Research Topics
| Gurkirpal SinghSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I StudyGurkirpal Singh
Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, Calif 94301, USA
Am J Med 119:255-66. 2006..To evaluate the efficacy and upper gastrointestinal (UGI) safety of celecoxib, compared with nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), among patients with osteoarthritis...- Arthritis, Rheumatism and Aging Medical Information System Post-Marketing Surveillance ProgramG Singh
Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA
J Rheumatol 28:1174-9. 2001..The ARAMIS-PMS program aims to study patients in normal clinical setting to evaluate the real-life effectiveness, toxicity, and cost effectiveness of various medications used to treat rheumatic diseases... - Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicamGurkirpal Singh
Divisions of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
Am J Med 117:100-6. 2004..To assess the risk of serious gastrointestinal and thromboembolic complications with approved doses of meloxicam... 
Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysisGurkirpal Singh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 100 Hamilton Avenue, Suite 225 42, Palo Alto, CA 94301, USA
Arthritis Res Ther 8:R153. 2006..Nonselective NSAIDs are frequently prescribed, and so further investigation into the risk of AMI is warranted because the potential for harm can be substantial...- Appropriate choice of proton pump inhibitor therapy in the prevention and management of NSAID-related gastrointestinal damageG Singh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94062, USA
Int J Clin Pract 59:1210-7. 2005..PPIs have an excellent safety profile, and pantoprazole--with its low potential for drug-drug interactions--is particularly suitable for administration to elderly patients who often require concomitant treatment with other medications... 
Effects of long-term corticosteroid usage on functional disability in patients with early rheumatoid arthritis, regardless of controlled disease activityEiichi Tanaka
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA
Rheumatol Int 32:749-57. 2012..05). Frequent steroid usage was associated with significantly higher final J-HAQ scores in early RA patients, even though their disease was managed efficiently by maintaining the DAS28 values under 3.2 over a long-term period...- Proximal and distal colorectal cancer resection rates in the United States since widespread screening by colonoscopyParvathi A Myer
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94063, USA
Gastroenterology 143:1227-36. 2012..We examined US trends in rates of resection for proximal vs distal CRC, which reflect CRC incidence, in the context of national CRC screening data, before and since Medicare's 2001 decision to pay for screening colonoscopy... - Understanding NSAID-PPI-COX-2 interrelationshipsGurkirpal Singh
Stanford University, Palo Alto, California, USA
Drugs Today (Barc) 40:21-4. 2004..Finally, the combination of a COX-2 inhibitor with a PPI has shown promise in patients with previous NSAID-related gastrointestinal complications who are at high risk for reinjury... - Medical care costs of patients with rheumatoid arthritis during the prebiologics period in Japan: a large prospective observational cohort studyEiichi Tanaka
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA
Mod Rheumatol 20:46-53. 2010..001). Outpatient costs for patients with RA increased year after year over the 4-year period under observation in Japan. Medical costs were higher with increasing RA disease activity and disability levels... - Proton pump inhibitors for gastroduodenal damage related to nonsteroidal anti-inflammatory drugs or aspirin: twelve important questions for clinical practiceGaurav Arora
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305 5187, USA
Clin Gastroenterol Hepatol 7:725-35. 2009..We then summarized our recommendations on the use of PPIs for the clinical management of patients using NSAIDs or aspirin... - Declines in mortality from acute myocardial infarction in successive incidence and birth cohorts of patients with rheumatoid arthritisEswar Krishnan
Stanford University, Division of Immunology, Department of Medicine, 1000 Welch Rd, Suite 203, Palo Alto, Calif, USA
Circulation 110:1774-9. 2004..The impact of this on atherosclerotic cardiovascular diseases is not known... - Utilization and antiviral therapy in patients with chronic hepatitis C: analysis of ambulatory care visits in the USRamsey Cheung
Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA
Dig Dis Sci 55:1744-51. 2010..Studies on mostly veterans found the majority of chronic hepatitis C (CHC) patients were not treated. Little information exists on a broad-based population... - Treatment options for osteoarthritisGurkirpal Singh
Department of Medicine, Division of Immunology and Rheumatology Stanford University School of Medicine, Palo Alto, California, USA
Surg Technol Int 11:287-92. 2003..The former, however, have not been shown unequivocally to be effective. Future treatment modalities for OA are geared toward reversing the disease process and may include disease-modifying drugs and gene therapy... - Risk of perforation from a colonoscopy in adults: a large population-based studyGaurav Arora
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305 5187, USA
Gastrointest Endosc 69:654-64. 2009..Previous studies that reported the incidence of perforation from a colonoscopy are limited by small sample sizes, restricted age groups, or single-center data... - Use of health care resources and cost of care for adults with constipationGurkirpal Singh
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California, USA
