Holly K Tabor

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Ethical implications of array comparative genomic hybridization in complex phenotypes: points to consider in research
    Holly K Tabor
    Stanford Center for Biomedical Ethics, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA
    Genet Med 9:626-31. 2007
  2. pmc Self-guided management of exome and whole-genome sequencing results: changing the results return model
    Joon Ho Yu
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Genet Med 15:684-90. 2013
  3. pmc Practices and policies of clinical exome sequencing providers: analysis and implications
    Seema M Jamal
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Med Genet A 161:935-50. 2013
  4. pmc Attitudes of African Americans toward return of results from exome and whole genome sequencing
    Joon Ho Yu
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Med Genet A 161:1064-72. 2013
  5. pmc A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Atherosclerosis 198:136-44. 2008
  6. ncbi request reprint Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1035-42. 2007
  7. pmc Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease
    Themistocles L Assimes
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Hum Genet 123:399-408. 2008
  8. pmc Informed consent for whole genome sequencing: a qualitative analysis of participant expectations and perceptions of risks, benefits, and harms
    Holly K Tabor
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Am J Med Genet A 158:1310-9. 2012
  9. pmc Mutations in PIEZO2 cause Gordon syndrome, Marden-Walker syndrome, and distal arthrogryposis type 5
    Margaret J McMillin
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Hum Genet 94:734-44. 2014
  10. doi request reprint Genomics really gets personal: how exome and whole genome sequencing challenge the ethical framework of human genetics research
    Holly K Tabor
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Am J Med Genet A 155:2916-24. 2011

Collaborators

Detail Information

Publications12

  1. pmc Ethical implications of array comparative genomic hybridization in complex phenotypes: points to consider in research
    Holly K Tabor
    Stanford Center for Biomedical Ethics, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA
    Genet Med 9:626-31. 2007
    ..Our goal was to identify points to consider for researchers, clinicians, and patients/families to ensure responsible and ethical design, presentation, and interpretation of these kinds of studies...
  2. pmc Self-guided management of exome and whole-genome sequencing results: changing the results return model
    Joon Ho Yu
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Genet Med 15:684-90. 2013
    ..We describe key challenges and advantages of such a self-guided management system and offer guidance on implementation using an information systems approach...
  3. pmc Practices and policies of clinical exome sequencing providers: analysis and implications
    Seema M Jamal
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Med Genet A 161:935-50. 2013
    ..Approaches toward informed consent, data sharing, and results return vary widely among ES providers as do the overall potential merits and disadvantages of each, and more importantly, the balance between the two...
  4. pmc Attitudes of African Americans toward return of results from exome and whole genome sequencing
    Joon Ho Yu
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Med Genet A 161:1064-72. 2013
    ..This is due in part to different expectations of health benefits from ES/WGS and how results should be managed. Our results underscore the need to develop and test culturally tailored strategies for returning ES/WGS results to AAs...
  5. pmc A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Atherosclerosis 198:136-44. 2008
    ..We tested the hypothesis that exonic and/or promoter single nucleotide polymorphisms (SNPs) in the human 12/15-LOX gene (ALOX15) alter the risk of symptomatic coronary artery disease (CAD)...
  6. ncbi request reprint Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1035-42. 2007
    ..The goal of this study was to assess whether polymorphisms in genes encoding elements of pathways mediating the response to ischemia affect vulnerability to MI among patients with underlying CAD...
  7. pmc Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease
    Themistocles L Assimes
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Hum Genet 123:399-408. 2008
    ..However, additional studies are needed to exclude modest effects of promoter variation in ALOX5 on the risk of CAD assuming a recessive mode of inheritance...
  8. pmc Informed consent for whole genome sequencing: a qualitative analysis of participant expectations and perceptions of risks, benefits, and harms
    Holly K Tabor
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Am J Med Genet A 158:1310-9. 2012
    ..Web-based tools that facilitate participant management of their individual research results could accommodate such a framework...
  9. pmc Mutations in PIEZO2 cause Gordon syndrome, Marden-Walker syndrome, and distal arthrogryposis type 5
    Margaret J McMillin
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Hum Genet 94:734-44. 2014
    ..0001). Collectively, although GS, DA5, and MWS have traditionally been considered separate disorders, our findings indicate that they are etiologically related and perhaps represent variable expressivity of the same condition. ..
  10. doi request reprint Genomics really gets personal: how exome and whole genome sequencing challenge the ethical framework of human genetics research
    Holly K Tabor
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Am J Med Genet A 155:2916-24. 2011
    ..We provide broad guidance about interim ways to contend with these issues and make broad recommendations for areas for novel resource and policy development...
  11. ncbi request reprint Candidate-gene approaches for studying complex genetic traits: practical considerations
    Holly K Tabor
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California 94305 5120, USA
    Nat Rev Genet 3:391-7. 2002
    ..We believe that these criticisms can be usefully countered with an appeal to the principles of epidemiological investigation...
  12. ncbi request reprint Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families
    Jun Li
    Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
    Am J Med Genet 114:24-30. 2002
    ..None of these subsets revealed significant deviation from the null expectation. Our interpretation of these findings is that it is unlikely that HoxA1 and HoxB1 play a significant role in the genetic predisposition to autism...

Research Grants2