Jean Y Tang

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Vitamin D in cutaneous carcinogenesis: part I
    Jean Y Tang
    Department of Dermatology, Stanford University, Stanford, CA 94305, USA
    J Am Acad Dermatol 67:803.e1-12, quiz 815-6. 2012
  2. pmc Vitamin D in cutaneous carcinogenesis: part II
    Jean Y Tang
    Department of Dermatology, Stanford University, Stanford, California 94305, USA
    J Am Acad Dermatol 67:817.e1-11; quiz 827-8. 2012
  3. pmc Novel Hedgehog pathway targets against basal cell carcinoma
    Jean Y Tang
    Department of Dermatology, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Toxicol Appl Pharmacol 224:257-64. 2007
  4. doi request reprint Elucidating the role of molecular signaling pathways in the tumorigenesis of basal cell carcinoma
    Jean Y Tang
    Stanford University School of Medicine, Palo Alto, California, USA
    Semin Cutan Med Surg 30:S6-9. 2011
  5. doi request reprint Emerging treatments and signaling pathway inhibitors
    Jean Y Tang
    Stanford University School of Medicine, Palo Alto, California, USA
    Semin Cutan Med Surg 30:S14-8. 2011
  6. pmc Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trials
    Jean Y Tang
    Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA 94305, USA
    J Natl Cancer Inst 103:1469-75. 2011
  7. pmc Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial
    Jean Y Tang
    Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA, USA
    J Clin Oncol 29:3078-84. 2011
  8. pmc Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly men
    Jean Y Tang
    Children s Hospital of Oakland Research Institute, USA
    Cancer Causes Control 21:387-91. 2010
  9. pmc Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas
    Jean Y Tang
    Department of Dermatology, Stanford University School of Medicine, Redwood City, CA 94063 5334, USA
    Cancer Prev Res (Phila) 4:744-51. 2011
  10. pmc High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome
    Jean Y Tang
    Department of Dermatology, Stanford University Medical Center, 450 Broadway St, Pavilion C, Redwood City, CA 94063, USA
    Arch Dermatol 146:1105-10. 2010

