THOMAS C contact SUDHOF

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Neurotransmitter release: the last millisecond in the life of a synaptic vesicle
    Thomas C Sudhof
    Department of Molecular and Cellular Physiology, and Howard Hughes Medical Institute, Lorry Lokey SIM1 Building, 265 Campus Drive, Stanford University School of Medicine, Stanford, CA 94305, USA Electronic address
    Neuron 80:675-90. 2013
  2. pmc The presynaptic active zone
    Thomas C Sudhof
    Department of Molecular and Cellular Physiology, and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94304 5453, USA
    Neuron 75:11-25. 2012
  3. pmc Calcium control of neurotransmitter release
    Thomas C Sudhof
    Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
    Cold Spring Harb Perspect Biol 4:a011353. 2012
  4. pmc Neuroligins and neurexins link synaptic function to cognitive disease
    Thomas C Sudhof
    Neuroscience Institute, Department of Molecular and Cellular Physiology, Stanford University, 1050 Arastradero Road B249, Palo Alto, California 94304, USA
    Nature 455:903-11. 2008
  5. pmc Membrane fusion: grappling with SNARE and SM proteins
    Thomas C Sudhof
    Department of Cellular and Molecular Physiology, Stanford University, Palo Alto, CA 94304, USA
    Science 323:474-7. 2009

Research Grants

Detail Information

Publications5

  1. pmc Neurotransmitter release: the last millisecond in the life of a synaptic vesicle
    Thomas C Sudhof
    Department of Molecular and Cellular Physiology, and Howard Hughes Medical Institute, Lorry Lokey SIM1 Building, 265 Campus Drive, Stanford University School of Medicine, Stanford, CA 94305, USA Electronic address
    Neuron 80:675-90. 2013
    ..This architecture allows direct flow of Ca(2+) ions from Ca(2+) channels to synaptotagmin, which then triggers fusion, thus mediating tight millisecond coupling of an action potential to neurotransmitter release. ..
  2. pmc The presynaptic active zone
    Thomas C Sudhof
    Department of Molecular and Cellular Physiology, and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94304 5453, USA
    Neuron 75:11-25. 2012
    ..Moreover, this complex mediates short- and long-term plasticity in response to bursts of action potentials, thus critically contributing to the computational power of a synapse...
  3. pmc Calcium control of neurotransmitter release
    Thomas C Sudhof
    Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
    Cold Spring Harb Perspect Biol 4:a011353. 2012
    ....
  4. pmc Neuroligins and neurexins link synaptic function to cognitive disease
    Thomas C Sudhof
    Neuroscience Institute, Department of Molecular and Cellular Physiology, Stanford University, 1050 Arastradero Road B249, Palo Alto, California 94304, USA
    Nature 455:903-11. 2008
    ..In humans, alterations in genes encoding neurexins or neuroligins have recently been implicated in autism and other cognitive diseases, linking synaptic cell adhesion to cognition and its disorders...
  5. pmc Membrane fusion: grappling with SNARE and SM proteins
    Thomas C Sudhof
    Department of Cellular and Molecular Physiology, Stanford University, Palo Alto, CA 94304, USA
    Science 323:474-7. 2009
    ....

Research Grants13

  1. APP, Alzheimer's Disease, and Synaptic Function
    THOMAS SUDHOF; Fiscal Year: 2007
    ..Together these studies will contribute to our understanding of APP function and Abeta toxicity in AD, and may suggest new avenues for interfering with the pathogenesis of AD. ..
  2. SYNUCLEIN FUNCTIONS: ROLE IN PARKINSON'S DISEASE
    THOMAS SUDHOF; Fiscal Year: 2003
    ..We anticipate that these experiments will establish a molecular understanding of synuclein functions in the brain and provide insight into the role of an alpha synuclein in Parkinson's disease. ..
  3. A systematic test of the relation of ASD heterogeneity to synaptic function
    THOMAS C contact SUDHOF; Fiscal Year: 2010
    ..This project will address these issues by studying the changes in neuron-to-neuron communication caused by the genes associated with autism. ..