Research Topics
| David A SpiegelSummaryAffiliation: Stanford University Country: USA Publications
Research Grants
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Detail Information
Publications
Tranceformations: hypnosis in brain and bodyDavid Spiegel
Stanford University School of Medicine, Stanford, CA 94305 5718, USA
Depress Anxiety 30:342-52. 2013..The evidence indicates an important role for hypnosis in managing anxiety disorders and anxiety related to medical illness...- Dissociative disorders in DSM-5David Spiegel
Department of Psychiatry, School of Medicine, Stanford University, Stanford, California 94304 5718, USA
Annu Rev Clin Psychol 9:299-326. 2013..Conversion disorder (functional neurological symptom disorder) will likely remain with the somatic symptom disorders, despite considerable dissociative comorbidity... 
Mind matters in cancer survivalDavid Spiegel
Stanford University School of Medicine, Stanford, CA 94305, USA
Psychooncology 21:588-93. 2012..The very name "psycho-oncology" implies interaction between brain and body. One of the most intriguing scientific questions for the field is whether or not living better may also mean living longer...
Effects of psychotherapy on cancer survivalDavid Spiegel
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, California 94305 5718, USA
Nat Rev Cancer 2:383-9. 2002..Does emotional support affect the course of cancer? What physiological pathways might mediate such an effect? Given what we now know, should we change the standard of care for cancer patients?..- Effects of supportive-expressive group therapy on survival of patients with metastatic breast cancer: a randomized prospective trialDavid Spiegel
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5718, USA
Cancer 110:1130-8. 2007..Subsequent findings concerning the question of whether such psychosocial support affects survival have been mixed... - Stress sensitivity in metastatic breast cancer: analysis of hypothalamic-pituitary-adrenal axis functionDavid Spiegel
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5718, USA
Psychoneuroendocrinology 31:1231-44. 2006..21, p=.04, N=95). Our general findings suggest that flatter daytime cortisol slopes among metastatic breast cancer patients may be related to disrupted feedback inhibition rather than hypersensitivity in response to stimulation... - Dissociative disorders in DSM-5David Spiegel
Department of Psychiatry, Stanford University, Palo Alto, California, USA
Depress Anxiety 28:824-52. 2011..The periodic revision of the DSM provides an opportunity to revisit the assumptions underlying specific diagnoses and the empirical support, or lack of it, for the defining diagnostic criteria... - Dissociative disorders in DSM-5David Spiegel
Department of Psychiatry, Stanford University, Palo Alto, California, USA
Depress Anxiety 28:E17-45. 2011..The periodic revision of the DSM provides an opportunity to revisit the assumptions underlying specific diagnoses and the empirical support, or lack of it, for the defining diagnostic criteria... - Effects of supportive-expressive group therapy on pain in women with metastatic breast cancerLisa D Butler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, USA
Health Psychol 28:579-87. 2009..To examine whether a group intervention including hypnosis can reduce cancer pain and trait hypnotizability would moderate these effects... - Sleep disturbances in women with metastatic breast cancerCheryl Koopman
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
Breast J 8:362-70. 2002..These results suggest that women with metastatic breast cancer who are at higher risk for having sleeping problems are those who are less educated, in pain, depressed, have bony metastases, or lack social support... - Circadian affective, cardiopulmonary, and cortisol variability in depressed and nondepressed individuals at risk for cardiovascular diseaseAnsgar Conrad
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
J Psychiatr Res 42:769-77. 2008..Diurnal mood variations of older individuals at risk for CVD differ from those reported for other groups and daily fluctuations in NA are not related to cardiac autonomic control in depressed individuals... - Living in the face of death: interviews with 12 terminally ill women on home hospice careMareile M Grumann
The Psychosocial Treatment Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
Palliat Support Care 1:23-32. 2003..To determine how home hospice patients deal with their impending death and whether there is a need for greater involvement of mental health professionals in the care of patients dying at home... - Mood disturbance in community cancer support groups. The role of emotional suppression and fighting spiritMatthew J Cordova
Stanford University School of Medicine, Stanford, CA, USA
J Psychosom Res 55:461-7. 2003.... - Disengagement and social support moderate distress among women with a family history of breast cancerJulie M Turner-Cobb
Psychiatry and Behavioral Sciences and Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA
Breast J 12:7-15. 2006.... - The effect of peer counseling on quality of life following diagnosis of breast cancer: an observational studyJanine Giese-Davis
Department of Psychiatry and Behavioral Sciences, Stanford University, CA, USA
Psychooncology 15:1014-22. 2006..Randomized clinical trials are needed to demonstrate the efficacy of peer navigator programs... - Sexual violence, posttraumatic stress disorder, and the pelvic examination: how do beliefs about the safety, necessity, and utility of the examination influence patient experiences?Julie C Weitlauf
Center for Health Care Evaluation, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94025, USA
J Womens Health (Larchmt) 19:1271-80. 2010..Efforts to more fully characterize these reactions and identify core factors (i.e., beliefs about the examination) that may influence these reactions are warranted... - Emotional expression and diurnal cortisol slope in women with metastatic breast cancer in supportive-expressive group therapy: a preliminary studyJanine Giese-Davis
Stanford University, Department of Psychiatry and Behavioral Sciences, Stanford, CA 94305 5718, USA
Biol Psychol 73:190-8. 2006.... - Psychophysiological and cortisol responses to psychological stress in depressed and nondepressed older men and women with elevated cardiovascular disease riskC Barr Taylor
Department of Medicine, Stanford University School of Medicine, Stanford, California 94305 5722, USA
Psychosom Med 68:538-46. 2006..The objective of this study was to compare psychophysiological and cortisol reactions to psychological stress in older depressed and nondepressed patients at risk for cardiovascular disease (CVD)... - Effects of quality of life and coping on depression among adults living with HIV/AIDSCheryl Gore-Felton
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
J Health Psychol 11:711-29. 2006.... - Depression and stress reactivity in metastatic breast cancerJanine Giese-Davis
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
Psychosom Med 68:675-83. 2006..This study investigated how depression affects MBC stress reactivity, including autonomic (ANS) and hypothalamic-pituitary-adrenal (HPA) axis function... - Hypnotizability, posttraumatic stress, and depressive symptoms in metastatic breast cancerAlex S Keuroghlian
Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5718, USA
Int J Clin Exp Hypn 58:39-52. 2010..The authors relate these results to findings in other clinical populations and discuss implications for the psychosocial treatment of metastatic breast cancer... - Regional brain activation during verbal declarative memory in metastatic breast cancerShelli R Kesler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5795, USA
Clin Cancer Res 15:6665-73. 2009..We attempted to determine if verbal memory impairments were related to the most commonly studied disease parameters including adjuvant chemotherapy and chronic stress-related disruption of limbic system structures... - Commentary: Reversing amnesia about hypnosisDavid Spiegel
Stanford University School of Medicine, USA
Am J Clin Hypn 49:181-2. 2007 - Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk?C Barr Taylor
Department of Psychiatry and Behavioral Sciences, Stanford Medical Center, 401 Quarry Rd, Room 1316, Stanford, CA 94305 5722, USA
J Psychiatr Res 43:1246-52. 2009..The normal controls exhibited no change in the variables measured during the same time. A significant improvement in mood may have little impact on most traditional or atypical risk factors, cortisol or cardiophysiology... - Meditation with yoga, group therapy with hypnosis, and psychoeducation for long-term depressed mood: a randomized pilot trialLisa D Butler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 571, USA
J Clin Psychol 64:806-20. 2008..Although all groups reported some reduction in symptom levels, they did not differ significantly in that outcome. Overall, these results suggest that these two interventions show promise for treating low- to moderate-level depression... - Social support and maladaptive coping as predictors of the change in physical health symptoms among persons living with HIV/AIDSEric Ashton
Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences, Stanford, California 94305-5718, USA
AIDS Patient Care STDS 19:587-98. 2005..These findings provide further evidence that social support can buffer deleterious health outcomes among individuals with a chronic illness. Future research needs to examine mediating pathways that can explain this relationship... - Acute stress reactions to recent life events among women and men living with HIV/AIDSCheryl Koopman
Department of Psychiatry and Behavioral Sciences, Stanford University, California 94305 5718, USA
Int J Psychiatry Med 32:361-78. 2002..A second aim was to investigate the relationship of acute stress reactions among HIV-infected men and women to posttraumatic stress disorder (PTSD) symptoms to previous traumatic life events... - Psychological distress and pain significantly increase before death in metastatic breast cancer patientsLisa D Butler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5718, USA
