Research Topics
| George TriadafilopoulosSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Bowel dysfunction in postmenopausal womenG Triadafilopoulos
Gastroenterology Section, Palo Alto VA Health Care System 111 GI, CA 94304, USA
Women Health 27:55-66. 1998..In this study, we investigated the nature and prevalence of gastrointestinal and irritable bowel syndrome (IBS)-type complaints in women going through their climacteric and postmenopausal periods...
Temperature-controlled radiofrequency energy delivery for gastroesophageal reflux disease: the Stretta procedureG Triadafilopoulos
Section of Gastroenterology, VA Palo Alto Health Care System, California 94304, USA
J Laparoendosc Adv Surg Tech A 11:333-9. 2001..More recently, temperature-controlled RF energy delivery has been applied for the treatment of gastroesophageal reflux disease (GERD)...
Endoscopic therapies for gastroesophageal reflux diseaseGeorge Triadafilopoulos
Gastroenterology Section, Palo Alto Veterans Affairs Health Care System, 111 G1, 3801 Miranda Avenue, Palo Alto, CA 94304, USA
Curr Gastroenterol Rep 4:200-4. 2002..Future trends in endoscopic therapy are discussed...
Belching: dyspepsia or gastroesophageal reflux disease?Mona Lin
Gastroenterology Section, Veterans Affairs Medical Center Palo Alto, and Division of Gastroenterology and Hepatology, Stanford University, Stanford, California 94304, USA
Am J Gastroenterol 98:2139-45. 2003..In this retrospective study we evaluated the prevalence of belching in dyspepsia and GERD and the relation of belching to acid reflux events documented by pH monitoring...
Injection therapies for variceal bleeding disorders of the GI tractWalter G Park
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305, USA
Gastrointest Endosc 67:313-23. 2008
GERD: the potential for endoscopic interventionGeorge Triadafilopoulos
Medical Service, Palo Alto Veterans Affairs Health Care System, Palo Alto, Calif, USA
Dig Dis 22:181-8. 2004....
Detection of endogenous biomolecules in Barrett's esophagus by Fourier transform infrared spectroscopyThomas D Wang
Division of Gastroenterology, Stanford University School of Medicine, Palo Alto Veterans Affairs Health Care System, Palo Alto, CA 94304, USA
Proc Natl Acad Sci U S A 104:15864-9. 2007....
Cost-effectiveness model of endoscopic screening and surveillance in patients with gastroesophageal reflux diseaseLauren B Gerson
Division of Gastroenterology, Stanford University School of Medicine, Stanford, California 94305 5202, USA
Clin Gastroenterol Hepatol 2:868-79. 2004..The cost-effectiveness of screening strategies that incorporate these nonsurgical treatment modalities has not been determined...
Photodynamic therapy for the treatment of patients with Barrett's high-grade dysplasia and mucosal adenocarcinomaGeorge Triadafilopoulos
Division of Gastroenterology and Hepatology, Stanford University, CA 94305-5187, USA
Nat Clin Pract Gastroenterol Hepatol 2:136-7. 2005
Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposureYing Hao
Department of Medicine, Stanford University, Stanford, CA, USA
BMC Gastroenterol 7:24. 2007..In this study, we determined whether similar exposure to acid or bile salts results in gene expression changes that provide insights into malignant transformation...
Endotherapy and surgery for GERDGeorge Triadafilopoulos
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305 5187, USA
J Clin Gastroenterol 41:S87-96. 2007....
Potential relationship between gastroesophageal reflux disease and atrial arrhythmiasLauren B Gerson
Division of Gastroenterology, Stanford University School of Medicine, Stanford, CA 94605 5202, USA
J Clin Gastroenterol 40:828-32. 2006....
Endoscopic therapy for Barrett's esophagusRonald W Yeh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Alway Building M 211, CA 94305, USA
Gastrointest Endosc Clin N Am 15:377-97, vii. 2005..In this article we review current published literature on endoscopic therapies for the management of Barrett's esophagus...
Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicamGurkirpal Singh
Divisions of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
Am J Med 117:100-6. 2004..To assess the risk of serious gastrointestinal and thromboembolic complications with approved doses of meloxicam...