Clin Gastroenterol Hepatol 5:1053-8. 2007..To evaluate the clinical and fiscal effects of constipation, we assessed health care resource use by patients with constipation enrolled in a large state Medicaid program... - Attrition bias in rheumatoid arthritis databanks: a case study of 6346 patients in 11 databanks and 65,649 administrations of the Health Assessment QuestionnaireEswar Krishnan
Division of Rheumatology, Department of Medicine, Stanford University, Palo Alto, California, USA
J Rheumatol 31:1320-6. 2004..Patient dropout (attrition) can bias and threaten validity of databank-based studies. Although there are several databanks of rheumatoid arthritis (RA) in operation, this phenomenon has not been well studied... - Diagnosis, comorbidities, and management of irritable bowel syndrome in patients in a large health maintenance organizationUri Ladabaum
Division of Gastroenterology, Stanford University, Stanford, California, USA
Clin Gastroenterol Hepatol 10:37-45. 2012..We aimed to characterize practice patterns for patients with IBS in a large health maintenance organization, analyzing point of diagnosis, testing, comorbidities, and treatment... - Epidemiology of alcohol-related liver and pancreatic disease in the United StatesAlice L Yang
Department of Medicine, Division of Gastroenterology and Hepatology, Veterans Affairs Palo Alto Health Care System and Stanford University, 3801 Miranda Ave 154J, Palo Alto, CA, USA
Arch Intern Med 168:649-56. 2008..To better understand alcohol-related liver and pancreas effects on and associations with different ethnic groups and sexes, we analyzed the trends of AP, CP, AH, CH, AP plus AH, and CP plus CH in the United States... - Prevalence of cardiovascular disease risk factors among US adults with self-reported osteoarthritis: data from the Third National Health and Nutrition Examination SurveyGurkirpal Singh
ARAIS-PMS Program, Stanford University School of Medicine, Palo Alto, California, USA
Am J Manag Care 8:S383-91. 2002..These findings highlight the need to consider patients' comorbidites when selecting the appropriate treatment options... - Estimating the cost-effectiveness of 54 weeks of infliximab for rheumatoid arthritisJohn B Wong
Division of Clinical Decision Making, Department of Medicine, Tupper Research Institute, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Am J Med 113:400-8. 2002..To estimate the cost-effectiveness of infliximab plus methotrexate for active, refractory rheumatoid arthritis... - The problem with NSAIDs: what data to believe?Gayle McKellar
Center for Rheumatic Diseases, Glasgow Royal Infirmary, Castle Street, Glasgow G4 0SF, UK
Curr Pain Headache Rep 11:423-7. 2007..The US Food and Drug Administration has recommended that both classes of drugs carry a black box warning with regard to gastrointestinal and cardiovascular risks... - Risk of serious NSAID-related gastrointestinal events during long-term exposure: a systematic reviewDelia Schaffer
Pfizer Australia, Sydney, NSW, Australia
Med J Aust 185:501-6. 2006..Exposure to non-steroidal anti-inflammatory drugs (NSAIDs) is associated with increased risk of serious gastrointestinal (GI) events compared with non-exposure. We investigated whether that risk is sustained over time... - Validation of a Japanese version of the Stanford Health Assessment Questionnaire in 3,763 patients with rheumatoid arthritisYuko Matsuda
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan
Arthritis Rheum 49:784-8. 2003..CONCLUSION: The final version of the J-HAQ is a valid and reliable instrument for measuring functional status in Japanese-speaking RA patients... - Powering our way to the elusive side effect: a composite outcome 'basket' of predefined designated endpoints in each organ system should be included in all controlled trialsPeter Tugwell
Institute of Population Health, University of Ottawa, 1 Stewart Street, Room 312, Ottawa, Ontario K1N 6N5, Canada
J Clin Epidemiol 58:785-90. 2005..To review the methodological insights gained from the CLASS and VIGOR coxib trials and make suggestions for primary safety outcomes in future trials... - Update on the use of analgesics versus nonsteroidal anti-inflammatory drugs in rheumatic disorders: risks and benefitsGayle McKellar
Centre for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, UK
Curr Opin Rheumatol 20:239-45. 2008..An evaluation of the potential risks and benefits of other analgesics has also followed. In this time of greater analysis of analgesic use, this review seeks to present the most recent evidence... - Nonsteroidal anti-inflammatory drug use does not affect short-term endoscopic and histologic outcomes after Helicobacter pylori eradication in patients with rheumatoid arthritisEiichi Tanaka
Institute of Rheumatology, Tokyo Women s Medical University, Tokyo 162 0054, Japan
Mod Rheumatol 17:228-34. 2007..5 months, use of NSAIDs in Japanese patients with RA did not impair the healing process of gastric and duodenal ulcers nor did it affect the endoscopic and histological improvements associated with H. pylori eradication... - Consequences of increased systolic blood pressure in patients with osteoarthritis and rheumatoid arthritisGurkirpal Singh
Medical Research International, Waltham, Massachusetts 02451-7341, USA
J Rheumatol 30:714-9. 2003..It is important that clinicians who treat patients with OA/RA accurately weigh the potential risks of these medications against their benefits... - Improvement of disease activity of rheumatoid arthritis patients from 2000 to 2006 in a large observational cohort study IORRA in JapanHisashi Yamanaka
Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada cho, Shinjuku ku, Tokyo, 162 0054, Japan
Mod Rheumatol 17:283-9. 2007..The suppression of disease activity resulted in a better outcome for patients...