R L Smith

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint Effects of intermittent hydrostatic pressure and BMP-2 on osteoarthritic human chondrocyte metabolism in vitro
    R L Smith
    Bone and Joint RR and D Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA
    J Orthop Res 29:361-8. 2011
  2. ncbi request reprint Degradative enzymes in osteoarthritis
    R L Smith
    Stanford University School of Medicine, Department of Functional Restoration, Stanford, California 94305 5341, USA
    Front Biosci 4:D704-12. 1999
  3. ncbi request reprint G-protein activity requirement for polymethylmethacrylate and titanium particle-induced fibroblast interleukin-6 and monocyte chemoattractant protein-1 release in vitro
    M C Trindade
    Orthopaedic Research Laboratory, Stanford University School of Medicine, Stanford, California 94305, USA
    J Biomed Mater Res 51:360-8. 2000
  4. ncbi request reprint Effects of local infusion of TGFbeta on bone ingrowth in rabbit chambers
    S Goodman
    Division of Orthopaedic Surgery, Stanford University Medical Center, Stanford, CA 94305, USA
    J Biomed Mater Res 53:475-9. 2000
  5. ncbi request reprint The effects of titanium and polymethylmethacrylate particles on osteoblast phenotypic stability
    R Ramachandran
    Department of Orthopedic Surgery, Stanford University, California, USA
    J Biomed Mater Res A 77:512-7. 2006
  6. ncbi request reprint Comparison of VEGF-producing cells in periprosthetic osteolysis
    J P Spanogle
    Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Biomaterials 27:3882-7. 2006
  7. ncbi request reprint Effects of a p38 MAP kinase inhibitor on bone ingrowth and tissue differentiation in rabbit chambers
    S B Goodman
    Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA
    J Biomed Mater Res A 81:310-6. 2007
  8. doi request reprint Efficacy of a p38 mitogen activated protein kinase inhibitor in mitigating an established inflammatory reaction to polyethylene particles in vivo
    T Ma
    Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA
    J Biomed Mater Res A 89:117-23. 2009
  9. pmc An in vivo murine model of continuous intramedullary infusion of polyethylene particles
    Ting Ma
    Department of Orthopaedic Surgery, Stanford University, School of Medicine, Stanford, CA, USA
    Biomaterials 29:3738-42. 2008
  10. pmc Prediction of glycosaminoglycan content in human cartilage by age, T1ρ and T2 MRI
    K E Keenan
    Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
    Osteoarthritis Cartilage 19:171-9. 2011

Detail Information

Publications11

  1. doi request reprint Effects of intermittent hydrostatic pressure and BMP-2 on osteoarthritic human chondrocyte metabolism in vitro
    R L Smith
    Bone and Joint RR and D Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA
    J Orthop Res 29:361-8. 2011
    ....
  2. ncbi request reprint Degradative enzymes in osteoarthritis
    R L Smith
    Stanford University School of Medicine, Department of Functional Restoration, Stanford, California 94305 5341, USA
    Front Biosci 4:D704-12. 1999
    ....
  3. ncbi request reprint G-protein activity requirement for polymethylmethacrylate and titanium particle-induced fibroblast interleukin-6 and monocyte chemoattractant protein-1 release in vitro
    M C Trindade
    Orthopaedic Research Laboratory, Stanford University School of Medicine, Stanford, California 94305, USA
    J Biomed Mater Res 51:360-8. 2000
    ..c) 2000 John Wiley & Sons, Inc...
  4. ncbi request reprint Effects of local infusion of TGFbeta on bone ingrowth in rabbit chambers
    S Goodman
    Division of Orthopaedic Surgery, Stanford University Medical Center, Stanford, CA 94305, USA
    J Biomed Mater Res 53:475-9. 2000
    ..In an "unperturbed" bone ingrowth system (i.e., if bone ingrowth is not initially suppressed by other stimuli), this dose of TGFbeta did not enhance bone ingrowth using the DTC model...
  5. ncbi request reprint The effects of titanium and polymethylmethacrylate particles on osteoblast phenotypic stability
    R Ramachandran
    Department of Orthopedic Surgery, Stanford University, California, USA
    J Biomed Mater Res A 77:512-7. 2006
    ..The data show that titanium but not PMMA particles shifts bone cell metabolism to preferentially produce fibrous tissue rather than bone...
  6. ncbi request reprint Comparison of VEGF-producing cells in periprosthetic osteolysis
    J P Spanogle
    Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Biomaterials 27:3882-7. 2006
    ..At the bone-implant interface, we found increased numbers of macrophages-cellular mediators of OL-and increased VEGF expression. VEGF may be a possible target for therapeutic intervention in mitigating OL...
  7. ncbi request reprint Effects of a p38 MAP kinase inhibitor on bone ingrowth and tissue differentiation in rabbit chambers
    S B Goodman
    Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA
    J Biomed Mater Res A 81:310-6. 2007
    ..Additional experiments are needed to establish the efficacy of p38 MAPK inhibitor administration on mitigating an established inflammatory and foreign body reaction that parallels the clinical situation more closely...
  8. doi request reprint Efficacy of a p38 mitogen activated protein kinase inhibitor in mitigating an established inflammatory reaction to polyethylene particles in vivo
    T Ma
    Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA
    J Biomed Mater Res A 89:117-23. 2009
    ..Using the present model, the oral p38 MAPK inhibitor was ineffective in improving bone ingrowth in the presence of polyethylene particles...
  9. pmc An in vivo murine model of continuous intramedullary infusion of polyethylene particles
    Ting Ma
    Department of Orthopaedic Surgery, Stanford University, School of Medicine, Stanford, CA, USA
    Biomaterials 29:3738-42. 2008
    ....
  10. pmc Prediction of glycosaminoglycan content in human cartilage by age, T1ρ and T2 MRI
    K E Keenan
    Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
    Osteoarthritis Cartilage 19:171-9. 2011
    ..We hypothesized that T1ρ relaxation time would be associated with GAG content in human cartilage with normal T2 relaxation times...
  11. ncbi request reprint Effects of local infusion of OP-1 on particle-induced and NSAID-induced inhibition of bone ingrowth in vivo
    T Ma
    Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA
    J Biomed Mater Res A 79:740-6. 2006
    ..05). These findings underline a potential role for local treatment with OP-1 to increase bone formation in the presence of potentially adverse stimuli such as polyethylene wear particles or NSAID use...