Complete elimination of reflux symptoms does not guarantee normalization of intraesophageal and intragastric pH in patients with gastroesophageal reflux disease (GERD)David Milkes
Department of Medicine; Section of Gastroenterology, VA Palo Alto Health Care System, Palo Alto, California 94304, USA
Am J Gastroenterol 99:991-6. 2004..001). CONCLUSIONS: Fifty percent of patients with GERD without BE continue to exhibit pathologic GERD and low intragastric pH despite PPI therapy that achieves complete reflux symptom control...
Acid- and bile-induced PGE(2) release and hyperproliferation in Barrett's esophagus are COX-2 and PKC-epsilon dependentBaljeet S Kaur
Gastroenterology Section, Veterans Affairs Palo Alto Health Care System, CA 94304, USA
Am J Physiol Gastrointest Liver Physiol 283:G327-34. 2002..The acid- or bile salt-mediated hyperproliferation is related to PGE(2) release. Acid- and bile salt-induced induction of COX-2 and PKC may explain, at least in part, the tumor-promoting effects of acid and bile in BE...
Prevalence of Barrett's esophagus in asymptomatic individualsLauren B Gerson
Section of Gastroenterology, VA Palo Alto Health Care System and Division of Gastroenterology, Stanford University School of Medicine, Stanford, California 94305 5202, USA
Gastroenterology 123:461-7. 2002..We prospectively screened for the presence of BE in asymptomatic subjects older than 50 years of age undergoing screening sigmoidoscopy for colorectal cancer...
Screening for esophageal adenocarcinoma: an evidence-based approachLauren B Gerson
Department of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305 5202, USA
Am J Med 113:499-505. 2002..Several risk factors, including severe reflux symptoms, male sex, and obesity, may identify patients with gastroesophageal reflux disease who are at the greatest risk of the development of cancer...
Clinical experience with the Stretta procedureGeorge Triadafilopoulos
Gastroenterology Section, VA Palo Alto Health Care System, 111 G1, 3801 Miranda Avenue, Palo Alto, CA 94304, USA
Gastrointest Endosc Clin N Am 13:147-55. 2003....
Adverse effects of long-term proton pump inhibitor therapyEdward Sheen
Department of Medicine and Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA
Dig Dis Sci 56:931-50. 2011..The benefits of proton pump inhibitor use outweigh its risks in most patients. Elderly, malnourished, immune-compromised, chronically ill, and osteoporotic patients theoretically could be at increased risk from long-term therapy...
The management of anticoagulants in the periendoscopic period for patients with atrial fibrillation: a decision analysisLauren B Gerson
Division of Gastroenterology, Stanford University School of Medicine, California 94305 5202, USA
Am J Med 116:451-9. 2004..The management of patients who undergo endoscopy while being treated with warfarin is challenging. We used decision analysis to determine the preferred strategy to manage anticoagulants in the periendoscopic period...
Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I StudyGurkirpal Singh
Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, Calif 94301, USA
Am J Med 119:255-66. 2006..To evaluate the efficacy and upper gastrointestinal (UGI) safety of celecoxib, compared with nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), among patients with osteoarthritis...
The Stretta procedure for the treatment of GERD: 6 and 12 month follow-up of the U.S. open label trialGeorge Triadafilopoulos
Gastroenterology and Otolaryngology-Head and Neck Surgery Sections, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
Gastrointest Endosc 55:149-56. 2002..CONCLUSION: The Stretta procedure significantly improves GERD symptoms, quality of life, and esophageal acid exposure and eliminates the need for antisecretory medication in the majority of patients at 12 months...
A novel device for ablation of abnormal esophageal mucosa (with video)Shai Friedland
Stanford University, Palo Alto, CA, USA
Gastrointest Endosc 74:182-8. 2011..Current ablation devices for Barrett's esophagus are effective but have significant limitations...
Rofecoxib inhibits cyclooxygenase 2 expression and activity and reduces cell proliferation in Barrett's esophagusBaljeet S Kaur
Gastroenterology Section, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA
Gastroenterology 123:60-7. 2002..Together with acid suppressive therapy, rofecoxib may be a promising chemoprevention agent against dysplasia and esophageal adenocarcinoma...
