Shawn F Sorrells

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc An inflammatory review of glucocorticoid actions in the CNS
    Shawn F Sorrells
    Department of Biological Sciences, Stanford University, Gilbert Lab MC 5020, Stanford, CA 94305 5020, USA
    Brain Behav Immun 21:259-72. 2007
  2. doi request reprint The stressed CNS: when glucocorticoids aggravate inflammation
    Shawn F Sorrells
    Department of Biological Sciences, Stanford University, Gilbert Lab MC 5020, Stanford, CA 94305 5020, USA
    Neuron 64:33-9. 2009
  3. pmc Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation
    Shawn F Sorrells
    Department of Biology, Stanford University, Stanford, California 94305 5020, USA
    J Neurosci 33:7877-89. 2013
  4. doi request reprint Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner
    Carolina Demarchi Munhoz
    Department of Biological Sciences, Stanford University, Stanford, California 94305 5020, USA
    J Neurosci 30:13690-8. 2010
  5. pmc Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat
    Nathan C Manley
    Department of Biology, Stanford University, Stanford, California, United States of America
    PLoS ONE 8:e61789. 2013

Detail Information

Publications5

  1. pmc An inflammatory review of glucocorticoid actions in the CNS
    Shawn F Sorrells
    Department of Biological Sciences, Stanford University, Gilbert Lab MC 5020, Stanford, CA 94305 5020, USA
    Brain Behav Immun 21:259-72. 2007
    ..We consider how these unexpected effects of glucocorticoids can co-exist with their well-established anti-inflammatory properties, as well as the considerable clinical implications of these findings...
  2. doi request reprint The stressed CNS: when glucocorticoids aggravate inflammation
    Shawn F Sorrells
    Department of Biological Sciences, Stanford University, Gilbert Lab MC 5020, Stanford, CA 94305 5020, USA
    Neuron 64:33-9. 2009
    ..In this minireview we discuss the contexts wherein GCs increase CNS inflammation and point out directions for future investigation...
  3. pmc Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation
    Shawn F Sorrells
    Department of Biology, Stanford University, Stanford, California 94305 5020, USA
    J Neurosci 33:7877-89. 2013
    ..Finally, GCs compromised neuron survival, an effect mediated by GR in myeloid and endothelial cells to a greater extent than by neuronal GR...
  4. doi request reprint Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner
    Carolina Demarchi Munhoz
    Department of Biological Sciences, Stanford University, Stanford, California 94305 5020, USA
    J Neurosci 30:13690-8. 2010
    ..These findings suggest that GCs do not uniformly suppress neuroinflammation and can even enhance it at multiple levels in the pathway linking LPS exposure to inflammation...
  5. pmc Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat
    Nathan C Manley
    Department of Biology, Stanford University, Stanford, California, United States of America
    PLoS ONE 8:e61789. 2013
    ..These results demonstrate a non-invasive method to target ischemic brain injury and may ultimately provide a way to selectively deliver therapeutic compounds to the injured brain...