Psychosom Med 65:416-26. 2003..It was hypothesized that psychological distress would increase significantly before death independent of changes in pain... - Acute stress reactions following the assassination of Mexican presidential candidate ColosioJose R Maldonado
Department of Psychiatry and Behavioral Sciences, Stanford University, California 94305 5718, USA
J Trauma Stress 15:401-5. 2002.... - HIV: effectiveness of complementary and alternative medicineRachel Power
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Rd, Stanford, CA 94305 5718, USA
Prim Care 29:361-78. 2002.... - Mesmer minus magic: hypnosis and modern medicineDavid Spiegel
Stanford University School of Medicine, California 94305 5718, USA
Int J Clin Exp Hypn 50:397-406. 2002..Both hypnosis and medicine ultimately benefited... - Comorbidity of depression with other medical diseases in the elderlyK Ranga R Krishnan
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 52:559-88. 2002..This review focuses exclusively on unipolar disorder. The review summarizes the current state of the art and also makes recommendations for future directions... - Psychosocial intervention for lesbians with primary breast cancerPat Fobair
Department of Radiation Oncology, Stanford Hospital and Clinics, Stanford University, Stanford, CA 94305 5718, USA
Psychooncology 11:427-38. 2002..There were no changes in body image, sexuality, or attitudes toward health-care providers. These results suggest that Supportive/Expressive group intervention appears to be helpful for lesbians with breast cancer... - Traumatic stress symptoms among women with recently diagnosed primary breast cancerCheryl Koopman
Department of Psychiatry and Behavioral Sciences, Stanford University, California 94305 5718, USA
J Trauma Stress 15:277-87. 2002..Furthermore, these results suggest women at greatest risk are those who are younger, who receive postsurgical cancer treatment, who are low in emotional self-efficacy and whose lives are most affected by having cancer... - Change in emotion-regulation strategy for women with metastatic breast cancer following supportive-expressive group therapyJanine Giese-Davis
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, California 94305 5718, USA
J Consult Clin Psychol 70:916-25. 2002..Even though these aspects of emotion-regulation appear trait-like within the control group, significant change was observed with treatment... - Social support, substance use, and denial in relationship to antiretroviral treatment adherence among HIV-infected personsRachel Power
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94305 5718, USA
AIDS Patient Care STDS 17:245-52. 2003..Furthermore, couple-based approaches enlisting partner support may help persons living with HIV to adhere to antiretroviral regimens... - Anticipating loss and other temporal stressors predict traumatic stress symptoms among partners of metastatic/recurrent breast cancer patientsLisa D Butler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Room 2320, Stanford, CA 94305 5718, USA
Psychooncology 14:492-502. 2005..Limitations and treatment implications of the present research and directions for future research are discussed... - Negative and positive visual hypnotic hallucinations: attending inside and outDavid Spiegel
Stanford University School of Medicine, Stanford, California 94305 5718, USA
Int J Clin Exp Hypn 51:130-46. 2003..Positive obstructive hallucinations seem to allow for a hypnotic focus inward, activating the functioning of attentional neural systems and reducing perceptual ones... - Treatment of acute traumatic stress reactionsDavid Spiegel
Stanford University, Stanford, CA 94305 5718, USA
J Trauma Dissociation 6:101-8. 2005.... - Cancer supportive care, improving the quality of life for cancer patients. A program evaluation reportErnest Rosenbaum
Stanford Cancer Supportive Care Program, Stanford Hospital and Clinics, 1101 Welch Road, Bldg A, Ste 6, Stanford, CA 94305, USA
Support Care Cancer 12:293-301. 2004..The Stanford Cancer Supportive Care Program was initiated in 1999 to provide support for cancer patients, addressing the need for improved physical and emotional well-being and quality of life. This paper is a program evaluation report... - Hypnosis reduces distress and duration of an invasive medical procedure for childrenLisa D Butler
Department of Psychiatry, Stanford University School of Medicine, Stanford, CA 94305 5718, USA
Pediatrics 115:e77-85. 2005..This study was designed to examine whether relaxation and analgesia facilitated with hypnosis could reduce distress and procedure time for children who undergo this procedure... - Repression and high anxiety are associated with aberrant diurnal cortisol rhythms in women with metastatic breast cancerJanine Giese-Davis
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305 5718, USA