The association between cholecystectomy and gastroesophageal reflux symptoms: a prospective controlled studyOtto S Lin
Gastroenterology Section, Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA 98101, USA
Ann Surg 251:40-5. 2010..A large controlled prospective observational study to compare pre- and postsurgery changes in reflux symptoms between cholecystectomy and hernia repair surgery patients...
Use of health care resources and cost of care for adults with constipationGurkirpal Singh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California, USA
Clin Gastroenterol Hepatol 5:1053-8. 2007..To evaluate the clinical and fiscal effects of constipation, we assessed health care resource use by patients with constipation enrolled in a large state Medicaid program...
Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugsC Mel Wilcox
Department of Medicine, Division of Gastroenterology, University of Alabama at Birmingham, Alabama 35294 0007, USA
J Rheumatol 32:2218-24. 2005..To assess the frequency and indications for over-the-counter (OTC) nonsteroidal antiinflammatory drug (NSAID) use and to what degree the public is aware of their side effects...
Stretta: an effective, minimally invasive treatment for gastroesophageal reflux diseaseGeorge Triadafilopoulos
Stanford University School of Medicine, Stanford, California, USA
Am J Med 115:192S-200S. 2003....
Time esophageal pH < 4 overestimates the prevalence of pathologic esophageal reflux in subjects with gastroesophageal reflux disease treated with proton pump inhibitorsLauren B Gerson
Stanford University School of Medicine, Stanford, CA, USA
BMC Gastroenterol 8:15. 2008..A Stanford University study reported that in asymptomatic GERD patients who were being treated with a proton pump inhibitor (PPI), 50% had pathologic esophageal acid exposure...
Features of gastroesophageal reflux disease in womenMona Lin
Division of Gastroenterology, Stanford University School of Medicine, Stanford, California, USA
Am J Gastroenterol 99:1442-7. 2004..The severity of symptoms in women is significantly more than in men and may contribute to earlier disease recognition and different disease management...
Five-year colon surveillance after screening colonoscopyDavid A Lieberman
Department of Veterans Affairs Medical Center, Portland, Oregon 97239, USA
Gastroenterology 133:1077-85. 2007..Outcomes of colon surveillance after colorectal cancer screening with colonoscopy are uncertain. We conducted a prospective study to measure incidence of advanced neoplasia in patients within 5.5 years of screening colonoscopy...
Injection therapies for nonvariceal bleeding disorders of the GI tractWalter G Park
Division of Gastroenterology and Hepatology, Stanford University, Stanford, California 94305, USA
Gastrointest Endosc 66:343-54. 2007
Cost-effectiveness of photodynamic therapy for high-grade dysplasia in Barrett's esophagusRohini Vij
Division of Gastroenterology and Hepatology, Center for Primary Care and Outcomes Research, Department of Medicine, Stanford University School of Medicine, California, USA
Gastrointest Endosc 60:739-56. 2004..Clinical trials directly comparing these strategies are warranted...
Patient-derived health state utilities for gastroesophageal reflux diseaseLauren B Gerson
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA
Am J Gastroenterol 100:524-33. 2005..CONCLUSION: Gastroesophageal reflux disease adversely affects health-related quality of life. Time-tradeoff utility for patients with reflux disease is substantially higher when patients are on medication than off medications...
Endotherapy for GERD: angels and demonsGeorge Triadafilopoulos
Gastrointest Endosc 61:668-70. 2005
Circumferential ablation of Barrett's esophagus that contains high-grade dysplasia: a U.S. Multicenter RegistryRobert A Ganz
Minnesota Gastroenterology, Plymouth, Minnesota 55446, USA
Gastrointest Endosc 68:35-40. 2008..The management strategies for Barrett's esophagus (BE) that contains high-grade dysplasia (HGD) include intensive endoscopic surveillance, photodynamic therapy, thermal ablation, EMR, and esophagectomy...
Submucosal injection: safety cushion at what cost?Ronald W Yeh
Gastrointest Endosc 62:943-5. 2005
Endoscopic antireflux therapy: the Stretta procedureRonald W Yeh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Alway Building M-211, 300 Pasteur Drive, Stanford, CA 94305, USA
Thorac Surg Clin 15:395-403. 2005....
