may help distinguish urothelial carcinomas from other genitourinary neoplasms that enter into the differential diagnosis... - The gene expression profile of extraskeletal myxoid chondrosarcomaSubbaya Subramanian
Department of Pathology, Stanford University Medical Center, Stanford, CA 94035, USA
J Pathol 206:433-44. 2005..Small molecule inhibitors for PPARG exist and PPARG could be a potential therapeutic target for EMC... - Variations in stromal signatures in breast and colorectal cancer metastasesJonathan A Webster
Department of Pathology, Stanford University Medical Center, Stanford, CA, USA
J Pathol 222:158-65. 2010..The preservation of the CSF1 macrophage response pattern in metastases lends support to targeting the CSF1 pathway in cancer... 
Prognostic significance of macrophage infiltration in leiomyosarcomasCheng Han Lee
Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
Clin Cancer Res 14:1423-30. 2008..Their presence is associated with poor clinical outcome in a variety of epithelial malignancies. The aim of this study is to examine the prognostic significance of tumor-associated macrophages in sarcomas...- A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumorsInigo Espinosa
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Am J Surg Pathol 32:210-8. 2008..5%) synovial sarcomas among the 935 soft tissue tumors examined showed positive immunostaining for DOG1.1. In addition, DOG1.1 immunoreactivity was seen in fewer cases of carcinoma, melanoma, and seminoma as compared with KIT... - Expression of subtype-specific group 1 leiomyosarcoma markers in a wide variety of sarcomas by gene expression analysis and immunohistochemistryAnne M Mills
Department of Pathology, Stanford University Medical Center, Stanford, CA, USA
Am J Surg Pathol 35:583-9. 2011.... - ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumourBadreddin Edris
Department of Pathology, Stanford University School of Medicine, CA, USA
J Pathol 227:223-33. 2012..Together, these results show that ROR2 is a useful prognostic indicator in the clinical management of these soft-tissue sarcomas and may represent a novel therapeutic target... - hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signatureJacques Lapointe
Department of Pathology, Stanford University, Stanford, CA 94305 51, USA
Am J Surg Pathol 32:205-9. 2008..019). Our findings identify hCAP-D3 as a new biomarker for subtype-1 tumors that improves prognostication, and reveal androgen signaling as an important biologic feature of this potentially clinically favorable molecular subtype... - The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation statusRobert B West
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
Am J Pathol 165:107-13. 2004..Reactivity for DOG1 may aid in the diagnosis of GISTs, including PDGFRA mutants that fail to express KIT antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the KIT tyrosine kinase... - The fibromatosis signature defines a robust stromal response in breast carcinomaAndrew H Beck
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Lab Invest 88:591-601. 2008..Our data demonstrate that the DTF core gene set is a robust descriptor of a distinct stromal response that is associated with improved clinical outcome in breast cancer patients... - Translocation and expression of CSF1 in pigmented villonodular synovitis, tenosynovial giant cell tumor, rheumatoid arthritis and other reactive synovitidesJohn S Cupp
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Am J Surg Pathol 31:970-6. 2007.... - The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumorCheng Han Lee
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Am J Surg Pathol 36:641-53. 2012..Thus, their distinction from typical JAZF1 ESS is important for prognostic and therapeutic purposes... - Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the boneCheng Han Lee
Department of Pathology, Stanford University, Stanford, CA, USA
Mod Pathol 21:531-9. 2008..These findings altogether show that p63 can be used as a diagnostic marker to aid the clinical diagnosis of GCTOB... - The macrophage colony-stimulating factor 1 response signature in breast carcinomaAndrew H Beck
Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
Clin Cancer Res 15:778-87. 2009..The purpose of this study was to define a novel CSF1 response signature and to evaluate its clinical and biological significance in breast cancer... - Gene expression patterns in pancreatic tumors, cells and tissuesAnson W Lowe
Department of Medicine, Stanford University Medical Center, Stanford, California, United States of America
PLoS ONE 2:e323. 2007..This study provides a comprehensive assessment of gene expression for pancreatic tumors, the normal pancreas, and nonneoplastic pancreatic disease... - A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosisJacques Lapointe
Department of Pathology, Stanford University, Stanford, CA 94305 5176, USA
Mod Pathol 20:467-73. 2007.... - Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberansRobert B West
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
