Joseph B Shrager

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi Approach to the patient with multiple lung nodules
    Joseph B Shrager
    Division of Thoracic Surgery, VA Palo Alto Healthcare System, Stanford Medical Center, Stanford University School of Medicine, 300 Pasteur Drive, 2nd Floor, Falk Building, Stanford, CA 94305 5407, USA
    Thorac Surg Clin 23:257-66. 2013
  2. ncbi Extended transcervical thymectomy: the ultimate minimally invasive approach
    Joseph B Shrager
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
    Ann Thorac Surg 89:S2128-34. 2010
  3. doi Intraoperative and postoperative management of air leaks in patients with emphysema
    Joseph B Shrager
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford Hospitals and Clinics, 2nd Floor, Falk Building, 300 Pasteur Drive, Stanford, CA 94305 5407, USA
    Thorac Surg Clin 19:223-31, ix. 2009
  4. ncbi Mediastinoscopy: still the gold standard
    Joseph B Shrager
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, USA
    Ann Thorac Surg 89:S2084-9. 2010
  5. doi Benign emptying of the postpneumonectomy space
    Robert E Merritt
    Division of Thoracic Surgery, Stanford School of Medicine, Stanford Hospitals and Clinics, Stanford, California 94305 5407, USA
    Ann Thorac Surg 92:1076-81; discussion 1081-2. 2011
  6. doi Lymph node evaluation achieved by open lobectomy compared with thoracoscopic lobectomy for N0 lung cancer
    Robert E Merritt
    Department of Cardiothoracic Surgery, Division of Thoracic Surgery, Stanford University School of Medicine, Stanford, California Electronic address
    Ann Thorac Surg 96:1171-7. 2013
  7. pmc Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer
    Manhong Wu
    Department of Anesthesia, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Rapid Commun Mass Spectrom 27:2091-8. 2013
  8. doi A dominant adenocarcinoma with multifocal ground glass lesions does not behave as advanced disease
    Bo Gu
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, USA
    Ann Thorac Surg 96:411-8. 2013
  9. pmc Prognostic PET 18F-FDG uptake imaging features are associated with major oncogenomic alterations in patients with resected non-small cell lung cancer
    Viswam S Nair
    Division of Pulmonary and Critical Care Medicine, Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA
    Cancer Res 72:3725-34. 2012
  10. doi Morbidity and mortality after esophagectomy following neoadjuvant chemoradiation
    Robert E Merritt
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California 94305 5407, USA
    Ann Thorac Surg 92:2034-40. 2011