Collaborators

Detail Information

Publications32

  1. pmc Vitamin D in cutaneous carcinogenesis: part I
    Jean Y Tang
    Department of Dermatology, Stanford University, Stanford, CA 94305, USA
    J Am Acad Dermatol 67:803.e1-12, quiz 815-6. 2012
    ..Part I will review the role of vitamin D in the epidermis; part II will review the role of vitamin D in keratinocyte-derived tumors to help frame the discussion on the possible role of vitamin D in the prevention of skin cancer...
  2. pmc Vitamin D in cutaneous carcinogenesis: part II
    Jean Y Tang
    Department of Dermatology, Stanford University, Stanford, California 94305, USA
    J Am Acad Dermatol 67:817.e1-11; quiz 827-8. 2012
    ....
  3. pmc Novel Hedgehog pathway targets against basal cell carcinoma
    Jean Y Tang
    Department of Dermatology, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Toxicol Appl Pharmacol 224:257-64. 2007
    ..Thus, sterols may be a new therapeutic target for the treatment of BCCs, and readily available agents such as statins (HMG-CoA reductase inhibitors) or vitamin D might be helpful in reducing BCC incidence...
  4. doi request reprint Elucidating the role of molecular signaling pathways in the tumorigenesis of basal cell carcinoma
    Jean Y Tang
    Stanford University School of Medicine, Palo Alto, California, USA
    Semin Cutan Med Surg 30:S6-9. 2011
    ..To date, several agents have been developed-and some are in clinical trials-that hold promise for improved nonsurgical treatments for patients with Gorlin syndrome and those with locally advanced/metastatic BCCs...
  5. doi request reprint Emerging treatments and signaling pathway inhibitors
    Jean Y Tang
    Stanford University School of Medicine, Palo Alto, California, USA
    Semin Cutan Med Surg 30:S14-8. 2011
    ....
  6. pmc Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trials
    Jean Y Tang
    Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA 94305, USA
    J Natl Cancer Inst 103:1469-75. 2011
    ....
  7. pmc Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial
    Jean Y Tang
    Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA, USA
    J Clin Oncol 29:3078-84. 2011
    ....
  8. pmc Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly men
    Jean Y Tang
    Children s Hospital of Oakland Research Institute, USA
    Cancer Causes Control 21:387-91. 2010
    ..026) compared to those in the lowest quintile. Our results suggest that a diagnosis of NMSC is not a surrogate for adequate 25(OH)D levels or increased UV exposure, and high 25(OH)D levels may be associated with a reduced risk of NMSC...
  9. pmc Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas
    Jean Y Tang
    Department of Dermatology, Stanford University School of Medicine, Redwood City, CA 94063 5334, USA
    Cancer Prev Res (Phila) 4:744-51. 2011
    ..Finally, topical vitamin D3 treatment of existing murine BCC tumors significantly decreases Gli1 and Ki67 staining. Thus, topical vitamin D3 acting via its HH inhibiting effect may hold promise as an effective anti-BCC agent...
  10. pmc High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome
    Jean Y Tang
    Department of Dermatology, Stanford University Medical Center, 450 Broadway St, Pavilion C, Redwood City, CA 94063, USA
    Arch Dermatol 146:1105-10. 2010
    ..To evaluate vitamin D status in patients with basal cell nevus syndrome (BCNS) who practice photoprotection because of their genetic predisposition to skin cancer and to determine risk factors for deficiency...
  11. pmc Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women's Health Initiative
    Christina A Gamba
    Stanford University School of Medicine and Cancer Institute, Stanford, California, USA
    Cancer 119:1562-9. 2013
    ..However, the impact of NSAIDs on the risk of melanoma has been inconsistent. The authors evaluated the association between NSAID use and cutaneous melanoma risk in the Women's Health Initiative (WHI) Observational Study (OS)...
  12. pmc Sun protective behaviors and vitamin D levels in the US population: NHANES 2003-2006
    Eleni Linos
    Department of Dermatology, Stanford University School of Medicine, Pavilion B 2nd Floor, 450 Broadway St, Redwood City, CA 94063, USA
    Cancer Causes Control 23:133-40. 2012
    ..Our aim was to investigate the relationship between different types of sun protective behaviors and serum 25(OH)D levels in the general US population...
  13. pmc Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists
    James Kim
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
    Cancer Cell 23:23-34. 2013
    ..Itraconazole and arsenic trioxide, alone or in combination, inhibit the growth of medulloblastoma and basal cell carcinoma in vivo, and prolong survival of mice with intracranial drug-resistant SMO(D477G) medulloblastoma...
  14. pmc Low-fat diet and skin cancer risk: the women's health initiative randomized controlled dietary modification trial
    Christina S Gamba
    Stanford School of Medicine, Stanford University, Stanford, USA
    Cancer Epidemiol Biomarkers Prev 22:1509-19. 2013
    ..In animal studies, skin tumor development has been reduced by low-fat diet. We evaluated the effect of a low-fat dietary pattern on NMSC and melanoma in the Women's Health Initiative Dietary Modification trial...
  15. pmc Lower skin cancer risk in women with higher body mass index: the women's health initiative observational study
    Jean Y Tang
    Authors Affiliations Stanford School of Medicine, Quantitative Sciences Unit, Department of Medicine, and Stanford Prevention Research Center, Stanford University, Stanford, California Medstar, Hyattsville, Maryland Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee and Fred Hutchinson Cancer Research Center, Seattle, Washington
    Cancer Epidemiol Biomarkers Prev 22:2412-5. 2013
    ..This supports previous work demonstrating the relationship between excess body weight and skin cancer risk...
  16. pmc Association of facial skin aging and vitamin D levels in middle-aged white women
    Anne Lynn S Chang
    Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA 94305, USA
    Cancer Causes Control 21:2315-6. 2010
    ..Our results suggest an association between skin aging and 25(OH)D levels...
  17. pmc Hat, shade, long sleeves, or sunscreen? Rethinking US sun protection messages based on their relative effectiveness
    Eleni Linos
    Department of Dermatology, Stanford University School of Medicine, 450 Broadway St, Pavillion C, Redwood City, CA 94063, USA
    Cancer Causes Control 22:1067-71. 2011