Colorectal neoplasia in veterans is associated with Barrett's esophagus but not with proton-pump inhibitor or aspirin/NSAID usePeter D Siersema
Departments of Gastroenterology and Hepatology and Public Health, Erasmus MC-University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands
Gastrointest Endosc 63:581-6. 2006..LIMITATIONS: This was a retrospective study in mostly male veterans. CONCLUSIONS: Veterans with BE are at an increased risk of developing colorectal neoplasia. This association is independent from the use of PPIs or aspirin/NSAIDs...
Bravura for Bravo pH monitoringGeorge Triadafilopoulos
Gastrointest Endosc 63:1051-4. 2006
Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinomaYing Hao
Department of Medicine, Stanford University, Stanford, California 94305-5187, USA
Gastroenterology 131:925-33. 2006..Stromal gene expression in Barrett's esophagus and adenocarcinoma is similar, indicating that these changes precede malignant transformation...
Autofluorescence imaging: have we finally seen the light?Thomas D Wang
Gastrointest Endosc 61:686-8. 2005
Clinical, radiologic, and manometric characteristics of chronic intestinal dysmotility: the Stanford experienceLucilene Rosa-E-Silva
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305, USA
Clin Gastroenterol Hepatol 4:866-73. 2006..Because any segment of the GI tract may be involved in CID, functional assessment of the entire GI tract is recommended. CID presents several unmet clinical needs even in tertiary centers with expertise...
Nonsteroidal anti-inflammatory drug use does not affect short-term endoscopic and histologic outcomes after Helicobacter pylori eradication in patients with rheumatoid arthritisEiichi Tanaka
Institute of Rheumatology, Tokyo Women s Medical University, Tokyo 162 0054, Japan
Mod Rheumatol 17:228-34. 2007..5 months, use of NSAIDs in Japanese patients with RA did not impair the healing process of gastric and duodenal ulcers nor did it affect the endoscopic and histological improvements associated with H. pylori eradication...
Exercise and gastrointestinal function and disease: an evidence-based review of risks and benefitsLuke Bi
Division of Gastroenterology, Department of Medicine, College of Medicine, University of California at Irvine, Orange, CA, USA
Clin Gastroenterol Hepatol 1:345-55. 2003..Our understanding of exercise and its gastrointestinal manifestations as well as risks and benefits warrants further investigation...
Low proportion of Barrett's esophagus in Asian AmericansKhoa D Lam
Stanford University, Stanford, California, USA
Am J Gastroenterol 103:1625-30. 2008..To determine the proportion of Barrett's esophagus (BE) in Asians versus non-Asians and the predictors of BE in patients with upper gastrointestinal (GI) symptoms...
Guide to the use of proton pump inhibitors in adult patientsVandana Boparai
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305 5187, USA
Drugs 68:925-47. 2008..Various clinical endpoints, such as symptom relief, mucosal healing, prevention of disease recurrence or complications, and cancer chemoprevention, are discussed and unmet needs are highlighted...
A message from the Editor-in-Chief: GIE at the frontier of endoscopyGeorge Triadafilopoulos
Gastrointest Endosc 61:99-101. 2005
Neuro-regulation of lower esophageal sphincter function as treatment for gastroesophageal reflux diseaseAnupender Singh Sidhu
World J Gastroenterol 14:985-90. 2008..Alterations of the structure and function of the EGJ and the LES may predispose to gastroesophageal reflux disease (GERD)...
Communicating with patients with inflammatory bowel diseaseAli Husain
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
Inflamm Bowel Dis 10:444-50; discussion 451. 2004..We hope that our review will form a framework by which different members of the medical team learn their roles in the complex management decisions affecting IBD patients...
Injection therapies for nonbleeding disorders of the GI tractRonald W Yeh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA
Gastrointest Endosc 64:399-411; quiz 389-92. 2006
Interventional upper endoscopy: the adult perspectiveTonya Kaltenbach
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 300 Pasteur Drive, Alway Building M 211, Stanford, CA 94305, USA
Curr Gastroenterol Rep 8:443-9. 2006....