Collaborators

Detail Information

Publications29

  1. doi Approach to the patient with multiple lung nodules
    Joseph B Shrager
    Division of Thoracic Surgery, VA Palo Alto Healthcare System, Stanford Medical Center, Stanford University School of Medicine, 300 Pasteur Drive, 2nd Floor, Falk Building, Stanford, CA 94305 5407, USA
    Thorac Surg Clin 23:257-66. 2013
    ..A suggested clinical approach to each of these types of multifocal tumors, solid and lepidic, is proposed in this article...
  2. ncbi Extended transcervical thymectomy: the ultimate minimally invasive approach
    Joseph B Shrager
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
    Ann Thorac Surg 89:S2128-34. 2010
    ..The major surgical complication rate is 0.7%. We believe that this less morbid and less costly operation is a very reasonable choice in the surgical treatment of myasthenia gravis...
  3. doi Intraoperative and postoperative management of air leaks in patients with emphysema
    Joseph B Shrager
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford Hospitals and Clinics, 2nd Floor, Falk Building, 300 Pasteur Drive, Stanford, CA 94305 5407, USA
    Thorac Surg Clin 19:223-31, ix. 2009
    ..It reviews the data available on newer and more traditional options for the prophylaxis and management of air leaks and offers the authors' opinions about the optimal approaches in various clinical situations...
  4. ncbi Mediastinoscopy: still the gold standard
    Joseph B Shrager
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, USA
    Ann Thorac Surg 89:S2084-9. 2010
    ..There are scenarios in which EBUS is preferable to mediastinoscopy. However, for routine staging of the upper mediastinum in non-small cell lung cancer, the benefits of EBUS over mediastinoscopy remain unproven...
  5. doi Benign emptying of the postpneumonectomy space
    Robert E Merritt
    Division of Thoracic Surgery, Stanford School of Medicine, Stanford Hospitals and Clinics, Stanford, California 94305 5407, USA
    Ann Thorac Surg 92:1076-81; discussion 1081-2. 2011
    ..We have discovered however that in rare asymptomatic patients, this event may not require aggressive surgical treatment...
  6. doi Lymph node evaluation achieved by open lobectomy compared with thoracoscopic lobectomy for N0 lung cancer
    Robert E Merritt
    Department of Cardiothoracic Surgery, Division of Thoracic Surgery, Stanford University School of Medicine, Stanford, California Electronic address
    Ann Thorac Surg 96:1171-7. 2013
    ..This study compared the completeness of the lymph node dissection or sampling for patients undergoing lobectomy by open thoracotomy vs VATS for clinical N0 lung cancer...
  7. pmc Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer
    Manhong Wu
    Department of Anesthesia, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Rapid Commun Mass Spectrom 27:2091-8. 2013
    ..Although lung cancer is among the leading causes of cancer-related mortality worldwide, the lung tumor metabolome has not been fully characterized...
  8. doi A dominant adenocarcinoma with multifocal ground glass lesions does not behave as advanced disease
    Bo Gu
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, USA
    Ann Thorac Surg 96:411-8. 2013
    ..The optimal approach in this circumstance (often nonsmokers) remains unclear. We evaluated a general strategy of anatomic resection of the dominant tumor (DT) and wedge resection of accessible ipsilateral GGOs...
  9. pmc Prognostic PET 18F-FDG uptake imaging features are associated with major oncogenomic alterations in patients with resected non-small cell lung cancer
    Viswam S Nair
    Division of Pulmonary and Critical Care Medicine, Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA
    Cancer Res 72:3725-34. 2012
    ..Together, our findings suggest that leveraging tumor genomics with an expanded collection of PET-FDG imaging features may enhance our understanding of FDG uptake as an imaging biomarker beyond its association with glycolysis...
  10. doi Morbidity and mortality after esophagectomy following neoadjuvant chemoradiation
    Robert E Merritt
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California 94305 5407, USA
    Ann Thorac Surg 92:2034-40. 2011
    ..A survival benefit has not been definitively established, and there is concern that chemoradiation may increase postoperative morbidity and mortality...
  11. pmc An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer
    Viswam S Nair
    Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 8:e67733. 2013
    ....
  12. doi mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases
    Huibin Tang
    1Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    Sci Signal 7:ra18. 2014
    ..This mTORC1-FoxO axis represents a potential therapeutic target in neurogenic muscle atrophy. ..
  13. doi Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation
    Huibin Tang
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford School of Medicine, VA Palo Alto Health Care System, 300 Pasteur Drive, Stanford, California 94305 5407, USA
    Muscle Nerve 48:272-8. 2013
    ..Previous studies of VIDA have relied on human biopsies or a rat model. If MV can induce diaphragm atrophy in mice, then mechanistic study of VIDA could be explored via genetic manipulation...
  14. ncbi Tumor volume as a potential imaging-based risk-stratification factor in trimodality therapy for locally advanced non-small cell lung cancer
    Margaret M Kozak
    Department of Radiation Oncology, Stanford University, Stanford, California 94305 5847, USA
    J Thorac Oncol 6:920-6. 2011
    ....
  15. pmc Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems
    Huibin Tang
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California 94305 5407, USA
    FASEB J 26:4710-21. 2012
    ..These findings suggest that oxidative stress-responsive microRNA-320a may regulate glycolysis broadly within nature...
  16. pmc Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis
    Huibin Tang