Am J Surg Pathol 28:1063-9. 2004..stanford.edu/tma_portal/apod/). We conclude that Apo D is strongly expressed in DFSPs and neural lesions and may be useful in differentiating DFSP from fibrous histiocytoma... - Endogenous versus tumor-specific host response to breast carcinoma: a study of stromal response in synchronous breast primaries and biopsy site changesJulie M Wu
Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA
Clin Cancer Res 17:437-46. 2011..The purpose of this study is to elucidate the basis of this stromal response--whether they are elicited by individual tumors or whether they represent an endogenous host reaction produced by the patient... - Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberansSabine C Linn
Departments of Pathology, Genetics, and Biochemistry, and Howard Hughes Medical Institute, Stanford University Medical Center, Stanford, California 94305, USA
Am J Pathol 163:2383-95. 2003.... - CSF1 expression in nongynecological leiomyosarcoma is associated with increased tumor angiogenesisInigo Espinosa
Department of Pathology, Stanford University Medical Center, Stanford, California, Spain
Am J Pathol 179:2100-7. 2011..Together, these findings suggest an important role for CSF1 and the resulting TAM infiltration in the pathological neovascularization of LMS tumors and provide a rationale for CSF1-targeted therapies in LMS... - Characterization of a novel anti-fatty acid synthase (FASN) antiserum in breast tissueKristin C Jensen
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Mod Pathol 21:1413-20. 2008..In addition, FASN expression is described in apocrine metaplasia, columnar cell lesions, and flat epithelial atypia... - The Stanford Tissue Microarray DatabaseRobert J Marinelli
Department of Biochemistry, Stanford University School of Medicine, Howard Hughes Medical Institute, Stanford, CA, USA
Nucleic Acids Res 36:D871-7. 2008..The production server uses the Apache HTTP Server, Oracle Database and Perl application code. Source code is available to interested researchers under a no-cost license... - Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271Alexander D Boiko
Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cancer Center, Stanford University School of Medicine, Stanford, California 94304 5542, USA
Nature 466:133-7. 2010.... - A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancerSameer Malhotra
Department of Urology, Stanford University, Stanford, California, United States of America
PLoS ONE 6:e20293. 2011..Our findings highlight the potential value of a multi-gene signature-based diagnostic, and define a tri-marker proliferation index with possible utility for improved prognostication and treatment stratification in prostate cancer... - Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcomaBadreddin Edris
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 109:6656-61. 2012..These data suggest that treatment with anti-CD47 antibodies not only reduces primary tumor size but can also be used to inhibit the development of, or to eliminate, metastatic disease... - Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumorsNorman L Lehman
Department of Pathology, MC5324, Stanford University, Stanford, CA, USA
Am J Pathol 170:1793-805. 2007..This profile of misregulated mitotic APC/C substrates and regulators in malignant tumors suggests that analysis of this pathway may be diagnostically useful and represent a potentially important therapeutic target... - Gene expression profiling identifies clinically relevant subtypes of prostate cancerJacques Lapointe
Department of Pathology, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 101:811-6. 2004..Our results suggest that prostate tumors can be usefully classified according to their gene expression patterns, and these tumor subtypes may provide a basis for improved prognostication and treatment stratification... - High-resolution array-based comparative genomic hybridization for distinguishing paraffin-embedded Spitz nevi and melanomasJeff D Harvell
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Diagn Mol Pathol 13:22-5. 2004.... - Gene expression in the normal adult human kidney assessed by complementary DNA microarrayJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
Mol Biol Cell 15:649-56. 2004..The distinctive patterns of gene expression in discrete portions of the kidney may serve as a resource for further understanding of renal physiology and the molecular and cellular organization of the nephron... - Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and woundsHoward Y Chang
Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA
PLoS Biol 2:E7. 2004..Thus, the transcriptional signature of the response of fibroblasts to serum provides a possible link between cancer progression and wound healing, as well as a powerful predictor of the clinical course in several common carcinomas... - Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma: a tissue microarray study of 71 primary tumors including correlation with molecular phenotypeAmy Heerema-McKenney
Department of Pathology parallelBiochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