Health Psychol 23:645-50. 2004..Diurnal slope was similar for repressers and high-anxious groups. Groups did not differ on mean cortisol levels, nor did they differ on intercept (morning) values... - Coping, social support, and attachment style as psychosocial correlates of adjustment in men and women with HIV/AIDSJulie M Turner-Cobb
Stanford University, Stanford, California, USA
J Behav Med 25:337-53. 2002..Implications for physical health outcome and opportunities for intervention are discussed... - Design decisions to optimize reliability of daytime cortisol slopes in an older populationHelena C Kraemer
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Am J Geriatr Psychiatry 14:325-33. 2006..Unnecessarily imposing a burdensome protocol has both ethical and scientific ramifications and should be carefully avoided... - Depression and cancer: mechanisms and disease progressionDavid Spiegel
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
Biol Psychiatry 54:269-82. 2003..Depression also affects components of immune function that may affect cancer surveillance. Thus, there is evidence of a bidirectional relationship between cancer and depression, offering new opportunities for therapeutic intervention... - The interaction of social network size and stressful life events predict delayed-type hypersensitivity among women with metastatic breast cancerJulie M Turner-Cobb
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
Int J Psychophysiol 54:241-9. 2004..The relationship between social network size and immune response in women with metastatic breast cancer depends on prior stressful life experience... - Circadian disruption in cancer: a neuroendocrine-immune pathway from stress to disease?Sandra Sephton
James Graham Brown Cancer Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, 500 South Preston Street, Room 210, Louisville, KY 40202, USA
Brain Behav Immun 17:321-8. 2003..Thus, stress-related circadian disruption may have negative implications for cancer prognosis. Psychosocial effects on cancer progression may be measured, and possibly mediated, by disruption of circadian function... - Use and misuse of the consolidated standards of reporting trials (CONSORT) guidelines to assess research findings: comment on Coyne, Stefanek, and Palmer (2007)Helena C Kraemer
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5718, USA
Psychol Bull 135:173-8; discussion 179-82. 2009..to recommend stopping research in an area that may be highly productive. Recent developments in the field are summarized. It is a mistaken and dangerous conclusion to declare this or other areas of scientific research off limits... - Psychosocial predictors of resilience after the September 11, 2001 terrorist attacksLisa D Butler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
J Nerv Ment Dis 197:266-73. 2009..These findings highlight the role of emotional, coping, social support, and particularly, cognitive variables in adjustment after terrorism... - Concerns about sexuality after breast cancerPatricia Fobair
Supportive Care Program, Stanford Hospital Cancer Center, Stanford, CA, USA
Cancer J 15:19-26. 2009..Other solutions include effective psychologic and emotional counseling and pharmaceutical and over the counter assistance for hot flashes, vaginal dryness, and pain to assist with the physiological issues...
Research Grants
- EFFECTS OF PSYCHOLOGICAL TREATMENT ON CANCER SURVIVALDavid Spiegel; Fiscal Year: 1993..These studies will determine whether psychosocial support should be added to the standard treatment regimen because of proven medical as well as psychological benefit...
- PSYCHOSOCIAL TREATMENT EFFECTS ON CANCER SURVIVALDavid Spiegel; Fiscal Year: 2004..The recruitment of this diverse sample of patients will also increase generalizability of findings regarding group psychotherapy outcome and its predictors. ..
- GROUP INTERVENTIONS TO PREVENT HIV IN HIGH RISK WOMENDavid Spiegel; Fiscal Year: 2003..We will examine three mediators of treatment effectiveness, including: 1) trauma reactive and resilient beliefs about self and the world; 2) differentiation and integration of self; and 3) interpersonal relations. ..
- Sleep, Circadian, Hormonal Dysregulation, and Breast Cancer SurvivalDavid Spiegel; Fiscal Year: 2007..We will relate these measures to the subsequent course of breast cancer progression. Results of this study will provide specific evidence regarding how improved sleep management may affect the course of breast cancer. ..
- Stress, the HPA and Health in AgingDavid Spiegel; Fiscal Year: 2007..abstract_text> ..
- PSYCHOSOCIAL TREATMENT EFFECTS ON CANCER SURVIVALDavid Spiegel; Fiscal Year: 1999....
- Sleep, Circadian, Hormonal Dysregulation, and Breast Cancer SurvivalDavid Spiegel; Fiscal Year: 2010..We will relate these measures to the subsequent course of breast cancer progression. Results of this study will provide specific evidence regarding how improved sleep management may affect the course of breast cancer. ..