G Spivak

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. ncbi request reprint The complex choreography of transcription-coupled repair
    Graciela Spivak
    Biology Department, Stanford University, 385 Serra Mall, Stanford, CA 94305 5020, USA Electronic address
    DNA Repair (Amst) 19:64-70. 2014
  2. pmc Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells
    Jia Guo
    Department of Biology, Stanford University, 371 Serra Mall, Stanford, CA 94305 5020, USA
    Nucleic Acids Res 41:7700-12. 2013
  3. doi request reprint The Comet-FISH assay for the analysis of DNA damage and repair
    Graciela Spivak
    Department of Biology, Stanford University, Stanford, CA, USA
    Methods Mol Biol 659:129-45. 2010
  4. pmc New applications of the Comet assay: Comet-FISH and transcription-coupled DNA repair
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Mutat Res 681:44-50. 2009
  5. ncbi request reprint Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    DNA Repair (Amst) 1:629-43. 2002
  6. ncbi request reprint Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    DNA Repair (Amst) 5:13-22. 2006
  7. ncbi request reprint UV-sensitive syndrome
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Mutat Res 577:162-9. 2005
  8. pmc The many faces of Cockayne syndrome
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Proc Natl Acad Sci U S A 101:15273-4. 2004
  9. ncbi request reprint Workshop on DNA repair and related DNA transactions, a conference report
    G Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    DNA Repair (Amst) 2:235-42. 2003
  10. doi request reprint Transcription-coupled DNA repair: two decades of progress and surprises
    Philip C Hanawalt
    Department of Biology, Stanford University, 371 Serra Mall, Stanford, California 94305 5020, USA
    Nat Rev Mol Cell Biol 9:958-70. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint The complex choreography of transcription-coupled repair
    Graciela Spivak
    Biology Department, Stanford University, 385 Serra Mall, Stanford, CA 94305 5020, USA Electronic address
    DNA Repair (Amst) 19:64-70. 2014
    ..We will discuss general models for the biochemical pathways and how and when cells might choose to utilize TCR or other pathways for repair or bypass of transcription-blocking DNA alterations. ..
  2. pmc Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells
    Jia Guo
    Department of Biology, Stanford University, 371 Serra Mall, Stanford, CA 94305 5020, USA
    Nucleic Acids Res 41:7700-12. 2013
    ..We have also demonstrated that the hOGG1, XPA, CSB and UVSSA proteins, as well as actively elongating RNA polymerase II, are required for this process, suggesting cross-talk between DNA repair pathways...
  3. doi request reprint The Comet-FISH assay for the analysis of DNA damage and repair
    Graciela Spivak
    Department of Biology, Stanford University, Stanford, CA, USA
    Methods Mol Biol 659:129-45. 2010
    ..The unique advantages and limitations of the method for particular applications are discussed...
  4. pmc New applications of the Comet assay: Comet-FISH and transcription-coupled DNA repair
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Mutat Res 681:44-50. 2009
    ..We review the existing evidence and discuss the implications in relation to current models for the molecular mechanism of TCR...
  5. ncbi request reprint Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    DNA Repair (Amst) 1:629-43. 2002
    ....
  6. ncbi request reprint Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    DNA Repair (Amst) 5:13-22. 2006
    ..Repair of thymine glycols in the lacZ gene was measured in plasmids extracted from transfected cells; removal of the lesions is efficient and without strand bias in all the cell lines tested...
  7. ncbi request reprint UV-sensitive syndrome
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Mutat Res 577:162-9. 2005
    ..In this review, I will summarize the current understanding of the UV-sensitive syndrome and compare it with the Cockayne syndrome...
  8. pmc The many faces of Cockayne syndrome
    Graciela Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    Proc Natl Acad Sci U S A 101:15273-4. 2004
  9. ncbi request reprint Workshop on DNA repair and related DNA transactions, a conference report
    G Spivak
    Department of Biological Sciences, Stanford University, Stanford, CA 94305 5020, USA
    DNA Repair (Amst) 2:235-42. 2003
  10. doi request reprint Transcription-coupled DNA repair: two decades of progress and surprises
    Philip C Hanawalt
    Department of Biology, Stanford University, 371 Serra Mall, Stanford, California 94305 5020, USA
    Nat Rev Mol Cell Biol 9:958-70. 2008
    ..Futile cycles of TCR at naturally occurring non-canonical DNA structures might contribute to genomic instability and genetic disease...
  11. ncbi request reprint In vivo assays for transcription-coupled repair
    Graciela Spivak
    Department of Biological Sciences, Stanford University, California, USA
    Methods Enzymol 408:223-46. 2006
    ..Both methods have unique advantages and limitations for particular applications...
  12. ncbi request reprint Nucleotide excision repair activity varies among murine spermatogenic cell types
    Guogang Xu
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, 78229, USA
    Biol Reprod 73:123-30. 2005
    ..Overall, the data suggest cell type-specific NER activity during murine spermatogenesis, and our results have possible implications for germ cell aging...