See Ying Tam

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint RabGEF1 is a negative regulator of mast cell activation and skin inflammation
    See Ying Tam
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Immunol 5:844-52. 2004
  2. pmc RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells
    Janet Kalesnikoff
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
    Proc Natl Acad Sci U S A 103:2659-64. 2006
  3. ncbi request reprint RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation
    See Ying Tam
    Departments of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5324, USA
    Novartis Found Symp 271:115-24; discussion 124-30, 145-51. 2005
  4. ncbi request reprint Using mast cell knock-in mice to analyze the roles of mast cells in allergic responses in vivo
    Mindy Tsai
    Department of Pathology, Stanford University School of Medicine, Stanford, Calif 94305, USA edu
    Chem Immunol Allergy 87:179-97. 2005
  5. pmc Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo
    Michele A Grimbaldeston
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
    Am J Pathol 167:835-48. 2005
  6. pmc Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice
    Mindy Tsai
    Stanford University School of Medicine, Department of Pathology, L 235, 300 Pasteur Drive, Stanford, CA 94305 5324, USA
    Am J Pathol 177:2411-20. 2010
  7. pmc Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11
    Koichi Sayama
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    BMC Immunol 3:5. 2002
  8. pmc Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cells
    Janet Kalesnikoff
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
    Blood 109:5308-17. 2007
  9. ncbi request reprint Mast cells derived from embryonic stem cells: a model system for studying the effects of genetic manipulations on mast cell development, phenotype, and function in vitro and in vivo
    Mindy Tsai
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Int J Hematol 75:345-9. 2002
  10. pmc Mast cells can promote the development of multiple features of chronic asthma in mice
    Mang Yu
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305 5324, USA
    J Clin Invest 116:1633-41. 2006

Detail Information

Publications10

  1. ncbi request reprint RabGEF1 is a negative regulator of mast cell activation and skin inflammation
    See Ying Tam
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Immunol 5:844-52. 2004
    ..Thus, RabGEF1 is a negative regulator of Fc epsilon RI-dependent mast cell activation, and a lack of RabGEF1 results in the development of skin inflammation in vivo...
  2. pmc RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells
    Janet Kalesnikoff
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
    Proc Natl Acad Sci U S A 103:2659-64. 2006
    ..Thus, RabGEF1 plays a critical role in the regulation of SCF/c-Kit-mediated signaling events and biological responses in mast cells...
  3. ncbi request reprint RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation
    See Ying Tam
    Departments of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5324, USA
    Novartis Found Symp 271:115-24; discussion 124-30, 145-51. 2005
    ....
  4. ncbi request reprint Using mast cell knock-in mice to analyze the roles of mast cells in allergic responses in vivo
    Mindy Tsai
    Department of Pathology, Stanford University School of Medicine, Stanford, Calif 94305, USA edu
    Chem Immunol Allergy 87:179-97. 2005
    ....
  5. pmc Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo
    Michele A Grimbaldeston
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
    Am J Pathol 167:835-48. 2005
    ..Thus, Kit(W-sh/W-sh) mice represent a useful model for mast cell research, especially for analyzing mast cell function in vivo...
  6. pmc Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice
    Mindy Tsai
    Stanford University School of Medicine, Department of Pathology, L 235, 300 Pasteur Drive, Stanford, CA 94305 5324, USA
    Am J Pathol 177:2411-20. 2010
    ....
  7. pmc Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11
    Koichi Sayama
    Department of Pathology, Stanford University School of Medicine, Stanford, California, USA
    BMC Immunol 3:5. 2002
    ..To search for new mast cell products, we used complementary DNA microarrays to analyze gene expression in human umbilical cord blood-derived mast cells stimulated via the high-affinity IgE receptor (Fc(epsilon)RI)...
  8. pmc Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cells
    Janet Kalesnikoff
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 5324, USA
    Blood 109:5308-17. 2007
    ..By contrast, correction of these -/- phenotypes required a functional Vps9 domain. Thus, Fc epsilon RI-mediated mast cell functional activation is dependent on RabGEF1's GEF activity...
  9. ncbi request reprint Mast cells derived from embryonic stem cells: a model system for studying the effects of genetic manipulations on mast cell development, phenotype, and function in vitro and in vivo
    Mindy Tsai
    Department of Pathology, Stanford University School of Medicine, California 94305, USA
    Int J Hematol 75:345-9. 2002
    ....
  10. pmc Mast cells can promote the development of multiple features of chronic asthma in mice
    Mang Yu
    Department of Pathology, Stanford University School of Medicine, Stanford, California 94305 5324, USA
    J Clin Invest 116:1633-41. 2006
    ....