    Division of Thoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    FASEB J 25:2921-36. 2011
    ..We thus identify a novel Fos/FoxO1/Stat3-Bim intrinsic apoptotic pathway and establish the centrality of oxidative stress in the development of VIDD. This information may help in the design of specific drugs to prevent this condition...
  17. doi Improved survival after pulmonary metastasectomy for soft tissue sarcoma
    Jarrod D Predina
    Division of Thoracic Surgery, Joan Karnell Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Thorac Oncol 6:913-9. 2011
    ..With improved patient selection criteria and advanced chemotherapy agents, we hypothesized that survival after metastasectomy for STS has improved in recent years...
  18. ncbi Extended transcervical thymectomy in the treatment of myasthenia gravis
    Sanjay G Khicha
    Division of Thoracic Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, PA 19104, USA
    Ann N Y Acad Sci 1132:336-43. 2008
    ....
  19. ncbi Thoracoscopic lobectomy is associated with acceptable morbidity and mortality in patients with predicted postoperative forced expiratory volume in 1 second or diffusing capacity for carbon monoxide less than 40% of normal
    Bryan M Burt
    Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, Calif Electronic address
    J Thorac Cardiovasc Surg 148:19-29.e1. 2014
    ..We hypothesized that VATS lobectomy would be associated with acceptable morbidity and mortality at ppoFEV1% and ppoDLCO% values < 40%...
  20. ncbi A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal
    Yanyan Zheng
    Cancer Biology Program, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cancer Cell 24:59-74. 2013
    ..The TPC population is enriched after chemotherapy, and the gene signature of mouse TPCs correlates with poor prognosis in human NSCLC. The role of Notch3 in tumor propagation may provide a therapeutic target for NSCLC. ..
  21. doi Early outcomes after bilateral thoracoscopy versus median sternotomy for lung volume reduction
    Matthew M Puc
    From the Division of Thoracic Surgery, Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA USA Division of Thoracic Surgery, Department of Surgery, St Luke s Health Network, Bethlehem, PA USA and Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA USA
    Innovations (Phila) 5:97-102. 2010
    ..Our hypothesis was that a VATS approach would provide equivalent or less morbidity than MS despite being applied to a group of patients subjectively selected to be higher risk than those undergoing MS...
  22. doi Evidence-based suggestions for management of air leaks
    Robert E Merritt
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford Medical Center, 2nd floor Falk Building, 300 Pasteur Drive, Stanford, CA 94305, USA
    Thorac Surg Clin 20:435-48. 2010
    ..This article provides a review of the available evidence-based literature that addresses the efficacy of the options currently available to prevent and manage AALs. Management suggestions based on this literature are presented...
  23. ncbi An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
    Aaron M Newman
    1 Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, USA 2 Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University, Stanford, California, USA 3
    Nat Med 20:548-54. 2014
    ..Finally, we evaluated biopsy-free tumor screening and genotyping with CAPP-Seq. We envision that CAPP-Seq could be routinely applied clinically to detect and monitor diverse malignancies, thus facilitating personalized cancer therapy. ..
  24. ncbi Malignant pleural mesothelioma and the Society of Thoracic Surgeons Database: An analysis of surgical morbidity and mortality
    Bryan M Burt
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, Calif
    J Thorac Cardiovasc Surg 148:30-5. 2014
    ..For comparison, we examined early outcomes of pleurectomy/decortication and extrapleural pneumonectomy from a broader group of centers/surgeons participating in the Society of Thoracic Surgeons-General Thoracic Database...
  25. doi Indications for surgery in patients with localized pulmonary infection
    Robert E Merritt
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Thorac Surg Clin 22:325-32. 2012
    ..This article reviews the indications for surgical intervention in the treatment of common infections involving the lung, and also focuses on the general approaches to their management...
  26. doi Prophylaxis and management of atrial fibrillation after general thoracic surgery
    Robert E Merritt
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Thorac Surg Clin 22:13-23, v. 2012
    ..High-risk patients with history of stroke or transient ischemic attack, or with two or more risk factors for thromboembolism should receive anticoagulation therapy...
  27. doi Management of alveolar air leaks after pulmonary resection
    Sunil Singhal
    Division of Thoracic Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 89:1327-35. 2010
    ..We used available literature and expert consensus to formulate suggestions regarding the preferred approaches to both routine and prolonged alveolar air leaks. This review summarizes our findings...
  28. ncbi Outcomes after 151 extended transcervical thymectomies for myasthenia gravis
    Joseph B Shrager
    Department of Surgery, Division of Thoracic Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 82:1863-9. 2006
    ..The ideal operative technique for thymectomy in myasthenia gravis (MG) remains controversial. We present the largest series of extended transcervical thymectomy to provide outcomes data to compare with transsternal procedures...
  29. ncbi Parasternal intercostal muscle remodeling in severe chronic obstructive pulmonary disease
    Sanford Levine
    Department of Surgery, Division of Thoracic Surgery, University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    J Appl Physiol (1985) 101:1297-302. 2006
    ..The physiological significance of this difference in remodeling between these two inspiratory rib cage muscles remains to be elucidated...