    ..Sun protection messages in the United States emphasize sunscreen use, although its efficacy in skin cancer prevention remains controversial...
  18. doi request reprint Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma
    Daniel J Kim
    Daniel J Kim, James Kim, Katrina Spaunhurst, Rita Khodosh, Kalyani Chandra, Teresa Fu, Philip A Beachy, and Jean Y Tang, Stanford University, Stanford Anita Gilliam, Palo Alto Medical Foundation, Palo Alto, CA James Kim, University of Texas Southwestern, Dallas, TX Javier Montoya and Monserrat Molgo, Universidad Catolica de Chile, Santiago, Chile
    J Clin Oncol 32:745-51. 2014
    ..We assessed the effect of itraconazole on the HH pathway and on tumor size in human BCC tumors...
  19. doi request reprint Quantifying soft tissue loss in facial aging: a study in women using magnetic resonance imaging
    Ashley Wysong
    Department of Dermatology, School of Medicine, Stanford University, Redwood City, California Scripps Clinic, La Jolla, California
    Dermatol Surg 39:1895-902. 2013
    ..Facial aging involves changes in the facial skeleton and soft tissues. There is limited quantitative data on soft tissue aging of the face...
  20. doi request reprint Eczema and sensitization to common allergens in the United States: a multiethnic, population-based study
    Teresa Fu
    Department of Dermatology, School of Medicine, Stanford University, Redwood City, California
    Pediatr Dermatol 31:21-6. 2014
    ..U.S. children with eczema are most likely to be sensitized to dog dander. Future prospective studies should further explore this relationship...
  21. doi request reprint Alcohol consumption and risk of melanoma and non-melanoma skin cancer in the Women's Health Initiative
    Jessica T Kubo
    Quantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, 1070 Arastradero Road 3C03A, Palo Alto, CA, 94304, USA
    Cancer Causes Control 25:1-10. 2014
    ..The relationship between alcohol consumption and preference of alcohol type with hazard of melanoma (MM) and risk of non-melanoma skin cancer (NMSC) was examined in the Women's Health Initiative (WHI) Observational Study (OS)...
  22. ncbi request reprint Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth
    James Kim
    Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA
    Cancer Cell 17:388-99. 2010
    ....
  23. doi request reprint Nonmelanoma skin cancer visits and procedure patterns in a nationally representative sample: national ambulatory medical care survey 1995-2007
    Ashley Wysong
    Department of Dermatology, School of Medicine, Stanford University, Redwood City, California, USA
    Dermatol Surg 39:596-602. 2013
    ..The rising incidence of nonmelanoma skin cancer (NMSC) is well documented, but data are limited on the number of visits and treatment patterns of NMSC in the outpatient setting...
  24. ncbi request reprint Lack of efficacy with 1064-nm neodymium:yttrium-aluminum-garnet laser for the treatment of onychomycosis: a randomized, controlled trial
    S Tyler Hollmig
    Department of Dermatology, Stanford University Medical Center, Stanford, California Electronic address
    J Am Acad Dermatol 70:911-7. 2014
    ..Laser therapies have been Food and Drug Administration approved for temporary nail plate clearance; however, there is minimal evidence of their long-term efficacy...
  25. ncbi request reprint The use of vismodegib to shrink keratocystic odontogenic tumors in patients with Basal cell nevus syndrome
    Mina S Ally
    Department of Dermatology, Stanford University, Redwood City, California
    JAMA Dermatol 150:542-5. 2014
    ..These effects were maintained for at least 9 months after drug cessation in 1 patient. Further studies assessing long-term efficacy and optimal maintenance regimens should be performed. ..
  26. pmc Cutaneous human papillomavirus infection and Basal cell carcinoma of the skin
    Mina S Ally
    Department of Dermatology, Stanford University School of Medicine, Redwood City, California 94305, USA
    J Invest Dermatol 133:1456-8. 2013
    ..In contrast to squamous cell carcinoma (SCC), there is no association between HPV and BCC...
  27. doi request reprint Sunscreen use in NCAA collegiate athletes: identifying targets for intervention and barriers to use
    Ashley Wysong
    Department of Dermatology, Stanford University School of Medicine, Redwood City, CA 94036, USA
    Prev Med 55:493-6. 2012
    ..The aim of this study was to identify attitudes, personal characteristics, and barriers associated with sunscreen use among a high-risk athlete population...
  28. pmc GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas
    Scott X Atwood
    Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 494:484-8. 2013
    ..These results demonstrate that aPKC-ι/λ is critical for HH-dependent processes and implicates aPKC-ι/λ as a new, tumour-selective therapeutic target for the treatment of SMO-inhibitor-resistant cancers...
  29. doi request reprint Correlates of low bone mass in children with generalized forms of epidermolysis bullosa
    Anna L Bruckner
    Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305 5168, USA
    J Am Acad Dermatol 65:1001-9. 2011
    ..Epidermolysis bullosa (EB) is a family of rare, heterogeneous, genetic disorders characterized by fragility of the skin and mucous membranes. Reduced bone mass and fractures have been recognized as complications of generalized forms of EB...
  30. doi request reprint The evolving conception and management challenges of malignant fibrous histiocytoma
    S Tyler Hollmig
    Department of Dermatology, Stanford University, 360 Stanford Ave, Palo Alto, CA 94306, USA
    Dermatol Surg 38:1922-9. 2012
    ..Mohs micrographic surgery (MMS) has been reported as an effective treatment, although most cases were published before advances in cytopathologic techniques led to reclassification of many tumors...
  31. doi request reprint Does a history of eczema predict a future basal cell carcinoma?
    Christina A Gamba
    Stanford University School of Medicine, Stanford, California, USA
    J Invest Dermatol 132:2497-9. 2012
    ..In addition to known risk factors for a future BCC, such as number of prior BCCs, a history of eczema and lower education levels were also associated with greater risk...
  32. pmc Genotype-phenotype correlations among pachyonychia congenita patients with K16 mutations
    Teresa Fu
    Department of Dermatology, Stanford University School of Medicine, Stanford, California 94063, USA
    J Invest Dermatol 131:1025-8. 2011
    ..Knowledge of the exact gene defect is likely to assist in predicting disease prognosis and clinical management...