Am J Surg Pathol 32:1513-22. 2008..034) and OS (P=0.0069). In this retrospective analysis, diffuse immunohistochemical reactivity for myogenin in RMS correlates with decreased RFI and OS, independent of histologic subtype, translocation status, tumor site, or stage... - Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growthBadreddin Edris
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305
Proc Natl Acad Sci U S A 110:3501-6. 2013..These results suggest that treatment with mAbs targeting KIT may represent an alternative, or complementary, approach for treating GIST... - The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumorsStephen B Willingham
Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 109:6662-7. 2012..CD47 is therefore a validated target for cancer therapies... - Systematic analysis of breast cancer morphology uncovers stromal features associated with survivalAndrew H Beck
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Sci Transl Med 3:108ra113. 2011..These findings implicate stromal morphologic structure as a previously unrecognized prognostic determinant for breast cancer... - SMURF1 amplification promotes invasiveness in pancreatic cancerKevin A Kwei
Department of Pathology, Stanford University, Stanford, California, United States of America
PLoS ONE 6:e23924. 2011..Together, these findings identify SMURF1 as an amplified oncogene driving multiple tumorigenic phenotypes in pancreatic cancer, and provide a new druggable target for molecularly directed therapy... - Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profilesSubbaya Subramanian
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Oncogene 23:7780-90. 2004..These gene products could serve as highly selective therapeutic targets in GISTs containing the KIT or PDGFRA mutational types with which they are associated... - A DNA microarray survey of gene expression in normal human tissuesRadha Shyamsundar
Department of Pathology, Stanford University School of Medicine, 269 Campus Drive, CCSR 3245A, Stanford, CA 94305 5176, USA
Genome Biol 6:R22. 2005.... - A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cellsRobert B West
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 103:690-5. 2006.... - CDX2 is an amplified lineage-survival oncogene in colorectal cancerKeyan Salari
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 109:E3196-205. 2012..Our findings challenge a prevailing view that CDX2 is a tumor suppressor in colorectal cancer and uncover an additional piece in the multistep model of colorectal tumorigenesis... - A systems biology approach to anatomic diversity of skinJohn L Rinn
Department of Dermatology, Stanford University, Stanford, California, USA
J Invest Dermatol 128:776-82. 2008..The use of gene, tiling, and tissue microarrays together gives a comprehensive view of the gene regulation involved in patterning the skin... - The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasmsKristin C Jensen
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Mod Pathol 20:871-7. 2007..Lastly, we have shown that the lack of its expression at the protein level in many epithelial and mesenchymal neoplasms renders PAX5 expression an extremely specific marker of the B lineage... - Endothelial cell diversity revealed by global expression profilingJen-Tsan Chi
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 100:10623-8. 2003..Tissue-specific expression patterns in different tissue microvascular ECs suggest they are distinct differentiated cell types that play roles in the local physiology of their respective organs and tissues... - Diagnostic implications of podoplanin expression in peripheral nerve sheath neoplasmsChris H Jokinen
Department of Pathology, University of Washington, Seattle, USA
Am J Clin Pathol 129:886-93. 2008..These results suggest diffuse podoplanin expression or coexpression of podoplanin and S-100 is limited to schwannoma and EMPNST and may be useful in the evaluation of these neoplasms... - Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cellsKeith Syson Chan
Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA 94304 5542, USA
Proc Natl Acad Sci U S A 106:14016-21. 2009..Blockade of CD47 by a mAb resulted in macrophage engulfment of bladder cancer cells in vitro. In summary, we have identified a T-IC subpopulation with potential prognostic and therapeutic value for invasive bladder cancer... - Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferationJulie B Sneddon
Department of Biochemistry, Stanford University Medical Center, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 103:14842-7. 2006..Our data suggest that BMP antagonists may be important constituents of tumor stroma, providing a favorable microenvironment for cancer cell survival and expansion in many cancers... - Sox10 and S100 in the diagnosis of soft-tissue neoplasmsJason R Karamchandani
Department of Pathology, Stanford University Medical Center, Palo Alto, CA 94025, USA
Appl Immunohistochem Mol Morphol 20:445-50. 2012..Sox10 should be used in the place of or along with S100 in soft tissue tumor diagnosis... - Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarrayJohn P T Higgins
Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
Am J Pathol 162:925-32. 2003..Characterization of renal cell carcinomas based on gene expression patterns provides a revised classification of these tumors and has the potential to supply significant biological and clinical insights... - The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancerHanna Kim
Department of Pathology, Stanford University, Stanford, California 94305 5176, USA
Cancer Res 65:8118-24. 2005..Taken together, our findings implicate ALDH1a2 as a candidate tumor suppressor gene in prostate cancer and further support a role of retinoids in the prevention or treatment of prostate cancer... - 3'-end sequencing for expression quantification (3SEQ) from archival tumor samplesAndrew H Beck
Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America
PLoS ONE 5:e8768. 2010..These findings demonstrate that 3SEQ is an effective technique for gene expression profiling from archival tumor samples and may facilitate significant advances in translational cancer research... - Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancerKevin A Kwei
Department of Pathology, Stanford University, Stanford, California, United States of America
PLoS Genet 4:e1000081. 2008.... - Gene expression profiles of cutaneous B cell lymphomaMonique N Storz
Department of Pathology, Division of Medical Oncology, Stanford University Medical Center, Stanford, California 94305, USA
J Invest Dermatol 120:865-70. 2003.... - Gene expression patterns in ovarian carcinomasMarci E Schaner
Stanford University School of Medicine, Stanford, California 94305 5151, USA
Mol Biol Cell 14:4376-86. 2003.... - Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sectionsZhen Fan
Department of Pathology L235, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305-5324, USA
Mod Pathol 16:137-44. 2003.... - Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survivalHoward Y Chang
Program in Epithelial Biology, Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 102:3738-43. 2005.... - Gene expression profiling for the investigation of soft tissue sarcoma pathogenesis and the identification of diagnostic, prognostic, and predictive biomarkersAndrew H Beck
Pathology Department, Stanford University Medical Center, Stanford, CA 94305, USA
Virchows Arch 456:141-51. 2010..Lastly, we conclude with a discussion of strategies to further optimize the translation of gene expression data into a greater understanding of sarcoma pathogenesis and improved clinical outcomes for sarcoma patients... - LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factorLihua Ying
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
J Cell Sci 122:1441-51. 2009..Expression profiling of soft tissue tumors revealed increased expression of both LC3 and CTGF in some locally invasive tumor types... - Challenges in developing a molecular characterization of cancerJonathan R Pollack
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
Semin Oncol 29:280-5. 2002..Here, we detail some of the challenges in developing a molecular characterization of cancer and in translating these new discoveries towards clinical utility... - Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphomaMegan L Troxell
Department of Pathology, Stanford University School of Medicine, CA 94305, USA
Appl Immunohistochem Mol Morphol 13:297-303. 2005..Thus, CD21 remains the most reliable marker of follicular dendritic cells in angioimmunoblastic T-cell lymphoma... - Experimental approaches to the study of cancer-stroma interactions: recent findings suggest a pivotal role for stroma in carcinogenesisRobert B West
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
Lab Invest 87:967-70. 2007..Major hurdles in the study of the cancer stroma revolve around the cellular complexity of the tumor microenvironment, both in modeling the microenvironment and discovering/isolating pure populations of stromal cell types... - A novel method for making "tissue" microarrays from small numbers of suspension cellsKelli Montgomery
Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA
Appl Immunohistochem Mol Morphol 13:80-4. 2005..This method is also amenable for use for cultured cells... - Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarraysChih Long Liu
Department of Biochemistry, Stanford University Medical Center, California 94305, USA
Am J Pathol 161:1557-65. 2002..An on-line demonstration of this system is available at http://genome-www.stanford.edu/TMA/explore.shtml... - Diversity, topographic differentiation, and positional memory in human fibroblastsHoward Y Chang
Departments of Dermatology, Biochemistry, Pathology, and Genetics, and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 99:12877-82. 2002....
Research Grants
- Molecular Characterization of Leiomyosarcoma and GISTJAN VAN DE RIJN; Fiscal Year: 2009..abstract_text> ..
- Clinically relevant molecular subtypes in leiomyosarcomaJAN MATT VAN DE RIJN; Fiscal Year: 2010..In this grant we will develop a clinically robust classifier of molecular subtypes of leiomyosarcoma, improve outcome prediction, and identify novel potential treatment options for LMS. ..